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The map label for this gene is murA

Identifier: 68535466

GI number: 68535466

Start: 470747

End: 472003

Strand: Direct

Name: murA

Synonym: jk0398

Alternate gene names: 68535466

Gene position: 470747-472003 (Clockwise)

Preceding gene: 68535465

Following gene: 68535469

Centisome position: 19.12

GC content: 59.9

Gene sequence:

>1257_bases
GTGAAAGACAGCTTCGTAGTGACAGGTGGAACCAGACTGCAGGGCGCCATCAAGGTATCCGGCGCCAAGAACAGCGTGCT
TAAGCTAATGTCGGCGGCGCTTTTAGCACCCGGAACCACCATGTTGACCAATTGCCCCGAAATCGCCGACGTGCCCTACA
TGGCAGAAGTTCTGCGTGGCCTGGGTTGTGAGGTGGAGCTCGATGGCGACGTCGTGCGCATCACGACCCCGGAGAGTATC
GAGTACAACGCAGACTTTGAGGCCGTGCGTCAGTTCCGTGCCTCCGTTGCTGTGCTGGGGCCGCTAACCTCGCGATGCCA
CAAGGCGCGGGTTGCTCTTCCCGGTGGTGACGCCATCGGTTCCCGTCCCCTCGATATGCACCAATCTGGTCTAGAGCTGC
TGGGTGCAACCACCAAGATCGAACACGGTTGCCTGGTCGCCGAGGCTGAAGAACTTCGTGGTGCACAAATCAAGCTGGAC
TTCCCGTCGGTGGGTGCAACAGAAAACATTCTGACTGCCGCGGTGCTGGCGGAGGGCACAACCACGCTGGACAATGCGGC
TCGGGAGCCGGAGATCGTGGATCTGTGCAACATGCTGGTAGCGATGGGCGCCAAGATCGACGGTGCCGGTTCCAACACCA
TCACCGTGGAAGGTGTGGATCGGCTGAACCCGGTGGATCACGAGGTTGTCGGCGATCGAATTGTCGCTGGCACTTGGGCG
TATGCGGCCGCGATGACGCGAGGAGACATTACGGTCGGCGGTATCGATCCACAGCACTTGCACCTGGTTCTGGAGAAGCT
AAAGCTCGCCGGCGCCCAGGTTGAGACTTATCCGACTGGCTTTAGGGTGGTGCAGAACGAACGCCCCAAGGCGGTGGACT
ACCAAACGCTACCTTTCCCCGGATTCCCAACTGATCTGCAGCCGATGGCGATTGCACTGTGCACGGTGAGCGAGGGGATG
AGCGTGATCACGGAGAATATCTTTGAGTCCCGTTTCCGATTTGTCGACGAGATGATGCGCTTGGGTGCAGATGCCAGCAT
CGACGGCCACCATGTAGTTATTCGGGGCAGGGAGCAGCTTTCCTCTGCGCCAGTATGGAGCTCCGACATTCGTGCGGGTG
CAGGCCTAGTACTAGCCGGCCTGGTAGCGGATGGAAAGACTGAAGTGCACGACGTGTACCACATCGATCGCGGTTACCCG
GAGTTCCCGGAACAGCTGCGCTCGCTCGGGGCGGAAGTGGAGCGCGTGCAGCGTTAG

Upstream 100 bases:

>100_bases
TTGCCCTGATATCAATTCTGCGAGGCCCTCGAGTAGCTTCAAGCAGCTCTAAACAATCGCTCCGCTTTGCGCGGGGCGAT
TTTTTTATAGGCTGGGTGGC

Downstream 100 bases:

>100_bases
AAGGCTGTATGCGAGGGGCTAAGCCTCTCGGACGCCTGGAACGCCCCTCAAGTGTGTTGCCAACACTTTATAAAAACCAC
CTCTGGCCTGCGGGTTTGTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKDSFVVTGGTRLQGAIKVSGAKNSVLKLMSAALLAPGTTMLTNCPEIADVPYMAEVLRGLGCEVELDGDVVRITTPESI
EYNADFEAVRQFRASVAVLGPLTSRCHKARVALPGGDAIGSRPLDMHQSGLELLGATTKIEHGCLVAEAEELRGAQIKLD
FPSVGATENILTAAVLAEGTTTLDNAAREPEIVDLCNMLVAMGAKIDGAGSNTITVEGVDRLNPVDHEVVGDRIVAGTWA
YAAAMTRGDITVGGIDPQHLHLVLEKLKLAGAQVETYPTGFRVVQNERPKAVDYQTLPFPGFPTDLQPMAIALCTVSEGM
SVITENIFESRFRFVDEMMRLGADASIDGHHVVIRGREQLSSAPVWSSDIRAGAGLVLAGLVADGKTEVHDVYHIDRGYP
EFPEQLRSLGAEVERVQR

Sequences:

>Translated_418_residues
MKDSFVVTGGTRLQGAIKVSGAKNSVLKLMSAALLAPGTTMLTNCPEIADVPYMAEVLRGLGCEVELDGDVVRITTPESI
EYNADFEAVRQFRASVAVLGPLTSRCHKARVALPGGDAIGSRPLDMHQSGLELLGATTKIEHGCLVAEAEELRGAQIKLD
FPSVGATENILTAAVLAEGTTTLDNAAREPEIVDLCNMLVAMGAKIDGAGSNTITVEGVDRLNPVDHEVVGDRIVAGTWA
YAAAMTRGDITVGGIDPQHLHLVLEKLKLAGAQVETYPTGFRVVQNERPKAVDYQTLPFPGFPTDLQPMAIALCTVSEGM
SVITENIFESRFRFVDEMMRLGADASIDGHHVVIRGREQLSSAPVWSSDIRAGAGLVLAGLVADGKTEVHDVYHIDRGYP
EFPEQLRSLGAEVERVQR
>Mature_418_residues
MKDSFVVTGGTRLQGAIKVSGAKNSVLKLMSAALLAPGTTMLTNCPEIADVPYMAEVLRGLGCEVELDGDVVRITTPESI
EYNADFEAVRQFRASVAVLGPLTSRCHKARVALPGGDAIGSRPLDMHQSGLELLGATTKIEHGCLVAEAEELRGAQIKLD
FPSVGATENILTAAVLAEGTTTLDNAAREPEIVDLCNMLVAMGAKIDGAGSNTITVEGVDRLNPVDHEVVGDRIVAGTWA
YAAAMTRGDITVGGIDPQHLHLVLEKLKLAGAQVETYPTGFRVVQNERPKAVDYQTLPFPGFPTDLQPMAIALCTVSEGM
SVITENIFESRFRFVDEMMRLGADASIDGHHVVIRGREQLSSAPVWSSDIRAGAGLVLAGLVADGKTEVHDVYHIDRGYP
EFPEQLRSLGAEVERVQR

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=46.7625899280576, Blast_Score=350, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_CORJK (Q4JXA4)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250171.1
- ProteinModelPortal:   Q4JXA4
- SMR:   Q4JXA4
- STRING:   Q4JXA4
- GeneID:   3432771
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0398
- NMPDR:   fig|306537.3.peg.1594
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   CJEI306537:JK0398-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44679; Mature: 44679

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDSFVVTGGTRLQGAIKVSGAKNSVLKLMSAALLAPGTTMLTNCPEIADVPYMAEVLRG
CCCCEEEECCCEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHH
LGCEVELDGDVVRITTPESIEYNADFEAVRQFRASVAVLGPLTSRCHKARVALPGGDAIG
CCCEEEECCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCC
SRPLDMHQSGLELLGATTKIEHGCLVAEAEELRGAQIKLDFPSVGATENILTAAVLAEGT
CCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCC
TTLDNAAREPEIVDLCNMLVAMGAKIDGAGSNTITVEGVDRLNPVDHEVVGDRIVAGTWA
CHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHCCCCCHHHHCCEEEECHHH
YAAAMTRGDITVGGIDPQHLHLVLEKLKLAGAQVETYPTGFRVVQNERPKAVDYQTLPFP
HHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCEEECCCC
GFPTDLQPMAIALCTVSEGMSVITENIFESRFRFVDEMMRLGADASIDGHHVVIRGREQL
CCCCCCCHHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHH
SSAPVWSSDIRAGAGLVLAGLVADGKTEVHDVYHIDRGYPEFPEQLRSLGAEVERVQR
CCCCCCCHHHCCCCCCEEEEECCCCCCHHHHEEEECCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDSFVVTGGTRLQGAIKVSGAKNSVLKLMSAALLAPGTTMLTNCPEIADVPYMAEVLRG
CCCCEEEECCCEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHH
LGCEVELDGDVVRITTPESIEYNADFEAVRQFRASVAVLGPLTSRCHKARVALPGGDAIG
CCCEEEECCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCC
SRPLDMHQSGLELLGATTKIEHGCLVAEAEELRGAQIKLDFPSVGATENILTAAVLAEGT
CCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCC
TTLDNAAREPEIVDLCNMLVAMGAKIDGAGSNTITVEGVDRLNPVDHEVVGDRIVAGTWA
CHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHCCCCCHHHHCCEEEECHHH
YAAAMTRGDITVGGIDPQHLHLVLEKLKLAGAQVETYPTGFRVVQNERPKAVDYQTLPFP
HHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCEEECCCC
GFPTDLQPMAIALCTVSEGMSVITENIFESRFRFVDEMMRLGADASIDGHHVVIRGREQL
CCCCCCCHHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHH
SSAPVWSSDIRAGAGLVLAGLVADGKTEVHDVYHIDRGYPEFPEQLRSLGAEVERVQR
CCCCCCCHHHCCCCCCEEEEECCCCCCHHHHEEEECCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA