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The map label for this gene is mshD

Identifier: 68535441

GI number: 68535441

Start: 448966

End: 450003

Strand: Direct

Name: mshD

Synonym: jk0376

Alternate gene names: 68535441

Gene position: 448966-450003 (Clockwise)

Preceding gene: 68535438

Following gene: 68535442

Centisome position: 18.23

GC content: 58.96

Gene sequence:

>1038_bases
ATGGCTATTACCTACGACACATATGAAGACCTGTGGGAGCACTCTGAGGTGTTGGAGGGGGTTCACGAGGTACTGAGCGA
AGTCGCTGAGGTGGATGGCGTCCCTGCCATTAGCGAAGCTTTCTTACGCGGCATTGACGAAGATCGTGGGCATAAGCACG
TGGTGGCAATGAACGGTGACCGTGTGGCCGGTGTGCTGGCGATTGACCCGGACCGCGTGATCGAGCTGGCCGTTGCCCCA
GAAGTTCGTCATAGCAGGGTGGGGATTGCCTTGTTTGAGGCTCTACGCGATCAGCTGGGGGTGAGCGGGGGAATTGACGT
TTGGGCGCACGGAGATTCCGCCGGCGCGCAGCGCTTTGTGGAGTCGCTGGATGCCCGTCGAACCCGCGAGCTGCTGAAGA
TGTCCGTGGATTGCCCTCCGGCGACGAAGGCTGCCAAGGCTATGGAGGCAGGCGGAGCAGAAGCGGAGAAACGCTGCGCG
GAGCAGGATTTTGAAGTCCTGTCCTACACCGAATCCGTAGCGCGCTTCGATGCGGATTCCGTGGACGCCGAGTGGGTACG
CATCAATAACGAGGCCTTCGCATGGCACCCGGAGCAGGGTGGTTGGGACGTGGACTATTTGCGTTCTGCTCGCGACACCA
ATTGGTTCGACCCGGACGGGGTGCTCATGTTGTGGGTGCGGGACGAGAATTCCGCTGCTGAGCGAGTAGGGATTCCCTGC
GCAGCAAACGGCGGCGAAGGGAATGATGATGTCTTCCGCCTGGTGGGTTTCCACTGGACGAAGATTCCACTGGAGGAAAA
GGAAAAGGATGCCGGCGAGCGGACGGGCGAAGTATATGTTGTGTGCCTAGCTGACGATGCTCGTGGAAGAGGGCTAGGGC
AGGCGATCACTCAATTGGGCATGAAGTCGTTGTTGGAAAACGGTTGTGGCCGCATTGAGCTCTATGTGGAGGGCGATAAC
GCGCCAGCGGTCTCTACCTATAAACGACTCGGTTTCGAAGTTGTGCACACCGACGTGGTCTATCGCGGTCGTCTCTAA

Upstream 100 bases:

>100_bases
CTTATTGACGCCACGCCTCCGCTGCTTCAAACTCAGCGAAGCGTCAAGAAACCCTTTAAATCTTCCCCACGACGGGAGGA
TTTAAGGGACAATCGAGGGC

Downstream 100 bases:

>100_bases
TCGGCCCTGTTGGGTTTTAGTTGAGCTCTGAGGGTTCTTATGCTGCTCTTGAACAGGCAGCCTTATTGTTTCCTCAAGAT
ATCCTGAGAAGGTCTGGTGC

Product: putative acetyltransferase

Products: NA

Alternate protein names: MSH acetyltransferase; Mycothiol synthase

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MAITYDTYEDLWEHSEVLEGVHEVLSEVAEVDGVPAISEAFLRGIDEDRGHKHVVAMNGDRVAGVLAIDPDRVIELAVAP
EVRHSRVGIALFEALRDQLGVSGGIDVWAHGDSAGAQRFVESLDARRTRELLKMSVDCPPATKAAKAMEAGGAEAEKRCA
EQDFEVLSYTESVARFDADSVDAEWVRINNEAFAWHPEQGGWDVDYLRSARDTNWFDPDGVLMLWVRDENSAAERVGIPC
AANGGEGNDDVFRLVGFHWTKIPLEEKEKDAGERTGEVYVVCLADDARGRGLGQAITQLGMKSLLENGCGRIELYVEGDN
APAVSTYKRLGFEVVHTDVVYRGRL

Sequences:

>Translated_345_residues
MAITYDTYEDLWEHSEVLEGVHEVLSEVAEVDGVPAISEAFLRGIDEDRGHKHVVAMNGDRVAGVLAIDPDRVIELAVAP
EVRHSRVGIALFEALRDQLGVSGGIDVWAHGDSAGAQRFVESLDARRTRELLKMSVDCPPATKAAKAMEAGGAEAEKRCA
EQDFEVLSYTESVARFDADSVDAEWVRINNEAFAWHPEQGGWDVDYLRSARDTNWFDPDGVLMLWVRDENSAAERVGIPC
AANGGEGNDDVFRLVGFHWTKIPLEEKEKDAGERTGEVYVVCLADDARGRGLGQAITQLGMKSLLENGCGRIELYVEGDN
APAVSTYKRLGFEVVHTDVVYRGRL
>Mature_344_residues
AITYDTYEDLWEHSEVLEGVHEVLSEVAEVDGVPAISEAFLRGIDEDRGHKHVVAMNGDRVAGVLAIDPDRVIELAVAPE
VRHSRVGIALFEALRDQLGVSGGIDVWAHGDSAGAQRFVESLDARRTRELLKMSVDCPPATKAAKAMEAGGAEAEKRCAE
QDFEVLSYTESVARFDADSVDAEWVRINNEAFAWHPEQGGWDVDYLRSARDTNWFDPDGVLMLWVRDENSAAERVGIPCA
ANGGEGNDDVFRLVGFHWTKIPLEEKEKDAGERTGEVYVVCLADDARGRGLGQAITQLGMKSLLENGCGRIELYVEGDNA
PAVSTYKRLGFEVVHTDVVYRGRL

Specific function: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol

COG id: COG0456

COG function: function code R; Acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 N-acetyltransferase domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSHD_CORJK (Q4JXC9)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250146.1
- ProteinModelPortal:   Q4JXC9
- SMR:   Q4JXC9
- STRING:   Q4JXC9
- GeneID:   3433890
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0376
- NMPDR:   fig|306537.3.peg.1476
- eggNOG:   COG0456
- HOGENOM:   HBG292446
- OMA:   GFHWTKI
- ProtClustDB:   CLSK2309145
- BioCyc:   CJEI306537:JK0376-MONOMER
- HAMAP:   MF_01698
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR017813
- Gene3D:   G3DSA:3.40.630.30
- TIGRFAMs:   TIGR03448

Pfam domain/function: PF00583 Acetyltransf_1; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.189

Molecular weight: Translated: 37945; Mature: 37813

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS51186 GNAT

Important sites: BINDING 39-39 BINDING 198-198 BINDING 261-261 BINDING 277-277 BINDING 315-315

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITYDTYEDLWEHSEVLEGVHEVLSEVAEVDGVPAISEAFLRGIDEDRGHKHVVAMNGD
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCC
RVAGVLAIDPDRVIELAVAPEVRHSRVGIALFEALRDQLGVSGGIDVWAHGDSAGAQRFV
CEEEEEEECHHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHH
ESLDARRTRELLKMSVDCPPATKAAKAMEAGGAEAEKRCAEQDFEVLSYTESVARFDADS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VDAEWVRINNEAFAWHPEQGGWDVDYLRSARDTNWFDPDGVLMLWVRDENSAAERVGIPC
CCCEEEEECCCEEEECCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHCCCCE
AANGGEGNDDVFRLVGFHWTKIPLEEKEKDAGERTGEVYVVCLADDARGRGLGQAITQLG
ECCCCCCCHHHHHEECCEEEECCCHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHH
MKSLLENGCGRIELYVEGDNAPAVSTYKRLGFEVVHTDVVYRGRL
HHHHHHCCCCEEEEEEECCCCCHHHHHHHCCEEEEEEEEEEECCC
>Mature Secondary Structure 
AITYDTYEDLWEHSEVLEGVHEVLSEVAEVDGVPAISEAFLRGIDEDRGHKHVVAMNGD
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCC
RVAGVLAIDPDRVIELAVAPEVRHSRVGIALFEALRDQLGVSGGIDVWAHGDSAGAQRFV
CEEEEEEECHHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHH
ESLDARRTRELLKMSVDCPPATKAAKAMEAGGAEAEKRCAEQDFEVLSYTESVARFDADS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VDAEWVRINNEAFAWHPEQGGWDVDYLRSARDTNWFDPDGVLMLWVRDENSAAERVGIPC
CCCEEEEECCCEEEECCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHCCCCE
AANGGEGNDDVFRLVGFHWTKIPLEEKEKDAGERTGEVYVVCLADDARGRGLGQAITQLG
ECCCCCCCHHHHHEECCEEEECCCHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHH
MKSLLENGCGRIELYVEGDNAPAVSTYKRLGFEVVHTDVVYRGRL
HHHHHHCCCCEEEEEEECCCCCHHHHHHHCCEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA