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The map label for this gene is ptrB [H]

Identifier: 68535416

GI number: 68535416

Start: 421603

End: 423837

Strand: Direct

Name: ptrB [H]

Synonym: jk0351

Alternate gene names: 68535416

Gene position: 421603-423837 (Clockwise)

Preceding gene: 68535415

Following gene: 68535417

Centisome position: 17.12

GC content: 64.56

Gene sequence:

>2235_bases
ATGGCGCGTATGCCTAATAACGACGCGCCCCAGACAGCTAACAACCCAATCGCAGCCCCGCCGGTTGCGAAGCGGGTGCC
GCACACCCGCACCTTCCACGGCCGTGAGTTCGTCGATAACTACGAGTGGCTGCGTGACAAGGAAAACGCGGAGGTCCGCC
AGCACTTAGAGGCGGAGAACGCCTGGACTGCTCAGCAGACCGCCCACCTCAAGCCGTTGGAAGACCGCCTGTTCGAGGAG
GTTAAGGCCCGGGTGCAGGAGACGGATATGTCCCTACCCGTGCGTTCCGAGGGCTGGTGGTATTTCTCCCGCACCGAGGA
GGGCAAAAGCTATGGCACCATGTGCCGAGTTCCCATCGCCGATCAAGACGACTGGACCCCACCGACCATCGAACCGGGAG
TTCCCGCGCCGGGCGAGGAGACCTTCCTGGACTGCAACGCCCTAGCAGAGGGCAAGGAGTTCTTTAGCCTGGGTGCGGCC
AGCGTAACCCAGGACGGCACGCGCTTGGCCTATTCGGTGGACGAGACCGGCTCCGAGCGCTTCACCCTGCGCATCCGCGA
CCTCACCACGGGGGAGGACCTGGAAGACGAGATCGAGGATGTCTTCTACGGAGCCACCTGGGTCGGCAGGGATACCGTGT
ACTACCAGCGCGTGGATGAAGCGTGGCGACCACACGAGATTTGGCGCCACACAGTCGGTGAGGGCGTCGATAAAGACGAG
CTGGTGTACCGCGAAGACGACGAACGGTTCTGGACGGGCGTGGCAACCACCCGCTCCGAGCGCTACTTGCTGGTCCACAC
GGGCTCGAAGGTGACCAGCGAGGTGTGGTACCTCGACCTGGAGGATCCGAATGCCGAGCTGACCTGTGTAATCCCGCGCG
AGGCCAATGTGGAGTACGGAGTGGATCACGCAGTTGTGGGCGGCCTGGATCTGTGGCTGGTGCTGCATAACAAGACCGGT
GCGAACAGCGAGCTCGGCTACCACCCAACCGGCCAGATCGCCGCGTGGGACGACGTGCAAGCGCTAGTGCCGCACCGCGA
GGATGCGCGCCTGGAGGGCGTGGATGTCTTCAGCGACCACATTGTCCTCGAAGCTCGGGAGAATGCGCTGGAGACCAGCT
ACATCATGAAGCTTGGTGACGCCGACACCTCGACCGGCGACTCTTCCGCCCCGGCCTTTGGCGAGTTCGAGCGGATCGAA
TTCCCCGGGGAACTCTGCGGGGTTGGGGCCGTGGGCAACAGCGAGTGGGAGAGCCCGGTGCTGCGCGTGGCCTACACCGC
CTTCACCACCCCGCCGCGGATTTACGACATCGACCTGGCGACGGGGGAGAAGATCCTGCGCAAGGAACAGCAGGTGCTGG
CCGACCCGGACGGCCGGGAGTTCGACCCTGCGCAGTACACCTCGCAGCGACTATGGGTGACGGCCGAGGATGGTGCGCGC
ATTCCGGTTTCCCTGATCCACCGCACGGACGTGGACATCACTCAGGCGAACCCGGTGTTGCTGTACGGCTACGGTTCCTA
TGAAAACTGCATCGACCCGGGATTCTCCCTGTTCCGCCTGTCCATGTTGGACCGTGGTGTGGTGTACGCCATCGCGCACG
TCCGCGGCGGTGGCGAGATGGGCCGGCAGTGGTACGACCACGGCAAGGGACTGGAGAAGCGCAACACGTTTACGGACTTC
GTGGCCGTCGCCGACCATCTGCTGCGCGAGGGCATGACCACCCGCGAGCAGATGGTGGCCGAGGGCGGCTCCGCCGGCGG
CATGTTGATGGGTGCTGTGGCTAACCTGGCGGGCGATCGCTTCGCGGGCATCGAGGCCGTGGTTCCTTTCGTGGATCCGC
TGACCAGCATGCTCATGCCGGAGCTGCCGCTGACCGTGACGGAGTGGGACGAGTGGGGTGATCCCTTCCACGACCCGCAG
GTCTACGACTACATGGCGGGCTACGCTCCCTATGAGAACGTTTCGGCCGACCTGACCTATCCGCCGATCCTGGCGGTGAC
CAGCTTGAACGACACCCGCGTGCTGTATGTGGAACCCGCGAAGTGGGTGGCAAAGCTGCGCGAGGTGGGCGCCGAGAACA
CGCTGCTGCGCATCGACATGGAGGCCGGCCACGGCGGCGTATCCGGCCGCTACGCCAAGTGGCGCCAGGCGGCTTTCGAG
ACTGCCTGGGAGCTGGACAGGATGGGGGCTACCGAGCTGCTGGTGGCTGGTGGACCTGAAAGGGGTCAAGAATAG

Upstream 100 bases:

>100_bases
AGAAGCTATCCGGCAAGCGCTTCTCCGACTGGATTGGCCAGTGCGTCTAGGCGACTGCAGTCCCAACCAATTCGGCTCCC
AGTAGTCCTGTCTGAGTAGC

Downstream 100 bases:

>100_bases
CGGCTCAGAGCCTTTAACAACTCGACGCCCAGATGTAGGGCGGGCGTTACCTCCCGTTCACCTGTGTTGTGCAGGCTAAG
TATCTATGAGCCCCGCACAG

Product: hypothetical protein

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 744; Mature: 743

Protein sequence:

>744_residues
MARMPNNDAPQTANNPIAAPPVAKRVPHTRTFHGREFVDNYEWLRDKENAEVRQHLEAENAWTAQQTAHLKPLEDRLFEE
VKARVQETDMSLPVRSEGWWYFSRTEEGKSYGTMCRVPIADQDDWTPPTIEPGVPAPGEETFLDCNALAEGKEFFSLGAA
SVTQDGTRLAYSVDETGSERFTLRIRDLTTGEDLEDEIEDVFYGATWVGRDTVYYQRVDEAWRPHEIWRHTVGEGVDKDE
LVYREDDERFWTGVATTRSERYLLVHTGSKVTSEVWYLDLEDPNAELTCVIPREANVEYGVDHAVVGGLDLWLVLHNKTG
ANSELGYHPTGQIAAWDDVQALVPHREDARLEGVDVFSDHIVLEARENALETSYIMKLGDADTSTGDSSAPAFGEFERIE
FPGELCGVGAVGNSEWESPVLRVAYTAFTTPPRIYDIDLATGEKILRKEQQVLADPDGREFDPAQYTSQRLWVTAEDGAR
IPVSLIHRTDVDITQANPVLLYGYGSYENCIDPGFSLFRLSMLDRGVVYAIAHVRGGGEMGRQWYDHGKGLEKRNTFTDF
VAVADHLLREGMTTREQMVAEGGSAGGMLMGAVANLAGDRFAGIEAVVPFVDPLTSMLMPELPLTVTEWDEWGDPFHDPQ
VYDYMAGYAPYENVSADLTYPPILAVTSLNDTRVLYVEPAKWVAKLREVGAENTLLRIDMEAGHGGVSGRYAKWRQAAFE
TAWELDRMGATELLVAGGPERGQE

Sequences:

>Translated_744_residues
MARMPNNDAPQTANNPIAAPPVAKRVPHTRTFHGREFVDNYEWLRDKENAEVRQHLEAENAWTAQQTAHLKPLEDRLFEE
VKARVQETDMSLPVRSEGWWYFSRTEEGKSYGTMCRVPIADQDDWTPPTIEPGVPAPGEETFLDCNALAEGKEFFSLGAA
SVTQDGTRLAYSVDETGSERFTLRIRDLTTGEDLEDEIEDVFYGATWVGRDTVYYQRVDEAWRPHEIWRHTVGEGVDKDE
LVYREDDERFWTGVATTRSERYLLVHTGSKVTSEVWYLDLEDPNAELTCVIPREANVEYGVDHAVVGGLDLWLVLHNKTG
ANSELGYHPTGQIAAWDDVQALVPHREDARLEGVDVFSDHIVLEARENALETSYIMKLGDADTSTGDSSAPAFGEFERIE
FPGELCGVGAVGNSEWESPVLRVAYTAFTTPPRIYDIDLATGEKILRKEQQVLADPDGREFDPAQYTSQRLWVTAEDGAR
IPVSLIHRTDVDITQANPVLLYGYGSYENCIDPGFSLFRLSMLDRGVVYAIAHVRGGGEMGRQWYDHGKGLEKRNTFTDF
VAVADHLLREGMTTREQMVAEGGSAGGMLMGAVANLAGDRFAGIEAVVPFVDPLTSMLMPELPLTVTEWDEWGDPFHDPQ
VYDYMAGYAPYENVSADLTYPPILAVTSLNDTRVLYVEPAKWVAKLREVGAENTLLRIDMEAGHGGVSGRYAKWRQAAFE
TAWELDRMGATELLVAGGPERGQE
>Mature_743_residues
ARMPNNDAPQTANNPIAAPPVAKRVPHTRTFHGREFVDNYEWLRDKENAEVRQHLEAENAWTAQQTAHLKPLEDRLFEEV
KARVQETDMSLPVRSEGWWYFSRTEEGKSYGTMCRVPIADQDDWTPPTIEPGVPAPGEETFLDCNALAEGKEFFSLGAAS
VTQDGTRLAYSVDETGSERFTLRIRDLTTGEDLEDEIEDVFYGATWVGRDTVYYQRVDEAWRPHEIWRHTVGEGVDKDEL
VYREDDERFWTGVATTRSERYLLVHTGSKVTSEVWYLDLEDPNAELTCVIPREANVEYGVDHAVVGGLDLWLVLHNKTGA
NSELGYHPTGQIAAWDDVQALVPHREDARLEGVDVFSDHIVLEARENALETSYIMKLGDADTSTGDSSAPAFGEFERIEF
PGELCGVGAVGNSEWESPVLRVAYTAFTTPPRIYDIDLATGEKILRKEQQVLADPDGREFDPAQYTSQRLWVTAEDGARI
PVSLIHRTDVDITQANPVLLYGYGSYENCIDPGFSLFRLSMLDRGVVYAIAHVRGGGEMGRQWYDHGKGLEKRNTFTDFV
AVADHLLREGMTTREQMVAEGGSAGGMLMGAVANLAGDRFAGIEAVVPFVDPLTSMLMPELPLTVTEWDEWGDPFHDPQV
YDYMAGYAPYENVSADLTYPPILAVTSLNDTRVLYVEPAKWVAKLREVGAENTLLRIDMEAGHGGVSGRYAKWRQAAFET
AWELDRMGATELLVAGGPERGQE

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=729, Percent_Identity=23.5939643347051, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI284172420, Length=547, Percent_Identity=27.7879341864717, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI284172413, Length=547, Percent_Identity=27.7879341864717, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI70778815, Length=547, Percent_Identity=27.7879341864717, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI284172438, Length=547, Percent_Identity=27.7879341864717, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI284172431, Length=547, Percent_Identity=27.7879341864717, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI108860686, Length=302, Percent_Identity=31.4569536423841, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI108860692, Length=220, Percent_Identity=33.6363636363636, Blast_Score=118, Evalue=2e-26,
Organism=Escherichia coli, GI1788150, Length=714, Percent_Identity=37.2549019607843, Blast_Score=449, Evalue=1e-127,
Organism=Drosophila melanogaster, GI24583414, Length=735, Percent_Identity=24.6258503401361, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI221510989, Length=737, Percent_Identity=23.6092265943012, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 83207; Mature: 83076

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMPNNDAPQTANNPIAAPPVAKRVPHTRTFHGREFVDNYEWLRDKENAEVRQHLEAEN
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCC
AWTAQQTAHLKPLEDRLFEEVKARVQETDMSLPVRSEGWWYFSRTEEGKSYGTMCRVPIA
CCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECC
DQDDWTPPTIEPGVPAPGEETFLDCNALAEGKEFFSLGAASVTQDGTRLAYSVDETGSER
CCCCCCCCCCCCCCCCCCCCCEEECHHHHCCHHHHHCCCCHHCCCCCEEEEEECCCCCCE
FTLRIRDLTTGEDLEDEIEDVFYGATWVGRDTVYYQRVDEAWRPHEIWRHTVGEGVDKDE
EEEEEEECCCCCCHHHHHHHHHCCCEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
LVYREDDERFWTGVATTRSERYLLVHTGSKVTSEVWYLDLEDPNAELTCVIPREANVEYG
EEEEECCCCEEEEEEECCCCCEEEEECCCCEEEEEEEEEECCCCCEEEEEECCCCCCCCC
VDHAVVGGLDLWLVLHNKTGANSELGYHPTGQIAAWDDVQALVPHREDARLEGVDVFSDH
CCHHEECCEEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHCCCCCCCCCCCEEEECCE
IVLEARENALETSYIMKLGDADTSTGDSSAPAFGEFERIEFPGELCGVGAVGNSEWESPV
EEEEEHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCEECCCHHHCCCCCCCCCCCCCCE
LRVAYTAFTTPPRIYDIDLATGEKILRKEQQVLADPDGREFDPAQYTSQRLWVTAEDGAR
EEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECCCCC
IPVSLIHRTDVDITQANPVLLYGYGSYENCIDPGFSLFRLSMLDRGVVYAIAHVRGGGEM
CCEEEEEECCCCEECCCCEEEEECCCCCHHCCCCHHHHHHHHHCCCEEEEEEEECCCHHH
GRQWYDHGKGLEKRNTFTDFVAVADHLLREGMTTREQMVAEGGSAGGMLMGAVANLAGDR
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCC
FAGIEAVVPFVDPLTSMLMPELPLTVTEWDEWGDPFHDPQVYDYMAGYAPYENVSADLTY
CCCHHHHHHHHHHHHHHHCCCCCCEEECCHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
PPILAVTSLNDTRVLYVEPAKWVAKLREVGAENTLLRIDMEAGHGGVSGRYAKWRQAAFE
CCEEEEEECCCCEEEEECCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
TAWELDRMGATELLVAGGPERGQE
HHHHHHHCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
ARMPNNDAPQTANNPIAAPPVAKRVPHTRTFHGREFVDNYEWLRDKENAEVRQHLEAEN
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCC
AWTAQQTAHLKPLEDRLFEEVKARVQETDMSLPVRSEGWWYFSRTEEGKSYGTMCRVPIA
CCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECC
DQDDWTPPTIEPGVPAPGEETFLDCNALAEGKEFFSLGAASVTQDGTRLAYSVDETGSER
CCCCCCCCCCCCCCCCCCCCCEEECHHHHCCHHHHHCCCCHHCCCCCEEEEEECCCCCCE
FTLRIRDLTTGEDLEDEIEDVFYGATWVGRDTVYYQRVDEAWRPHEIWRHTVGEGVDKDE
EEEEEEECCCCCCHHHHHHHHHCCCEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
LVYREDDERFWTGVATTRSERYLLVHTGSKVTSEVWYLDLEDPNAELTCVIPREANVEYG
EEEEECCCCEEEEEEECCCCCEEEEECCCCEEEEEEEEEECCCCCEEEEEECCCCCCCCC
VDHAVVGGLDLWLVLHNKTGANSELGYHPTGQIAAWDDVQALVPHREDARLEGVDVFSDH
CCHHEECCEEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHCCCCCCCCCCCEEEECCE
IVLEARENALETSYIMKLGDADTSTGDSSAPAFGEFERIEFPGELCGVGAVGNSEWESPV
EEEEEHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCEECCCHHHCCCCCCCCCCCCCCE
LRVAYTAFTTPPRIYDIDLATGEKILRKEQQVLADPDGREFDPAQYTSQRLWVTAEDGAR
EEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECCCCC
IPVSLIHRTDVDITQANPVLLYGYGSYENCIDPGFSLFRLSMLDRGVVYAIAHVRGGGEM
CCEEEEEECCCCEECCCCEEEEECCCCCHHCCCCHHHHHHHHHCCCEEEEEEEECCCHHH
GRQWYDHGKGLEKRNTFTDFVAVADHLLREGMTTREQMVAEGGSAGGMLMGAVANLAGDR
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCC
FAGIEAVVPFVDPLTSMLMPELPLTVTEWDEWGDPFHDPQVYDYMAGYAPYENVSADLTY
CCCHHHHHHHHHHHHHHHCCCCCCEEECCHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
PPILAVTSLNDTRVLYVEPAKWVAKLREVGAENTLLRIDMEAGHGGVSGRYAKWRQAAFE
CCEEEEEECCCCEEEEECCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
TAWELDRMGATELLVAGGPERGQE
HHHHHHHCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]