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The map label for this gene is clpB [H]

Identifier: 68535266

GI number: 68535266

Start: 249773

End: 252394

Strand: Direct

Name: clpB [H]

Synonym: jk0201

Alternate gene names: 68535266

Gene position: 249773-252394 (Clockwise)

Preceding gene: 68535261

Following gene: 68535267

Centisome position: 10.14

GC content: 64.8

Gene sequence:

>2622_bases
ATGACGAGCTTCAACCCCACCACAATGACCCAGTCTGCAATGCAGGCTGCACTCCAGGATGCCTCCGCCAAGGGCAACCC
GGACATTCGACCGGCGCACCTGCTCGTTGCGCTGCTGGAGCAGGAAGATTCCATTGCCCTGCCAGTGCTGCAGGCCGCAG
GCGTGGAGCCGCAGACAATCGCGGCTAAGGCCAAGAACCTGGTCGCCGGATACCCGCAGGCCACCGGTAGCGAGATGGCA
AACCCGCAGTTCAACCGCGACGCGCTGAACGCGCTGACCGCCGCCCAGGAGCTGGCAGAACAGCTGGGTGATACTTATGT
TTCCACCGAGGTTCTGCTGGCCGGTATCGCCAAGGGCAACTCCGACGCTGCCAAGGTGATGCACGAGGCAGGCGCCACCT
TCGAGGCTATCCGCGGTGCCTTCGAATCCGTTCGCGGCAACCGAAAGGTCACCACCGAGGAGCCGGAAGGCCAGTTCCAG
GCGCTGGAGAAGTACTCCACAGACCTGACCGCACGCGCCCGCGAAGGCAAGATTGACCCAGTGATCGGACGTGACCAGGA
GATCCGGCGAGTCGTCCAGGTGCTCTCCCGTCGCACGAAGAACAACCCTGTGCTCATTGGCGAGCCTGGCGTCGGTAAAA
CCGCAATCGTCGAAGGCCTGGCCCGCCGCATTGTCGCTGGCGATGTGCCCGAGTCCCTGCGCGGCAAGAAGCTAATCAGC
CTGGACCTGGGCTCCATGGTCGCCGGCGCGAAATACCGCGGCGAATTTGAGGAGCGGCTGAAGGCTGTGCTGGACGAGAT
TAAGGAGGCCGAGGGCGAAGTAGTTACCTTCATCGACGAGCTGCACACCATCGTCGGTGCCGGTGCGGGCGGCGATTCCG
CCATGGACGCCGGCAACATGATCAAGCCGCTACTGGCCCGCGGCGAACTGCGGCTGGTCGGCGCGACCACTCTGGACGAG
TACCGCAAGTACATCGAAAAGGATGCCGCGCTGGAGCGCCGCTTCCAGCAGGTTTATGTCGGCGAGCCGACGGCGGAGGA
CACCATCGGTATTCTGCGTGGCCTGAAGGAGCGCTACGAGGTGCACCACGGCGTGCGCATCCAGGACTCCGCGCTGGTGG
CGGCCGCGACCTTGTCGGATCGTTACATCACCAGCCGCTTCCTGCCAGATAAGGCCATCGACCTGGTGGACGAGGCTGCT
TCTAGGCTGCGCATGGAGATCGACTCGCGCCCCGAGGAGATCGACAACGTGGAGCGCGTCGTCCGCCGCCTCGAGATTGA
GGAGATGGCGCTGGAGAAGGAGACCGACGCTGCCTCGAAGGACCGTCTGGAACGCCTGCGCAGCGAGCTGGCCGACGAGA
AGGAGAAGCTGGCCGGCCTGACCGCCCGCTGGGAAAACGAGAAGGGCAGTATCGACAGCCTGCGCGAGCTGAAGGAGGAG
CTGGATAACCTGCGCCGCGAATCCGAGATCGCCGAGCGCGAGGGCGACTTCGCCAAGGTCGCCGAGCTGCGCTACGGACA
CATCCCGGACGTGGAGAAGAAGCTGGCCGAGGCGGAGGAGACTGTGGCCGAGCAGCAGGAAGGCATGATGCTGACCGAGG
AGGTCACGCCGGATACTATCGCCGACGTGGTTTCCGCCTGGACCGGCGTGCCCGCGGGCAAGATGCTGCAGGGCGAGACC
GAGAAGCTGTTGAACATGGAGCTCGTGTTGGGCGGTCGCGTGGTTGGCCAGCACCGTGCGGTCGATGCCGTTTCGGATGC
GGTGCGGCGTGCGCGTGCTGGCGTGGCGGACCCGAACCGCCCGACTGGTTCCTTCCTGTTCCTAGGCCCGACGGGCGTGG
GTAAGACGGAGCTAGCGAAGGCTCTGGCTGACTTCCTCTTCGATGACGAGACCGCCATGGTGCGCATCGACATGTCGGAG
TACGGCGAGAAGCACTCCGTCGCTCGCTTGGTCGGTGCCCCTCCGGGATACGTCGGCTATGACGCTGGTGGCCAGCTGAC
CGAGGCCGTGCGGCGCCGCCCCTACACGGTGGTGCTGTTCGACGAGGTGGAAAAGGCTCACCCGGACGTGTTCGACGTGC
TGCTGCAGGTGCTGGACGAGGGTCGCCTGACCGATGGCCAGGGCCGGACCGTGGACTTCCGCAACACGATCCTGATCCTG
ACTTCTAACCTCGGCGCCGGCGGTACCGACGAGGAAGTCATGGAGGCGGTGAAGCGCGCCTTCAAGCCGGAATTCATCAA
CCGACTGGACGACGTGCTGATCTTCGATCCGCTGTCTGCCGAGCAGCTGAAGTCCATCGTGTCTATCCAGGTGGGCACTC
TGGCGGAGCGACTGGCGGCCCGTCGTTTGATCCTGGATGTTACTGATGACGCCCAGTCGTGGCTGGCCGAGCATGGCTAC
GATCCTGCCTACGGTGCCCGGCCGCTACGCCGCCTGATCCAGAAGGCAATCGGCGACCAGCTGGCTAAGAAGCTACTGGC
CGGCGAGGTGCGCGATGGTGACACGGTGCGCGTGGACATTGACCGCAGCGGTGGCGCTGGCGCTGGCGCTGACAGTGCTG
GCGTGGCTGATGCTCCGGGGCTGGTCATCACCTCCCTCGGTGCCGTCGAAGATGAGGACTAA

Upstream 100 bases:

>100_bases
GAATAGACTCAAGGTTGTAGTGGTTGAGTCAGGTGTACTCAAGTAAAGTCGGGCGCGTGCAACCGCGACCGGCATGAAGC
CGTAGGAGGTAGATGTAGAA

Downstream 100 bases:

>100_bases
TGTCTGACGGCTCTGACGGTTAAAAGCTTCTCCGAGCGGCATGAACGCCCCACCTGTTCCGGGTGGGGCGTTTTGGTCTG
CTTTGAGTGGGTGCTAGGGC

Product: ATP-dependent Clp protease, ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 873; Mature: 872

Protein sequence:

>873_residues
MTSFNPTTMTQSAMQAALQDASAKGNPDIRPAHLLVALLEQEDSIALPVLQAAGVEPQTIAAKAKNLVAGYPQATGSEMA
NPQFNRDALNALTAAQELAEQLGDTYVSTEVLLAGIAKGNSDAAKVMHEAGATFEAIRGAFESVRGNRKVTTEEPEGQFQ
ALEKYSTDLTARAREGKIDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLRGKKLIS
LDLGSMVAGAKYRGEFEERLKAVLDEIKEAEGEVVTFIDELHTIVGAGAGGDSAMDAGNMIKPLLARGELRLVGATTLDE
YRKYIEKDAALERRFQQVYVGEPTAEDTIGILRGLKERYEVHHGVRIQDSALVAAATLSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSRPEEIDNVERVVRRLEIEEMALEKETDAASKDRLERLRSELADEKEKLAGLTARWENEKGSIDSLRELKEE
LDNLRRESEIAEREGDFAKVAELRYGHIPDVEKKLAEAEETVAEQQEGMMLTEEVTPDTIADVVSAWTGVPAGKMLQGET
EKLLNMELVLGGRVVGQHRAVDAVSDAVRRARAGVADPNRPTGSFLFLGPTGVGKTELAKALADFLFDDETAMVRIDMSE
YGEKHSVARLVGAPPGYVGYDAGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDVLLQVLDEGRLTDGQGRTVDFRNTILIL
TSNLGAGGTDEEVMEAVKRAFKPEFINRLDDVLIFDPLSAEQLKSIVSIQVGTLAERLAARRLILDVTDDAQSWLAEHGY
DPAYGARPLRRLIQKAIGDQLAKKLLAGEVRDGDTVRVDIDRSGGAGAGADSAGVADAPGLVITSLGAVEDED

Sequences:

>Translated_873_residues
MTSFNPTTMTQSAMQAALQDASAKGNPDIRPAHLLVALLEQEDSIALPVLQAAGVEPQTIAAKAKNLVAGYPQATGSEMA
NPQFNRDALNALTAAQELAEQLGDTYVSTEVLLAGIAKGNSDAAKVMHEAGATFEAIRGAFESVRGNRKVTTEEPEGQFQ
ALEKYSTDLTARAREGKIDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLRGKKLIS
LDLGSMVAGAKYRGEFEERLKAVLDEIKEAEGEVVTFIDELHTIVGAGAGGDSAMDAGNMIKPLLARGELRLVGATTLDE
YRKYIEKDAALERRFQQVYVGEPTAEDTIGILRGLKERYEVHHGVRIQDSALVAAATLSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSRPEEIDNVERVVRRLEIEEMALEKETDAASKDRLERLRSELADEKEKLAGLTARWENEKGSIDSLRELKEE
LDNLRRESEIAEREGDFAKVAELRYGHIPDVEKKLAEAEETVAEQQEGMMLTEEVTPDTIADVVSAWTGVPAGKMLQGET
EKLLNMELVLGGRVVGQHRAVDAVSDAVRRARAGVADPNRPTGSFLFLGPTGVGKTELAKALADFLFDDETAMVRIDMSE
YGEKHSVARLVGAPPGYVGYDAGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDVLLQVLDEGRLTDGQGRTVDFRNTILIL
TSNLGAGGTDEEVMEAVKRAFKPEFINRLDDVLIFDPLSAEQLKSIVSIQVGTLAERLAARRLILDVTDDAQSWLAEHGY
DPAYGARPLRRLIQKAIGDQLAKKLLAGEVRDGDTVRVDIDRSGGAGAGADSAGVADAPGLVITSLGAVEDED
>Mature_872_residues
TSFNPTTMTQSAMQAALQDASAKGNPDIRPAHLLVALLEQEDSIALPVLQAAGVEPQTIAAKAKNLVAGYPQATGSEMAN
PQFNRDALNALTAAQELAEQLGDTYVSTEVLLAGIAKGNSDAAKVMHEAGATFEAIRGAFESVRGNRKVTTEEPEGQFQA
LEKYSTDLTARAREGKIDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLRGKKLISL
DLGSMVAGAKYRGEFEERLKAVLDEIKEAEGEVVTFIDELHTIVGAGAGGDSAMDAGNMIKPLLARGELRLVGATTLDEY
RKYIEKDAALERRFQQVYVGEPTAEDTIGILRGLKERYEVHHGVRIQDSALVAAATLSDRYITSRFLPDKAIDLVDEAAS
RLRMEIDSRPEEIDNVERVVRRLEIEEMALEKETDAASKDRLERLRSELADEKEKLAGLTARWENEKGSIDSLRELKEEL
DNLRRESEIAEREGDFAKVAELRYGHIPDVEKKLAEAEETVAEQQEGMMLTEEVTPDTIADVVSAWTGVPAGKMLQGETE
KLLNMELVLGGRVVGQHRAVDAVSDAVRRARAGVADPNRPTGSFLFLGPTGVGKTELAKALADFLFDDETAMVRIDMSEY
GEKHSVARLVGAPPGYVGYDAGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDVLLQVLDEGRLTDGQGRTVDFRNTILILT
SNLGAGGTDEEVMEAVKRAFKPEFINRLDDVLIFDPLSAEQLKSIVSIQVGTLAERLAARRLILDVTDDAQSWLAEHGYD
PAYGARPLRRLIQKAIGDQLAKKLLAGEVRDGDTVRVDIDRSGGAGAGADSAGVADAPGLVITSLGAVEDED

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=319, Percent_Identity=33.5423197492163, Blast_Score=196, Evalue=1e-49,
Organism=Escherichia coli, GI1788943, Length=846, Percent_Identity=55.2009456264775, Blast_Score=924, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=299, Percent_Identity=48.1605351170569, Blast_Score=281, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6320464, Length=703, Percent_Identity=55.7610241820768, Blast_Score=791, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=865, Percent_Identity=43.6994219653179, Blast_Score=691, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 94826; Mature: 94695

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFNPTTMTQSAMQAALQDASAKGNPDIRPAHLLVALLEQEDSIALPVLQAAGVEPQTI
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCHHHH
AAKAKNLVAGYPQATGSEMANPQFNRDALNALTAAQELAEQLGDTYVSTEVLLAGIAKGN
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
SDAAKVMHEAGATFEAIRGAFESVRGNRKVTTEEPEGQFQALEKYSTDLTARAREGKIDP
CHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCC
VIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLRGKKLIS
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEE
LDLGSMVAGAKYRGEFEERLKAVLDEIKEAEGEVVTFIDELHTIVGAGAGGDSAMDAGNM
EEHHHHHHCCHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHCCCHH
IKPLLARGELRLVGATTLDEYRKYIEKDAALERRFQQVYVGEPTAEDTIGILRGLKERYE
HHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VHHGVRIQDSALVAAATLSDRYITSRFLPDKAIDLVDEAASRLRMEIDSRPEEIDNVERV
HHCCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VRRLEIEEMALEKETDAASKDRLERLRSELADEKEKLAGLTARWENEKGSIDSLRELKEE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHH
LDNLRRESEIAEREGDFAKVAELRYGHIPDVEKKLAEAEETVAEQQEGMMLTEEVTPDTI
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCHHHH
ADVVSAWTGVPAGKMLQGETEKLLNMELVLGGRVVGQHRAVDAVSDAVRRARAGVADPNR
HHHHHHHCCCCCCCCCCCCHHHHHHHHHEECCEECCHHHHHHHHHHHHHHHHCCCCCCCC
PTGSFLFLGPTGVGKTELAKALADFLFDDETAMVRIDMSEYGEKHSVARLVGAPPGYVGY
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHCCCHHHHHHHHCCCCCCCCC
DAGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDVLLQVLDEGRLTDGQGRTVDFRNTILIL
CCCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEE
TSNLGAGGTDEEVMEAVKRAFKPEFINRLDDVLIFDPLSAEQLKSIVSIQVGTLAERLAA
EECCCCCCCCHHHHHHHHHHCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RRLILDVTDDAQSWLAEHGYDPAYGARPLRRLIQKAIGDQLAKKLLAGEVRDGDTVRVDI
HHHHEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DRSGGAGAGADSAGVADAPGLVITSLGAVEDED
ECCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
TSFNPTTMTQSAMQAALQDASAKGNPDIRPAHLLVALLEQEDSIALPVLQAAGVEPQTI
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCHHHH
AAKAKNLVAGYPQATGSEMANPQFNRDALNALTAAQELAEQLGDTYVSTEVLLAGIAKGN
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
SDAAKVMHEAGATFEAIRGAFESVRGNRKVTTEEPEGQFQALEKYSTDLTARAREGKIDP
CHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCC
VIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLRGKKLIS
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEE
LDLGSMVAGAKYRGEFEERLKAVLDEIKEAEGEVVTFIDELHTIVGAGAGGDSAMDAGNM
EEHHHHHHCCHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHCCCHH
IKPLLARGELRLVGATTLDEYRKYIEKDAALERRFQQVYVGEPTAEDTIGILRGLKERYE
HHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VHHGVRIQDSALVAAATLSDRYITSRFLPDKAIDLVDEAASRLRMEIDSRPEEIDNVERV
HHCCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VRRLEIEEMALEKETDAASKDRLERLRSELADEKEKLAGLTARWENEKGSIDSLRELKEE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHH
LDNLRRESEIAEREGDFAKVAELRYGHIPDVEKKLAEAEETVAEQQEGMMLTEEVTPDTI
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCHHHH
ADVVSAWTGVPAGKMLQGETEKLLNMELVLGGRVVGQHRAVDAVSDAVRRARAGVADPNR
HHHHHHHCCCCCCCCCCCCHHHHHHHHHEECCEECCHHHHHHHHHHHHHHHHCCCCCCCC
PTGSFLFLGPTGVGKTELAKALADFLFDDETAMVRIDMSEYGEKHSVARLVGAPPGYVGY
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHCCCHHHHHHHHCCCCCCCCC
DAGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDVLLQVLDEGRLTDGQGRTVDFRNTILIL
CCCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEE
TSNLGAGGTDEEVMEAVKRAFKPEFINRLDDVLIFDPLSAEQLKSIVSIQVGTLAERLAA
EECCCCCCCCHHHHHHHHHHCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RRLILDVTDDAQSWLAEHGYDPAYGARPLRRLIQKAIGDQLAKKLLAGEVRDGDTVRVDI
HHHHEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DRSGGAGAGADSAGVADAPGLVITSLGAVEDED
ECCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]