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The map label for this gene is cmtB [H]

Identifier: 68535198

GI number: 68535198

Start: 156106

End: 157119

Strand: Direct

Name: cmtB [H]

Synonym: jk0133

Alternate gene names: 68535198

Gene position: 156106-157119 (Clockwise)

Preceding gene: 68535197

Following gene: 68535199

Centisome position: 6.34

GC content: 62.72

Gene sequence:

>1014_bases
ATGAACACGACTATGAAGACCAAGGGTCTGGGCTCCAAGCTCACCGCTTTCCTGGTTGCAGTCGCTACTGCGCTGGGTAT
GGCTGTTGTCACTGCGCCCACTGCTTCTGCTGACAACCGTGGCCACCTGCGCCCGGGCTGCAGCTGGAGCAAGCACAAGT
ACTACCTGCAGAACTGCTGGGTCTACTCCCCGGCAATGGGGCAGAAGATCCAGGTGCAGATCAAGCCATCTTCCCGTGGT
GGTAACGCTGGCGTCTACATGCTGGACGGCCTGCGTGCACGCCAGGACTGGAACGCATGGGTCTGGTCGGGCAACGCTGT
AAAGAAGTTCGTTAACGACGACGTGACCCTGGTCATGCCGGTCGGCGGGCAGGCTCAGTTCTACACGGACTGGATGGGCC
CGTACGGCGGTAAGGGTGGCCCGAAGAAGCCGCGTTGGGAGACCTTCCTGACCCGCGAGCTGCCGGGCTACCTGCAGCGC
AACTTCGGCGTGAGCCCGACCCGCAACTCCATTGTTGGTCTTTCTATGGGCGGTACTGCCGCAATGAACCTGGCTGCGTG
GCACCGCAACCAGTTCAAGCAGGCAACCTCCCTGTCCGGTTACCTGAACCCGACCTGGCCGGGCATGTACGCCGGAATCC
AGTACGCGATGTCTGACGCGGACCGGGGTGCAAACATCTGGGACATGTGGGGTAGCCCGGTTGACCCGCGTCGCTTCCGC
AACGACCCGACCGTACAGGCTGGCCGATTCAACGGTATGCCTCTGTACCTGGCTGCCTCTGGCGGCGTCCCGTCTCGCGG
CGAGAAGTTCCTGGATAATCCGCGAGGAGTTGCTGCTGGCATCGGCCTGGAGTGGATGGCACGCACCTCCACTGCGAAGT
TCGAGATGGCTGCCCGTGCAGCCGGAGCTCGACCTGTTGTGAGCTACCCGATCAACGGTCTGCACGCATGGCCGTACTGG
GACGCGGAGCTGAACAAGGCTCGCCCGCACATCCTGCGTGCGCTGGGTGCTTAG

Upstream 100 bases:

>100_bases
GTGCGATCGTAAAGATTTGGTAACGTACACGCATCCTGTGTTTCGAGGCGCGTCTTCGGGACGCCTCTTGTCATATACGT
TTCAAGACATTTAGGACTAC

Downstream 100 bases:

>100_bases
CCTGAGATCGCTTTAGTTTTGAACTGAAGTCACTAAAGCCGCTAAAGCCACTGCCTTGGCTCTTTGCCTAGGGCAGTGGT
TTTTTGTGTGCTCAAGACGT

Product: trehalose corynomycolyl transferase B

Products: NA

Alternate protein names: Antigen 85 complex C; 85C; Ag85C; Fibronectin-binding protein C; Mycolyl transferase 85C [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNTTMKTKGLGSKLTAFLVAVATALGMAVVTAPTASADNRGHLRPGCSWSKHKYYLQNCWVYSPAMGQKIQVQIKPSSRG
GNAGVYMLDGLRARQDWNAWVWSGNAVKKFVNDDVTLVMPVGGQAQFYTDWMGPYGGKGGPKKPRWETFLTRELPGYLQR
NFGVSPTRNSIVGLSMGGTAAMNLAAWHRNQFKQATSLSGYLNPTWPGMYAGIQYAMSDADRGANIWDMWGSPVDPRRFR
NDPTVQAGRFNGMPLYLAASGGVPSRGEKFLDNPRGVAAGIGLEWMARTSTAKFEMAARAAGARPVVSYPINGLHAWPYW
DAELNKARPHILRALGA

Sequences:

>Translated_337_residues
MNTTMKTKGLGSKLTAFLVAVATALGMAVVTAPTASADNRGHLRPGCSWSKHKYYLQNCWVYSPAMGQKIQVQIKPSSRG
GNAGVYMLDGLRARQDWNAWVWSGNAVKKFVNDDVTLVMPVGGQAQFYTDWMGPYGGKGGPKKPRWETFLTRELPGYLQR
NFGVSPTRNSIVGLSMGGTAAMNLAAWHRNQFKQATSLSGYLNPTWPGMYAGIQYAMSDADRGANIWDMWGSPVDPRRFR
NDPTVQAGRFNGMPLYLAASGGVPSRGEKFLDNPRGVAAGIGLEWMARTSTAKFEMAARAAGARPVVSYPINGLHAWPYW
DAELNKARPHILRALGA
>Mature_337_residues
MNTTMKTKGLGSKLTAFLVAVATALGMAVVTAPTASADNRGHLRPGCSWSKHKYYLQNCWVYSPAMGQKIQVQIKPSSRG
GNAGVYMLDGLRARQDWNAWVWSGNAVKKFVNDDVTLVMPVGGQAQFYTDWMGPYGGKGGPKKPRWETFLTRELPGYLQR
NFGVSPTRNSIVGLSMGGTAAMNLAAWHRNQFKQATSLSGYLNPTWPGMYAGIQYAMSDADRGANIWDMWGSPVDPRRFR
NDPTVQAGRFNGMPLYLAASGGVPSRGEKFLDNPRGVAAGIGLEWMARTSTAKFEMAARAAGARPVVSYPINGLHAWPYW
DAELNKARPHILRALGA

Specific function: Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintain

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial A85 antigen family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 36809; Mature: 36809

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTMKTKGLGSKLTAFLVAVATALGMAVVTAPTASADNRGHLRPGCSWSKHKYYLQNCW
CCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCEEEEHHEE
VYSPAMGQKIQVQIKPSSRGGNAGVYMLDGLRARQDWNAWVWSGNAVKKFVNDDVTLVMP
EECCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCEEEEECHHHHHHHCCCEEEEEE
VGGQAQFYTDWMGPYGGKGGPKKPRWETFLTRELPGYLQRNFGVSPTRNSIVGLSMGGTA
CCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHCCCCCCCCCCEEEEECCCHH
AMNLAAWHRNQFKQATSLSGYLNPTWPGMYAGIQYAMSDADRGANIWDMWGSPVDPRRFR
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHCC
NDPTVQAGRFNGMPLYLAASGGVPSRGEKFLDNPRGVAAGIGLEWMARTSTAKFEMAARA
CCCCEECCCCCCEEEEEEECCCCCCCCHHHHCCCCCEEECCCCEEEECCCCHHHHHHHHH
AGARPVVSYPINGLHAWPYWDAELNKARPHILRALGA
CCCCCEEECCCCCEEECCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNTTMKTKGLGSKLTAFLVAVATALGMAVVTAPTASADNRGHLRPGCSWSKHKYYLQNCW
CCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCEEEEHHEE
VYSPAMGQKIQVQIKPSSRGGNAGVYMLDGLRARQDWNAWVWSGNAVKKFVNDDVTLVMP
EECCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCEEEEECHHHHHHHCCCEEEEEE
VGGQAQFYTDWMGPYGGKGGPKKPRWETFLTRELPGYLQRNFGVSPTRNSIVGLSMGGTA
CCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHCCCCCCCCCCEEEEECCCHH
AMNLAAWHRNQFKQATSLSGYLNPTWPGMYAGIQYAMSDADRGANIWDMWGSPVDPRRFR
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHCC
NDPTVQAGRFNGMPLYLAASGGVPSRGEKFLDNPRGVAAGIGLEWMARTSTAKFEMAARA
CCCCEECCCCCCEEEEEEECCCCCCCCHHHHCCCCCEEECCCCEEEECCCCHHHHHHHHH
AGARPVVSYPINGLHAWPYWDAELNKARPHILRALGA
CCCCCEEECCCCCEEECCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8359887; 11234002 [H]