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The map label for this gene is qacA [H]

Identifier: 68535162

GI number: 68535162

Start: 118543

End: 119697

Strand: Direct

Name: qacA [H]

Synonym: jk0097

Alternate gene names: 68535162

Gene position: 118543-119697 (Clockwise)

Preceding gene: 68535161

Following gene: 68535164

Centisome position: 4.81

GC content: 57.4

Gene sequence:

>1155_bases
ATGATGCCGTCTACGTTGTCGCTCATTCGGCTTACATTTTTAGATCCGGCAGAGCTAAACCTCGCAATCGGCATCTGGGG
TAGTCTTTCAACCGTTTCCGCCGCTCTCGGACCTATCGCCGGCGGATTGCTTTTGGAACTGTATTGGTGGGGATCCTGTT
TCCTGATCAACGTTCCCCTTGTTATCGCAGCGCTGATCGCTGTGCCTTTCGTCGCTCCGAAGGATCAGCCGCAACGGGAT
AAGCACTGGGACTTTATCTCTTCTTTCTACGCAATGGTCACCCTGGTAAGCGCAGTGATGCTCATCAAGGAGGGCAGTCA
CTCCCCGCAGAATTGGCCAGTTATTGGCATAGCAGCCATTACGCTCATCCTCGGCGGTTGGGCCTTTACTCGGCGTCAAA
ACAAACTAGACCAGCCGTTGATCACCCTTGACATCTTTCGATTCCCTGCGTTTCGCGCCGGCGCGTTGGGAGCAGCGCTT
TCCATGTTTGCTCTTGCTGGCCTGCAGTACGTCATTACACAAAAACTGCAGCTTGCCGACGGCTTATCGCCGCTGCGCTC
CGGCGTCTACGTGACATTCGCGGCCATTGGGGCCCTTTTCTCGTCTATTTATGCCGGTGCTCGTTTAGCGCGCTTCGGAA
TCAGGCGACTGATCGCTGGCGGCTTCGGACTAGCCACCATCGGTGCGGTGATTGTGTGTCTTTATGGTCTTTGGGAGTCG
ACGCCCCTACTGCTCGGCGGCCTGTTTATTAAGGGTATGGGGTTGGGCGCGGTGGTGGCGGTAGCCTCTATCGCCATGAT
CTCTGGCGTACCCAGCCATCGTGCAGGCATGGCCTCCTCAGTGGAGGAAGTCAGCTACGAATTCGGCTCCCTGACGTCCA
TTGCTGTTCTCGGTAGCTTGGTGACGGCCTTCTATTCGGCACTGATTACTCTGCCAACCGGTGCTCCCGAGGAGGCTGCG
GACAGCTTGCACGCCGCCGTGCATCTTGCGCATTCTTCAGACGCCAGCTGGGCGGAACCGCTGATAGCTGCCGCAGACAC
GGCCTATTCCCATGCCTTCGCGCTGATTACAGTCTTGGTCGTGGTGGTTTTGGCGGCCGGCTGCCTCTACACAGCCCGTA
TCCTGCGGGGCGTAACTGTGGAGCTGCAGGACTGA

Upstream 100 bases:

>100_bases
GCTTGTCATTTTCGGAATTGCTTCGTTCGTAGCAGCTTTCGCCCCTACCCCCGGGATTCTTATTCTCGGCCGCGCCTTGT
TAGCAGTAGGTGGCGCTACG

Downstream 100 bases:

>100_bases
TCTCGCAGATGGCTAGAAGCGGCTGACGAACTTCCGCTCCTGGCCACTCAAAGGGTCGGGGAAGCGGAGCTCCTTGGCGA
TAAGCCCCATTGGGGAGGAA

Product: major facilitator superfamily permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MMPSTLSLIRLTFLDPAELNLAIGIWGSLSTVSAALGPIAGGLLLELYWWGSCFLINVPLVIAALIAVPFVAPKDQPQRD
KHWDFISSFYAMVTLVSAVMLIKEGSHSPQNWPVIGIAAITLILGGWAFTRRQNKLDQPLITLDIFRFPAFRAGALGAAL
SMFALAGLQYVITQKLQLADGLSPLRSGVYVTFAAIGALFSSIYAGARLARFGIRRLIAGGFGLATIGAVIVCLYGLWES
TPLLLGGLFIKGMGLGAVVAVASIAMISGVPSHRAGMASSVEEVSYEFGSLTSIAVLGSLVTAFYSALITLPTGAPEEAA
DSLHAAVHLAHSSDASWAEPLIAAADTAYSHAFALITVLVVVVLAAGCLYTARILRGVTVELQD

Sequences:

>Translated_384_residues
MMPSTLSLIRLTFLDPAELNLAIGIWGSLSTVSAALGPIAGGLLLELYWWGSCFLINVPLVIAALIAVPFVAPKDQPQRD
KHWDFISSFYAMVTLVSAVMLIKEGSHSPQNWPVIGIAAITLILGGWAFTRRQNKLDQPLITLDIFRFPAFRAGALGAAL
SMFALAGLQYVITQKLQLADGLSPLRSGVYVTFAAIGALFSSIYAGARLARFGIRRLIAGGFGLATIGAVIVCLYGLWES
TPLLLGGLFIKGMGLGAVVAVASIAMISGVPSHRAGMASSVEEVSYEFGSLTSIAVLGSLVTAFYSALITLPTGAPEEAA
DSLHAAVHLAHSSDASWAEPLIAAADTAYSHAFALITVLVVVVLAAGCLYTARILRGVTVELQD
>Mature_384_residues
MMPSTLSLIRLTFLDPAELNLAIGIWGSLSTVSAALGPIAGGLLLELYWWGSCFLINVPLVIAALIAVPFVAPKDQPQRD
KHWDFISSFYAMVTLVSAVMLIKEGSHSPQNWPVIGIAAITLILGGWAFTRRQNKLDQPLITLDIFRFPAFRAGALGAAL
SMFALAGLQYVITQKLQLADGLSPLRSGVYVTFAAIGALFSSIYAGARLARFGIRRLIAGGFGLATIGAVIVCLYGLWES
TPLLLGGLFIKGMGLGAVVAVASIAMISGVPSHRAGMASSVEEVSYEFGSLTSIAVLGSLVTAFYSALITLPTGAPEEAA
DSLHAAVHLAHSSDASWAEPLIAAADTAYSHAFALITVLVVVVLAAGCLYTARILRGVTVELQD

Specific function: Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes, quaternary ammonium salts and diamidines [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=322, Percent_Identity=26.7080745341615, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40359; Mature: 40359

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPSTLSLIRLTFLDPAELNLAIGIWGSLSTVSAALGPIAGGLLLELYWWGSCFLINVPL
CCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHH
VIAALIAVPFVAPKDQPQRDKHWDFISSFYAMVTLVSAVMLIKEGSHSPQNWPVIGIAAI
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
TLILGGWAFTRRQNKLDQPLITLDIFRFPAFRAGALGAALSMFALAGLQYVITQKLQLAD
HHHHHHHHHHHHHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLSPLRSGVYVTFAAIGALFSSIYAGARLARFGIRRLIAGGFGLATIGAVIVCLYGLWES
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
TPLLLGGLFIKGMGLGAVVAVASIAMISGVPSHRAGMASSVEEVSYEFGSLTSIAVLGSL
CHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VTAFYSALITLPTGAPEEAADSLHAAVHLAHSSDASWAEPLIAAADTAYSHAFALITVLV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVVLAAGCLYTARILRGVTVELQD
HHHHHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MMPSTLSLIRLTFLDPAELNLAIGIWGSLSTVSAALGPIAGGLLLELYWWGSCFLINVPL
CCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHH
VIAALIAVPFVAPKDQPQRDKHWDFISSFYAMVTLVSAVMLIKEGSHSPQNWPVIGIAAI
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
TLILGGWAFTRRQNKLDQPLITLDIFRFPAFRAGALGAALSMFALAGLQYVITQKLQLAD
HHHHHHHHHHHHHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLSPLRSGVYVTFAAIGALFSSIYAGARLARFGIRRLIAGGFGLATIGAVIVCLYGLWES
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
TPLLLGGLFIKGMGLGAVVAVASIAMISGVPSHRAGMASSVEEVSYEFGSLTSIAVLGSL
CHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VTAFYSALITLPTGAPEEAADSLHAAVHLAHSSDASWAEPLIAAADTAYSHAFALITVLV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVVLAAGCLYTARILRGVTVELQD
HHHHHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]