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The map label for this gene is rhtC [H]

Identifier: 68535141

GI number: 68535141

Start: 89937

End: 90578

Strand: Direct

Name: rhtC [H]

Synonym: jk0078

Alternate gene names: 68535141

Gene position: 89937-90578 (Clockwise)

Preceding gene: 68535140

Following gene: 68535142

Centisome position: 3.65

GC content: 63.86

Gene sequence:

>642_bases
GTGCCAGGTCCAGACACCGTGCAGCTCATTCGTTTGGGTGCCCGTTCGCGCCGCTCGGCGGTGTTCGCCGCGCTGGGAAT
CTGCACGGGCAACGTGTTGTGGCCGGTGGTCACGATGCTCGGCCTGGCTGCGCTGATCGCGGCCTTCCCGTGGATCCTGA
CGGTGTTGTACCTGTTCGGTGGCTGTTTCTTGATCTATATGGGCCAAGGCGCGTTCCGCTCGGGATACGCGGATTGGCGC
GCCCGTGCCGTCTTGCCCGCTGTTTCTCTTAGTGACGCCACCCGCGCCCCAACGGCTGCCGGTGGAGTACAGGCTACGGC
GCGCGCACCGTTGGGAGACTTCGCTTCCTGGCGCCTGGGGCTTGCGACGAACCTTTCCAACCCCAAGGCGCTGCTGTTCT
TCGGTTCGGTGTTCGCGCAGTTCATCCCGGTAGAGGCTTCCTTAACAGACCGGCTGCTGGTGCTCGTTTTGATGACTGTC
GTGGGGCTGGCGTGGTTCTGTGGATTCGCCCTGGCGGTGGCCGCGGGAGCGGAAAAGATCCAGCGGATTAACCCCTTCAT
CGAGATGGTGGCCGGGGTGCTATTCGTCGTGCTGGGCGCGTTCCTGGCTTTCGAGGGCGTGCAGATGCTGGTGGGTAGCT
AA

Upstream 100 bases:

>100_bases
CCGCCCTGCCACGCCCGATCAATCCGACTGACGTGGCGATGCAGGCTTGAGCCTAGCCGCTTACCTTGGGCTGCTCGGTG
CCTGGGTGCTGGCCATTACG

Downstream 100 bases:

>100_bases
AGCCCGCTAGACTGAGGCTCATGGAGTTTCCAGAGGTCAGCATTCGCGATTCCGAAATCAAGCTGGGGCAATTCATCAAA
TTGGCGAACCTGGTGGAAAC

Product: hypothetical protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MPGPDTVQLIRLGARSRRSAVFAALGICTGNVLWPVVTMLGLAALIAAFPWILTVLYLFGGCFLIYMGQGAFRSGYADWR
ARAVLPAVSLSDATRAPTAAGGVQATARAPLGDFASWRLGLATNLSNPKALLFFGSVFAQFIPVEASLTDRLLVLVLMTV
VGLAWFCGFALAVAAGAEKIQRINPFIEMVAGVLFVVLGAFLAFEGVQMLVGS

Sequences:

>Translated_213_residues
MPGPDTVQLIRLGARSRRSAVFAALGICTGNVLWPVVTMLGLAALIAAFPWILTVLYLFGGCFLIYMGQGAFRSGYADWR
ARAVLPAVSLSDATRAPTAAGGVQATARAPLGDFASWRLGLATNLSNPKALLFFGSVFAQFIPVEASLTDRLLVLVLMTV
VGLAWFCGFALAVAAGAEKIQRINPFIEMVAGVLFVVLGAFLAFEGVQMLVGS
>Mature_212_residues
PGPDTVQLIRLGARSRRSAVFAALGICTGNVLWPVVTMLGLAALIAAFPWILTVLYLFGGCFLIYMGQGAFRSGYADWRA
RAVLPAVSLSDATRAPTAAGGVQATARAPLGDFASWRLGLATNLSNPKALLFFGSVFAQFIPVEASLTDRLLVLVLMTVV
GLAWFCGFALAVAAGAEKIQRINPFIEMVAGVLFVVLGAFLAFEGVQMLVGS

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=204, Percent_Identity=31.8627450980392, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22457; Mature: 22326

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGPDTVQLIRLGARSRRSAVFAALGICTGNVLWPVVTMLGLAALIAAFPWILTVLYLFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCFLIYMGQGAFRSGYADWRARAVLPAVSLSDATRAPTAAGGVQATARAPLGDFASWRLG
HHHHHHCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHH
LATNLSNPKALLFFGSVFAQFIPVEASLTDRLLVLVLMTVVGLAWFCGFALAVAAGAEKI
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRINPFIEMVAGVLFVVLGAFLAFEGVQMLVGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGPDTVQLIRLGARSRRSAVFAALGICTGNVLWPVVTMLGLAALIAAFPWILTVLYLFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCFLIYMGQGAFRSGYADWRARAVLPAVSLSDATRAPTAAGGVQATARAPLGDFASWRLG
HHHHHHCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHH
LATNLSNPKALLFFGSVFAQFIPVEASLTDRLLVLVLMTVVGLAWFCGFALAVAAGAEKI
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRINPFIEMVAGVLFVVLGAFLAFEGVQMLVGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]