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The map label for this gene is utp1 [C]

Identifier: 68535079

GI number: 68535079

Start: 23416

End: 23805

Strand: Direct

Name: utp1 [C]

Synonym: jk0017

Alternate gene names: 68535079

Gene position: 23416-23805 (Clockwise)

Preceding gene: 68535078

Following gene: 68535080

Centisome position: 0.95

GC content: 66.92

Gene sequence:

>390_bases
ATGATTGAAGTAGCAGCCGTCGTCATCCGCAACCCACAAGGCCACGTGCTTACCGTGCGCAAGAAGTCCTCCACCAAGTA
CCAACTGCCCGGCGGCAAGCCCGAGGCGGGCGAGGCGCTTGTCGACGCCGCCCTGCGCGAAGTTGCCGAAGAAGTAGGCC
TCACCCTCGACGCCGAGAGCCTCAACAAACTCGGCACCTTCGACGCTCCCGCCGCCAACGAACCGGGCGAGGTCGTCGTC
GGCACCATCTTCACCTACACCCGCACCGTCACCGCCGACGAACCCCATGCCGCCGCCGAAATCGGCGACACCGCCTGGGT
CAACCCAGCAGCCCCCGACCGCGAGCTTGCACACCTGCTGCGCGACCGCGTCTTCCCCACGCTGGCCTAG

Upstream 100 bases:

>100_bases
GGTCTATGGCCGTGGGCTGGACGCTTGCCGCGCTGGTCATCGCACTCAATCTCGCCCTCGTGCTCCTGCCGCTGCTCTAG
GCCGCCTACAATCAGCAGCC

Downstream 100 bases:

>100_bases
CGCCAACTGTCAACACTTCGGCGTCATTGACCTCGAAACCATCAAGAGCTACCCTTTTGAACATGTTCACTGAACACGTT
CACTCATCGCGCTCGGCCGC

Product: NUDIX protein

Products: 8-Oxo-Dgmp; Pyrophosphate. [C]

Alternate protein names: MutT/Nudix Family Protein; MutT/NUDIX Family Protein; Phosphohydrolase; NTP Pyrophosphohydrolase; MutT Family NTP Pyrophosphatase; NUDIX Protein; NUDIX Family Protein; Phosphatase; NUDIX Family Hydrolase; ADP-Ribose Pyrophosphatase; MutT/Nudix Family Hydrolase; Uridine Kinase; MutT/Nudix Family Phosphohydrolase; NTP Pyrophosphohydrolase Including Oxidative Damage Repair; Hydrolase Nudix Family; Hydrolase Nudix Family Protein; Hydrolase NUDIX Family

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MIEVAAVVIRNPQGHVLTVRKKSSTKYQLPGGKPEAGEALVDAALREVAEEVGLTLDAESLNKLGTFDAPAANEPGEVVV
GTIFTYTRTVTADEPHAAAEIGDTAWVNPAAPDRELAHLLRDRVFPTLA

Sequences:

>Translated_129_residues
MIEVAAVVIRNPQGHVLTVRKKSSTKYQLPGGKPEAGEALVDAALREVAEEVGLTLDAESLNKLGTFDAPAANEPGEVVV
GTIFTYTRTVTADEPHAAAEIGDTAWVNPAAPDRELAHLLRDRVFPTLA
>Mature_129_residues
MIEVAAVVIRNPQGHVLTVRKKSSTKYQLPGGKPEAGEALVDAALREVAEEVGLTLDAESLNKLGTFDAPAANEPGEVVV
GTIFTYTRTVTADEPHAAAEIGDTAWVNPAAPDRELAHLLRDRVFPTLA

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 13698; Mature: 13698

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVAAVVIRNPQGHVLTVRKKSSTKYQLPGGKPEAGEALVDAALREVAEEVGLTLDAES
CCEEEEEEEECCCCCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCEECHHH
LNKLGTFDAPAANEPGEVVVGTIFTYTRTVTADEPHAAAEIGDTAWVNPAAPDRELAHLL
HHHCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCHHHCCCCCCCCCCCCCHHHHHHH
RDRVFPTLA
HHHCCCCCC
>Mature Secondary Structure
MIEVAAVVIRNPQGHVLTVRKKSSTKYQLPGGKPEAGEALVDAALREVAEEVGLTLDAES
CCEEEEEEEECCCCCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCEECHHH
LNKLGTFDAPAANEPGEVVVGTIFTYTRTVTADEPHAAAEIGDTAWVNPAAPDRELAHLL
HHHCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCHHHCCCCCCCCCCCCCHHHHHHH
RDRVFPTLA
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 8-Oxo-Dgtp; H2O [C]

Specific reaction: 8-Oxo-Dgtp + H2O = 8-Oxo-Dgmp + Pyrophosphate. [C]

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA