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The map label for this gene is sdhB [H]

Identifier: 66768306

GI number: 66768306

Start: 2396765

End: 2397547

Strand: Direct

Name: sdhB [H]

Synonym: XC_1985

Alternate gene names: 66768306

Gene position: 2396765-2397547 (Clockwise)

Preceding gene: 66768305

Following gene: 66768307

Centisome position: 46.55

GC content: 62.58

Gene sequence:

>783_bases
ATGGCAGAGTTCACCCTCCCCAAGAATTCAAAGATCGGCAAGGGCAAGCATTACCCTGCACAAGGCGCCAAGAACAAGCG
CACCTTCAAGGTCTACCGTTGGGATCCGGATGGCGACGCCAATCCGCGTACCGACAGCTATGAAATCGATCTGGACAAGT
GCGGACCGATGGTCCTGGACGCGCTGATCAAGATCAAGAACGAGATCGACCCGACCCTGACCTTCCGCCGCTCCTGCCGC
GAAGGCATCTGCGGTTCGTGCGCGATGAACATCGACGGCACCAATACGCTGGCCTGCACCAAGGCGATTGCCGCGTGTGG
CAAGGCCGAGGTGCCGATCTATCCGCTGCCGCACATGAGCGTGATCAAGGATCTGGTGCCGGACCTGACGCATTTCTATG
CGCAGTACGCCTCGATCAAACCGTGGATCCGTACCCAGACCCCGCCGCCGCCGGACCGCGAGCGCCTGCAGTCGCCGGAA
GACCGCAAGAAGCTTGACGGCCTGTACGAGTGCATCCTGTGCGCGTGCTGCTCCACCAGCTGCCCGAGCTACTGGTGGAA
CGGCGAGCGCTACCTGGGCCCGGCGATCCTGCTGCAGGCCTACCGCTGGATCATCGACTCGCGCGATGAAGACACCGGTG
CGCGCCTGGACGATCTGGAGGATCCGTTCAAGCTGTATCGCTGCCACACCATCATGAACTGCGCCCGCACCTGCCCTAAG
GGGCTGAACCCGGCGCTGGCGATCGCCGAGATCAAGAAGCTGATGATGGCGCGCCGCGCCTGA

Upstream 100 bases:

>100_bases
TGCACTTCCGCATCGGTGGTGGCATCCATCGTCTTCAATTTCATGCGCACGCTGCGGTCTCCCATCGCACCGCGCATCGC
CTGAGCCAACGAGAGCAGCT

Downstream 100 bases:

>100_bases
TCCTGGCGCTGATGTCCTGCTCAGGCAGGACGTCACCACAGCGGCACCGGCCCTCAGGTCTGGTGCCGCTGTCGTTTTCG
GCCCGCTACAACGCGGGATG

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAEFTLPKNSKIGKGKHYPAQGAKNKRTFKVYRWDPDGDANPRTDSYEIDLDKCGPMVLDALIKIKNEIDPTLTFRRSCR
EGICGSCAMNIDGTNTLACTKAIAACGKAEVPIYPLPHMSVIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPE
DRKKLDGLYECILCACCSTSCPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPK
GLNPALAIAEIKKLMMARRA

Sequences:

>Translated_260_residues
MAEFTLPKNSKIGKGKHYPAQGAKNKRTFKVYRWDPDGDANPRTDSYEIDLDKCGPMVLDALIKIKNEIDPTLTFRRSCR
EGICGSCAMNIDGTNTLACTKAIAACGKAEVPIYPLPHMSVIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPE
DRKKLDGLYECILCACCSTSCPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPK
GLNPALAIAEIKKLMMARRA
>Mature_259_residues
AEFTLPKNSKIGKGKHYPAQGAKNKRTFKVYRWDPDGDANPRTDSYEIDLDKCGPMVLDALIKIKNEIDPTLTFRRSCRE
GICGSCAMNIDGTNTLACTKAIAACGKAEVPIYPLPHMSVIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPED
RKKLDGLYECILCACCSTSCPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPKG
LNPALAIAEIKKLMMARRA

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=248, Percent_Identity=66.9354838709677, Blast_Score=348, Evalue=2e-96,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=55.3191489361702, Blast_Score=274, Evalue=4e-75,
Organism=Escherichia coli, GI1790596, Length=224, Percent_Identity=33.0357142857143, Blast_Score=129, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17533915, Length=231, Percent_Identity=63.2034632034632, Blast_Score=320, Evalue=5e-88,
Organism=Saccharomyces cerevisiae, GI6322987, Length=228, Percent_Identity=69.2982456140351, Blast_Score=334, Evalue=7e-93,
Organism=Drosophila melanogaster, GI17137106, Length=233, Percent_Identity=66.9527896995708, Blast_Score=343, Evalue=4e-95,
Organism=Drosophila melanogaster, GI24643156, Length=233, Percent_Identity=64.8068669527897, Blast_Score=323, Evalue=8e-89,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29367; Mature: 29236

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFTLPKNSKIGKGKHYPAQGAKNKRTFKVYRWDPDGDANPRTDSYEIDLDKCGPMVLD
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECHHHCCHHHHH
ALIKIKNEIDPTLTFRRSCREGICGSCAMNIDGTNTLACTKAIAACGKAEVPIYPLPHMS
HHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHH
VIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPEDRKKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCC
CPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GLNPALAIAEIKKLMMARRA
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEFTLPKNSKIGKGKHYPAQGAKNKRTFKVYRWDPDGDANPRTDSYEIDLDKCGPMVLD
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECHHHCCHHHHH
ALIKIKNEIDPTLTFRRSCREGICGSCAMNIDGTNTLACTKAIAACGKAEVPIYPLPHMS
HHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHH
VIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPEDRKKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCC
CPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GLNPALAIAEIKKLMMARRA
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA