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The map label for this gene is dsbE [H]

Identifier: 66768213

GI number: 66768213

Start: 2288672

End: 2289274

Strand: Reverse

Name: dsbE [H]

Synonym: XC_1892

Alternate gene names: 66768213

Gene position: 2289274-2288672 (Counterclockwise)

Preceding gene: 66768214

Following gene: 66768212

Centisome position: 44.46

GC content: 68.16

Gene sequence:

>603_bases
ATGTCTGACCCTCGCACCTCCCGCCTGCCCACCGCCGTGCTTGTGGGAGCGGGCATCCTGCTGCTCGCGCTGGCGGCGTT
GCTGGTCTACGCCGTGGTGCGTTCGGGCAATGACGACCGCGACGCCCTGCCGTCGGCACTGATCGGCAAGCCGGCGCCGG
AGTTCGCGCTGCCGTTGCTGCACGATCCCAGCATCATCGTGCATGCGCGCGAACTGCGCGGTGCGCCCTACATCATCAAC
GTGTGGGGCAGCTGGTGCCCGGCCTGCCGCGAAGAACATCCGGTGCTGAGCCGCTTCGCACTGACCAAGCGCGTGCGCGT
GATCGGCTACAACTGGAAGGACGAGCGCGCCGATGCCTTGCGCTGGCTCGAACAACTGGGCAACCCGTATCTGCTGGTGG
TCGCCGACACCGATGGCCGCACCGCGATCGACTTCGGCATTGCCGCCGCACCGGAAACCTTCCTGGTCGACGGCCGCGGC
GTGGTGCGCTGGAAGTACAGCGGCATGCTGACCCAATCCATCATCGACACCCAGCTGATTCCGGCCCTGACCCGCATCGA
GCGCTCGCCCAGCGCCGCGCCGGACCTGCACACCGCCCGATGA

Upstream 100 bases:

>100_bases
CCGTTTGTCCGCTGGATCTGGCTGGGAGCGCTGCTGATGGCGCTCGGCGGCCTGGTCACCGCGGCCGACCGGCGTTTCCG
TCGTTCTCCGGAGTCCCTAA

Downstream 100 bases:

>100_bases
CACGCGCCTGGCTACTCGCATTGTTGCTGTGGCCCTGGCTGGCATTGGCCCAGCCAATGGGCGACCCCTCGCTGCTGCAG
TACCGCTCGGCCGCCGAGGA

Product: c-type cytochrome biogenesis protein/thioredoxin dsbE or

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSDPRTSRLPTAVLVGAGILLLALAALLVYAVVRSGNDDRDALPSALIGKPAPEFALPLLHDPSIIVHARELRGAPYIIN
VWGSWCPACREEHPVLSRFALTKRVRVIGYNWKDERADALRWLEQLGNPYLLVVADTDGRTAIDFGIAAAPETFLVDGRG
VVRWKYSGMLTQSIIDTQLIPALTRIERSPSAAPDLHTAR

Sequences:

>Translated_200_residues
MSDPRTSRLPTAVLVGAGILLLALAALLVYAVVRSGNDDRDALPSALIGKPAPEFALPLLHDPSIIVHARELRGAPYIIN
VWGSWCPACREEHPVLSRFALTKRVRVIGYNWKDERADALRWLEQLGNPYLLVVADTDGRTAIDFGIAAAPETFLVDGRG
VVRWKYSGMLTQSIIDTQLIPALTRIERSPSAAPDLHTAR
>Mature_199_residues
SDPRTSRLPTAVLVGAGILLLALAALLVYAVVRSGNDDRDALPSALIGKPAPEFALPLLHDPSIIVHARELRGAPYIINV
WGSWCPACREEHPVLSRFALTKRVRVIGYNWKDERADALRWLEQLGNPYLLVVADTDGRTAIDFGIAAAPETFLVDGRGV
VRWKYSGMLTQSIIDTQLIPALTRIERSPSAAPDLHTAR

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=173, Percent_Identity=41.0404624277457, Blast_Score=149, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21910; Mature: 21778

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPRTSRLPTAVLVGAGILLLALAALLVYAVVRSGNDDRDALPSALIGKPAPEFALPLL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCCHHCCCCC
HDPSIIVHARELRGAPYIINVWGSWCPACREEHPVLSRFALTKRVRVIGYNWKDERADAL
CCCCEEEEHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHH
RWLEQLGNPYLLVVADTDGRTAIDFGIAAAPETFLVDGRGVVRWKYSGMLTQSIIDTQLI
HHHHHCCCCEEEEEECCCCCEEEECCCCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHH
PALTRIERSPSAAPDLHTAR
HHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SDPRTSRLPTAVLVGAGILLLALAALLVYAVVRSGNDDRDALPSALIGKPAPEFALPLL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCCHHCCCCC
HDPSIIVHARELRGAPYIINVWGSWCPACREEHPVLSRFALTKRVRVIGYNWKDERADAL
CCCCEEEEHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHH
RWLEQLGNPYLLVVADTDGRTAIDFGIAAAPETFLVDGRGVVRWKYSGMLTQSIIDTQLI
HHHHHCCCCEEEEEECCCCCEEEECCCCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHH
PALTRIERSPSAAPDLHTAR
HHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]