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The map label for this gene is aroP [C]

Identifier: 66768177

GI number: 66768177

Start: 2251491

End: 2252855

Strand: Reverse

Name: aroP [C]

Synonym: XC_1856

Alternate gene names: 66768177

Gene position: 2252855-2251491 (Counterclockwise)

Preceding gene: 66768178

Following gene: 66768176

Centisome position: 43.76

GC content: 63.96

Gene sequence:

>1365_bases
ATGTGCGACATGAGCAACGAGCAACTCAAGCCGACCCTGGGCACCTGGCAACTGTGGGGCATTGCAGTCGGGCTAGTGAT
TTCAGGCGAATATTTTGGCTGGAGTTATGGGTGGGGCACGGCCGGCACCTTGGGCTTTCTGGTCACCACGGTGCTGGTGG
CGGTGATGTACACCTGCTTCATTTTCAGTTTCACCGAACTGACCACGGCCATCCCCAATGCGGGCGGCCCGTTCGCCTAC
AGCCTGCGCGCGTTCGGCACCTATGGCGGCATGCTCGCCGGGCTGGCGACCTTGATCGAATTCGTGTTCGCGCCACCGGC
CATTGCCATGGCAATCGGTGCGTATCTCAATGTGCAGTTCCCCACACTGGACCCACGCGTCGCCGCGATCGGGGCGTACG
TGATCTTCATGAGCTTGAACATCGTGGGTGTGGCGATCGCGGCCACGTTCGAGTTGATCGTGACCTTGCTGGCGGTGATC
GAGCTGCTGGTGTTCATGGGCGTGGTGGCGCCGGGTTTCAGCGTGGCGCGCTTTGCAGCCAACGGCTGGGCCGGCAGCAA
TCAGTTCGGGCCGGCGGCGATCTCGGGCATCTTCGCCGCGATCCCGTTTGCGATCTGGTTCTTCCTGGCGATCGAGGGCG
CGGCGATGGCCGCCGAAGAAGCCAAGGACCCGAAACGAACCATTCCACGCGCCTACATCGCCGGCATTCTTACCCTGGTG
GTGCTGGCGCTGGGTGTGATGGTGTTTGCCGGCGGCGTCGGTGACTGGCGCCAGCTGTCCAACATCAACGACCCGCTGCC
GCAGGCAATGAAGGCGGTGGTGGGCAACAGCTCGACGTGGTTGCACATGCTGGTGTGGATTGGCCTGTTCGGCCTGGTGG
CCAGTTTCCACGGCATCATCCTGGGCTATTCGCGGCAGTTCTTCGCGCTGGCACGCGCCGGCTTCCTGCCGCACGGGCTG
GCGAAGTTGTCGCGCTTCCGCACGCCGCACCGGGCCATCCTCGCCGGTGGCGTGATCGGCATTGCGGCCATCTGCAGCGA
CAGCGTGGTGAAGATTCAGGGCATGTCGCTGACCGCGGCCATGATCACCATGTCCGTGTTCGGCGCCATCGTGATGTATG
TGATGAGCATGCTCAGCCTGTTCAAATTACGCCGCACCGAACCCACGCTGGAGCGCAGCTTCCGTGCGCCCGGCTACCCG
GTGGTGCCGGCGATTGCCTTGCTGCTGGCGCTGGTGTGCCTGGTGGCGATGGTCTGGTTCAACCCGCTGGTGGCGTTGGT
CTTCGTCGGCCTGCTGCTGTTCGGTGCGGTGTGTTGCCTGCTGAGCTTGCGTGGCCGCCCCAACGCCGGGGGTATCGCGG
GATGA

Upstream 100 bases:

>100_bases
TTGCCGGTGACAGCGGCCGATCAGCCAGCGACGGTCAGTCCGTGTCGCGGCCCAGTCTGGCAACCGACGCGCTTCGTCTC
CCCTCCCCCGACCGCAGGAG

Downstream 100 bases:

>100_bases
GTGGATTTGCCTTCAGTGCCGGCGGCGAGCGCTTCCGCTTCGCCGATCTGAAGGACCTGCTGGCCAAGGCCACGCCCGCG
CGCTCGGGCGATCAGTTGGC

Product: ethanolamin permease

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MCDMSNEQLKPTLGTWQLWGIAVGLVISGEYFGWSYGWGTAGTLGFLVTTVLVAVMYTCFIFSFTELTTAIPNAGGPFAY
SLRAFGTYGGMLAGLATLIEFVFAPPAIAMAIGAYLNVQFPTLDPRVAAIGAYVIFMSLNIVGVAIAATFELIVTLLAVI
ELLVFMGVVAPGFSVARFAANGWAGSNQFGPAAISGIFAAIPFAIWFFLAIEGAAMAAEEAKDPKRTIPRAYIAGILTLV
VLALGVMVFAGGVGDWRQLSNINDPLPQAMKAVVGNSSTWLHMLVWIGLFGLVASFHGIILGYSRQFFALARAGFLPHGL
AKLSRFRTPHRAILAGGVIGIAAICSDSVVKIQGMSLTAAMITMSVFGAIVMYVMSMLSLFKLRRTEPTLERSFRAPGYP
VVPAIALLLALVCLVAMVWFNPLVALVFVGLLLFGAVCCLLSLRGRPNAGGIAG

Sequences:

>Translated_454_residues
MCDMSNEQLKPTLGTWQLWGIAVGLVISGEYFGWSYGWGTAGTLGFLVTTVLVAVMYTCFIFSFTELTTAIPNAGGPFAY
SLRAFGTYGGMLAGLATLIEFVFAPPAIAMAIGAYLNVQFPTLDPRVAAIGAYVIFMSLNIVGVAIAATFELIVTLLAVI
ELLVFMGVVAPGFSVARFAANGWAGSNQFGPAAISGIFAAIPFAIWFFLAIEGAAMAAEEAKDPKRTIPRAYIAGILTLV
VLALGVMVFAGGVGDWRQLSNINDPLPQAMKAVVGNSSTWLHMLVWIGLFGLVASFHGIILGYSRQFFALARAGFLPHGL
AKLSRFRTPHRAILAGGVIGIAAICSDSVVKIQGMSLTAAMITMSVFGAIVMYVMSMLSLFKLRRTEPTLERSFRAPGYP
VVPAIALLLALVCLVAMVWFNPLVALVFVGLLLFGAVCCLLSLRGRPNAGGIAG
>Mature_454_residues
MCDMSNEQLKPTLGTWQLWGIAVGLVISGEYFGWSYGWGTAGTLGFLVTTVLVAVMYTCFIFSFTELTTAIPNAGGPFAY
SLRAFGTYGGMLAGLATLIEFVFAPPAIAMAIGAYLNVQFPTLDPRVAAIGAYVIFMSLNIVGVAIAATFELIVTLLAVI
ELLVFMGVVAPGFSVARFAANGWAGSNQFGPAAISGIFAAIPFAIWFFLAIEGAAMAAEEAKDPKRTIPRAYIAGILTLV
VLALGVMVFAGGVGDWRQLSNINDPLPQAMKAVVGNSSTWLHMLVWIGLFGLVASFHGIILGYSRQFFALARAGFLPHGL
AKLSRFRTPHRAILAGGVIGIAAICSDSVVKIQGMSLTAAMITMSVFGAIVMYVMSMLSLFKLRRTEPTLERSFRAPGYP
VVPAIALLLALVCLVAMVWFNPLVALVFVGLLLFGAVCCLLSLRGRPNAGGIAG

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1790653, Length=361, Percent_Identity=25.7617728531856, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786789, Length=386, Percent_Identity=19.9481865284974, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786302, Length=432, Percent_Identity=21.0648148148148, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081708, Length=458, Percent_Identity=22.9257641921397, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082250, Length=436, Percent_Identity=22.4770642201835, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786602, Length=442, Percent_Identity=20.5882352941176, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48049; Mature: 48049

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]