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The map label for this gene is cspA [H]

Identifier: 66768149

GI number: 66768149

Start: 2221555

End: 2221764

Strand: Direct

Name: cspA [H]

Synonym: XC_1828

Alternate gene names: 66768149

Gene position: 2221555-2221764 (Clockwise)

Preceding gene: 66768144

Following gene: 66768150

Centisome position: 43.15

GC content: 60.0

Gene sequence:

>210_bases
ATGTCAGATCGTCAGAACGGTGTCGTGAAGTGGTTCAATGATGCCAAGGGCTTCGGCTTCATCACCCCGGAAAGCGGCCC
GGACCTGTTCGTGCATTTCCGTGCCATCCAGGGCACCGGCTTCAAGTCGTTGCAGGAAGGCCAGAAGGTCTCCTTCGTCG
CCGTGCAGGGCCAGAAGGGCATGCAGGCTGACCAGGTGCAGGCGGTCTAA

Upstream 100 bases:

>100_bases
CCGCTCCATCGTTCCGCTTTACCAACGCCTGCAACTCAGTCTCAGCGCCGGTTTTTCGGTTGCTGCGATTTATCCATCTA
AAAGTTCAGGAGTTAGTAAA

Downstream 100 bases:

>100_bases
TCCGTCTGCAACCGTAAGGTTGCCAAAAACGCCGGGCGCGCAAGCGTCCGGCGTTTTTTATTGTCTGCGATTTGTCGCGT
TGACCGGCCTGCGCGTCCTG

Product: major cold shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 69; Mature: 68

Protein sequence:

>69_residues
MSDRQNGVVKWFNDAKGFGFITPESGPDLFVHFRAIQGTGFKSLQEGQKVSFVAVQGQKGMQADQVQAV

Sequences:

>Translated_69_residues
MSDRQNGVVKWFNDAKGFGFITPESGPDLFVHFRAIQGTGFKSLQEGQKVSFVAVQGQKGMQADQVQAV
>Mature_68_residues
SDRQNGVVKWFNDAKGFGFITPESGPDLFVHFRAIQGTGFKSLQEGQKVSFVAVQGQKGMQADQVQAV

Specific function: Binds To And Stimulates The Transcription Of The CCAAT- Containing, Cold-Shock-Inducible Promoters Of The H-Ns And Gyra Proteins. Binds Also To The Inverted Repeat 5'-ATTGG-3'. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Escherichia coli, GI1789979, Length=70, Percent_Identity=58.5714285714286, Blast_Score=81, Evalue=1e-17,
Organism=Escherichia coli, GI1786841, Length=64, Percent_Identity=60.9375, Blast_Score=77, Evalue=3e-16,
Organism=Escherichia coli, GI2367114, Length=67, Percent_Identity=56.7164179104478, Blast_Score=76, Evalue=3e-16,
Organism=Escherichia coli, GI1788126, Length=64, Percent_Identity=62.5, Blast_Score=76, Evalue=4e-16,
Organism=Escherichia coli, GI1787834, Length=70, Percent_Identity=54.2857142857143, Blast_Score=73, Evalue=3e-15,
Organism=Escherichia coli, GI1787839, Length=67, Percent_Identity=53.7313432835821, Blast_Score=71, Evalue=1e-14,
Organism=Escherichia coli, GI1787107, Length=66, Percent_Identity=50, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7547; Mature: 7415

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRQNGVVKWFNDAKGFGFITPESGPDLFVHFRAIQGTGFKSLQEGQKVSFVAVQGQKG
CCCCCCCEEEEECCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEEECCCC
MQADQVQAV
CCCCCEECC
>Mature Secondary Structure 
SDRQNGVVKWFNDAKGFGFITPESGPDLFVHFRAIQGTGFKSLQEGQKVSFVAVQGQKG
CCCCCCEEEEECCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEEECCCC
MQADQVQAV
CCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]