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The map label for this gene is corC [H]

Identifier: 66768104

GI number: 66768104

Start: 2169449

End: 2170327

Strand: Reverse

Name: corC [H]

Synonym: XC_1783

Alternate gene names: 66768104

Gene position: 2170327-2169449 (Counterclockwise)

Preceding gene: 66768105

Following gene: 66768103

Centisome position: 42.15

GC content: 63.48

Gene sequence:

>879_bases
ATGTCCGAAGACGACAGTAGCCAAACCTCAGAATCCCCGGAAAAACGCCGTAGCTGGCTCGAGCGCTTGAGCGCGGCCTT
CTCTGGCGAACCGCATACCCGCGACGAACTGGTCGCCCTGCTGCGCACCGCCGAACAAGACGGTCTCATCGCCGCAGACA
CCTTGCGCATGATGGAAGGCGCGATCTCCGTGTCCGAGCTCACCGTGGGCGACGTGATGATCTCGCGCTCGCAAATGGTG
TCGTTGCCGGTGGAAGCACGCTTCCTCGACCTGATGAAGCAGGTGGTCGAATCCGGCCACTCGCGCTTCCCGGTACACGG
CGAAAACAAGGACGAAGTGCTTGGCATCCTGCTGGCCAAGGACTTGTTGCGCGGCGTGGTGGCCGACAATGGCCCGGGCA
ACGTGCGCGAACTGCTGCGCCCGGCCGTGCTGATCCCCGAGTCGAAGAAGCTCAACGTCCTGCTCAAGGAATTTCGCCTC
TCGCGCAACCATATGGCGATCGTGGTGGACGAGTACGGCGGCGTGGCCGGGCTGGTCACCATCGAAGACGTGCTGGAGCA
GATCGTCGGCGAGATCGACGACGAGCACGACGATGCCGAAGAAGAGAATTCGTTGATCGCCATCCAGGCCGACGGCCGCT
ATGTGGTGGATGCGCTGACGCCGATCGAGGATTTCAACGAGCGCTTCGGCGCCGATTTCCCCGATGACGAATACGACACC
GTGGGCGGACTGGTCACCGATGCAATCGGGCATCTGCCGGAAACCGGCGAGGAGCTGACCCTGGGCCGGTTTGCGTTCCG
CGTGGCCAAGGCAGACGCGCGTCGCGTGCACGCCTTCCACGTCACCATTCTGCCGCCCGACCCGCAGGACGACGCTTGA

Upstream 100 bases:

>100_bases
GCGCGCCAGGTCAGCCACAGCCCCCAGCCACAGACCACTCACGGCTTCCTGCTAGACTTGGCACTATCGCCTGGTTCGCC
GGGTGCCGTTCCCCGTCAAG

Downstream 100 bases:

>100_bases
ACCTGCGCCAGCGCAGCACCGCCGTGCGCGGGCCGGCACGCCACGCCGCCGCATGGTGGGCAGGCTGCAGTGCACTCCTG
CTGCTCGCCCTGCTGAGCCT

Product: polar amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSEDDSSQTSESPEKRRSWLERLSAAFSGEPHTRDELVALLRTAEQDGLIAADTLRMMEGAISVSELTVGDVMISRSQMV
SLPVEARFLDLMKQVVESGHSRFPVHGENKDEVLGILLAKDLLRGVVADNGPGNVRELLRPAVLIPESKKLNVLLKEFRL
SRNHMAIVVDEYGGVAGLVTIEDVLEQIVGEIDDEHDDAEEENSLIAIQADGRYVVDALTPIEDFNERFGADFPDDEYDT
VGGLVTDAIGHLPETGEELTLGRFAFRVAKADARRVHAFHVTILPPDPQDDA

Sequences:

>Translated_292_residues
MSEDDSSQTSESPEKRRSWLERLSAAFSGEPHTRDELVALLRTAEQDGLIAADTLRMMEGAISVSELTVGDVMISRSQMV
SLPVEARFLDLMKQVVESGHSRFPVHGENKDEVLGILLAKDLLRGVVADNGPGNVRELLRPAVLIPESKKLNVLLKEFRL
SRNHMAIVVDEYGGVAGLVTIEDVLEQIVGEIDDEHDDAEEENSLIAIQADGRYVVDALTPIEDFNERFGADFPDDEYDT
VGGLVTDAIGHLPETGEELTLGRFAFRVAKADARRVHAFHVTILPPDPQDDA
>Mature_291_residues
SEDDSSQTSESPEKRRSWLERLSAAFSGEPHTRDELVALLRTAEQDGLIAADTLRMMEGAISVSELTVGDVMISRSQMVS
LPVEARFLDLMKQVVESGHSRFPVHGENKDEVLGILLAKDLLRGVVADNGPGNVRELLRPAVLIPESKKLNVLLKEFRLS
RNHMAIVVDEYGGVAGLVTIEDVLEQIVGEIDDEHDDAEEENSLIAIQADGRYVVDALTPIEDFNERFGADFPDDEYDTV
GGLVTDAIGHLPETGEELTLGRFAFRVAKADARRVHAFHVTILPPDPQDDA

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=208, Percent_Identity=31.25, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI94681046, Length=178, Percent_Identity=30.3370786516854, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI40068055, Length=181, Percent_Identity=29.2817679558011, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40068053, Length=181, Percent_Identity=29.2817679558011, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786879, Length=287, Percent_Identity=46.6898954703833, Blast_Score=237, Evalue=8e-64,
Organism=Escherichia coli, GI87082033, Length=236, Percent_Identity=29.6610169491525, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI145693175, Length=211, Percent_Identity=25.5924170616114, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1790664, Length=257, Percent_Identity=24.9027237354086, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788119, Length=233, Percent_Identity=30.0429184549356, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32121; Mature: 31990

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDDSSQTSESPEKRRSWLERLSAAFSGEPHTRDELVALLRTAEQDGLIAADTLRMMEG
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHH
AISVSELTVGDVMISRSQMVSLPVEARFLDLMKQVVESGHSRFPVHGENKDEVLGILLAK
HCCHHHEEHHHHHHCCHHHEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
DLLRGVVADNGPGNVRELLRPAVLIPESKKLNVLLKEFRLSRNHMAIVVDEYGGVAGLVT
HHHHHHHCCCCCCHHHHHHCCCEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEHH
IEDVLEQIVGEIDDEHDDAEEENSLIAIQADGRYVVDALTPIEDFNERFGADFPDDEYDT
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEHHCCHHHHHHHHCCCCCCCCHHH
VGGLVTDAIGHLPETGEELTLGRFAFRVAKADARRVHAFHVTILPPDPQDDA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
SEDDSSQTSESPEKRRSWLERLSAAFSGEPHTRDELVALLRTAEQDGLIAADTLRMMEG
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHH
AISVSELTVGDVMISRSQMVSLPVEARFLDLMKQVVESGHSRFPVHGENKDEVLGILLAK
HCCHHHEEHHHHHHCCHHHEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
DLLRGVVADNGPGNVRELLRPAVLIPESKKLNVLLKEFRLSRNHMAIVVDEYGGVAGLVT
HHHHHHHCCCCCCHHHHHHCCCEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEHH
IEDVLEQIVGEIDDEHDDAEEENSLIAIQADGRYVVDALTPIEDFNERFGADFPDDEYDT
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEHHCCHHHHHHHHCCCCCCCCHHH
VGGLVTDAIGHLPETGEELTLGRFAFRVAKADARRVHAFHVTILPPDPQDDA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]