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The map label for this gene is ygjG [C]

Identifier: 66768080

GI number: 66768080

Start: 2137217

End: 2138569

Strand: Reverse

Name: ygjG [C]

Synonym: XC_1759

Alternate gene names: 66768080

Gene position: 2138569-2137217 (Counterclockwise)

Preceding gene: 66768086

Following gene: 66768079

Centisome position: 41.54

GC content: 68.37

Gene sequence:

>1353_bases
ATGCACGACCACCCTTCGAGCGATGCCGCCCACGCGATGCAGACACCGGCGGCGATGGAGGCGTTCTGGATGCCGTTCAC
GGCCAACCGGCAGTTCAAGGCGCGCCCGCGCCTGCTGGCCTCGGCTGCAGGCATGTATTACCGCGATGTCGAGGGCCGGC
AGATCCTGGATGGCACCGCGGGGCTGTGGTGCTGCAACGCCGGCCATGCGCGCGAGCGCATCGTCGCGGCGATCCGCGCG
CAGGCCGGCACGCTGGATTTCGCGCCCACCTTCCAGATGGGCTCACCGCTGCCGTTCGCCCTGGCCGAACGGCTGGCCGC
GTTGGCGCCGCCAGGCCTGGGCCATGTGTTCTTCACCAACTCCGGCTCGGAAGCCGTGGATAGCGCGATGAAGATCGTGC
TGGCCTATCACCGCTTGCGCGGCGAGGGCCAGCGCACCCGTTTCATCGGCCGCGAGAAGGCCTACCACGGGGTGGGCTTC
GGCGGGATGTCGATCGGCGGGCTGCCCAATAACCGTAAATGGTTCGGCCCGCTGCTGGCCGGCACCGATCATCTACGGCA
CACGCTGGATCTGCAGCGCAATGCGTATTCGCGGGGACTGCCCGCCTTCGGTGTGGAGCTAGCCGACGACCTGGAACGGC
TGATCACCCTGCACGACGCCTCCACCATCGCCGCAGTGTTCGTCGAACCGGTGTCCGGCTCGGCCGGGGTGATCCTGCCG
CCGGAGGGCTATCTGCAGCGCCTGCGCGCCATCTGCGACCGCCACGGCATCGTGCTGGTGTTCGACGAGGTGATCACCGG
CTTCGGGCGCGTGGGCGAGGCGTTCGCCGCGCAGCGCTTCGGGGTGACCCCGGACCTGATCACCGCCGCCAAGGGCCTGA
CCAGCGGCACGGTGCCGATGGGCGCGGTGCTGGTGGCCGATGCGATCCACGATGCCTTCATGCATGGGCCGCAGGCGGCG
ATCGAGCTGTTCCATGGCTACACCTATTCCGGACATCCGCTGGCCTGCGCCGCAGCCCTGGCCACGCTGGACACCTACGC
CGAAGAACAGCTGTTCACGCGGGCAATTACGCTGGGGCCGCAGTGGGAGGAGGCGTTGCACAGCCTGCGCGGACTGCCGC
ACGTCATCGACATCCGCAACATCGGCTTGATCGGTGCGATCGAACTGGCGCCGCGCGAGGGTGCCCCGGGGGCGCGCGGT
TACGAGGTGTTCGAACGCTGCTTCCACGAGGGCGGCCTGCTGGTGCGTGTCACCGGCGATGTCATTGCGTTGTCGCCGCC
GTTGATCGTCACCCCCGACCAGATCGGACAAATGGTGGAGACGCTGGCCGCGATCCTGCGCAAGGTGGACTAA

Upstream 100 bases:

>100_bases
GGCCGCCACGCGGCCCGGGTGCGCCAGGTGCGCGCCGCTGCGGTTCCAGATGACGCAGCTGCTGCCGTAGAGTCGGCCCA
TCCCCGCCCCGGAGTCTGCG

Downstream 100 bases:

>100_bases
AGGCCTTGCAGTGCGAGCGGCCGCTCGCATTGGCGTGCCGACGCGCTGGCTGGCCAGTGTGTCACCGGGCCGCGCCATGG
CCGGCTGCCCTGCCCGCCAC

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MHDHPSSDAAHAMQTPAAMEAFWMPFTANRQFKARPRLLASAAGMYYRDVEGRQILDGTAGLWCCNAGHARERIVAAIRA
QAGTLDFAPTFQMGSPLPFALAERLAALAPPGLGHVFFTNSGSEAVDSAMKIVLAYHRLRGEGQRTRFIGREKAYHGVGF
GGMSIGGLPNNRKWFGPLLAGTDHLRHTLDLQRNAYSRGLPAFGVELADDLERLITLHDASTIAAVFVEPVSGSAGVILP
PEGYLQRLRAICDRHGIVLVFDEVITGFGRVGEAFAAQRFGVTPDLITAAKGLTSGTVPMGAVLVADAIHDAFMHGPQAA
IELFHGYTYSGHPLACAAALATLDTYAEEQLFTRAITLGPQWEEALHSLRGLPHVIDIRNIGLIGAIELAPREGAPGARG
YEVFERCFHEGGLLVRVTGDVIALSPPLIVTPDQIGQMVETLAAILRKVD

Sequences:

>Translated_450_residues
MHDHPSSDAAHAMQTPAAMEAFWMPFTANRQFKARPRLLASAAGMYYRDVEGRQILDGTAGLWCCNAGHARERIVAAIRA
QAGTLDFAPTFQMGSPLPFALAERLAALAPPGLGHVFFTNSGSEAVDSAMKIVLAYHRLRGEGQRTRFIGREKAYHGVGF
GGMSIGGLPNNRKWFGPLLAGTDHLRHTLDLQRNAYSRGLPAFGVELADDLERLITLHDASTIAAVFVEPVSGSAGVILP
PEGYLQRLRAICDRHGIVLVFDEVITGFGRVGEAFAAQRFGVTPDLITAAKGLTSGTVPMGAVLVADAIHDAFMHGPQAA
IELFHGYTYSGHPLACAAALATLDTYAEEQLFTRAITLGPQWEEALHSLRGLPHVIDIRNIGLIGAIELAPREGAPGARG
YEVFERCFHEGGLLVRVTGDVIALSPPLIVTPDQIGQMVETLAAILRKVD
>Mature_450_residues
MHDHPSSDAAHAMQTPAAMEAFWMPFTANRQFKARPRLLASAAGMYYRDVEGRQILDGTAGLWCCNAGHARERIVAAIRA
QAGTLDFAPTFQMGSPLPFALAERLAALAPPGLGHVFFTNSGSEAVDSAMKIVLAYHRLRGEGQRTRFIGREKAYHGVGF
GGMSIGGLPNNRKWFGPLLAGTDHLRHTLDLQRNAYSRGLPAFGVELADDLERLITLHDASTIAAVFVEPVSGSAGVILP
PEGYLQRLRAICDRHGIVLVFDEVITGFGRVGEAFAAQRFGVTPDLITAAKGLTSGTVPMGAVLVADAIHDAFMHGPQAA
IELFHGYTYSGHPLACAAALATLDTYAEEQLFTRAITLGPQWEEALHSLRGLPHVIDIRNIGLIGAIELAPREGAPGARG
YEVFERCFHEGGLLVRVTGDVIALSPPLIVTPDQIGQMVETLAAILRKVD

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=412, Percent_Identity=29.126213592233, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI284507298, Length=328, Percent_Identity=29.8780487804878, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI37574042, Length=428, Percent_Identity=29.4392523364486, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI13994255, Length=438, Percent_Identity=27.6255707762557, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI226442705, Length=428, Percent_Identity=29.4392523364486, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24119277, Length=435, Percent_Identity=26.2068965517241, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=29.8469387755102, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=32.7365728900256, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1786991, Length=434, Percent_Identity=31.1059907834101, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1789759, Length=449, Percent_Identity=30.2895322939866, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789016, Length=408, Percent_Identity=32.1078431372549, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1788044, Length=439, Percent_Identity=28.7015945330296, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1787560, Length=424, Percent_Identity=31.3679245283019, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786349, Length=361, Percent_Identity=30.4709141274238, Blast_Score=95, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=419, Percent_Identity=27.4463007159904, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=27.5626423690205, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71992977, Length=438, Percent_Identity=26.9406392694064, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=248, Percent_Identity=31.4516129032258, Blast_Score=128, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6323470, Length=437, Percent_Identity=27.4599542334096, Blast_Score=165, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6324386, Length=450, Percent_Identity=26.2222222222222, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324432, Length=416, Percent_Identity=26.4423076923077, Blast_Score=116, Evalue=9e-27,
Organism=Drosophila melanogaster, GI21357415, Length=420, Percent_Identity=27.6190476190476, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=29.4784580498866, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI28574759, Length=437, Percent_Identity=29.7482837528604, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI21356575, Length=434, Percent_Identity=27.8801843317972, Blast_Score=115, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48321; Mature: 48321

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDHPSSDAAHAMQTPAAMEAFWMPFTANRQFKARPRLLASAAGMYYRDVEGRQILDGTA
CCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEECCCCCEEECCCC
GLWCCNAGHARERIVAAIRAQAGTLDFAPTFQMGSPLPFALAERLAALAPPGLGHVFFTN
CEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEC
SGSEAVDSAMKIVLAYHRLRGEGQRTRFIGREKAYHGVGFGGMSIGGLPNNRKWFGPLLA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCCCCCEECCCCCCCCCCCHHHH
GTDHLRHTLDLQRNAYSRGLPAFGVELADDLERLITLHDASTIAAVFVEPVSGSAGVILP
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEC
PEGYLQRLRAICDRHGIVLVFDEVITGFGRVGEAFAAQRFGVTPDLITAAKGLTSGTVPM
CHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCH
GAVLVADAIHDAFMHGPQAAIELFHGYTYSGHPLACAAALATLDTYAEEQLFTRAITLGP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QWEEALHSLRGLPHVIDIRNIGLIGAIELAPREGAPGARGYEVFERCFHEGGLLVRVTGD
CHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEECC
VIALSPPLIVTPDQIGQMVETLAAILRKVD
EEEECCCEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHDHPSSDAAHAMQTPAAMEAFWMPFTANRQFKARPRLLASAAGMYYRDVEGRQILDGTA
CCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEECCCCCEEECCCC
GLWCCNAGHARERIVAAIRAQAGTLDFAPTFQMGSPLPFALAERLAALAPPGLGHVFFTN
CEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEC
SGSEAVDSAMKIVLAYHRLRGEGQRTRFIGREKAYHGVGFGGMSIGGLPNNRKWFGPLLA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCCCCCEECCCCCCCCCCCHHHH
GTDHLRHTLDLQRNAYSRGLPAFGVELADDLERLITLHDASTIAAVFVEPVSGSAGVILP
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEC
PEGYLQRLRAICDRHGIVLVFDEVITGFGRVGEAFAAQRFGVTPDLITAAKGLTSGTVPM
CHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCH
GAVLVADAIHDAFMHGPQAAIELFHGYTYSGHPLACAAALATLDTYAEEQLFTRAITLGP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QWEEALHSLRGLPHVIDIRNIGLIGAIELAPREGAPGARGYEVFERCFHEGGLLVRVTGD
CHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEECC
VIALSPPLIVTPDQIGQMVETLAAILRKVD
EEEECCCEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]