Click here to switch to the map view.

The map label for this gene is rpfG [H]

Identifier: 66768076

GI number: 66768076

Start: 2128943

End: 2129926

Strand: Reverse

Name: rpfG [H]

Synonym: XC_1755

Alternate gene names: 66768076

Gene position: 2129926-2128943 (Counterclockwise)

Preceding gene: 66768077

Following gene: 66768075

Centisome position: 41.37

GC content: 68.29

Gene sequence:

>984_bases
ATGCCAGCCCGTCCCCTGCTCTGCGTTGACGATGAATCCAGCAATCTGGCCACCCTGCGCCAGTTGCTGCGCGACGACTA
TCCACTGGTATTCGCCAAATCCGGCGGTGAAGCCCTGGATGCGGTGGCGCGGCATGCGCCGGCGCTGATCCTGCTGGACG
TGGAACTGCCGGACATGGATGGCTACGCAGTGGCGCGCACACTCAAGCAGGACCCGGACAGCACCGCCATCCCGATCCTG
TTCGTGACCTCGCGCAGTACCGAGCACGACGAGCGCACCGGCCTGGAGGCAGGCGCCGCCGATTACGTGAGCCGGCCCTA
CTCCGCCGCCTTGCTCAAGGCGCGCATCGCCACGCATCTGACCCTGGCCGAAAATGCGCGCCTGGCGCAGCAATACCGCG
ACGCCATCCATCTGCTGGGCACCGCCGGCCAGGGCCAGGACGCGGACACCGGCGCGCATATCTGGCGCATGGCTGCCTAT
GCGCGCCTGCTAGCGGAGAAAGTCGGCTGGCCACCCGCGCAGGCACAGCTGCTGGAAGATGCCGCGCCGCTGCATGACGC
CGGCAAGATCGTCGTGCCCGGCAGCATCCTGCACAAGCCCGATACCCTGGACGAGCACGAGCGCGAGGTGGTGCGCCAGC
ATCCCCAGGTGGGCCACGACCTGCTGCGGCACGGCCGCGGGCCGCTGTTCCAGCTGGCTGCCGATATCGCCCTGCACCAC
CACGAATGCTGGGACGGCAGCGGTTATCCGCAGGGCGTGGCGGGCGATGCCATCCCCGAAGCCGCCCGCATCGTGGCGGT
GGCCGATGTGTTCGATGCACTGTGCGGGCGCCGCGCCTACAAAGCGCCGTGGGCGGTGGAAGATGCCATGCGCAAGCTCG
ACAGCATGGCCGGGAAGCAACTGGAGCCGCGCCTGGTGCACGCGTTTCGCGATGCCCTGCCGCAGATGCTGCAGATCAAG
GACGCCTGGGATCGGGAGCGTTGA

Upstream 100 bases:

>100_bases
GGACGACTTCGATTTCCGCCGCGCCGAAGCCACCCTGCGCGATTGGCAAGCCAACCACCCACGCTGACCGTGTCCCCGTA
CCGGTTCGCAAGGATTCCGC

Downstream 100 bases:

>100_bases
GAGATGGGAATCGGGAGTTGGGAATCGGGAATGGGGGGTCCATCAGGGCGTTGTTGATTTTGGTGCTGTAGCGCGCACTC
GGATTCGCCAGGCGGTGCGT

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPARPLLCVDDESSNLATLRQLLRDDYPLVFAKSGGEALDAVARHAPALILLDVELPDMDGYAVARTLKQDPDSTAIPIL
FVTSRSTEHDERTGLEAGAADYVSRPYSAALLKARIATHLTLAENARLAQQYRDAIHLLGTAGQGQDADTGAHIWRMAAY
ARLLAEKVGWPPAQAQLLEDAAPLHDAGKIVVPGSILHKPDTLDEHEREVVRQHPQVGHDLLRHGRGPLFQLAADIALHH
HECWDGSGYPQGVAGDAIPEAARIVAVADVFDALCGRRAYKAPWAVEDAMRKLDSMAGKQLEPRLVHAFRDALPQMLQIK
DAWDRER

Sequences:

>Translated_327_residues
MPARPLLCVDDESSNLATLRQLLRDDYPLVFAKSGGEALDAVARHAPALILLDVELPDMDGYAVARTLKQDPDSTAIPIL
FVTSRSTEHDERTGLEAGAADYVSRPYSAALLKARIATHLTLAENARLAQQYRDAIHLLGTAGQGQDADTGAHIWRMAAY
ARLLAEKVGWPPAQAQLLEDAAPLHDAGKIVVPGSILHKPDTLDEHEREVVRQHPQVGHDLLRHGRGPLFQLAADIALHH
HECWDGSGYPQGVAGDAIPEAARIVAVADVFDALCGRRAYKAPWAVEDAMRKLDSMAGKQLEPRLVHAFRDALPQMLQIK
DAWDRER
>Mature_326_residues
PARPLLCVDDESSNLATLRQLLRDDYPLVFAKSGGEALDAVARHAPALILLDVELPDMDGYAVARTLKQDPDSTAIPILF
VTSRSTEHDERTGLEAGAADYVSRPYSAALLKARIATHLTLAENARLAQQYRDAIHLLGTAGQGQDADTGAHIWRMAAYA
RLLAEKVGWPPAQAQLLEDAAPLHDAGKIVVPGSILHKPDTLDEHEREVVRQHPQVGHDLLRHGRGPLFQLAADIALHHH
ECWDGSGYPQGVAGDAIPEAARIVAVADVFDALCGRRAYKAPWAVEDAMRKLDSMAGKQLEPRLVHAFRDALPQMLQIKD
AWDRER

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG3437

COG function: function code KT; Response regulator containing a CheY-like receiver domain and an HD-GYP domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=198, Percent_Identity=31.3131313131313, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790860, Length=113, Percent_Identity=37.1681415929204, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786911, Length=116, Percent_Identity=37.9310344827586, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=34.453781512605, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790863, Length=136, Percent_Identity=27.9411764705882, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=33.8842975206612, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1790437, Length=135, Percent_Identity=36.2962962962963, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 35803; Mature: 35672

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARPLLCVDDESSNLATLRQLLRDDYPLVFAKSGGEALDAVARHAPALILLDVELPDMD
CCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCEEEEEEEECCCCC
GYAVARTLKQDPDSTAIPILFVTSRSTEHDERTGLEAGAADYVSRPYSAALLKARIATHL
CHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHH
TLAENARLAQQYRDAIHLLGTAGQGQDADTGAHIWRMAAYARLLAEKVGWPPAQAQLLED
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AAPLHDAGKIVVPGSILHKPDTLDEHEREVVRQHPQVGHDLLRHGRGPLFQLAADIALHH
HCCCCCCCCEEECCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHH
HECWDGSGYPQGVAGDAIPEAARIVAVADVFDALCGRRAYKAPWAVEDAMRKLDSMAGKQ
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCC
LEPRLVHAFRDALPQMLQIKDAWDRER
CCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PARPLLCVDDESSNLATLRQLLRDDYPLVFAKSGGEALDAVARHAPALILLDVELPDMD
CCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCEEEEEEEECCCCC
GYAVARTLKQDPDSTAIPILFVTSRSTEHDERTGLEAGAADYVSRPYSAALLKARIATHL
CHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHH
TLAENARLAQQYRDAIHLLGTAGQGQDADTGAHIWRMAAYARLLAEKVGWPPAQAQLLED
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AAPLHDAGKIVVPGSILHKPDTLDEHEREVVRQHPQVGHDLLRHGRGPLFQLAADIALHH
HCCCCCCCCEEECCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHH
HECWDGSGYPQGVAGDAIPEAARIVAVADVFDALCGRRAYKAPWAVEDAMRKLDSMAGKQ
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCC
LEPRLVHAFRDALPQMLQIKDAWDRER
CCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]