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The map label for this gene is htpG [H]

Identifier: 66768044

GI number: 66768044

Start: 2080162

End: 2082066

Strand: Reverse

Name: htpG [H]

Synonym: XC_1721

Alternate gene names: 66768044

Gene position: 2082066-2080162 (Counterclockwise)

Preceding gene: 66768051

Following gene: 66768043

Centisome position: 40.44

GC content: 62.99

Gene sequence:

>1905_bases
ATGACCGTTGATACCGACAAGCAGACGCTGGGCTTCCAGACCGAGGTCAAGCAGCTGCTGCAGCTGATGATCCACTCGCT
GTATTCCAACAAGGAAATCTTCCTGCGCGAGCTGGTGTCCAATGCCGCCGACGCCGCCGACAAGCTGCGCTTCGAAGCCT
TGGTCAAGCCCGACCTGCTGGAAGGCAGCGGCGAGCTGCGCATCCGCGTCGACTTCGACAAGGACGCGCGCACCGTCACC
ATCGACGACAATGGCATCGGCATGAGCCGCGAGGACGCGGTGTCCCACCTGGGCACCATCGCCAAGTCCGGCACCGCCGA
CTTCCTCAAGCATCTGAGCGGCGACCAGAAAAAGGACGCCAACCTCATTGGCCAGTTCGGCGTAGGCTTCTACAGCGCCT
TCATCGTTGCCGACCAGGTCGACGTGTATTCGCGCCGCGCCGGCCTGCCCGCCAGCGACGGCGTGCATTGGTCCTCGCGC
GGTGAGGGCGAGTTCGAAGTCGCCAGCGTCGACAAGCCCGAGCGCGGCACCCGCATCGTGTTGCAGCTGAAGGAAGGCGA
AGAGTCCTTTGCCGATGGCTGGACCCTGCGCAACATCCTCAAGAAGTATTCCGATCACATCGGCCTGCCGATCGAGATGC
GCAAGGAGCACTACGGCGAAGACGCCGACAAACCCGCCGAACCCGAGTGGGAAGTGGTCAACCGCGCCAGCGCGCTGTGG
ACCCGCCCCAAGTCCGAGATCAAGGACGAGGAGTACCAGGAGTTCTACAAGCACGTTGCGCACGATGCCGGTAATCCGCT
GGCGTGGAGCCATAACAAGGTCGAAGGCAAGCTGGATTACACCTCGCTGCTGTTCGTGCCCGGCCGCGCCCCGTTCGACC
TGTACCACCGCGATTCGGCCAAGGGCCTGAAGCTGTACGTGCAGCGCGTTTTCATCATGGACCAGGCCGAGCAGTTCCTG
CCGCTGTACCTGCGCTTCATCAAGGGCGTGGTGGATTCGGCCGACCTGTCGCTCAATGTCTCGCGCGAGATCCTGCAGTC
CGGCCCGGTGGTGGATTCGATGAAGTCCGCGCTGACCAAGCGTGCGCTGGACATGCTGGAAAAACTGGCCAAGGACAAGC
CGGATGACTACGCCACCTTCTGGCGCAACTTCGGCCAGGCGCTGAAGGAAGGCCCCGCCGAGGACTACGCCAACCGCGAA
AAGGTCGCCGGCCTGCTGCGTTTCTCGTCCACCCACGACACCACCGGCGCGCAAAGCGTGGCGCTGGCCGATTATGTGGG
CCGCATGACCGAAGGTCAGGACAAGCTGTACTACCTCACCGGCGAGAGCTACGCGCAGATCAAGGACAGCCCGCACCTGG
AGGTGTTCCGCAAGAAGGGCATCGAGGTGCTGCTGCTCACCGACCGCATCGACGAATGGCTGATGAGCTACCTCACCGAA
TTCGACAGCAAATCGTTCGTGGACGTGGCCCGCGGCGATCTGGACCTGGGCAAGCTGGATTCGGAAGAGGATAAGAAGGC
GCAGGAAGAAGTCGCCAAGTCCAAGGAAGGCCTGGCCTCGCGCATCAAGGCCGCCCTCGGCGACGACGTGGCCGAAGTGC
GCGTCTCGCACCGCCTGACCGACTCCCCCGCCATCCTGGCCATCGGCCAAGGCGACCTGGGCCTGCAGATGCGTCAGCTG
CTCGAAGCCAGCGGCCAGGCCGTGCCGGAAACCAAGCCGGTGTTCGAATTCAACCCGGCCCACCCGCTGATCGAAAAGCT
GGATGCGGAACAAGATATGGACCGGTTTGGCGATTTGAGCCGGGTGTTGTTCGACCAGGCTGCGCTGGCTGCGGGCGATA
GCCTCAAGGATCCGGCAGGGTATGTGCGGCGGTTGAACAAGTTGTTGTTGGAGTTGTCGGCTTAA

Upstream 100 bases:

>100_bases
GCTGAATCCTGCCATCAGGCCTTGAAAAATTTCGCATGCAGCCTCATCCCCCAGGCCATCGGCCGCACTGCGGCCCAGGC
CACCACGGAGCACGACCACA

Downstream 100 bases:

>100_bases
AGCTTACGACACACTGGTGATACACCAAGACCGGCGCATGCGCCGGTCTTTTTTTATGTCTATCCTGGCTTATGGAAGAC
GCCTCACCTGCGTCGCAGAT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MTVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPDLLEGSGELRIRVDFDKDARTVT
IDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDANLIGQFGVGFYSAFIVADQVDVYSRRAGLPASDGVHWSSR
GEGEFEVASVDKPERGTRIVLQLKEGEESFADGWTLRNILKKYSDHIGLPIEMRKEHYGEDADKPAEPEWEVVNRASALW
TRPKSEIKDEEYQEFYKHVAHDAGNPLAWSHNKVEGKLDYTSLLFVPGRAPFDLYHRDSAKGLKLYVQRVFIMDQAEQFL
PLYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKSALTKRALDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANRE
KVAGLLRFSSTHDTTGAQSVALADYVGRMTEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTE
FDSKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGDDVAEVRVSHRLTDSPAILAIGQGDLGLQMRQL
LEASGQAVPETKPVFEFNPAHPLIEKLDAEQDMDRFGDLSRVLFDQAALAAGDSLKDPAGYVRRLNKLLLELSA

Sequences:

>Translated_634_residues
MTVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPDLLEGSGELRIRVDFDKDARTVT
IDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDANLIGQFGVGFYSAFIVADQVDVYSRRAGLPASDGVHWSSR
GEGEFEVASVDKPERGTRIVLQLKEGEESFADGWTLRNILKKYSDHIGLPIEMRKEHYGEDADKPAEPEWEVVNRASALW
TRPKSEIKDEEYQEFYKHVAHDAGNPLAWSHNKVEGKLDYTSLLFVPGRAPFDLYHRDSAKGLKLYVQRVFIMDQAEQFL
PLYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKSALTKRALDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANRE
KVAGLLRFSSTHDTTGAQSVALADYVGRMTEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTE
FDSKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGDDVAEVRVSHRLTDSPAILAIGQGDLGLQMRQL
LEASGQAVPETKPVFEFNPAHPLIEKLDAEQDMDRFGDLSRVLFDQAALAAGDSLKDPAGYVRRLNKLLLELSA
>Mature_633_residues
TVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPDLLEGSGELRIRVDFDKDARTVTI
DDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDANLIGQFGVGFYSAFIVADQVDVYSRRAGLPASDGVHWSSRG
EGEFEVASVDKPERGTRIVLQLKEGEESFADGWTLRNILKKYSDHIGLPIEMRKEHYGEDADKPAEPEWEVVNRASALWT
RPKSEIKDEEYQEFYKHVAHDAGNPLAWSHNKVEGKLDYTSLLFVPGRAPFDLYHRDSAKGLKLYVQRVFIMDQAEQFLP
LYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKSALTKRALDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANREK
VAGLLRFSSTHDTTGAQSVALADYVGRMTEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTEF
DSKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGDDVAEVRVSHRLTDSPAILAIGQGDLGLQMRQLL
EASGQAVPETKPVFEFNPAHPLIEKLDAEQDMDRFGDLSRVLFDQAALAAGDSLKDPAGYVRRLNKLLLELSA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=680, Percent_Identity=37.9411764705882, Blast_Score=430, Evalue=1e-120,
Organism=Homo sapiens, GI155722983, Length=633, Percent_Identity=34.913112164297, Blast_Score=359, Evalue=3e-99,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=38.2926829268293, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=38.2926829268293, Blast_Score=265, Evalue=1e-70,
Organism=Homo sapiens, GI20149594, Length=410, Percent_Identity=37.8048780487805, Blast_Score=265, Evalue=1e-70,
Organism=Escherichia coli, GI1786679, Length=624, Percent_Identity=59.4551282051282, Blast_Score=774, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=668, Percent_Identity=38.622754491018, Blast_Score=442, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17542208, Length=668, Percent_Identity=36.377245508982, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI115535205, Length=644, Percent_Identity=34.3167701863354, Blast_Score=338, Evalue=5e-93,
Organism=Caenorhabditis elegans, GI115535167, Length=440, Percent_Identity=36.5909090909091, Blast_Score=273, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6323840, Length=676, Percent_Identity=36.8343195266272, Blast_Score=422, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6325016, Length=209, Percent_Identity=41.1483253588517, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=38.5401459854015, Blast_Score=440, Evalue=1e-123,
Organism=Drosophila melanogaster, GI21357739, Length=683, Percent_Identity=36.3103953147877, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24586016, Length=638, Percent_Identity=33.6990595611285, Blast_Score=357, Evalue=9e-99,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70833; Mature: 70701

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPDLL
CCCCCCCHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
EGSGELRIRVDFDKDARTVTIDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDA
CCCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCH
NLIGQFGVGFYSAFIVADQVDVYSRRAGLPASDGVHWSSRGEGEFEVASVDKPERGTRIV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEE
LQLKEGEESFADGWTLRNILKKYSDHIGLPIEMRKEHYGEDADKPAEPEWEVVNRASALW
EEEECCCHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
TRPKSEIKDEEYQEFYKHVAHDAGNPLAWSHNKVEGKLDYTSLLFVPGRAPFDLYHRDSA
CCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECEEEEEEECCCCCCCHHCCCCC
KGLKLYVQRVFIMDQAEQFLPLYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKSALTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHCCCCHHHHHHHHHH
RALDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANREKVAGLLRFSSTHDTTGAQSV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCCCCCCCHHH
ALADYVGRMTEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTE
HHHHHHHHHCCCCCCEEEEECCCHHHCCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHH
FDSKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGDDVAEVRVSHRLT
HCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DSPAILAIGQGDLGLQMRQLLEASGQAVPETKPVFEFNPAHPLIEKLDAEQDMDRFGDLS
CCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHCCHHHHHHHHHHH
RVLFDQAALAAGDSLKDPAGYVRRLNKLLLELSA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPDLL
CCCCCCHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
EGSGELRIRVDFDKDARTVTIDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDA
CCCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCH
NLIGQFGVGFYSAFIVADQVDVYSRRAGLPASDGVHWSSRGEGEFEVASVDKPERGTRIV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEE
LQLKEGEESFADGWTLRNILKKYSDHIGLPIEMRKEHYGEDADKPAEPEWEVVNRASALW
EEEECCCHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
TRPKSEIKDEEYQEFYKHVAHDAGNPLAWSHNKVEGKLDYTSLLFVPGRAPFDLYHRDSA
CCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECEEEEEEECCCCCCCHHCCCCC
KGLKLYVQRVFIMDQAEQFLPLYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKSALTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHCCCCHHHHHHHHHH
RALDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANREKVAGLLRFSSTHDTTGAQSV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCCCCCCCHHH
ALADYVGRMTEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTE
HHHHHHHHHCCCCCCEEEEECCCHHHCCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHH
FDSKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGDDVAEVRVSHRLT
HCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DSPAILAIGQGDLGLQMRQLLEASGQAVPETKPVFEFNPAHPLIEKLDAEQDMDRFGDLS
CCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHCCHHHHHHHHHHH
RVLFDQAALAAGDSLKDPAGYVRRLNKLLLELSA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]