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The map label for this gene is zraS [C]

Identifier: 66768015

GI number: 66768015

Start: 2030298

End: 2031920

Strand: Direct

Name: zraS [C]

Synonym: XC_1691

Alternate gene names: 66768015

Gene position: 2030298-2031920 (Clockwise)

Preceding gene: 66768014

Following gene: 66768016

Centisome position: 39.43

GC content: 62.17

Gene sequence:

>1623_bases
TTGAACGATTCCGGTTACGGAGAGCCACGGGCGCCATTGATTGGCGAATCGCAGACGCTTCCGGTCAGCAAGCATCGCTC
GGACATCTTCTTTGCTGCGGTGGAAACCACCCGCATGCCGATGACGGTGACCGACCCATACCTGCCGGATAACCCGATCG
TGTTCGCCAACCGGGCCTTCCTGGAAATGACCGGGTACGCTGCCGACGAAATCATCGGCAACAACTGCCGCTTCCTGCAG
GGCCCGGAGACCGACCGCCAGGCGGTGGCCGATGTGCGTGAGGCCATCGACAACCGCCGCGAATTCGCCACTGAAGTGCT
GAATTATCGCAAGGACGGCTCAACATTCTGGAATGCGCTGTTCGTTTCTCCGGTCTTCGATGACACCGGCAAGCTGGTGT
ATTTCTTTGGCTCGCAGCTGGACGTCAGCCGCCGCCGTGATGCCGAAGATGCCCTGCGCCAGGCGCAGAAGATGGAAGCG
CTGGGCCAGCTCACCGGCGGCATTGCACACGACTTCAACAATCTGCTGCAGGTGATGTCCGGGCATCTGGAATTCATCCA
GATGATGGTCAGCAACGGCAACGGCAGCCCCGATCGCATCGCGGTCAGCGCGGAGCACGCCGCCGCGGCGGCGGCCAAGG
CCGCGACCTTGACCCAGCAGTTGCTGGCGTTTTCGCGTAAACAGAAATTGCGTGGCCGGGTGGTGAATCTCAACGGCCTG
GTGTCGGGCATGAACAATATGGCCGAGCGCGCGCTGGGGGGCGGCATCACATTGCGTCAGGCGCTGGAAGAACGGCTGTG
GAATTGCCAGATCGACACGACGCAGGCGGAAGTGGCGCTGTTGAATGTGCTGATCAATGCGCGTGACGCCATGGCCAATG
CCGAGCGCAAGGAAGTGATGGTGCAGACGCAGAATGTGGAGATCACCAGCCACGACCTGTCGATGTATCACCAGCTCGCG
CCGGGCCGCTACGTGAGTATTGCCGTGACCGACAGCGGCTCGGGCATGCCGCCGGAAGTGGTGAGCCGGGTCATGGAGCC
GTTCTTCACCACCAAGGAAGAGGGGCAGGGCACGGGCCTGGGCTTGTCGATGGTGTATGGCTTCGTCAAGCAATCCGGTG
GCACCGTGCGCATCTACAGCGAAGTGGGCGAAGGCACCACGGTGCGGCTGTATTTCCCCGCCTCCAGCGATTACGAAAAC
GCGCTGCCGTCCACCAAGAACCGCGCCTTGGACAAGGGCGGCAACGAAACCATCCTGATCGTGGAAGACAAGGAGGACGT
GGCGGTGGTGGCCAAGATGTTCCTGGAAGGTGCCGGTTATCGCGCGCTGTCCGCGTCGAGCGGGCGCGAAGCGATCGAGG
TGCTGGAGCAGCATCCGGAAGTGGACGCCTTGTTCACCGACCTGATCATGCCAGGCGGCATGAACGGCGTGGTGCTGGCG
CGCGAAGCACGGCGGATGCTGCCCAAGATCAAGGTGCTGCTGACCACCGGCTATGCCGATGCCAGCATCCAGCGCACCGA
TGTGGGCGGCGCGGAGTTCGACGTGGTCAACAAGCCGTACACGCAGAAGGAATTGCTCAAGCGCATTCGCATGTTGCTGG
ATGGTCCCACCGGCGTTGGTTGA

Upstream 100 bases:

>100_bases
CGGTCATTTGCCGGTCTGGAAAGGCTCACGGATGTGATGGGGGCCTCACCGGGCTCGTCTAAACTAGCGCCACGGGAATG
GCCCCGCGGAGAGCACGCAC

Downstream 100 bases:

>100_bases
ATACGTGCAGGTGCCGGCGCGGCCTGGAGTGCCCGGCAGTGGCCCATCCGTGAACGCGTGGCCAGGCACGCGCGCACTTT
CAGCCAGGCATGACATCCGG

Product: histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MNDSGYGEPRAPLIGESQTLPVSKHRSDIFFAAVETTRMPMTVTDPYLPDNPIVFANRAFLEMTGYAADEIIGNNCRFLQ
GPETDRQAVADVREAIDNRREFATEVLNYRKDGSTFWNALFVSPVFDDTGKLVYFFGSQLDVSRRRDAEDALRQAQKMEA
LGQLTGGIAHDFNNLLQVMSGHLEFIQMMVSNGNGSPDRIAVSAEHAAAAAAKAATLTQQLLAFSRKQKLRGRVVNLNGL
VSGMNNMAERALGGGITLRQALEERLWNCQIDTTQAEVALLNVLINARDAMANAERKEVMVQTQNVEITSHDLSMYHQLA
PGRYVSIAVTDSGSGMPPEVVSRVMEPFFTTKEEGQGTGLGLSMVYGFVKQSGGTVRIYSEVGEGTTVRLYFPASSDYEN
ALPSTKNRALDKGGNETILIVEDKEDVAVVAKMFLEGAGYRALSASSGREAIEVLEQHPEVDALFTDLIMPGGMNGVVLA
REARRMLPKIKVLLTTGYADASIQRTDVGGAEFDVVNKPYTQKELLKRIRMLLDGPTGVG

Sequences:

>Translated_540_residues
MNDSGYGEPRAPLIGESQTLPVSKHRSDIFFAAVETTRMPMTVTDPYLPDNPIVFANRAFLEMTGYAADEIIGNNCRFLQ
GPETDRQAVADVREAIDNRREFATEVLNYRKDGSTFWNALFVSPVFDDTGKLVYFFGSQLDVSRRRDAEDALRQAQKMEA
LGQLTGGIAHDFNNLLQVMSGHLEFIQMMVSNGNGSPDRIAVSAEHAAAAAAKAATLTQQLLAFSRKQKLRGRVVNLNGL
VSGMNNMAERALGGGITLRQALEERLWNCQIDTTQAEVALLNVLINARDAMANAERKEVMVQTQNVEITSHDLSMYHQLA
PGRYVSIAVTDSGSGMPPEVVSRVMEPFFTTKEEGQGTGLGLSMVYGFVKQSGGTVRIYSEVGEGTTVRLYFPASSDYEN
ALPSTKNRALDKGGNETILIVEDKEDVAVVAKMFLEGAGYRALSASSGREAIEVLEQHPEVDALFTDLIMPGGMNGVVLA
REARRMLPKIKVLLTTGYADASIQRTDVGGAEFDVVNKPYTQKELLKRIRMLLDGPTGVG
>Mature_540_residues
MNDSGYGEPRAPLIGESQTLPVSKHRSDIFFAAVETTRMPMTVTDPYLPDNPIVFANRAFLEMTGYAADEIIGNNCRFLQ
GPETDRQAVADVREAIDNRREFATEVLNYRKDGSTFWNALFVSPVFDDTGKLVYFFGSQLDVSRRRDAEDALRQAQKMEA
LGQLTGGIAHDFNNLLQVMSGHLEFIQMMVSNGNGSPDRIAVSAEHAAAAAAKAATLTQQLLAFSRKQKLRGRVVNLNGL
VSGMNNMAERALGGGITLRQALEERLWNCQIDTTQAEVALLNVLINARDAMANAERKEVMVQTQNVEITSHDLSMYHQLA
PGRYVSIAVTDSGSGMPPEVVSRVMEPFFTTKEEGQGTGLGLSMVYGFVKQSGGTVRIYSEVGEGTTVRLYFPASSDYEN
ALPSTKNRALDKGGNETILIVEDKEDVAVVAKMFLEGAGYRALSASSGREAIEVLEQHPEVDALFTDLIMPGGMNGVVLA
REARRMLPKIKVLLTTGYADASIQRTDVGGAEFDVVNKPYTQKELLKRIRMLLDGPTGVG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI6912446, Length=95, Percent_Identity=37.8947368421053, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI38569493, Length=142, Percent_Identity=28.8732394366197, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI27886667, Length=94, Percent_Identity=32.9787234042553, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=265, Percent_Identity=28.3018867924528, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788549, Length=335, Percent_Identity=23.2835820895522, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI48994928, Length=510, Percent_Identity=22.3529411764706, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17136946, Length=101, Percent_Identity=30.6930693069307, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59022; Mature: 59022

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSGYGEPRAPLIGESQTLPVSKHRSDIFFAAVETTRMPMTVTDPYLPDNPIVFANRAF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEECCEE
LEMTGYAADEIIGNNCRFLQGPETDRQAVADVREAIDNRREFATEVLNYRKDGSTFWNAL
EEECCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHE
FVSPVFDDTGKLVYFFGSQLDVSRRRDAEDALRQAQKMEALGQLTGGIAHDFNNLLQVMS
EECCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
GHLEFIQMMVSNGNGSPDRIAVSAEHAAAAAAKAATLTQQLLAFSRKQKLRGRVVNLNGL
HHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHH
VSGMNNMAERALGGGITLRQALEERLWNCQIDTTQAEVALLNVLINARDAMANAERKEVM
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCHHHHEE
VQTQNVEITSHDLSMYHQLAPGRYVSIAVTDSGSGMPPEVVSRVMEPFFTTKEEGQGTGL
EEECCEEEEHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
GLSMVYGFVKQSGGTVRIYSEVGEGTTVRLYFPASSDYENALPSTKNRALDKGGNETILI
HHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCHHHCCCCCHHHHHCCCCCEEEEE
VEDKEDVAVVAKMFLEGAGYRALSASSGREAIEVLEQHPEVDALFTDLIMPGGMNGVVLA
EECCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEE
REARRMLPKIKVLLTTGYADASIQRTDVGGAEFDVVNKPYTQKELLKRIRMLLDGPTGVG
HHHHHHCCCEEEEEEECCCCCCEEECCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNDSGYGEPRAPLIGESQTLPVSKHRSDIFFAAVETTRMPMTVTDPYLPDNPIVFANRAF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEECCEE
LEMTGYAADEIIGNNCRFLQGPETDRQAVADVREAIDNRREFATEVLNYRKDGSTFWNAL
EEECCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHE
FVSPVFDDTGKLVYFFGSQLDVSRRRDAEDALRQAQKMEALGQLTGGIAHDFNNLLQVMS
EECCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
GHLEFIQMMVSNGNGSPDRIAVSAEHAAAAAAKAATLTQQLLAFSRKQKLRGRVVNLNGL
HHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHH
VSGMNNMAERALGGGITLRQALEERLWNCQIDTTQAEVALLNVLINARDAMANAERKEVM
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCHHHHEE
VQTQNVEITSHDLSMYHQLAPGRYVSIAVTDSGSGMPPEVVSRVMEPFFTTKEEGQGTGL
EEECCEEEEHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
GLSMVYGFVKQSGGTVRIYSEVGEGTTVRLYFPASSDYENALPSTKNRALDKGGNETILI
HHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCHHHCCCCCHHHHHCCCCCEEEEE
VEDKEDVAVVAKMFLEGAGYRALSASSGREAIEVLEQHPEVDALFTDLIMPGGMNGVVLA
EECCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEE
REARRMLPKIKVLLTTGYADASIQRTDVGGAEFDVVNKPYTQKELLKRIRMLLDGPTGVG
HHHHHHCCCEEEEEEECCCCCCEEECCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA