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The map label for this gene is aglA [H]

Identifier: 66767966

GI number: 66767966

Start: 1969222

End: 1970838

Strand: Direct

Name: aglA [H]

Synonym: XC_1642

Alternate gene names: 66767966

Gene position: 1969222-1970838 (Clockwise)

Preceding gene: 66767965

Following gene: 66767967

Centisome position: 38.25

GC content: 60.61

Gene sequence:

>1617_bases
ATGTCGCAGACACCATGGTGGCGCGGGGCCGTCATTTATCAGATTTATCCGCGTAGTTTTCTGGATTCCAATGGCGATGG
CGTAGGCGATCTGCCGGGCATCATTGCCAAGCTCGACTACATCGCCGGGCTGGGAGTAGATGCGATCTGGATTTCGCCTT
TTTTCAAGTCGCCGATGGCCGATTTCGGCTATGACATCGCAGACTATCGCGCGGTGGACCCGTTGTTCGGGTCGTTGGTC
GATTTCGATCGCTTGCTCGAAAAGGCACATGGCCTTGGGTTGAAAGTGATGATCGATCAGGTACTGAGCCATTCCTCGAT
CGCGCATGTGTGGTTTCAGGAGAGCCGACAGGACCGGAGCAACCCGAAGGCTGATTGGTACGTGTGGGCCGATCCGCGCG
AGGATGGAACGCCGCCGAACAACTGGCTGTCGTTGTTTGGTGGGGTCGCATGGCAGTGGGAGCCGCGGCGTGAGCAGTAC
TACCTGCACAACTTTCTGGTGGACCAGCCCGATCTCAATTTCCACAACGCCGAGGTGCAGCAGGCAACGCTCGATAACGT
GCGGTTCTGGCTCGATCGCGGTGTGGATGGGTTCCGTCTGGATGCGATCAACTTCTGCTTTCACGACGCGCAACTGCGCG
ATAACCCGGCCAAGCCGGCAGACAAGCGGGTGGGGCGCGGCTTCAGCGCGGACAATCCTTACGCCTACCAGTATCATTAC
TTCAACAACACGCAGCCGGAAAATCTAGCGTTCCTCGAGCGCCTGCGCGGGCTGCTGGATCTTTATCCGAATGCAGTGAG
CCTTGGCGAGATCTCGTCGGAAGATTCGCTGGCCACCACCGCCGAATACACCGCCCAGGGCCGCTTGCATATGGGCTACA
GCTTCGAGCTGCTGGTGCAGGATTACAGCGCTGCCTACATCCGCGACACCGTAAGCCGGCTCGAGGCCACCATGTTGGAG
GGCTGGCCATGCTGGGCCATTTCCAATCACGACGTAGTGCGCGCGGTAACGCGCTGGGGTGGGGCGCATGCGACGCCGGC
GTTCGCGCGGATGGTGGTGGCGCTGCTGTGTTCGCTGCGTGGATCGATCTGCCTATATCAGGGCGAAGAGCTCGGGCTCA
GTGAGGCAGAGGTGGCGTTCGAGGACCTGCAGGATCCGTATGGAATAACTTTCTGGCCGACCTTCAAGGGCCGGGATGGC
TGCCGTACGCCGATGCCATGGACCGACGCGCCATCTGCCGGATTCACCAGCGGCAAGCCTTGGCTGCCGTTAGCTGCGTC
GCATCGTGCCGCTGCTGTGAGCGTGCAACAGGATGATGCGCATTCCGTGTTGAGTGCAGTACGGGATTTTCTAGCTTGGC
GCAAAGAGATGCCGGCGCTGCGTGAGGGATCCATCGCTTTCTACGACACGGCCGAACCGGTGCTGATGTTCCGCCGCGAA
CACGCCGGCCAGGTTGTGCTGTTGGCATTCAATCTGTCCGCCGATCCTGCCGACCTGGCTTTGCCTGCAGGCGAGTGGGA
GCAGGTCGATGTACCTGGTGTCGAGCTTGGGGCGATGGATGGCGGACACCTAAGGCTGGCCGGGCATGCGGTCGTTGCTG
CTGTCGGTCGTGGCTGA

Upstream 100 bases:

>100_bases
TACGTATGCACGGACACGCTCAACCTCAGTTGCCCAGCTACGCTAACGCTCTTGGCTGGGCGCTCTTTCTTGCGCCCCCA
TTGGCCCGGGAGGGGCGTAT

Downstream 100 bases:

>100_bases
GTAAGCGCAGCTGAAACCTCTCGGCTTGGAGCAGCTATCAAAGCTACTGCGCAGCCGCCAGGCGGGCGCGGCCGGTGCTC
GGAATCGGCATGCACCCACG

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MSQTPWWRGAVIYQIYPRSFLDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMADFGYDIADYRAVDPLFGSLV
DFDRLLEKAHGLGLKVMIDQVLSHSSIAHVWFQESRQDRSNPKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQY
YLHNFLVDQPDLNFHNAEVQQATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
FNNTQPENLAFLERLRGLLDLYPNAVSLGEISSEDSLATTAEYTAQGRLHMGYSFELLVQDYSAAYIRDTVSRLEATMLE
GWPCWAISNHDVVRAVTRWGGAHATPAFARMVVALLCSLRGSICLYQGEELGLSEAEVAFEDLQDPYGITFWPTFKGRDG
CRTPMPWTDAPSAGFTSGKPWLPLAASHRAAAVSVQQDDAHSVLSAVRDFLAWRKEMPALREGSIAFYDTAEPVLMFRRE
HAGQVVLLAFNLSADPADLALPAGEWEQVDVPGVELGAMDGGHLRLAGHAVVAAVGRG

Sequences:

>Translated_538_residues
MSQTPWWRGAVIYQIYPRSFLDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMADFGYDIADYRAVDPLFGSLV
DFDRLLEKAHGLGLKVMIDQVLSHSSIAHVWFQESRQDRSNPKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQY
YLHNFLVDQPDLNFHNAEVQQATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
FNNTQPENLAFLERLRGLLDLYPNAVSLGEISSEDSLATTAEYTAQGRLHMGYSFELLVQDYSAAYIRDTVSRLEATMLE
GWPCWAISNHDVVRAVTRWGGAHATPAFARMVVALLCSLRGSICLYQGEELGLSEAEVAFEDLQDPYGITFWPTFKGRDG
CRTPMPWTDAPSAGFTSGKPWLPLAASHRAAAVSVQQDDAHSVLSAVRDFLAWRKEMPALREGSIAFYDTAEPVLMFRRE
HAGQVVLLAFNLSADPADLALPAGEWEQVDVPGVELGAMDGGHLRLAGHAVVAAVGRG
>Mature_537_residues
SQTPWWRGAVIYQIYPRSFLDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMADFGYDIADYRAVDPLFGSLVD
FDRLLEKAHGLGLKVMIDQVLSHSSIAHVWFQESRQDRSNPKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQYY
LHNFLVDQPDLNFHNAEVQQATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHYF
NNTQPENLAFLERLRGLLDLYPNAVSLGEISSEDSLATTAEYTAQGRLHMGYSFELLVQDYSAAYIRDTVSRLEATMLEG
WPCWAISNHDVVRAVTRWGGAHATPAFARMVVALLCSLRGSICLYQGEELGLSEAEVAFEDLQDPYGITFWPTFKGRDGC
RTPMPWTDAPSAGFTSGKPWLPLAASHRAAAVSVQQDDAHSVLSAVRDFLAWRKEMPALREGSIAFYDTAEPVLMFRREH
AGQVVLLAFNLSADPADLALPAGEWEQVDVPGVELGAMDGGHLRLAGHAVVAAVGRG

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=550, Percent_Identity=32.1818181818182, Blast_Score=273, Evalue=2e-73,
Organism=Escherichia coli, GI1790687, Length=548, Percent_Identity=35.948905109489, Blast_Score=305, Evalue=6e-84,
Organism=Escherichia coli, GI1786604, Length=497, Percent_Identity=24.3460764587525, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI32565753, Length=530, Percent_Identity=24.9056603773585, Blast_Score=118, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI25147709, Length=533, Percent_Identity=23.827392120075, Blast_Score=95, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6322245, Length=558, Percent_Identity=33.3333333333333, Blast_Score=285, Evalue=9e-78,
Organism=Saccharomyces cerevisiae, GI6319776, Length=557, Percent_Identity=34.4703770197487, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321731, Length=557, Percent_Identity=34.4703770197487, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321726, Length=557, Percent_Identity=32.6750448833034, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322241, Length=557, Percent_Identity=32.6750448833034, Blast_Score=267, Evalue=4e-72,
Organism=Saccharomyces cerevisiae, GI6322021, Length=557, Percent_Identity=32.6750448833034, Blast_Score=267, Evalue=4e-72,
Organism=Saccharomyces cerevisiae, GI6324416, Length=562, Percent_Identity=32.7402135231317, Blast_Score=265, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24583749, Length=515, Percent_Identity=37.4757281553398, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24583747, Length=515, Percent_Identity=37.4757281553398, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24583745, Length=561, Percent_Identity=36.1853832442068, Blast_Score=305, Evalue=5e-83,
Organism=Drosophila melanogaster, GI24586599, Length=520, Percent_Identity=36.3461538461538, Blast_Score=304, Evalue=9e-83,
Organism=Drosophila melanogaster, GI24586591, Length=509, Percent_Identity=37.328094302554, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24586587, Length=498, Percent_Identity=36.144578313253, Blast_Score=294, Evalue=9e-80,
Organism=Drosophila melanogaster, GI24586597, Length=507, Percent_Identity=36.2919132149901, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24586593, Length=503, Percent_Identity=36.3817097415507, Blast_Score=292, Evalue=4e-79,
Organism=Drosophila melanogaster, GI45549022, Length=526, Percent_Identity=32.6996197718631, Blast_Score=281, Evalue=1e-75,
Organism=Drosophila melanogaster, GI221330053, Length=506, Percent_Identity=33.9920948616601, Blast_Score=281, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24586589, Length=522, Percent_Identity=34.4827586206897, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI281360393, Length=451, Percent_Identity=33.2594235033259, Blast_Score=219, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 60028; Mature: 59897

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTPWWRGAVIYQIYPRSFLDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMA
CCCCCCCCCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHCCCHH
DFGYDIADYRAVDPLFGSLVDFDRLLEKAHGLGLKVMIDQVLSHSSIAHVWFQESRQDRS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCC
NPKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQYYLHNFLVDQPDLNFHNAEVQ
CCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCHHHEEHHHHEECCCCCCCCCCHHH
QATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
HHHHHHHHHHHHCCCCCEEEEHHHHHEECCHHCCCCCCCHHHHHCCCCCCCCCEEEEEEE
FNNTQPENLAFLERLRGLLDLYPNAVSLGEISSEDSLATTAEYTAQGRLHMGYSFELLVQ
CCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCCCEEEECCEEEEEEE
DYSAAYIRDTVSRLEATMLEGWPCWAISNHDVVRAVTRWGGAHATPAFARMVVALLCSLR
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GSICLYQGEELGLSEAEVAFEDLQDPYGITFWPTFKGRDGCRTPMPWTDAPSAGFTSGKP
CCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
WLPLAASHRAAAVSVQQDDAHSVLSAVRDFLAWRKEMPALREGSIAFYDTAEPVLMFRRE
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHCCCEEEECCCCHHHHHHHH
HAGQVVLLAFNLSADPADLALPAGEWEQVDVPGVELGAMDGGHLRLAGHAVVAAVGRG
CCCEEEEEEEECCCCCHHEECCCCCCCCCCCCCCEEECCCCCEEEEECCEEEEEECCC
>Mature Secondary Structure 
SQTPWWRGAVIYQIYPRSFLDSNGDGVGDLPGIIAKLDYIAGLGVDAIWISPFFKSPMA
CCCCCCCCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHCCCHH
DFGYDIADYRAVDPLFGSLVDFDRLLEKAHGLGLKVMIDQVLSHSSIAHVWFQESRQDRS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCC
NPKADWYVWADPREDGTPPNNWLSLFGGVAWQWEPRREQYYLHNFLVDQPDLNFHNAEVQ
CCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCHHHEEHHHHEECCCCCCCCCCHHH
QATLDNVRFWLDRGVDGFRLDAINFCFHDAQLRDNPAKPADKRVGRGFSADNPYAYQYHY
HHHHHHHHHHHHCCCCCEEEEHHHHHEECCHHCCCCCCCHHHHHCCCCCCCCCEEEEEEE
FNNTQPENLAFLERLRGLLDLYPNAVSLGEISSEDSLATTAEYTAQGRLHMGYSFELLVQ
CCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCCCEEEECCEEEEEEE
DYSAAYIRDTVSRLEATMLEGWPCWAISNHDVVRAVTRWGGAHATPAFARMVVALLCSLR
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GSICLYQGEELGLSEAEVAFEDLQDPYGITFWPTFKGRDGCRTPMPWTDAPSAGFTSGKP
CCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
WLPLAASHRAAAVSVQQDDAHSVLSAVRDFLAWRKEMPALREGSIAFYDTAEPVLMFRRE
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHCCCEEEECCCCHHHHHHHH
HAGQVVLLAFNLSADPADLALPAGEWEQVDVPGVELGAMDGGHLRLAGHAVVAAVGRG
CCCEEEEEEEECCCCCHHEECCCCCCCCCCCCCCEEECCCCCEEEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]