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The map label for this gene is nuoG [H]

Identifier: 66767919

GI number: 66767919

Start: 1913350

End: 1915584

Strand: Direct

Name: nuoG [H]

Synonym: XC_1595

Alternate gene names: 66767919

Gene position: 1913350-1915584 (Clockwise)

Preceding gene: 66767918

Following gene: 162017103

Centisome position: 37.16

GC content: 66.31

Gene sequence:

>2235_bases
ATGAGCGCCCAACCAGTGAACCCGAACGTGCCACCGGACCATGTCACCGTCGAGATCGACGGGCAGTCGCTGGTGGTGCC
GAAGGGCTCGATGATCATCCAGGCCGCCGACAAGGCCGGCATCCCGATCCCGCGCTTCTGTTACCACGAGAAGCTGCCGA
TTGCGGCCAACTGCCGCATGTGCCTGGTCGATGTTGAAAAGTCGCCCAAGCCGTCGCCTGCCTGCGCCACGCCGGTGATG
GACGGCATGAAGGTCACCACGCGCAGCGAAAAAGCGCTGAAGTACCAGCGCAGCGTGATGGAATTCCTGCTGATCAACCA
CCCGCTGGACTGCCCGATCTGCGATCAGGGCGGCGAGTGCGAATTGCAGGACGTCTCGCTTGGCTACGGCCGTTCGGTGA
GCCGCTTCAATGAGCGCAAGCGCGTGGTGCCGGACGAAGACATCGGCCCGCTGGTGGCGACCGAGATGACCCGCTGCATC
CAGTGCACGCGCTGCGTGCGCTTCACCGCCGATATCGCCGGAACCTACGAGCTGGGCGGTATGTATCGCGGTGAGAACCT
GCAGATCGGCACCTACGACGGCAAGCCGCTGACCACTGAAATTTCCGGCAACGTCATCGACGTTTGCCCGGTGGGCGCGC
TGACCAACAAGGTGTTCCAGTTCCGTGCGCGTCCGTGGGAACTGATGGCACGTGAATCGCTCGGTTATCACGATGCGATG
GGCTCCAACCTGTTCCTGCACGTGCGTCGCGGCGAAGTGCTGCGCACCGTGCCGCGCGAGAACGAAGCCGTCAACGAGTG
CTGGCTGTCCGATCGCGACCGTTATTCGCATCAGGGCCTGTACGCCGAAGACCGTGCGGTGAAGCCGCTCAAGAAGGTCA
ACGGTGAATGGACCGAAGTGAGCTGGGCCGAAGGCCTGGCCGCTGCGACGCAGATCCTGCGCGATAACGCCGGTGATCAG
CTCGGCGTGCTGGTGCACCCGGCCACCTCGAACGAAGAAGGCGCCTTGCTGGCGCGTCTGGCCGAGGGCCTGGGCAGCGG
CAACCTGGATCACCGCCTGCTCAACCGCGATTTCTCCGACGCCGCTGTTGCCGAAGCCTTTGCCACGCCGCTGGCCGAGA
TCGAACAGGCCGATGTCGTGGTGCTGTTCGGCACCAACGTGCGCCATGAGCTGCCGCTGCTGCATGCCCGCCTGCGCAAG
GCGAGCATCCAGAACCGCACCCAGATCCATTCGGTCAACCCGGTCGATTTCGATTTCGCCTTCACCCAGGCCAGCCGGAC
GGTGGTCTCGCCGACTCAGCTGGCTGGCGCGCTGGACGACGCCACGCTGCGTGATGCGGTCAAGGGCGCAAGCCGCGCCG
TGATCGTGGTCGGCGCATTGGCAGAAAATCATCCGCAGGCGGCGACGCTGCGTGCAGCGGCACGTGCCTTTGCAGCGGCA
ACCGGTGCGTCGCTGTGCCGGATCCCGCAGGGCGCCAACGCGGTCGGCCTGGTCTCGCAGGGCGTGTTGCCGACTGCGCG
GACAGTCGCCGGCATGTTTGCCGAGCCGCGTCAGGCGTATGTGGTGTACGGCATCGAACCCGGTCTGGATTTTGCCGATG
CGGCCGCTGCGCGCAGCGCGCTGGCCGGCGCGAAAGTCGTGGCTTTCAGCCAGTTCGCCTGTGCATCCACACGCGACGTG
GCCGATGTGATTTTGCCGATCGGCGCACTGCCGGAAATCGATGCGTCGCTGACCAATCTCGATGGCCGCGTGCAGACCGC
ACGTGCTGCGGGTCGGTTGCCGGTCGAGGCGCGTGAGGGCTGGCGCGTGCTGCGCGCACTGGGTGGTGAGCTGGGTCTGG
CTGGGTTCGAGTTCATCGACCTGGTCGGTCTGCGCGCCGGCATGCAGCAGCGCAGCGTGACTGCAGCGACGTCGGCGCAG
CCGGCTACTGCGAGCGAAGGTCTGGAAGTTGCAGCAACCGCTGCGATCTACCGCACCGATGCGGTGGTACGCCGCGCCGC
CGCACTGCAGTCGCACCCGCTCAACATCGCCCCGTGTGTGGCGATGCACCCGGAGCAGGCCGCGCAGCTGCAGGTCGCTG
CCGGGCAAGTCGTCAAGGTTGGCACCGACGCGGGCAGGGCGACCTTGCCGGTGGTGCTGGACAAGCGCGTCGCACCGGGC
ACGGTGTGGATCGAATCCGGCCATGGCGCAACCGCGCCGTTGGGTGCCGGTCGGGTAACGGTGGTGGCTGCATGA

Upstream 100 bases:

>100_bases
CATGGCCGATCCAGGGCTTCCTGCGCCAGTTCTGGGACGAATTCGAGTACTACATCGTCAACGGTCGTTCGATCGTCGAC
ACGCATGTCGGAGTGGCCGC

Downstream 100 bases:

>100_bases
ACGAGTTGCTGTTGAACGTGGTCGACCCCCTGCACCAGTGGTTCCTCGGACTGGGCGATGGCGGCGTGTTGCTGTGGACC
GTGCTGAAGATCCTGCTGAT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 744; Mature: 743

Protein sequence:

>744_residues
MSAQPVNPNVPPDHVTVEIDGQSLVVPKGSMIIQAADKAGIPIPRFCYHEKLPIAANCRMCLVDVEKSPKPSPACATPVM
DGMKVTTRSEKALKYQRSVMEFLLINHPLDCPICDQGGECELQDVSLGYGRSVSRFNERKRVVPDEDIGPLVATEMTRCI
QCTRCVRFTADIAGTYELGGMYRGENLQIGTYDGKPLTTEISGNVIDVCPVGALTNKVFQFRARPWELMARESLGYHDAM
GSNLFLHVRRGEVLRTVPRENEAVNECWLSDRDRYSHQGLYAEDRAVKPLKKVNGEWTEVSWAEGLAAATQILRDNAGDQ
LGVLVHPATSNEEGALLARLAEGLGSGNLDHRLLNRDFSDAAVAEAFATPLAEIEQADVVVLFGTNVRHELPLLHARLRK
ASIQNRTQIHSVNPVDFDFAFTQASRTVVSPTQLAGALDDATLRDAVKGASRAVIVVGALAENHPQAATLRAAARAFAAA
TGASLCRIPQGANAVGLVSQGVLPTARTVAGMFAEPRQAYVVYGIEPGLDFADAAAARSALAGAKVVAFSQFACASTRDV
ADVILPIGALPEIDASLTNLDGRVQTARAAGRLPVEAREGWRVLRALGGELGLAGFEFIDLVGLRAGMQQRSVTAATSAQ
PATASEGLEVAATAAIYRTDAVVRRAAALQSHPLNIAPCVAMHPEQAAQLQVAAGQVVKVGTDAGRATLPVVLDKRVAPG
TVWIESGHGATAPLGAGRVTVVAA

Sequences:

>Translated_744_residues
MSAQPVNPNVPPDHVTVEIDGQSLVVPKGSMIIQAADKAGIPIPRFCYHEKLPIAANCRMCLVDVEKSPKPSPACATPVM
DGMKVTTRSEKALKYQRSVMEFLLINHPLDCPICDQGGECELQDVSLGYGRSVSRFNERKRVVPDEDIGPLVATEMTRCI
QCTRCVRFTADIAGTYELGGMYRGENLQIGTYDGKPLTTEISGNVIDVCPVGALTNKVFQFRARPWELMARESLGYHDAM
GSNLFLHVRRGEVLRTVPRENEAVNECWLSDRDRYSHQGLYAEDRAVKPLKKVNGEWTEVSWAEGLAAATQILRDNAGDQ
LGVLVHPATSNEEGALLARLAEGLGSGNLDHRLLNRDFSDAAVAEAFATPLAEIEQADVVVLFGTNVRHELPLLHARLRK
ASIQNRTQIHSVNPVDFDFAFTQASRTVVSPTQLAGALDDATLRDAVKGASRAVIVVGALAENHPQAATLRAAARAFAAA
TGASLCRIPQGANAVGLVSQGVLPTARTVAGMFAEPRQAYVVYGIEPGLDFADAAAARSALAGAKVVAFSQFACASTRDV
ADVILPIGALPEIDASLTNLDGRVQTARAAGRLPVEAREGWRVLRALGGELGLAGFEFIDLVGLRAGMQQRSVTAATSAQ
PATASEGLEVAATAAIYRTDAVVRRAAALQSHPLNIAPCVAMHPEQAAQLQVAAGQVVKVGTDAGRATLPVVLDKRVAPG
TVWIESGHGATAPLGAGRVTVVAA
>Mature_743_residues
SAQPVNPNVPPDHVTVEIDGQSLVVPKGSMIIQAADKAGIPIPRFCYHEKLPIAANCRMCLVDVEKSPKPSPACATPVMD
GMKVTTRSEKALKYQRSVMEFLLINHPLDCPICDQGGECELQDVSLGYGRSVSRFNERKRVVPDEDIGPLVATEMTRCIQ
CTRCVRFTADIAGTYELGGMYRGENLQIGTYDGKPLTTEISGNVIDVCPVGALTNKVFQFRARPWELMARESLGYHDAMG
SNLFLHVRRGEVLRTVPRENEAVNECWLSDRDRYSHQGLYAEDRAVKPLKKVNGEWTEVSWAEGLAAATQILRDNAGDQL
GVLVHPATSNEEGALLARLAEGLGSGNLDHRLLNRDFSDAAVAEAFATPLAEIEQADVVVLFGTNVRHELPLLHARLRKA
SIQNRTQIHSVNPVDFDFAFTQASRTVVSPTQLAGALDDATLRDAVKGASRAVIVVGALAENHPQAATLRAAARAFAAAT
GASLCRIPQGANAVGLVSQGVLPTARTVAGMFAEPRQAYVVYGIEPGLDFADAAAARSALAGAKVVAFSQFACASTRDVA
DVILPIGALPEIDASLTNLDGRVQTARAAGRLPVEAREGWRVLRALGGELGLAGFEFIDLVGLRAGMQQRSVTAATSAQP
ATASEGLEVAATAAIYRTDAVVRRAAALQSHPLNIAPCVAMHPEQAAQLQVAAGQVVKVGTDAGRATLPVVLDKRVAPGT
VWIESGHGATAPLGAGRVTVVAA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=620, Percent_Identity=39.0322580645161, Blast_Score=407, Evalue=1e-113,
Organism=Escherichia coli, GI145693161, Length=384, Percent_Identity=29.9479166666667, Blast_Score=204, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17565758, Length=638, Percent_Identity=36.3636363636364, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI32566231, Length=593, Percent_Identity=37.0994940978078, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI193209088, Length=257, Percent_Identity=54.863813229572, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24640559, Length=638, Percent_Identity=40.1253918495298, Blast_Score=400, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24640557, Length=638, Percent_Identity=40.1253918495298, Blast_Score=400, Evalue=1e-111,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 79084; Mature: 78953

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQPVNPNVPPDHVTVEIDGQSLVVPKGSMIIQAADKAGIPIPRFCYHEKLPIAANCRM
CCCCCCCCCCCCCEEEEEECCCEEEECCCCEEEEECCCCCCCCCHHHHCCCCCEECCCEE
CLVDVEKSPKPSPACATPVMDGMKVTTRSEKALKYQRSVMEFLLINHPLDCPICDQGGEC
EEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ELQDVSLGYGRSVSRFNERKRVVPDEDIGPLVATEMTRCIQCTRCVRFTADIAGTYELGG
EEEEECCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
MYRGENLQIGTYDGKPLTTEISGNVIDVCPVGALTNKVFQFRARPWELMARESLGYHDAM
EEECCCEEEECCCCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHCC
GSNLFLHVRRGEVLRTVPRENEAVNECWLSDRDRYSHQGLYAEDRAVKPLKKVNGEWTEV
CCCEEEEEECCCHHHCCCCCCHHHHHHHCCCCCCHHCCCCCCCCHHHCHHHHCCCCEEEE
SWAEGLAAATQILRDNAGDQLGVLVHPATSNEEGALLARLAEGLGSGNLDHRLLNRDFSD
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCH
AAVAEAFATPLAEIEQADVVVLFGTNVRHELPLLHARLRKASIQNRTQIHSVNPVDFDFA
HHHHHHHHCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEE
FTQASRTVVSPTQLAGALDDATLRDAVKGASRAVIVVGALAENHPQAATLRAAARAFAAA
EHHCCCEEECHHHHHHCCCHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
TGASLCRIPQGANAVGLVSQGVLPTARTVAGMFAEPRQAYVVYGIEPGLDFADAAAARSA
CCCHHEECCCCCCEEEHHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHH
LAGAKVVAFSQFACASTRDVADVILPIGALPEIDASLTNLDGRVQTARAAGRLPVEAREG
HCCCCEEEEHHHHCCCCCHHHHHHHCCCCCCCCCCHHHCCCCCEEHHHHCCCCCCHHHHH
WRVLRALGGELGLAGFEFIDLVGLRAGMQQRSVTAATSAQPATASEGLEVAATAAIYRTD
HHHHHHHCCCCCCCHHHHHHHHHHHHCCHHCCEEECCCCCCCCCCCCCEEHHHHHHHHHH
AVVRRAAALQSHPLNIAPCVAMHPEQAAQLQVAAGQVVKVGTDAGRATLPVVLDKRVAPG
HHHHHHHHHHCCCCCEECEEEECCHHHHEEEEECCCEEEEECCCCCEEECEEECCCCCCC
TVWIESGHGATAPLGAGRVTVVAA
EEEEECCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SAQPVNPNVPPDHVTVEIDGQSLVVPKGSMIIQAADKAGIPIPRFCYHEKLPIAANCRM
CCCCCCCCCCCCEEEEEECCCEEEECCCCEEEEECCCCCCCCCHHHHCCCCCEECCCEE
CLVDVEKSPKPSPACATPVMDGMKVTTRSEKALKYQRSVMEFLLINHPLDCPICDQGGEC
EEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ELQDVSLGYGRSVSRFNERKRVVPDEDIGPLVATEMTRCIQCTRCVRFTADIAGTYELGG
EEEEECCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
MYRGENLQIGTYDGKPLTTEISGNVIDVCPVGALTNKVFQFRARPWELMARESLGYHDAM
EEECCCEEEECCCCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHCC
GSNLFLHVRRGEVLRTVPRENEAVNECWLSDRDRYSHQGLYAEDRAVKPLKKVNGEWTEV
CCCEEEEEECCCHHHCCCCCCHHHHHHHCCCCCCHHCCCCCCCCHHHCHHHHCCCCEEEE
SWAEGLAAATQILRDNAGDQLGVLVHPATSNEEGALLARLAEGLGSGNLDHRLLNRDFSD
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCH
AAVAEAFATPLAEIEQADVVVLFGTNVRHELPLLHARLRKASIQNRTQIHSVNPVDFDFA
HHHHHHHHCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEE
FTQASRTVVSPTQLAGALDDATLRDAVKGASRAVIVVGALAENHPQAATLRAAARAFAAA
EHHCCCEEECHHHHHHCCCHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
TGASLCRIPQGANAVGLVSQGVLPTARTVAGMFAEPRQAYVVYGIEPGLDFADAAAARSA
CCCHHEECCCCCCEEEHHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHH
LAGAKVVAFSQFACASTRDVADVILPIGALPEIDASLTNLDGRVQTARAAGRLPVEAREG
HCCCCEEEEHHHHCCCCCHHHHHHHCCCCCCCCCCHHHCCCCCEEHHHHCCCCCCHHHHH
WRVLRALGGELGLAGFEFIDLVGLRAGMQQRSVTAATSAQPATASEGLEVAATAAIYRTD
HHHHHHHCCCCCCCHHHHHHHHHHHHCCHHCCEEECCCCCCCCCCCCCEEHHHHHHHHHH
AVVRRAAALQSHPLNIAPCVAMHPEQAAQLQVAAGQVVKVGTDAGRATLPVVLDKRVAPG
HHHHHHHHHHCCCCCEECEEEECCHHHHEEEEECCCEEEEECCCCCEEECEEECCCCCCC
TVWIESGHGATAPLGAGRVTVVAA
EEEEECCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]