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The map label for this gene is nuoB [H]

Identifier: 66767914

GI number: 66767914

Start: 1908823

End: 1909398

Strand: Direct

Name: nuoB [H]

Synonym: XC_1590

Alternate gene names: 66767914

Gene position: 1908823-1909398 (Clockwise)

Preceding gene: 66767913

Following gene: 66767915

Centisome position: 37.07

GC content: 63.19

Gene sequence:

>576_bases
GTGGAAGAAGGGAGCGCTGGAATGGGAGTGATTCAGACCCTGGATCGTCTGATGACCAACCCGATGCCGGAAGGCCGGGT
CGAAGACATCCTGCGCCCGGAAGGCGAAAACCCGTTGCTCGAAAAGGGCTACGTGACCACCAGCGTCGATGCGCTGTTGA
ACTGGGCGCGTACAGGTTCGATGTGGCCGATGACCTTTGGTCTGGCCTGCTGTGCAGTCGAGATGATGCACGCCGGTGCA
GCGCGCCTGGACCTGGACCGCTACGGCGTGGTGTTCCGCCCGTCGCCGCGCCAGTCCGACGTGATGATCGTCGCCGGCAC
TCTGGTCAACAAGATGGCGCCGGCATTGCGCAAGGTCTACGACCAGATGCCCGACCCGAAGTGGGTCATCTCGATGGGCA
GCTGCGCCAACGGCGGCGGCTACTATCACTATTCGTATTCGGTGGTGCGCGGTTGCGATCGCATCGTGCCGGTGGACATC
TATGTCCCGGGCTGCCCGCCGACCGCCGAGGCGCTGGTCTACGGCATCTTGCAGCTGCAGAAGAAAATCTGGCGCACCCA
GACGATCGCACGCTGA

Upstream 100 bases:

>100_bases
TCATCGTGCCGTGGACACAGGTGTTCATGGAGATCGGCGCACGCTCGCTGGTCACCATGGGCCTGTTCGTCGGCATGTTG
TTCCTCGGTTTTATCTACGT

Downstream 100 bases:

>100_bases
CACCCGTCTTCTCCTACCGAGAGCAGCCAAGCCCCCATGGCAGAGCAAGCATCTTCCTTCACTGACCGACTAGCGGCGCG
TTTCGCCGGTGCGCAGATCT

Product: NADH dehydrogenase subunit B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B; NDH-1 subunit B [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MEEGSAGMGVIQTLDRLMTNPMPEGRVEDILRPEGENPLLEKGYVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGA
ARLDLDRYGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDI
YVPGCPPTAEALVYGILQLQKKIWRTQTIAR

Sequences:

>Translated_191_residues
MEEGSAGMGVIQTLDRLMTNPMPEGRVEDILRPEGENPLLEKGYVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGA
ARLDLDRYGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDI
YVPGCPPTAEALVYGILQLQKKIWRTQTIAR
>Mature_191_residues
MEEGSAGMGVIQTLDRLMTNPMPEGRVEDILRPEGENPLLEKGYVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGA
ARLDLDRYGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDI
YVPGCPPTAEALVYGILQLQKKIWRTQTIAR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI187281616, Length=158, Percent_Identity=75.3164556962025, Blast_Score=257, Evalue=4e-69,
Organism=Escherichia coli, GI1788624, Length=170, Percent_Identity=47.0588235294118, Blast_Score=160, Evalue=3e-41,
Organism=Escherichia coli, GI1789074, Length=122, Percent_Identity=41.8032786885246, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1788834, Length=122, Percent_Identity=40.1639344262295, Blast_Score=94, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17509685, Length=151, Percent_Identity=72.1854304635762, Blast_Score=246, Evalue=7e-66,
Organism=Drosophila melanogaster, GI18859983, Length=173, Percent_Identity=70.5202312138728, Blast_Score=260, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24642371, Length=173, Percent_Identity=70.5202312138728, Blast_Score=260, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24651058, Length=155, Percent_Identity=76.1290322580645, Blast_Score=255, Evalue=2e-68,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 21090; Mature: 21090

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS01150 COMPLEX1_20K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEGSAGMGVIQTLDRLMTNPMPEGRVEDILRPEGENPLLEKGYVTTSVDALLNWARTGS
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
MWPMTFGLACCAVEMMHAGAARLDLDRYGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVY
CCHHHHHHHHHHHHHHHCCCHHEEHHHCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHHH
DQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALVYGILQLQ
HHCCCCCEEEEECCCCCCCCEEEEHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
KKIWRTQTIAR
HHHHHHHHCCC
>Mature Secondary Structure
MEEGSAGMGVIQTLDRLMTNPMPEGRVEDILRPEGENPLLEKGYVTTSVDALLNWARTGS
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
MWPMTFGLACCAVEMMHAGAARLDLDRYGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVY
CCHHHHHHHHHHHHHHHCCCHHEEHHHCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHHH
DQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALVYGILQLQ
HHCCCCCEEEEECCCCCCCCEEEEHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
KKIWRTQTIAR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA