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The map label for this gene is pcbC [H]

Identifier: 66767904

GI number: 66767904

Start: 1899023

End: 1899961

Strand: Direct

Name: pcbC [H]

Synonym: XC_1580

Alternate gene names: 66767904

Gene position: 1899023-1899961 (Clockwise)

Preceding gene: 66767903

Following gene: 66767905

Centisome position: 36.88

GC content: 63.37

Gene sequence:

>939_bases
ATGAGCGCGCGCATCCCCACCCTGGACATCACCCGTTTCGACAGCGACCGCGAGGCCTTTGTCGCCGAGCTCGGTGCCGC
TTATCGGCAATGGGGCTTTGCCGGTATCCGCAATCACGGCATTGCGCAGTCCGACATCGACGCCGCCTACGAGGTGTTCA
AGGCATTTTTCGCGCTGCCCGACGAGGTCAAGCGCAGCTACCACGTGCCCGGCAGTGGCGGCGCGCGCGGCTATACCGCG
TTCGGTGTGGAAACCGCCAAGGACTCCAAGCATTTCGATTTGAAAGAGTTCTGGCACATCGGCCGCGAGATCCCGGACGA
TTCGCCGTACCGCGCGGTGATGGCGCCCAATCTGTGGCCGACCGAAGTGCCGGGCTTCCGCGAACGTGGCTACCACCTGT
ATCAGCAGTTGGATCAGCTGGGCTCGCGCGTGTTGTCGGCGCTGGCGCTGCACATCGGCCTGCCGCAGGACTACTTCGCC
GACAAGACCGATCACGGCAATTCGATCCTGCGCCCGATCCATTACCCGCCGATCACCAGCGACGACATCCCGAATGTACG
CGCCGGTGCGCACGGCGACATCAATTTCATCACCTTGCTGGTGGGCGCCAGTGCCGCCGGCCTGGAAGTGCGTTCCAACG
AAGGCGAGTGGGTGCCGTTCACTGCGGACGCCGACACCATCGTGGTCAATATCGGCGACATGCTGCAGCGCCTGACTAAC
CATGTGTACCCGTCCACCATCCACCGCGTGGTCAATCCGCCGGGAGAGGAAGCGCGCAAGCCGCGCTATTCGGTGCCGTT
CTTCCTGCACCCGAACCCGGATTTCCTGATCGACGTGTTGCCGTCCTGCATCAGCGCCGACAACCCCAGCCGCTATCCCG
AGCCGATCACCGCACACGGGTTTCTGGAAGAGCGCCTGCGCGAGATCAAGCTCAAGTAA

Upstream 100 bases:

>100_bases
GCGTCTGCGTGGTCTTCGCCAAGGCCGCGACGTTTTATGTGCTGTATCGCCTGCTGTCCTGAGCGGCAGGTCTTCTTTCA
TTCTTGAGCAAGACATCCGT

Downstream 100 bases:

>100_bases
GCCGAACGGACCCAAGCGCAGCCTATGGCCGCGCTCGCAACATGGCGGATGACGCTCGCCACAGTTTGCTTGATGAACGT
TCGCTCGCGTCCGGTTAAAG

Product: oxidoreductase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSARIPTLDITRFDSDREAFVAELGAAYRQWGFAGIRNHGIAQSDIDAAYEVFKAFFALPDEVKRSYHVPGSGGARGYTA
FGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMAPNLWPTEVPGFRERGYHLYQQLDQLGSRVLSALALHIGLPQDYFA
DKTDHGNSILRPIHYPPITSDDIPNVRAGAHGDINFITLLVGASAAGLEVRSNEGEWVPFTADADTIVVNIGDMLQRLTN
HVYPSTIHRVVNPPGEEARKPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHGFLEERLREIKLK

Sequences:

>Translated_312_residues
MSARIPTLDITRFDSDREAFVAELGAAYRQWGFAGIRNHGIAQSDIDAAYEVFKAFFALPDEVKRSYHVPGSGGARGYTA
FGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMAPNLWPTEVPGFRERGYHLYQQLDQLGSRVLSALALHIGLPQDYFA
DKTDHGNSILRPIHYPPITSDDIPNVRAGAHGDINFITLLVGASAAGLEVRSNEGEWVPFTADADTIVVNIGDMLQRLTN
HVYPSTIHRVVNPPGEEARKPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHGFLEERLREIKLK
>Mature_311_residues
SARIPTLDITRFDSDREAFVAELGAAYRQWGFAGIRNHGIAQSDIDAAYEVFKAFFALPDEVKRSYHVPGSGGARGYTAF
GVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMAPNLWPTEVPGFRERGYHLYQQLDQLGSRVLSALALHIGLPQDYFAD
KTDHGNSILRPIHYPPITSDDIPNVRAGAHGDINFITLLVGASAAGLEVRSNEGEWVPFTADADTIVVNIGDMLQRLTNH
VYPSTIHRVVNPPGEEARKPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHGFLEERLREIKLK

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI85816264, Length=287, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI28572124, Length=269, Percent_Identity=30.4832713754647, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24649039, Length=351, Percent_Identity=26.2108262108262, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 34875; Mature: 34743

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARIPTLDITRFDSDREAFVAELGAAYRQWGFAGIRNHGIAQSDIDAAYEVFKAFFALP
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCC
DEVKRSYHVPGSGGARGYTAFGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMAPNLWP
HHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCC
TEVPGFRERGYHLYQQLDQLGSRVLSALALHIGLPQDYFADKTDHGNSILRPIHYPPITS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCC
DDIPNVRAGAHGDINFITLLVGASAAGLEVRSNEGEWVPFTADADTIVVNIGDMLQRLTN
CCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCEEEEECCCCEEEEEHHHHHHHHHH
HVYPSTIHRVVNPPGEEARKPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHG
CCCHHHHHHHCCCCCHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHH
FLEERLREIKLK
HHHHHHHHHCCC
>Mature Secondary Structure 
SARIPTLDITRFDSDREAFVAELGAAYRQWGFAGIRNHGIAQSDIDAAYEVFKAFFALP
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCC
DEVKRSYHVPGSGGARGYTAFGVETAKDSKHFDLKEFWHIGREIPDDSPYRAVMAPNLWP
HHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCC
TEVPGFRERGYHLYQQLDQLGSRVLSALALHIGLPQDYFADKTDHGNSILRPIHYPPITS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCC
DDIPNVRAGAHGDINFITLLVGASAAGLEVRSNEGEWVPFTADADTIVVNIGDMLQRLTN
CCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCEEEEECCCCEEEEEHHHHHHHHHH
HVYPSTIHRVVNPPGEEARKPRYSVPFFLHPNPDFLIDVLPSCISADNPSRYPEPITAHG
CCCHHHHHHHCCCCCHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHH
FLEERLREIKLK
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3216857; 8639682 [H]