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The map label for this gene is asd [H]

Identifier: 66767893

GI number: 66767893

Start: 1887019

End: 1888044

Strand: Direct

Name: asd [H]

Synonym: XC_1569

Alternate gene names: 66767893

Gene position: 1887019-1888044 (Clockwise)

Preceding gene: 66767892

Following gene: 66767894

Centisome position: 36.65

GC content: 63.84

Gene sequence:

>1026_bases
ATGAGCAACGAAACCCGTCGTTTCAACGTCGCCGTCGTGGGCGCCACCGGCGCTGTCGGCGAAACCATGTTGAGCATCCT
GGCCGAACGTCAGTTCCCGGTCGCCACTTTGTATGCACTGGCATCGGCGCGCTCGGCGGGCGGGCAGGTCGAGTTCAACG
GCGGCAAGGTCGACGTGCTGGACCTGGCCGACTTCGACCCCACCGGCGTGGACATCGCGCTGTTTTCCGCAGGCGGCAGT
GTCTCCAAGGAATACGGCCCCAAGTTCGCCGCGGCCGGTGCGGTGGTAATCGATAATTCCTCGGCGTTCCGCTACGACGA
CGATGTGCCGCTGGTGGTGTCCGAGGTCAATCCCGAAGCGCTGAAGCAGCGCCCGCGCGGGATCATTGCCAACCCCAATT
GCTCGACCATGCAGATGCTGGTGGCGCTGGGCCCGATCCACCGCAAGTACGGCATCGAGCGCATCAACGTGGCGACCTAT
CAGTCGGTGTCCGGCGGCGGCCGTTCGGCGATGGAGGAACTGGGCAAGCAGACTAGCGAATTGCTGAGCTTCCAGCAGAT
CGACCCGCAGCGCTTCCCGGTGCAGATCGCTTTCAACCTGATTCCGCACATCGACGATTTCCAGGACAACGGCTACACCA
AGGAAGAGATGAAGCTGGTCTGGGAGACCCGCAAGATCCTCGGTGACGAAAACATCCAGGTGAATCCCACCGCGGTGCGC
GTGCCGGTGTTCTACGGGCATTCGGAAGCGGTGGCCATCGAGACCCGCGAAAAGATCACCGTGGCCGAAGCCCGCGCATT
GCTGGCAGCCTCGCCGGGTGTGGAAGTGGTGGACGAGCACAAGGCCGGCGGCTACCCGACCCCGGTGACGCATGCCTCCG
GCCAGGACGCGGTATTCGTTGGCCGCATCCGCGAGGATCTCTCGCACCCGCGCGGCCTGAATCTGTGGATCGTCTCCGAC
AATATCCGCAAGGGCGCCGCACTCAATGCCGTGCAGCTGGCCGAATTGGTCGCACAGGAAGGCTGA

Upstream 100 bases:

>100_bases
TGCGACCAAACGATAGGGAACCTCCGCGGCCAGCTTTGGAGGTTCCCCGAACCCAGCGCGCAGTGCTCCCTTTCTTTCCC
CTTTCGATAAAGACATTCTC

Downstream 100 bases:

>100_bases
GCCTGCAGCGCCGTAGGAGCGCGCTCGCGCGCGATGAGGCTTTCCCAGTAACGCCCCATCGCGCACAAGTGCGCTCCTAC
GTTCATTCGTGTTGATGCTG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSNETRRFNVAVVGATGAVGETMLSILAERQFPVATLYALASARSAGGQVEFNGGKVDVLDLADFDPTGVDIALFSAGGS
VSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEALKQRPRGIIANPNCSTMQMLVALGPIHRKYGIERINVATY
QSVSGGGRSAMEELGKQTSELLSFQQIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDENIQVNPTAVR
VPVFYGHSEAVAIETREKITVAEARALLAASPGVEVVDEHKAGGYPTPVTHASGQDAVFVGRIREDLSHPRGLNLWIVSD
NIRKGAALNAVQLAELVAQEG

Sequences:

>Translated_341_residues
MSNETRRFNVAVVGATGAVGETMLSILAERQFPVATLYALASARSAGGQVEFNGGKVDVLDLADFDPTGVDIALFSAGGS
VSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEALKQRPRGIIANPNCSTMQMLVALGPIHRKYGIERINVATY
QSVSGGGRSAMEELGKQTSELLSFQQIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDENIQVNPTAVR
VPVFYGHSEAVAIETREKITVAEARALLAASPGVEVVDEHKAGGYPTPVTHASGQDAVFVGRIREDLSHPRGLNLWIVSD
NIRKGAALNAVQLAELVAQEG
>Mature_340_residues
SNETRRFNVAVVGATGAVGETMLSILAERQFPVATLYALASARSAGGQVEFNGGKVDVLDLADFDPTGVDIALFSAGGSV
SKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEALKQRPRGIIANPNCSTMQMLVALGPIHRKYGIERINVATYQ
SVSGGGRSAMEELGKQTSELLSFQQIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDENIQVNPTAVRV
PVFYGHSEAVAIETREKITVAEARALLAASPGVEVVDEHKAGGYPTPVTHASGQDAVFVGRIREDLSHPRGLNLWIVSDN
IRKGAALNAVQLAELVAQEG

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=335, Percent_Identity=41.1940298507463, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1789841, Length=356, Percent_Identity=29.2134831460674, Blast_Score=108, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320362, Length=391, Percent_Identity=29.156010230179, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36660; Mature: 36529

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNETRRFNVAVVGATGAVGETMLSILAERQFPVATLYALASARSAGGQVEFNGGKVDVL
CCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCEEEEE
DLADFDPTGVDIALFSAGGSVSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEA
EECCCCCCCCEEEEEECCCCCCHHHCCCCHHCCEEEEECCCCEEECCCCCEEEECCCHHH
LKQRPRGIIANPNCSTMQMLVALGPIHRKYGIERINVATYQSVSGGGRSAMEELGKQTSE
HHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
LLSFQQIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDENIQVNPTAVR
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEE
VPVFYGHSEAVAIETREKITVAEARALLAASPGVEVVDEHKAGGYPTPVTHASGQDAVFV
EEEEECCCCEEEEECCCEEEHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEEE
GRIREDLSHPRGLNLWIVSDNIRKGAALNAVQLAELVAQEG
EHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SNETRRFNVAVVGATGAVGETMLSILAERQFPVATLYALASARSAGGQVEFNGGKVDVL
CCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCEEEEE
DLADFDPTGVDIALFSAGGSVSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEA
EECCCCCCCCEEEEEECCCCCCHHHCCCCHHCCEEEEECCCCEEECCCCCEEEECCCHHH
LKQRPRGIIANPNCSTMQMLVALGPIHRKYGIERINVATYQSVSGGGRSAMEELGKQTSE
HHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
LLSFQQIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDENIQVNPTAVR
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEE
VPVFYGHSEAVAIETREKITVAEARALLAASPGVEVVDEHKAGGYPTPVTHASGQDAVFV
EEEEECCCCEEEEECCCEEEHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEEE
GRIREDLSHPRGLNLWIVSDNIRKGAALNAVQLAELVAQEG
EHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9573067 [H]