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The map label for this gene is aroC [H]

Identifier: 66767891

GI number: 66767891

Start: 1884780

End: 1885883

Strand: Direct

Name: aroC [H]

Synonym: XC_1567

Alternate gene names: 66767891

Gene position: 1884780-1885883 (Clockwise)

Preceding gene: 66767890

Following gene: 66767892

Centisome position: 36.61

GC content: 66.67

Gene sequence:

>1104_bases
ATGGGCAGTAACAGTTTTGGCCGCTTGTTCACGGTCACCACTTTCGGCGAATCGCATGGGCCGGCGATCGGCTGCGTCAT
CGACGGTTGCCCTCCCGGCCTGGAGATCGCGCCGGAAGAGTTCACCCACGACCTGCAGCGGCGTGCCACCGGCAAGAGCC
GGCATACCTCCGCGCGCCGCGAGGCCGACGAGATCGAAATCCTGTCCGGCGTCTACGAGGGCCGCACAACCGGCACGCCG
ATCGGGCTGCTGATCCGCAACACCGATCAGCGCAGCAAGGACTACACCAACATCGCCCAGCAGTTCCGCCCCGGGCATGC
TGATTACACCTATTGGCAGAAGTACGGCATCCGCGACCCGCGTGGTGGCGGGCGCTCGTCCGCGCGCGAAACTACCATGC
GCGTGGCCGCCGGCGTGATCGCCAAAAAGTGGCTCAAGCAGCGCTACGGCGTGCTGGTGCGCGGTTTCCTGTCGCAGTTG
GGCGAGATCCGCCCGAGCGGGTTTGATTGGGATGCGGTGGAAGACAACCCGTTCTTCTGGCCGCATGCGGCGCAGGTGCC
GGAGCTGGAAACCTATATGGATGCGCTGCGCAAGTCCGGTGACTCGGTCGGTGCGCGCGTGGACGTGGTGGCCGGTGGCG
TGCCGCCGGGATGGGGCGAGCCGATCTACGGCAAGCTTGATTCCGAACTGGCCGCGGCGCTGATGAGCATCAATGCGGTC
AAGGGTGTGGAGATTGGCGATGGCTTCGCCAGTGCCGCGCAGAAGGGCACCGAACACCGCGATCTGATCACCCCGGAAGG
CTTCCTCAGCAATCACGCCGGCGGCATTCTCGGCGGCATTTCCACCGGGCAGGCGGTCACCGCCTCGATGGTGCTCAAGC
CGACCTCCAGCCTGCGGCTGCCCGGCGCCACCGTGGATGCCGACGGCGCCGTGGTGGATGTCATCACCACCGGGCGCCAT
GACCCGTGCGTGGGCATCCGTGCCACGCCGATCGCCGAGGCCATGATGGCGCTGGTATTGATGGACCAGGCCTTGCGCCA
TCGCGCCCAATGCGGCGACGTGGGCGAGGTGTCGCCGCTGATTCCCGGTCAGGCCGATGTCTGA

Upstream 100 bases:

>100_bases
AGTGGTGTGCTGGCAGTGGCGCCGATGCTGGTCGCCGCACGTCACCTGCCGCGCATGCTGCACGCGCTGCAGCCTGCAGA
GATGTTGAAAGGATGCCGTC

Downstream 100 bases:

>100_bases
CACCGCGCGCCCCAAGGTCTGGGTCAGCCAGCCGTTGTTCGACGATGTGGTCGAACAGCTGGGCGCGCATTTCGAACTGG
TCACCACCGCGCAGGTCACG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MGSNSFGRLFTVTTFGESHGPAIGCVIDGCPPGLEIAPEEFTHDLQRRATGKSRHTSARREADEIEILSGVYEGRTTGTP
IGLLIRNTDQRSKDYTNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQL
GEIRPSGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPPGWGEPIYGKLDSELAAALMSINAV
KGVEIGDGFASAAQKGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGAVVDVITTGRH
DPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPLIPGQADV

Sequences:

>Translated_367_residues
MGSNSFGRLFTVTTFGESHGPAIGCVIDGCPPGLEIAPEEFTHDLQRRATGKSRHTSARREADEIEILSGVYEGRTTGTP
IGLLIRNTDQRSKDYTNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQL
GEIRPSGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPPGWGEPIYGKLDSELAAALMSINAV
KGVEIGDGFASAAQKGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGAVVDVITTGRH
DPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPLIPGQADV
>Mature_366_residues
GSNSFGRLFTVTTFGESHGPAIGCVIDGCPPGLEIAPEEFTHDLQRRATGKSRHTSARREADEIEILSGVYEGRTTGTPI
GLLIRNTDQRSKDYTNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLG
EIRPSGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPPGWGEPIYGKLDSELAAALMSINAVK
GVEIGDGFASAAQKGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGAVVDVITTGRHD
PCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPLIPGQADV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=354, Percent_Identity=62.4293785310734, Blast_Score=438, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321290, Length=371, Percent_Identity=40.1617250673854, Blast_Score=264, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39139; Mature: 39007

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSNSFGRLFTVTTFGESHGPAIGCVIDGCPPGLEIAPEEFTHDLQRRATGKSRHTSARR
CCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
EADEIEILSGVYEGRTTGTPIGLLIRNTDQRSKDYTNIAQQFRPGHADYTYWQKYGIRDP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLGEIRPSGFDWDAVEDNPFFW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPPGWGEPIYGKLDSELAAALMSINAV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KGVEIGDGFASAAQKGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRL
CCCCCCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCEEECCCCCCHHEEHEEECCCCCCCC
PGATVDADGAVVDVITTGRHDPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPL
CCCEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IPGQADV
CCCCCCC
>Mature Secondary Structure 
GSNSFGRLFTVTTFGESHGPAIGCVIDGCPPGLEIAPEEFTHDLQRRATGKSRHTSARR
CCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
EADEIEILSGVYEGRTTGTPIGLLIRNTDQRSKDYTNIAQQFRPGHADYTYWQKYGIRDP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLGEIRPSGFDWDAVEDNPFFW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PHAAQVPELETYMDALRKSGDSVGARVDVVAGGVPPGWGEPIYGKLDSELAAALMSINAV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KGVEIGDGFASAAQKGTEHRDLITPEGFLSNHAGGILGGISTGQAVTASMVLKPTSSLRL
CCCCCCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCEEECCCCCCHHEEHEEECCCCCCCC
PGATVDADGAVVDVITTGRHDPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEVSPL
CCCEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IPGQADV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]