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The map label for this gene is rimO [H]

Identifier: 66767878

GI number: 66767878

Start: 1869901

End: 1871274

Strand: Direct

Name: rimO [H]

Synonym: XC_1554

Alternate gene names: 66767878

Gene position: 1869901-1871274 (Clockwise)

Preceding gene: 66767872

Following gene: 77761153

Centisome position: 36.32

GC content: 65.43

Gene sequence:

>1374_bases
ATGTCCCAGCTGAACCCCAAAGTCGGCTTCGTCAGCCTTGGCTGCCCGAAGGCGCTCGTCGATTCCGAACGCATCCTCAC
CCAGCTACGCGTGGAGGGCTACGACATCGTGCCCAGTTACGACGCCGCCGACGTGGTGGTGGTCAATACCTGTGGCTTCA
TCGATTCGGCGGTGACCGAGTCGCTGGATGCGATCGGCGAGGCGATGAACGCCAACGGCAAGGTGATCGTCACCGGCTGC
CTGGGCAAGCGCCCGGAGCAGATCCGCGAGGCCTACCCGCAGGTGCTGGCGGTCTCCGGCCCGCAGGACTACCAGAGCGT
GATGGAGGCGGTGCACGCTGCGCTGCCGCCGCGCCACGATCCGTTCGTGGATCTGGTGCCGGACTACGGCATCAAGCTGA
CGCCGCGCCACTACGCATACCTGAAGATTTCCGAAGGCTGCAATCACCGCTGCAGTTTCTGCATCATTCCTTCCATGCGC
GGCGACCTGGCCTCGCGCCCGGTCGACGAGGTGCTGCGTGAGGCCGAGCGGCTGGTGCGCGGCGGCGTCAAGGAGCTGCT
GGTGGTCTCGCAGGACACCTCGGCCTACGGCGTGGACCTGAAGTATGCCGAGCGCCCGTGGCGCGACCGCATGTACCAGA
CCCGCATGAAGGCGCTGTGCGAAGGCTTGTCGGAACTGGGCGTGTGGACGCGCCTGCATTACGTGTACCCGTACCCGCAC
GTGGACGATGTGATTCCGCTGATGGCCGAAGGCAAGCTGCTGCCGTACCTGGACATCCCGTTCCAGCACGCCAGCCCGCG
CATCCTCAAGCTGATGAAGCGGCCGGGCGCAGTGGAAAAGACCCTGGAGCGCGTGCAGCGCTGGAAGGCGATGTGCCCGG
AGATCACGGTGCGCTCGACCTTCATCGTCGGCTTCCCCGGCGAGACCGATGCCGAGTTCGAAGCGCTGCTGGAGTTTCTG
GATCAGGCGCAGTTGGATCGCGTCGGGGCGTTTGCGTATTCGCCGGTGGAGGGCGCTAGCGCCAACGCATTGCCGGACCC
GGTGCCGGAAGAACTGAAGCAGGAGCGTCTGGCGCGCTTCATGGCCAGGCAGGCGGAGATTTCCGCGGCGCGGCTGGAAG
CCAAGATCGGCAGCGTGCAGCAATGCCTGGTCGACCTGATCGAAGACGATATCGCGGTGGCCCGTTCGCGTGCAGACGCG
CCGGAGATCGACGGCCTGGTGCATATCCAGAACGGCGGCGAGCTCAAGTTGAAGGTGGGCGACCTGGTCGATGTGGAAAT
CACCGACAGCGACGAGCACGACCTGTTCGGTGATGCGCTGCCGTCTGATCCTGCGGCGCAGCCGCCCCGCGCATTGAACC
TGCAGATGGTCTAG

Upstream 100 bases:

>100_bases
TCCACGAAATCGAAAAACGCCGACAGAGCGCTGCCCGGACGCCGCTATAATTGGCCTTGCCCAGGCCCCAGGCCGCTCCG
TTTCCCAGGCTCCTGCTTCC

Downstream 100 bases:

>100_bases
CCGCAGCGGCGTGCCAGCGAGCGGCCAGCGCCGCTGGCCGCTTGGTGTGTGCAATGACACTGGTGTGCGCCGAACTATCC
AGCACATCAGCGTGCAATCG

Product: ribosomal protein S12 methylthiotransferase

Products: NA

Alternate protein names: S12 MTTase; S12 methylthiotransferase; Ribosome maturation factor RimO [H]

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTESLDAIGEAMNANGKVIVTGC
LGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHDPFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMR
GDLASRPVDEVLREAERLVRGGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPH
VDDVIPLMAEGKLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRSTFIVGFPGETDAEFEALLEFL
DQAQLDRVGAFAYSPVEGASANALPDPVPEELKQERLARFMARQAEISAARLEAKIGSVQQCLVDLIEDDIAVARSRADA
PEIDGLVHIQNGGELKLKVGDLVDVEITDSDEHDLFGDALPSDPAAQPPRALNLQMV

Sequences:

>Translated_457_residues
MSQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTESLDAIGEAMNANGKVIVTGC
LGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHDPFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMR
GDLASRPVDEVLREAERLVRGGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPH
VDDVIPLMAEGKLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRSTFIVGFPGETDAEFEALLEFL
DQAQLDRVGAFAYSPVEGASANALPDPVPEELKQERLARFMARQAEISAARLEAKIGSVQQCLVDLIEDDIAVARSRADA
PEIDGLVHIQNGGELKLKVGDLVDVEITDSDEHDLFGDALPSDPAAQPPRALNLQMV
>Mature_456_residues
SQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTESLDAIGEAMNANGKVIVTGCL
GKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHDPFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRG
DLASRPVDEVLREAERLVRGGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPHV
DDVIPLMAEGKLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRSTFIVGFPGETDAEFEALLEFLD
QAQLDRVGAFAYSPVEGASANALPDPVPEELKQERLARFMARQAEISAARLEAKIGSVQQCLVDLIEDDIAVARSRADAP
EIDGLVHIQNGGELKLKVGDLVDVEITDSDEHDLFGDALPSDPAAQPPRALNLQMV

Specific function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 [H]

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=469, Percent_Identity=26.226012793177, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI28872782, Length=478, Percent_Identity=25.5230125523013, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI28872784, Length=478, Percent_Identity=25.5230125523013, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1787057, Length=434, Percent_Identity=66.5898617511521, Blast_Score=616, Evalue=1e-177,
Organism=Escherichia coli, GI1786882, Length=461, Percent_Identity=27.5488069414317, Blast_Score=162, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17553146, Length=461, Percent_Identity=24.9457700650759, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71996771, Length=322, Percent_Identity=23.6024844720497, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356207, Length=483, Percent_Identity=26.0869565217391, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI19922432, Length=374, Percent_Identity=25.4010695187166, Blast_Score=100, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR012340
- InterPro:   IPR007197
- InterPro:   IPR005840
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 50503; Mature: 50372

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTE
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEEECCCHHHHHHHH
SLDAIGEAMNANGKVIVTGCLGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHD
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCC
PFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGDLASRPVDEVLREAERLVR
CCEEECCCCCCEECCCEEEEEEECCCCCCCCCEEEECCCCCCHHCCCHHHHHHHHHHHHH
GGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPH
CCHHHEEEEECCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCC
VDDVIPLMAEGKLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRST
HHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEE
FIVGFPGETDAEFEALLEFLDQAQLDRVGAFAYSPVEGASANALPDPVPEELKQERLARF
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
MARQAEISAARLEAKIGSVQQCLVDLIEDDIAVARSRADAPEIDGLVHIQNGGELKLKVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEC
DLVDVEITDSDEHDLFGDALPSDPAAQPPRALNLQMV
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
>Mature Secondary Structure 
SQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTE
CCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEEECCCHHHHHHHH
SLDAIGEAMNANGKVIVTGCLGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHD
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCC
PFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGDLASRPVDEVLREAERLVR
CCEEECCCCCCEECCCEEEEEEECCCCCCCCCEEEECCCCCCHHCCCHHHHHHHHHHHHH
GGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPH
CCHHHEEEEECCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCC
VDDVIPLMAEGKLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRST
HHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEE
FIVGFPGETDAEFEALLEFLDQAQLDRVGAFAYSPVEGASANALPDPVPEELKQERLARF
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
MARQAEISAARLEAKIGSVQQCLVDLIEDDIAVARSRADAPEIDGLVHIQNGGELKLKVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEC
DLVDVEITDSDEHDLFGDALPSDPAAQPPRALNLQMV
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA