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The map label for this gene is zur [H]

Identifier: 66767756

GI number: 66767756

Start: 1725134

End: 1725652

Strand: Direct

Name: zur [H]

Synonym: XC_1430

Alternate gene names: 66767756

Gene position: 1725134-1725652 (Clockwise)

Preceding gene: 66767755

Following gene: 66767758

Centisome position: 33.51

GC content: 65.51

Gene sequence:

>519_bases
ATGACCAAGCACACGCACACCCAAACGCACGACCAGGAACACGCCTGCACGGCCCCGCACCACCACGTGGACGATGCCAA
CAGCTTCGTACGTGCGGTAGAGCGCGCTTGCAGCGAACGCGGCCTGCGGCTGACGCCGATCCGCGCCAACGTACTGCGGC
TGATCGCCGATGCCGGCAAACCGGTCAAGGCCTACGAGCTGCTGGACTGGGTGCGCGAAGGCAAGGGTGTGGGCGCCGAC
GCCCCGCCAACGGTGTACCGCGCGCTGGATTTTTTGATGGCCAATGGCTTCGTGCACAAGCTCGAATCGGTCAATGCCTT
CGTCGCCTGCCATCACCCCAACAGCGCCCAGCACTCGGTGCCGTTCCTGATCTGCGACCGCTGCCATAGCGCGGTGGAGC
TGGAAGACCGCGATGTGGTCTCGCAACTGGAAGCCCGCGCCAAGGCGCTGGGCTTCCAACCGCAGGCACAGACACTGGAA
GTGCACGGCCTGTGTGCCAAGTGCGCGGCTGCGGGTTGA

Upstream 100 bases:

>100_bases
GACATTTCGCAGACGGTGTACCTGGCCGGGCGCGAGGGTGCCTTGAAACGCATCGATGCGGCACTCATCAAGATTGGAGC
GGCCTGACGCCGGAGCCTGT

Downstream 100 bases:

>100_bases
TTGGTGTGAATCGCGCCGCTGCTCCCGTCTCCTAGCACGCAAGCGGTTCGGGTCAATCGCCCCGCGCAAGACGCTAAACA
ATCGCGATTCACCGTAGGAG

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MTKHTHTQTHDQEHACTAPHHHVDDANSFVRAVERACSERGLRLTPIRANVLRLIADAGKPVKAYELLDWVREGKGVGAD
APPTVYRALDFLMANGFVHKLESVNAFVACHHPNSAQHSVPFLICDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLE
VHGLCAKCAAAG

Sequences:

>Translated_172_residues
MTKHTHTQTHDQEHACTAPHHHVDDANSFVRAVERACSERGLRLTPIRANVLRLIADAGKPVKAYELLDWVREGKGVGAD
APPTVYRALDFLMANGFVHKLESVNAFVACHHPNSAQHSVPFLICDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLE
VHGLCAKCAAAG
>Mature_171_residues
TKHTHTQTHDQEHACTAPHHHVDDANSFVRAVERACSERGLRLTPIRANVLRLIADAGKPVKAYELLDWVREGKGVGADA
PPTVYRALDFLMANGFVHKLESVNAFVACHHPNSAQHSVPFLICDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLEV
HGLCAKCAAAG

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=135, Percent_Identity=43.7037037037037, Blast_Score=117, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18814; Mature: 18683

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKHTHTQTHDQEHACTAPHHHVDDANSFVRAVERACSERGLRLTPIRANVLRLIADAGK
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCC
PVKAYELLDWVREGKGVGADAPPTVYRALDFLMANGFVHKLESVNAFVACHHPNSAQHSV
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
PFLICDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLEVHGLCAKCAAAG
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKHTHTQTHDQEHACTAPHHHVDDANSFVRAVERACSERGLRLTPIRANVLRLIADAGK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCC
PVKAYELLDWVREGKGVGADAPPTVYRALDFLMANGFVHKLESVNAFVACHHPNSAQHSV
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
PFLICDRCHSAVELEDRDVVSQLEARAKALGFQPQAQTLEVHGLCAKCAAAG
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]