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The map label for this gene is ccpA [H]

Identifier: 66767338

GI number: 66767338

Start: 1219554

End: 1220603

Strand: Reverse

Name: ccpA [H]

Synonym: XC_1006

Alternate gene names: 66767338

Gene position: 1220603-1219554 (Counterclockwise)

Preceding gene: 66767339

Following gene: 66767334

Centisome position: 23.71

GC content: 67.33

Gene sequence:

>1050_bases
ATGGCGGCCAAGCGGCAACGCACTGCGACCACGGCAGCAACCCTGCTGGATGTCGCCAAACACGCAGGCGTCTCGCCGAT
GACGGCCTCGCGCGTCATCAACCGCCACCCGCATGTGGGCGAAGACATGCGGGTGCGGGTGGAGGCCTCCGTGCAGGCCT
TGGGCTACCGGCCGAATCTGGCCGGCCGCTCGCTGCGCACCAGTGGATTGCTGCGCATCGGCGTGCTGTACAGCAACCCG
AGTGCGGCGTACCTCAATCAATTCATGCTCGGCCTGCTCGAACAGAGCAGTCTCAATGGCAGCCAGGTGCTGGTGGAGAA
ATGCGGCGCCATCCGCAGCCAGCGCGCTGCCACCGAACGCCTGCTCGCCGCCGGCGTGGATGGCGTGATCCTGCCGCCAC
CGTTGTGCGATTCACGCCAGACCATTGCCGAACTCGATGCACGCGGCATCCCGGTGGTGGCGGTGGCCAGTGGCGCACCG
ATGGCGCAGATCAGCTCGGTGCGCATCGACGACTACCAGGCCGCGCGCGCGCTCGTCGATCATCTGATCGCGCTTGGCCA
TCGCCGCATCGCCTTGATCAAGGGCGACCCCAAACACACACCCAGCGCGCTGCGTGCCAGTGGCTACGCCGACAGCCTGC
AAGCGGCGGGGCTGGAGATCGATGAGGCGCTGATCGCCGAGGGGTTGTTCACCTATCACTCGGGCCTGCTCGCCGCGCGC
GTATTGCTCGCAGAACCCGCACCGCCCACGGCGATCTTCTGCAGCAACGACGACATGGCAGCAGCCACCGTAGCGGTGGC
GCACGGGCTGGGCCTACGCGTGCCCGAGGATGTGTCGGTGGCGGGCTTCGACGACACGCCGGTGGCGACCACCATCTGGC
CCGAACTCACCACCGTGCATCAGCCAGTCACCGCCATGGGCCGCGCAGCGGTCTCACTGCTGGCCGAAGCCATTCGCGAA
CGACGCAAGGGCGCACCAGTGCAAGGCGTGCATCAGGTGATGAAGTACACGCTGGTGAAACGCGGTTCGACGGCGGCGCC
GGTGGTGTGA

Upstream 100 bases:

>100_bases
TGGCGATTTCGGCAGCCGCGCAAAGTCTGTGCAGCCGCCGAACGAGTAAGCTGAGGCGCACTGCCAGCGGTGCGCTTCAA
CTCCAGGACGAGCACACACG

Downstream 100 bases:

>100_bases
TGTGGTGATGGTTGCAAACGTATGGCTGCACGTGCAACGCACAAAAAAAAACCGCATCGCTTCCCGCCGATGCGGCCAAA
TGGGAGGGTGCCCGGGCTTG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MAAKRQRTATTAATLLDVAKHAGVSPMTASRVINRHPHVGEDMRVRVEASVQALGYRPNLAGRSLRTSGLLRIGVLYSNP
SAAYLNQFMLGLLEQSSLNGSQVLVEKCGAIRSQRAATERLLAAGVDGVILPPPLCDSRQTIAELDARGIPVVAVASGAP
MAQISSVRIDDYQAARALVDHLIALGHRRIALIKGDPKHTPSALRASGYADSLQAAGLEIDEALIAEGLFTYHSGLLAAR
VLLAEPAPPTAIFCSNDDMAAATVAVAHGLGLRVPEDVSVAGFDDTPVATTIWPELTTVHQPVTAMGRAAVSLLAEAIRE
RRKGAPVQGVHQVMKYTLVKRGSTAAPVV

Sequences:

>Translated_349_residues
MAAKRQRTATTAATLLDVAKHAGVSPMTASRVINRHPHVGEDMRVRVEASVQALGYRPNLAGRSLRTSGLLRIGVLYSNP
SAAYLNQFMLGLLEQSSLNGSQVLVEKCGAIRSQRAATERLLAAGVDGVILPPPLCDSRQTIAELDARGIPVVAVASGAP
MAQISSVRIDDYQAARALVDHLIALGHRRIALIKGDPKHTPSALRASGYADSLQAAGLEIDEALIAEGLFTYHSGLLAAR
VLLAEPAPPTAIFCSNDDMAAATVAVAHGLGLRVPEDVSVAGFDDTPVATTIWPELTTVHQPVTAMGRAAVSLLAEAIRE
RRKGAPVQGVHQVMKYTLVKRGSTAAPVV
>Mature_348_residues
AAKRQRTATTAATLLDVAKHAGVSPMTASRVINRHPHVGEDMRVRVEASVQALGYRPNLAGRSLRTSGLLRIGVLYSNPS
AAYLNQFMLGLLEQSSLNGSQVLVEKCGAIRSQRAATERLLAAGVDGVILPPPLCDSRQTIAELDARGIPVVAVASGAPM
AQISSVRIDDYQAARALVDHLIALGHRRIALIKGDPKHTPSALRASGYADSLQAAGLEIDEALIAEGLFTYHSGLLAARV
LLAEPAPPTAIFCSNDDMAAATVAVAHGLGLRVPEDVSVAGFDDTPVATTIWPELTTVHQPVTAMGRAAVSLLAEAIRER
RKGAPVQGVHQVMKYTLVKRGSTAAPVV

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=349, Percent_Identity=33.2378223495702, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1787948, Length=345, Percent_Identity=33.0434782608696, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1790194, Length=313, Percent_Identity=33.8658146964856, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789068, Length=296, Percent_Identity=32.7702702702703, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786540, Length=340, Percent_Identity=33.5294117647059, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=29.9093655589124, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1789202, Length=337, Percent_Identity=29.3768545994065, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787580, Length=312, Percent_Identity=25, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788474, Length=302, Percent_Identity=29.1390728476821, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790715, Length=308, Percent_Identity=26.2987012987013, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787906, Length=285, Percent_Identity=28.7719298245614, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789456, Length=319, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36721; Mature: 36590

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKRQRTATTAATLLDVAKHAGVSPMTASRVINRHPHVGEDMRVRVEASVQALGYRPNL
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCCC
AGRSLRTSGLLRIGVLYSNPSAAYLNQFMLGLLEQSSLNGSQVLVEKCGAIRSQRAATER
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LLAAGVDGVILPPPLCDSRQTIAELDARGIPVVAVASGAPMAQISSVRIDDYQAARALVD
HHHHCCCCEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHCEECCHHHHHHHHHH
HLIALGHRRIALIKGDPKHTPSALRASGYADSLQAAGLEIDEALIAEGLFTYHSGLLAAR
HHHHHCCCEEEEEECCCCCCCHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VLLAEPAPPTAIFCSNDDMAAATVAVAHGLGLRVPEDVSVAGFDDTPVATTIWPELTTVH
HHHCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEECCHHHHHH
QPVTAMGRAAVSLLAEAIRERRKGAPVQGVHQVMKYTLVKRGSTAAPVV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AAKRQRTATTAATLLDVAKHAGVSPMTASRVINRHPHVGEDMRVRVEASVQALGYRPNL
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCCC
AGRSLRTSGLLRIGVLYSNPSAAYLNQFMLGLLEQSSLNGSQVLVEKCGAIRSQRAATER
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LLAAGVDGVILPPPLCDSRQTIAELDARGIPVVAVASGAPMAQISSVRIDDYQAARALVD
HHHHCCCCEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHCEECCHHHHHHHHHH
HLIALGHRRIALIKGDPKHTPSALRASGYADSLQAAGLEIDEALIAEGLFTYHSGLLAAR
HHHHHCCCEEEEEECCCCCCCHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VLLAEPAPPTAIFCSNDDMAAATVAVAHGLGLRVPEDVSVAGFDDTPVATTIWPELTTVH
HHHCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEECCHHHHHH
QPVTAMGRAAVSLLAEAIRERRKGAPVQGVHQVMKYTLVKRGSTAAPVV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]