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The map label for this gene is pilQ [H]

Identifier: 66767269

GI number: 66767269

Start: 1124782

End: 1126728

Strand: Reverse

Name: pilQ [H]

Synonym: XC_0937

Alternate gene names: 66767269

Gene position: 1126728-1124782 (Counterclockwise)

Preceding gene: 66767270

Following gene: 66767268

Centisome position: 21.88

GC content: 63.17

Gene sequence:

>1947_bases
ATGACTTTTTCCAACGCCCAGCGCCTGCGTCCGGTCCGGCGCCAGGCAATGCTCCGGGCCTGCGCGCTGGGGTTCGCGCT
GGCGCTGGCGAGCGGCAGTTCGTTTGCCGCCGCCGCGCTGGCCCAGCCTGCGCAGGATCCGGCCAAGACCGCTCCGGCCA
GCCTGGCGGTGTCCAAGATCGACTTCAAGCGCGGCGATGACGGCGCAGGCCGCCTGATCCTGCAGTTCGACGGCCAGGGC
GCCAGCCCCGACCTGCGCACCCAAGGCGACAACGTGCTGGTCGACATCAGCAACGCCCGCCTGCCTGCCGAACTGCAGCG
CCCGCTCAACGTCACCGACTTCGCCACCCCGGTGCAGCGCGTCGAGGTCAAGCCATCCGGTGGCGGCTCGCAGCTGGTGC
TGTCGACCAAGGGTGCATTCGACTCGCTGGCTTACCAGACCGGCAACGAATACGTGGTGGAAATCACCCCGCGCAAGGGC
CAGCCGGCCGTTGGCGGCGTGAGCGTCAGCGCGGTGACGCAGGCGGCCGCGCAGATCGCCGCGCGCGGCTACAGCGGCCG
CCCGGTGACGTTCAACTTCCAGGACGTGCCGGTGCGCACCGTGCTGCAGCTGATCGCCGAGGAATCCAACCTCAACATCG
TGGCTTCCGATACGGTGCAGGGCAATGTCACGCTGCGCCTGATGAACGTGCCGTGGGACCAGGCACTGGACATCGTGCTG
CGCGCCAAAGGCCTGGACAAGCGCCGCGATGGCGGCGTGGTCTGGGTTGCCCCGCAGCCGGAGCTGGCCAAGTTCGAACA
GGACAAGGAAGACGCCCGCATCGCGATTGAAAACCGCGAAGACCTGATCACCGATTACGTGCAGATCAACTACCACAATG
CCGCGGTAATCTTTAAAGCGCTGACCGAGGCCAAGGGCATTGGCGGCGGCGGTGGTGGCGGTGGCCAGGGCGGTCAGGGT
GGTGCCGGGCAGCAGGACAATGGCTTCCTCTCGCCGCGCGGTCGCCTGGTGGCCGACGAGCGCACCAATACCTTGATGAT
CAGCGATATCCCGAAGAAGGTCGCGCAGATGCGCGAGCTGATTTCGCATATCGATCGTCCGGTAGATCAGGTGCTGATCG
AAAGCCGCATCGTGATTGCGACGGATACGTTTGCGCGGGATCTGGGTGCGCGTTTTGGCGTGACCGGAGCGACAGGTCGG
GGTATTTTGAGTGGTTCCCTGGAAAGCAACGTCAACTACCTCAACACCTCGGCACAATCTCGTTTAGAGCAAGCTAACGG
AGGTCAGGTTACAACGCTGCCGGCGCATCTTTTCCCCTCTGGTTTGAACGTTGATCTAGGTGCAGGTGGCTTTACCAATA
GCGGCGCAGCCGGTCTCGCATACACGTTGTTGGGTTCGCACTTCAACCTGGATATTGAGCTGTCGGCGATGCAGGAAGAA
GGCCGAGGCGAGGTTGTGTCCAACCCGCGCATCGTGACCGCCAACCAGCGCGAAGGCGTGATCAAGCAAGGCCGGGAAAT
CGGCTATGTGACCATCAGCGGTGCCGGCGTTGCAGGTGGTGGCTCGCAGGCCAACGTGCAGTTCAAGGAAGTCCTGCTCG
AACTGAAGGTCACGCCCACGATCACCAACGACAACCGCGTCTTCCTCAACATGAATGTCAAGAAGGACGAAGTTGCTCGT
TTCATCACCTTGCCGCAATACGGCACCGTGCCGGAAATCAATCGCCGCGAAGTCAATACGGCGGTCCTGGTGGCTGACGG
CGAGACGGTGGTGATCGGCGGTGTCTACGAATTTACCGATCGTGAGAGCGTGGCGAAGGTGCCGTTCCTTGGCGACATCC
CGTTCCTGGGAAACCTGTTCAAGAAGCGTGGACGCAGCAAGGAAAAGGCCGAGCTGCTGGTCTTCGTCACCCCGAAGGTT
CTGCGGGTTGCGAGCGCCGCGCGGTAA

Upstream 100 bases:

>100_bases
ATCGAGCTGATTGAACTTGTACCGGACGGTGCGGGTGGATGGCTGGAACGGCCTGCCGCGCTCGCATTGGATGATCAATA
AAGTGATAGGGGATAGCACG

Downstream 100 bases:

>100_bases
ACGCGTTGGCAATAGAAGAAGGCCGCGAAAGCGGCCTTTTTCTTTTTAGCGGTCTGTGAAGTGCTCTCAAAACACAACTG
CAAGTGACGTACTTGCTCTG

Product: fimbrial assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MTFSNAQRLRPVRRQAMLRACALGFALALASGSSFAAAALAQPAQDPAKTAPASLAVSKIDFKRGDDGAGRLILQFDGQG
ASPDLRTQGDNVLVDISNARLPAELQRPLNVTDFATPVQRVEVKPSGGGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKG
QPAVGGVSVSAVTQAAAQIAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKALTEAKGIGGGGGGGGQGGQG
GAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELISHIDRPVDQVLIESRIVIATDTFARDLGARFGVTGATGR
GILSGSLESNVNYLNTSAQSRLEQANGGQVTTLPAHLFPSGLNVDLGAGGFTNSGAAGLAYTLLGSHFNLDIELSAMQEE
GRGEVVSNPRIVTANQREGVIKQGREIGYVTISGAGVAGGGSQANVQFKEVLLELKVTPTITNDNRVFLNMNVKKDEVAR
FITLPQYGTVPEINRREVNTAVLVADGETVVIGGVYEFTDRESVAKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKV
LRVASAAR

Sequences:

>Translated_648_residues
MTFSNAQRLRPVRRQAMLRACALGFALALASGSSFAAAALAQPAQDPAKTAPASLAVSKIDFKRGDDGAGRLILQFDGQG
ASPDLRTQGDNVLVDISNARLPAELQRPLNVTDFATPVQRVEVKPSGGGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKG
QPAVGGVSVSAVTQAAAQIAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKALTEAKGIGGGGGGGGQGGQG
GAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELISHIDRPVDQVLIESRIVIATDTFARDLGARFGVTGATGR
GILSGSLESNVNYLNTSAQSRLEQANGGQVTTLPAHLFPSGLNVDLGAGGFTNSGAAGLAYTLLGSHFNLDIELSAMQEE
GRGEVVSNPRIVTANQREGVIKQGREIGYVTISGAGVAGGGSQANVQFKEVLLELKVTPTITNDNRVFLNMNVKKDEVAR
FITLPQYGTVPEINRREVNTAVLVADGETVVIGGVYEFTDRESVAKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKV
LRVASAAR
>Mature_647_residues
TFSNAQRLRPVRRQAMLRACALGFALALASGSSFAAAALAQPAQDPAKTAPASLAVSKIDFKRGDDGAGRLILQFDGQGA
SPDLRTQGDNVLVDISNARLPAELQRPLNVTDFATPVQRVEVKPSGGGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKGQ
PAVGGVSVSAVTQAAAQIAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVLR
AKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKALTEAKGIGGGGGGGGQGGQGG
AGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELISHIDRPVDQVLIESRIVIATDTFARDLGARFGVTGATGRG
ILSGSLESNVNYLNTSAQSRLEQANGGQVTTLPAHLFPSGLNVDLGAGGFTNSGAAGLAYTLLGSHFNLDIELSAMQEEG
RGEVVSNPRIVTANQREGVIKQGREIGYVTISGAGVAGGGSQANVQFKEVLLELKVTPTITNDNRVFLNMNVKKDEVARF
ITLPQYGTVPEINRREVNTAVLVADGETVVIGGVYEFTDRESVAKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKVL
RVASAAR

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=470, Percent_Identity=28.936170212766, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI87082242, Length=308, Percent_Identity=28.8961038961039, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 68894; Mature: 68763

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSNAQRLRPVRRQAMLRACALGFALALASGSSFAAAALAQPAQDPAKTAPASLAVSKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHCCCCCEEEEEE
DFKRGDDGAGRLILQFDGQGASPDLRTQGDNVLVDISNARLPAELQRPLNVTDFATPVQR
ECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHCCCCCE
VEVKPSGGGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKGQPAVGGVSVSAVTQAAAQIA
EEECCCCCCCEEEEEECCCHHHHHEECCCEEEEEEECCCCCCCCCCEEHHHHHHHHHHHH
ARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
HCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEECCEECEEEEEEEECCHHHHHHHHH
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKA
HHCCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEECCHHHEEEEEEEEECCHHHHHHH
LTEAKGIGGGGGGGGQGGQGGAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMREL
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEECCCCCEEEEEHHHHHHHHHHHH
ISHIDRPVDQVLIESRIVIATDTFARDLGARFGVTGATGRGILSGSLESNVNYLNTSAQS
HHHHCCCHHHHHHHCEEEEEECHHHHHHCCCCCCCCCCCCCEEECCHHCCCCEECCHHHH
RLEQANGGQVTTLPAHLFPSGLNVDLGAGGFTNSGAAGLAYTLLGSHFNLDIELSAMQEE
HHHHCCCCEEEEEEHHHCCCCCEEECCCCCCCCCCCCHHEEEECCCCEEEEEEEEEECCC
GRGEVVSNPRIVTANQREGVIKQGREIGYVTISGAGVAGGGSQANVQFKEVLLELKVTPT
CCCCEECCCEEEECCCCCCHHHCCCEEEEEEEECCCCCCCCCCCCEEHHHEEEEEEEEEE
ITNDNRVFLNMNVKKDEVARFITLPQYGTVPEINRREVNTAVLVADGETVVIGGVYEFTD
EECCCEEEEEECCCHHHHHHEEECCCCCCCCCCCCCCCCEEEEEECCCEEEEECEEEECC
RESVAKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKVLRVASAAR
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHCCC
>Mature Secondary Structure 
TFSNAQRLRPVRRQAMLRACALGFALALASGSSFAAAALAQPAQDPAKTAPASLAVSKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHCCCCCEEEEEE
DFKRGDDGAGRLILQFDGQGASPDLRTQGDNVLVDISNARLPAELQRPLNVTDFATPVQR
ECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHCCCCCE
VEVKPSGGGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKGQPAVGGVSVSAVTQAAAQIA
EEECCCCCCCEEEEEECCCHHHHHEECCCEEEEEEECCCCCCCCCCEEHHHHHHHHHHHH
ARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
HCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEECCEECEEEEEEEECCHHHHHHHHH
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKA
HHCCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEECCHHHEEEEEEEEECCHHHHHHH
LTEAKGIGGGGGGGGQGGQGGAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMREL
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEECCCCCEEEEEHHHHHHHHHHHH
ISHIDRPVDQVLIESRIVIATDTFARDLGARFGVTGATGRGILSGSLESNVNYLNTSAQS
HHHHCCCHHHHHHHCEEEEEECHHHHHHCCCCCCCCCCCCCEEECCHHCCCCEECCHHHH
RLEQANGGQVTTLPAHLFPSGLNVDLGAGGFTNSGAAGLAYTLLGSHFNLDIELSAMQEE
HHHHCCCCEEEEEEHHHCCCCCEEECCCCCCCCCCCCHHEEEECCCCEEEEEEEEEECCC
GRGEVVSNPRIVTANQREGVIKQGREIGYVTISGAGVAGGGSQANVQFKEVLLELKVTPT
CCCCEECCCEEEECCCCCCHHHCCCEEEEEEEECCCCCCCCCCCCEEHHHEEEEEEEEEE
ITNDNRVFLNMNVKKDEVARFITLPQYGTVPEINRREVNTAVLVADGETVVIGGVYEFTD
EECCCEEEEEECCCHHHHHHEEECCCCCCCCCCCCCCCCEEEEEECCCEEEEECEEEECC
RESVAKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKVLRVASAAR
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]