Click here to switch to the map view.

The map label for this gene is fhuE [H]

Identifier: 66767256

GI number: 66767256

Start: 1108114

End: 1109634

Strand: Reverse

Name: fhuE [H]

Synonym: XC_0924

Alternate gene names: 66767256

Gene position: 1109634-1108114 (Counterclockwise)

Preceding gene: 66767257

Following gene: 66767254

Centisome position: 21.55

GC content: 62.52

Gene sequence:

>1521_bases
GTGCGCGCACGTGTGATCGGCGTCTACCAGGACGGCGAATCGGACATGGACCGCTACAACCTGCGCAAGAAGATCGGCTC
GGCGATCATTGATGCCGACCTCACCGACAGCACGCTGCTGAGCGTGGGCTACGAGTACCAGAAGAAGGAATCGGACGACG
TCACCTGGGGCGGCTTCCCGCTGTTCTTCAGCGACGGCACGCGCACCAATTACGACCGCTCGTTCAATCCGGCCGCCGAT
TGGACGTTCTGGGATACGCGTCTGCAGCGCACCTTCGCCAGCCTGCAGCAGGGCTTCGACAACGGCTGGACGCTCAAGGC
CAATGTCAGCCATGAGAAGACCGAAGCGGCCAATCATCTGTTCTATCCGTTCTATACGATTTTCGGTTTCGACCGCGCCA
CCGGCGGCGGCGTGGTGCCGTATTCGGGTAACTACCTCACCGAGCGCAAGGCCGACGGCGCCGACGTGTACGCGGAAGGC
CCGTTCCAGCTGTTTGGCCGCGAGCATCACCTGGTCGCCGGCGCCAGTTACAACCGCCGCGAATTCACCAACAACGGCAC
CTTCGATTTCCCGGCGCCGCTGGATACTTACTTCGGCTGGAATGGCGCGTATCCGGAACCCAACTGGAGCCCGCGCACGG
TGCAGAGCACCGGCACGATCAAGCAAAAAGCCGCCTACGTGGCGGGCCGTTTCTCGCTGGCCGACCCGCTGACGCTGCTG
GTGGGCGCGCGCTACACCGACTGGCAGATCGATGGTGGTAACTTCGATGCCGCGCAGGGGCTTGTACCGTTCTCCGACAC
CCAGACCGAAGTCACCCCGTACGCCGGCCTGGTCTACGACATCAACGACGTGTGGTCCACCTACGTCAGCTACACCGAAA
TCTTCAACCCGCAGACCTTGCGCGATGCCAACGGCGGCTACCTGGATCCGTTGACCGGCAAGGGCTACGAAGCCGGCGTC
AAGGCTGCCTGGTTCGACGACAAGCTCAACGCCTCGCTTGCGGTGTTCCGCATCGAACAAGACAACCTGGGCGTGGCCAC
CGGCGGCTTCGTTCCCGGTAGCAGTGAATCGGCGTATGAGGCCGCCAACGGCGTGGTCAGCGAAGGCTTCGACTTCGAGA
TCTCCGGCCGTGTGACCGCCGGTTGGAACACCACCTTTGGTGCCTCGCATTACACCGCGCGCGATGACAGCGGCACGTCG
ATCAATACGCAGCTGCCGCGTACCACCCTCAAGCTGTTCAACAGCTACACCCCGCAAGGTGCGTGGAGCGATCTGACCGT
GGGTGGCGGCGTCAACTGGCAGAACCGTTCGTACTACGTGGACCCGGTGTACGGCGCGTTCCAGCAGAGTGCCTATGCCC
TGGTCAGCGCGTTTGCGCGGTATCGTCTGTCACCGCAGTTCTCGGTGCAGCTCAATATCGACAACCTGCTCGACAAGCGT
TACTACGCGCAGTTCAATGGCGGCTACGGCGCATGGGGCGCATCGCGCAACGGCATGCTGACCTTCAACTACACGTTCTG
A

Upstream 100 bases:

>100_bases
TCAGCCGCGAGTTCACCGGCACCGTGTCGGTGGGTGGCGGCGATTTCAACAAGACCCGCAGCGTGGCCGATGTCACCGTG
CCGCTCAGCCCGGCGGCAAT

Downstream 100 bases:

>100_bases
TCGACGCACACCTGGGGCGTTTTAACGTCTGATGGCTTGGCAATCACACAGGCATCTCGCAGAGATGCCTGTGTTTTTTT
GTGCGCTGATGATCTGTAAC

Product: outer membrane receptor for ferric iron uptake

Products: NA

Alternate protein names: Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MRARVIGVYQDGESDMDRYNLRKKIGSAIIDADLTDSTLLSVGYEYQKKESDDVTWGGFPLFFSDGTRTNYDRSFNPAAD
WTFWDTRLQRTFASLQQGFDNGWTLKANVSHEKTEAANHLFYPFYTIFGFDRATGGGVVPYSGNYLTERKADGADVYAEG
PFQLFGREHHLVAGASYNRREFTNNGTFDFPAPLDTYFGWNGAYPEPNWSPRTVQSTGTIKQKAAYVAGRFSLADPLTLL
VGARYTDWQIDGGNFDAAQGLVPFSDTQTEVTPYAGLVYDINDVWSTYVSYTEIFNPQTLRDANGGYLDPLTGKGYEAGV
KAAWFDDKLNASLAVFRIEQDNLGVATGGFVPGSSESAYEAANGVVSEGFDFEISGRVTAGWNTTFGASHYTARDDSGTS
INTQLPRTTLKLFNSYTPQGAWSDLTVGGGVNWQNRSYYVDPVYGAFQQSAYALVSAFARYRLSPQFSVQLNIDNLLDKR
YYAQFNGGYGAWGASRNGMLTFNYTF

Sequences:

>Translated_506_residues
MRARVIGVYQDGESDMDRYNLRKKIGSAIIDADLTDSTLLSVGYEYQKKESDDVTWGGFPLFFSDGTRTNYDRSFNPAAD
WTFWDTRLQRTFASLQQGFDNGWTLKANVSHEKTEAANHLFYPFYTIFGFDRATGGGVVPYSGNYLTERKADGADVYAEG
PFQLFGREHHLVAGASYNRREFTNNGTFDFPAPLDTYFGWNGAYPEPNWSPRTVQSTGTIKQKAAYVAGRFSLADPLTLL
VGARYTDWQIDGGNFDAAQGLVPFSDTQTEVTPYAGLVYDINDVWSTYVSYTEIFNPQTLRDANGGYLDPLTGKGYEAGV
KAAWFDDKLNASLAVFRIEQDNLGVATGGFVPGSSESAYEAANGVVSEGFDFEISGRVTAGWNTTFGASHYTARDDSGTS
INTQLPRTTLKLFNSYTPQGAWSDLTVGGGVNWQNRSYYVDPVYGAFQQSAYALVSAFARYRLSPQFSVQLNIDNLLDKR
YYAQFNGGYGAWGASRNGMLTFNYTF
>Mature_506_residues
MRARVIGVYQDGESDMDRYNLRKKIGSAIIDADLTDSTLLSVGYEYQKKESDDVTWGGFPLFFSDGTRTNYDRSFNPAAD
WTFWDTRLQRTFASLQQGFDNGWTLKANVSHEKTEAANHLFYPFYTIFGFDRATGGGVVPYSGNYLTERKADGADVYAEG
PFQLFGREHHLVAGASYNRREFTNNGTFDFPAPLDTYFGWNGAYPEPNWSPRTVQSTGTIKQKAAYVAGRFSLADPLTLL
VGARYTDWQIDGGNFDAAQGLVPFSDTQTEVTPYAGLVYDINDVWSTYVSYTEIFNPQTLRDANGGYLDPLTGKGYEAGV
KAAWFDDKLNASLAVFRIEQDNLGVATGGFVPGSSESAYEAANGVVSEGFDFEISGRVTAGWNTTFGASHYTARDDSGTS
INTQLPRTTLKLFNSYTPQGAWSDLTVGGGVNWQNRSYYVDPVYGAFQQSAYALVSAFARYRLSPQFSVQLNIDNLLDKR
YYAQFNGGYGAWGASRNGMLTFNYTF

Specific function: Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid [H]

COG id: COG4773

COG function: function code P; Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=528, Percent_Identity=42.6136363636364, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1786344, Length=360, Percent_Identity=26.1111111111111, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 56163; Mature: 56163

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARVIGVYQDGESDMDRYNLRKKIGSAIIDADLTDSTLLSVGYEYQKKESDDVTWGGFP
CCCEEEEEEECCCCHHHHHHHHHHHCHHEEECCCCCCHHHHCCCHHHCCCCCCCEECCEE
LFFSDGTRTNYDRSFNPAADWTFWDTRLQRTFASLQQGFDNGWTLKANVSHEKTEAANHL
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHCEE
FYPFYTIFGFDRATGGGVVPYSGNYLTERKADGADVYAEGPFQLFGREHHLVAGASYNRR
EEEEHEEEECCCCCCCCCCCCCCCEEECCCCCCCCEEECCCHHHCCCCEEEEECCCCCCC
EFTNNGTFDFPAPLDTYFGWNGAYPEPNWSPRTVQSTGTIKQKAAYVAGRFSLADPLTLL
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHEEECCCCCCCHHHH
VGARYTDWQIDGGNFDAAQGLVPFSDTQTEVTPYAGLVYDINDVWSTYVSYTEIFNPQTL
HCCCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCE
RDANGGYLDPLTGKGYEAGVKAAWFDDKLNASLAVFRIEQDNLGVATGGFVPGSSESAYE
ECCCCCEECCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCCCCCHHH
AANGVVSEGFDFEISGRVTAGWNTTFGASHYTARDDSGTSINTQLPRTTLKLFNSYTPQG
HHCCHHHCCCCEEECCEEEECCCCCCCCCCEECCCCCCCEEECCCCHHHHHHHHCCCCCC
AWSDLTVGGGVNWQNRSYYVDPVYGAFQQSAYALVSAFARYRLSPQFSVQLNIDNLLDKR
CCCCEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHCCC
YYAQFNGGYGAWGASRNGMLTFNYTF
EEEEECCCEEECCCCCCCEEEEEECC
>Mature Secondary Structure
MRARVIGVYQDGESDMDRYNLRKKIGSAIIDADLTDSTLLSVGYEYQKKESDDVTWGGFP
CCCEEEEEEECCCCHHHHHHHHHHHCHHEEECCCCCCHHHHCCCHHHCCCCCCCEECCEE
LFFSDGTRTNYDRSFNPAADWTFWDTRLQRTFASLQQGFDNGWTLKANVSHEKTEAANHL
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHCEE
FYPFYTIFGFDRATGGGVVPYSGNYLTERKADGADVYAEGPFQLFGREHHLVAGASYNRR
EEEEHEEEECCCCCCCCCCCCCCCEEECCCCCCCCEEECCCHHHCCCCEEEEECCCCCCC
EFTNNGTFDFPAPLDTYFGWNGAYPEPNWSPRTVQSTGTIKQKAAYVAGRFSLADPLTLL
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHEEECCCCCCCHHHH
VGARYTDWQIDGGNFDAAQGLVPFSDTQTEVTPYAGLVYDINDVWSTYVSYTEIFNPQTL
HCCCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCE
RDANGGYLDPLTGKGYEAGVKAAWFDDKLNASLAVFRIEQDNLGVATGGFVPGSSESAYE
ECCCCCEECCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCCCCCHHH
AANGVVSEGFDFEISGRVTAGWNTTFGASHYTARDDSGTSINTQLPRTTLKLFNSYTPQG
HHCCHHHCCCCEEECCEEEECCCCCCCCCCEECCCCCCCEEECCCCHHHHHHHHCCCCCC
AWSDLTVGGGVNWQNRSYYVDPVYGAFQQSAYALVSAFARYRLSPQFSVQLNIDNLLDKR
CCCCEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHCCC
YYAQFNGGYGAWGASRNGMLTFNYTF
EEEEECCCEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162465; 8905232; 9278503; 3032906 [H]