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The map label for this gene is rpiA [H]

Identifier: 66767231

GI number: 66767231

Start: 1083201

End: 1083848

Strand: Reverse

Name: rpiA [H]

Synonym: XC_0899

Alternate gene names: 66767231

Gene position: 1083848-1083201 (Counterclockwise)

Preceding gene: 66767232

Following gene: 66767230

Centisome position: 21.05

GC content: 67.13

Gene sequence:

>648_bases
ATGTCCGAAGCAAAACGCCTGGCCGCCGAGAAGGCGATCGATTACGTGGAAGACGGCATGATCGTCGGGGTCGGCACCGG
CTCGACGGTGGCGTATTTCATCGACGCACTCGGCCGCATCGGCCATCGCATCAAGGGTGCGGTGTCCAGCTCGGAACAGA
GCACCGCGCGGCTGCGCCAGCACGGCATCGAGGTGCTGGACCTCAACCACACCGGCACGCTGTCGCTGTATGTGGATGGC
GCCGACGAGTGCGACCCGAACCGCTGCCTGATCAAGGGCGGCGGCGCGGCGCTCACGCGCGAGAAGATCATTGCCGAAGC
GAGCGAGCGCTTCATCTGCATCGTCGACCCGAGCAAGCAGGTGCCGGTGCTGGGCAACTTCCCGCTGCCGGTGGAGGTGA
TCCCGATGGCGCGCAGCCTGGTGGCCCGGCAGATCCTGGCGCTCACGGGCGGGCAGCCGGTCTGGCGTGACGGCGTGGTC
ACCGACAACGGCAACGTGGTGCTGGATGTGCACAACCTGCACATCACCGACCCGGTGGCGCTGGAGCGTAACTTGAATCA
GATTCCCGGCGTGGTCTGCGTGGGTCTGTTCGCGCGCCGCCCGGCCGACGTGGTGATCGTCGGCGGCGAGACACCGCGCG
TGCTGTAA

Upstream 100 bases:

>100_bases
CGGGAGTAGAGATTCGGGATTTGAGATTTGCAAATCCCGGCTCAGCCCAGCCGCTCTTGCGATTCCCCAATCCCGATTCC
CTAATCCCGAGCTCTTACCC

Downstream 100 bases:

>100_bases
GCACGCCCGCATGCGGCCGCAGCCTGGGCACACCACAGGCTGCGGCCACAGCCGTGCGATGGCCGAACCGGCTTGACGCA
CGCTGGCGCTTGGCAGAAGG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQHGIEVLDLNHTGTLSLYVDG
ADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGNFPLPVEVIPMARSLVARQILALTGGQPVWRDGVV
TDNGNVVLDVHNLHITDPVALERNLNQIPGVVCVGLFARRPADVVIVGGETPRVL

Sequences:

>Translated_215_residues
MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQHGIEVLDLNHTGTLSLYVDG
ADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGNFPLPVEVIPMARSLVARQILALTGGQPVWRDGVV
TDNGNVVLDVHNLHITDPVALERNLNQIPGVVCVGLFARRPADVVIVGGETPRVL
>Mature_214_residues
SEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQHGIEVLDLNHTGTLSLYVDGA
DECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGNFPLPVEVIPMARSLVARQILALTGGQPVWRDGVVT
DNGNVVLDVHNLHITDPVALERNLNQIPGVVCVGLFARRPADVVIVGGETPRVL

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=211, Percent_Identity=37.914691943128, Blast_Score=114, Evalue=6e-26,
Organism=Escherichia coli, GI1789280, Length=206, Percent_Identity=62.621359223301, Blast_Score=258, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17551758, Length=208, Percent_Identity=36.5384615384615, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=220, Percent_Identity=33.1818181818182, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281364072, Length=200, Percent_Identity=35.5, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 22920; Mature: 22789

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQ
CCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HGIEVLDLNHTGTLSLYVDGADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQ
CCCEEEEECCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCC
VPVLGNFPLPVEVIPMARSLVARQILALTGGQPVWRDGVVTDNGNVVLDVHNLHITDPVA
CCEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEECEEECCCHH
LERNLNQIPGVVCVGLFARRPADVVIVGGETPRVL
HHCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
SEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQ
CHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HGIEVLDLNHTGTLSLYVDGADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQ
CCCEEEEECCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCC
VPVLGNFPLPVEVIPMARSLVARQILALTGGQPVWRDGVVTDNGNVVLDVHNLHITDPVA
CCEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEECEEECCCHH
LERNLNQIPGVVCVGLFARRPADVVIVGGETPRVL
HHCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]