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The map label for this gene is ppa [H]

Identifier: 66767184

GI number: 66767184

Start: 1030491

End: 1031027

Strand: Reverse

Name: ppa [H]

Synonym: XC_0851

Alternate gene names: 66767184

Gene position: 1031027-1030491 (Counterclockwise)

Preceding gene: 66767186

Following gene: 66767183

Centisome position: 20.02

GC content: 63.5

Gene sequence:

>537_bases
ATGGGCCTGGAACTGGTCACCTCCGGCAAGAACCTGCCGGAAGAAATCAACGTCGTCATCGAGATCCCCAAGGACTCGGA
GCCGGTCAAGTACGAAGTGGACAAGGCCAGCGGCGCGATCTTCGTCGACCGCATCCTGTCGACCCCGATGCGCTACCCCT
GCAACTACGGCTACGTGCCCAACACCCTGTGCGGCGACGGCGACCCGGCCGACGTGCTGGTGGTGCTGCCGCTGCCGCTG
GTGCCCGGTTCGGTGGTGCGTTGCCGCCCGGTCGGCGTGCTGCGCATGAGCGATGAGGCCGGCAGCGACGAGAAGATCCT
GGCAGTGCCGATCGAGAAGATCTTCTCCGGCTACGCCCACATCGAAGATATCGATCAGGTCTCCAGCCACTGGATGGAGC
GCATCGGCCATTTCTTCGAGCATTACAAGGACTTGGAGAAAGGCAAGTGGGTCAAGCTGGACGGCTGGGGCGGCGCGGCG
GAAGCCAAGCGCATCCTGGTGGAGTCGGTGGAACGCTATAATTCCGACGCGCCCTGA

Upstream 100 bases:

>100_bases
CGCTGCTGTCAGACGGAGGCCTATTCAGTGTCGCTGCACCGCAACAGCCGAACGCGTAGAATCGGCCTCCACACACAGCT
GAAGCCTCGGAGCTACGCGC

Downstream 100 bases:

>100_bases
GCCGTCGACCGTGACGCTGCCCCGCACGCGCGGGGCGATCGGCATCACGCTTTTGGCGTGATGCCGGTGACCGCTGTCGG
CAGATTGGGTACATTGCCGA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MGLELVTSGKNLPEEINVVIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVPNTLCGDGDPADVLVVLPLPL
VPGSVVRCRPVGVLRMSDEAGSDEKILAVPIEKIFSGYAHIEDIDQVSSHWMERIGHFFEHYKDLEKGKWVKLDGWGGAA
EAKRILVESVERYNSDAP

Sequences:

>Translated_178_residues
MGLELVTSGKNLPEEINVVIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVPNTLCGDGDPADVLVVLPLPL
VPGSVVRCRPVGVLRMSDEAGSDEKILAVPIEKIFSGYAHIEDIDQVSSHWMERIGHFFEHYKDLEKGKWVKLDGWGGAA
EAKRILVESVERYNSDAP
>Mature_177_residues
GLELVTSGKNLPEEINVVIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVPNTLCGDGDPADVLVVLPLPLV
PGSVVRCRPVGVLRMSDEAGSDEKILAVPIEKIFSGYAHIEDIDQVSSHWMERIGHFFEHYKDLEKGKWVKLDGWGGAAE
AKRILVESVERYNSDAP

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=172, Percent_Identity=60.4651162790698, Blast_Score=219, Evalue=1e-58,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19713; Mature: 19582

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLELVTSGKNLPEEINVVIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVP
CCCEEEECCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCC
NTLCGDGDPADVLVVLPLPLVPGSVVRCRPVGVLRMSDEAGSDEKILAVPIEKIFSGYAH
CCCCCCCCCCCEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCEEEEEHHHHHCCHHH
IEDIDQVSSHWMERIGHFFEHYKDLEKGKWVKLDGWGGAAEAKRILVESVERYNSDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GLELVTSGKNLPEEINVVIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVP
CCEEEECCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCC
NTLCGDGDPADVLVVLPLPLVPGSVVRCRPVGVLRMSDEAGSDEKILAVPIEKIFSGYAH
CCCCCCCCCCCEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCEEEEEHHHHHCCHHH
IEDIDQVSSHWMERIGHFFEHYKDLEKGKWVKLDGWGGAAEAKRILVESVERYNSDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]