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The map label for this gene is rpiA

Identifier: 66048071

GI number: 66048071

Start: 5753950

End: 5754621

Strand: Direct

Name: rpiA

Synonym: Psyr_4847

Alternate gene names: 66048071

Gene position: 5753950-5754621 (Clockwise)

Preceding gene: 66048068

Following gene: 66048076

Centisome position: 94.42

GC content: 61.76

Gene sequence:

>672_bases
ATGACCCAGGATCAACTCAAACAGGCAGTCGCCCAGGCAGCTGTCGACTTCATCCTTCCGAAGCTCGATGACAAAAGCAT
TGTGGGCGTCGGCACCGGCTCCACGGCCAACTGCTTCATCGACGCGCTGGCAAAGCACAAGGCCGCCTTTGACGGTGCTG
TCGCCAGCTCGCAAGCCACTGCGGCGCGCCTGAAGGCGCACGGCATTCCGGTCTATGAGCTGAACACGGTCAGCGATCTG
GAGTTCTATGTCGACGGCGCCGACGAAAGCGACGAGCACCTGAATCTGATCAAGGGCGGCGGCGCGGCACTGACTCGCGA
AAAAATCGTCGCGGCGGTGGCCAATACCTTCATCTGCATCGCCGACGGCAGCAAGCTGGTGCCAGTGCTGGGCGCGTTCC
CGCTGCCGGTCGAAGTCATTCCGATGGCCCGTAGCCACGTGGCGCGGCAACTGGTGAAACTGGGCGGCGACCCGGTTTAT
CGCGAAGGTGTTCTGACCGACAACGGCAACATCATCATTGATGTGCACAACATGAGCATTACCAACCCGGTGGAGCTGGA
AGCGCAGATCAACGCCATCGTCGGCGTGGTCACCAATGGCCTGTTCGCCGCCCGTCCGGCCGACCTGTTGCTGCTGGGTA
CCGCTGAAGGCGTGAAAACCCTGACGCGCTGA

Upstream 100 bases:

>100_bases
GACCATACGAATGACAGGGCTTTGCGGCGCAGTCGCCGCTATAATGCGGGCCTTTTTGCATCCCCCCTCTTCTACCTACA
TCAGGCACCGTGGAGCCCGC

Downstream 100 bases:

>100_bases
TAAAACCGGTCGTGCCCACGCAAGGTGGGCATGACCCTCACAGGCTCAAGGCTTGCGGAACACGTAAAAAAGGTTCGGCT
CGCTCACCAGATACAACGCC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAKHKAAFDGAVASSQATAARLKAHGIPVYELNTVSDL
EFYVDGADESDEHLNLIKGGGAALTREKIVAAVANTFICIADGSKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVY
REGVLTDNGNIIIDVHNMSITNPVELEAQINAIVGVVTNGLFAARPADLLLLGTAEGVKTLTR

Sequences:

>Translated_223_residues
MTQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAKHKAAFDGAVASSQATAARLKAHGIPVYELNTVSDL
EFYVDGADESDEHLNLIKGGGAALTREKIVAAVANTFICIADGSKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVY
REGVLTDNGNIIIDVHNMSITNPVELEAQINAIVGVVTNGLFAARPADLLLLGTAEGVKTLTR
>Mature_222_residues
TQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAKHKAAFDGAVASSQATAARLKAHGIPVYELNTVSDLE
FYVDGADESDEHLNLIKGGGAALTREKIVAAVANTFICIADGSKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVYR
EGVLTDNGNIIIDVHNMSITNPVELEAQINAIVGVVTNGLFAARPADLLLLGTAEGVKTLTR

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=227, Percent_Identity=34.8017621145374, Blast_Score=94, Evalue=8e-20,
Organism=Escherichia coli, GI1789280, Length=223, Percent_Identity=62.780269058296, Blast_Score=275, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17551758, Length=194, Percent_Identity=35.0515463917526, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324669, Length=217, Percent_Identity=35.4838709677419, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281364072, Length=198, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_PSEU2 (Q4ZLU8)

Other databases:

- EMBL:   CP000075
- RefSeq:   YP_237912.1
- HSSP:   P0A7Z0
- ProteinModelPortal:   Q4ZLU8
- SMR:   Q4ZLU8
- STRING:   Q4ZLU8
- GeneID:   3370397
- GenomeReviews:   CP000075_GR
- KEGG:   psb:Psyr_4847
- NMPDR:   fig|205918.4.peg.47
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   DKSIVGV
- ProtClustDB:   PRK00702
- BioCyc:   PSYR205918:PSYR_4847-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23321; Mature: 23190

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAKHKAAFDGAVASSQAT
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
AARLKAHGIPVYELNTVSDLEFYVDGADESDEHLNLIKGGGAALTREKIVAAVANTFICI
HHHHHHCCCCEEEECCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHEEEEE
ADGSKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVYREGVLTDNGNIIIDVHNMSI
ECCCEEEHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECCCC
TNPVELEAQINAIVGVVTNGLFAARPADLLLLGTAEGVKTLTR
CCCEEEHHHHHHHHHHHHCCEEECCCCCEEEEECCHHHHHHCC
>Mature Secondary Structure 
TQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAKHKAAFDGAVASSQAT
CHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
AARLKAHGIPVYELNTVSDLEFYVDGADESDEHLNLIKGGGAALTREKIVAAVANTFICI
HHHHHHCCCCEEEECCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHEEEEE
ADGSKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVYREGVLTDNGNIIIDVHNMSI
ECCCEEEHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECCCC
TNPVELEAQINAIVGVVTNGLFAARPADLLLLGTAEGVKTLTR
CCCEEEHHHHHHHHHHHHCCEEECCCCCEEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA