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The map label for this gene is hutI [H]

Identifier: 66048059

GI number: 66048059

Start: 5739201

End: 5740406

Strand: Direct

Name: hutI [H]

Synonym: Psyr_4835

Alternate gene names: 66048059

Gene position: 5739201-5740406 (Clockwise)

Preceding gene: 66048058

Following gene: 66048060

Centisome position: 94.18

GC content: 63.93

Gene sequence:

>1206_bases
ATGAAAACGCTCTGGAAAAACTGTCACATCGCAAGCATGGCGCACGGCAAATACTCGATCATCGAGGATGCCGCCATCGT
GACCTCCGGAGCGCTCATCGAGTGGATCGGGCCTCAGGCCGCGCTGGCCGAGCCGGAACATGACAACTGCATCGATCTGG
ACGGTGCCTGGGTCACGCCCGGCCTGATCGATTGCCACACCCATACGGTGTTCGGCGGCAACCGCAGCGGCGAGTTCGAA
CAGCGTCTGCAGGGTGTGAGCTACGCCGAGATCGCCGCAGCGGGCGGCGGTATTGCCAGCACGGTGCGTGCCACTCGCGC
CGCCAGTGAGGATGAGCTGTACGCCAGTGCCGAGCGCCGTCTGCGGCATCTGCTGAAAGACGGCGTTACCACCGTCGAGA
TGAAATCGGGTTACGGGCTGGACCTGGAAAACGAGCGCAAGATCCTGCGGGTGATTCGTCGTCTGGGCAACACCCAGCCC
GTCACCGTGCGCGCCACGTGCCTGGCCGCCCACGCGCTGCCACCGGAATACGCCGATCGCGCCGACGATTACATCAACCA
CATCTGCAACGACATGCTCCCGGCGCTGGCAGCCGAAGGACTGGTCGATGCAGTGGATGCCTTCTGTGAATACCTGGCGT
TTTCGCCAGCCCAGGTCGAGCAGGTGTTCATCACCGCAGGGCAGTTGGCACTGCCGGTCAAACTGCATGCCGAGCAGCTG
TCGTCATTGGGCGGATCGAGCCTGGCCGCGCGCTACAAGGCGCTGTCGGCGGATCATCTGGAGTTCATGACCGAAGACGA
CGCCATCGCCATGGCCGCCGCCGGAACCGTCGCGGTGCTGCTGCCGGGGGCGTTTTACTTCCTGCGTGAAACACAACTGC
CGCCGATGGACGCGCTGCGCAAGCACGGCGTGCCGATCGCGATTTCCACCGACCTCAACCCTGGCACGTCGCCGGGTCTG
TCATTGCGCCTGATGCTGAACATGGCCTGCACGCTGTTTCGCATGACGCCCGAAGAAGCACTGGCGGGGGTGACGTTCAA
TGCCGCCAGGGCGCTGGGCATGAGCGCGACCCACGGCTCGCTGGAGGTCGGCAAGGTCGCGGATTTCGTCGCCTGGAACA
TCGAACGACCGGCTGATCTGGCCTATTGGCTGGGCGGCGATCTGGACAAACGCATCGTGCGCCACGGCGTCGAATCATCG
ATCTGA

Upstream 100 bases:

>100_bases
GATCGTCGGCGCAATCTGGATCGTGCTGCTGCTCATTGCCTACGCTGTGTGGGTCAAGCCCAAGGCGCTCAACACCACTC
ATTGATCAACGAGGCCTCGA

Downstream 100 bases:

>100_bases
AGGAGAGCCCTGTGGATAACGTTCTGACATTCAAGCGTGGCCGCATTCCGCTGCTGATCAGCATGCCGCATGCCGGTCTG
AAACTGACCCCGGTGGTCGA

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKTLWKNCHIASMAHGKYSIIEDAAIVTSGALIEWIGPQAALAEPEHDNCIDLDGAWVTPGLIDCHTHTVFGGNRSGEFE
QRLQGVSYAEIAAAGGGIASTVRATRAASEDELYASAERRLRHLLKDGVTTVEMKSGYGLDLENERKILRVIRRLGNTQP
VTVRATCLAAHALPPEYADRADDYINHICNDMLPALAAEGLVDAVDAFCEYLAFSPAQVEQVFITAGQLALPVKLHAEQL
SSLGGSSLAARYKALSADHLEFMTEDDAIAMAAAGTVAVLLPGAFYFLRETQLPPMDALRKHGVPIAISTDLNPGTSPGL
SLRLMLNMACTLFRMTPEEALAGVTFNAARALGMSATHGSLEVGKVADFVAWNIERPADLAYWLGGDLDKRIVRHGVESS
I

Sequences:

>Translated_401_residues
MKTLWKNCHIASMAHGKYSIIEDAAIVTSGALIEWIGPQAALAEPEHDNCIDLDGAWVTPGLIDCHTHTVFGGNRSGEFE
QRLQGVSYAEIAAAGGGIASTVRATRAASEDELYASAERRLRHLLKDGVTTVEMKSGYGLDLENERKILRVIRRLGNTQP
VTVRATCLAAHALPPEYADRADDYINHICNDMLPALAAEGLVDAVDAFCEYLAFSPAQVEQVFITAGQLALPVKLHAEQL
SSLGGSSLAARYKALSADHLEFMTEDDAIAMAAAGTVAVLLPGAFYFLRETQLPPMDALRKHGVPIAISTDLNPGTSPGL
SLRLMLNMACTLFRMTPEEALAGVTFNAARALGMSATHGSLEVGKVADFVAWNIERPADLAYWLGGDLDKRIVRHGVESS
I
>Mature_401_residues
MKTLWKNCHIASMAHGKYSIIEDAAIVTSGALIEWIGPQAALAEPEHDNCIDLDGAWVTPGLIDCHTHTVFGGNRSGEFE
QRLQGVSYAEIAAAGGGIASTVRATRAASEDELYASAERRLRHLLKDGVTTVEMKSGYGLDLENERKILRVIRRLGNTQP
VTVRATCLAAHALPPEYADRADDYINHICNDMLPALAAEGLVDAVDAFCEYLAFSPAQVEQVFITAGQLALPVKLHAEQL
SSLGGSSLAARYKALSADHLEFMTEDDAIAMAAAGTVAVLLPGAFYFLRETQLPPMDALRKHGVPIAISTDLNPGTSPGL
SLRLMLNMACTLFRMTPEEALAGVTFNAARALGMSATHGSLEVGKVADFVAWNIERPADLAYWLGGDLDKRIVRHGVESS
I

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=378, Percent_Identity=38.0952380952381, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17555004, Length=374, Percent_Identity=33.6898395721925, Blast_Score=204, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 43065; Mature: 43065

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLWKNCHIASMAHGKYSIIEDAAIVTSGALIEWIGPQAALAEPEHDNCIDLDGAWVTP
CCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEECCCCHHCCCCCCCCEEECCCCCCCC
GLIDCHTHTVFGGNRSGEFEQRLQGVSYAEIAAAGGGIASTVRATRAASEDELYASAERR
CEEECCCEEEECCCCCCCHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHH
LRHLLKDGVTTVEMKSGYGLDLENERKILRVIRRLGNTQPVTVRATCLAAHALPPEYADR
HHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCHHHHH
ADDYINHICNDMLPALAAEGLVDAVDAFCEYLAFSPAQVEQVFITAGQLALPVKLHAEQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEECCCEEEEHEECHHHH
SSLGGSSLAARYKALSADHLEFMTEDDAIAMAAAGTVAVLLPGAFYFLRETQLPPMDALR
HHCCCHHHHHHHHHHCHHHHHHHCCCCCEEEECCCHHEEHHHHHHEEHHCCCCCCHHHHH
KHGVPIAISTDLNPGTSPGLSLRLMLNMACTLFRMTPEEALAGVTFNAARALGMSATHGS
HCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCCCCCC
LEVGKVADFVAWNIERPADLAYWLGGDLDKRIVRHGVESSI
CCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MKTLWKNCHIASMAHGKYSIIEDAAIVTSGALIEWIGPQAALAEPEHDNCIDLDGAWVTP
CCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEECCCCHHCCCCCCCCEEECCCCCCCC
GLIDCHTHTVFGGNRSGEFEQRLQGVSYAEIAAAGGGIASTVRATRAASEDELYASAERR
CEEECCCEEEECCCCCCCHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHH
LRHLLKDGVTTVEMKSGYGLDLENERKILRVIRRLGNTQPVTVRATCLAAHALPPEYADR
HHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCHHHHH
ADDYINHICNDMLPALAAEGLVDAVDAFCEYLAFSPAQVEQVFITAGQLALPVKLHAEQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEECCCEEEEHEECHHHH
SSLGGSSLAARYKALSADHLEFMTEDDAIAMAAAGTVAVLLPGAFYFLRETQLPPMDALR
HHCCCHHHHHHHHHHCHHHHHHHCCCCCEEEECCCHHEEHHHHHHEEHHCCCCCCHHHHH
KHGVPIAISTDLNPGTSPGLSLRLMLNMACTLFRMTPEEALAGVTFNAARALGMSATHGS
HCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCCCCCC
LEVGKVADFVAWNIERPADLAYWLGGDLDKRIVRHGVESSI
CCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA