Click here to switch to the map view.

The map label for this gene is yafV [C]

Identifier: 66047892

GI number: 66047892

Start: 5532709

End: 5533503

Strand: Direct

Name: yafV [C]

Synonym: Psyr_4668

Alternate gene names: 66047892

Gene position: 5532709-5533503 (Clockwise)

Preceding gene: 66047891

Following gene: 66047893

Centisome position: 90.79

GC content: 63.27

Gene sequence:

>795_bases
ATGCGCGTTGCGCTGTATCAATGCCCACCATTGCCGCTGGATGTCAGCGGCAACCTGACTCGCCTGGAACAGCAGGCTCA
GGCCGCCGCCAAGCAAGGGGCACAGGTGCTGATCTGTCCGGAAATGTTCCTCAGCGGCTACAACATCGGCGCTCAGGCTG
TCGGTGAGCTGGCGCAGGCGCAGGACGGTCCGGCAGCGACGCGCATTGCCGCCATCGCGCAGGCCAGCGGCATTGCGATC
CTCTACGGCTATCCGGAGCGCGCTGGCGATGGGCAGATCTACAACGCCGTGCAGTTGATCGACAGCCAGGGCACGCGCCT
GTGCAACTACCGCAAAACGCACCTGTTCAGCGAGCTGGACAAGTCGATGTTCGTCGCAGGCGACGATCATTACCCGGTGG
TCGAATTGAATGGCTGGCGCCTGGGCCTGCTGATTTGCTACGACGTGGAATTCCCCGAAAATACCCGTCGGCTGGCCCTG
GCCGGGGCCGAATTGATTCTGGTCCCCACCGCGAACATGCTGCCTTACGATTTCGTCTGCGACGTGACCGTCCGGGCGCG
GGCTTTCGAGAATCACTGCTACGTGGTGTACGCCAACTACTGCGGCAGCGAGGGCGCGATTCGTTACTGCGGGCTCAGCA
GCATCTGCGCACCGGACGGCAGCCGCCCGTTGCTGGCAGGTCAGGACGAAGCACTGCTGGTCGGCACGCTGGACAAGTCA
CTGCTGGCCCAGGCCAGAACCGCGAACGACTACTTCGTGGATCGCCGCCCGGCGCTTTATACGTCGCTGACTTGA

Upstream 100 bases:

>100_bases
CCACTTCGGCGGCAAGACTCACGCCGAGAACCCCGGCCCCGGTGATGTGTTCCACGAAATCGGCCCGATAGCACTGGGCG
ACTGACAGAAGGAAAACCCC

Downstream 100 bases:

>100_bases
TCAGATTAGCCGGATGGATAATTCCCACGCAGGAGCGTGCGGAATAATCCTATAACTATCGTGCCCACGCTCCGCGACCA
TCGTCATACACAAGCCCGCT

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MRVALYQCPPLPLDVSGNLTRLEQQAQAAAKQGAQVLICPEMFLSGYNIGAQAVGELAQAQDGPAATRIAAIAQASGIAI
LYGYPERAGDGQIYNAVQLIDSQGTRLCNYRKTHLFSELDKSMFVAGDDHYPVVELNGWRLGLLICYDVEFPENTRRLAL
AGAELILVPTANMLPYDFVCDVTVRARAFENHCYVVYANYCGSEGAIRYCGLSSICAPDGSRPLLAGQDEALLVGTLDKS
LLAQARTANDYFVDRRPALYTSLT

Sequences:

>Translated_264_residues
MRVALYQCPPLPLDVSGNLTRLEQQAQAAAKQGAQVLICPEMFLSGYNIGAQAVGELAQAQDGPAATRIAAIAQASGIAI
LYGYPERAGDGQIYNAVQLIDSQGTRLCNYRKTHLFSELDKSMFVAGDDHYPVVELNGWRLGLLICYDVEFPENTRRLAL
AGAELILVPTANMLPYDFVCDVTVRARAFENHCYVVYANYCGSEGAIRYCGLSSICAPDGSRPLLAGQDEALLVGTLDKS
LLAQARTANDYFVDRRPALYTSLT
>Mature_264_residues
MRVALYQCPPLPLDVSGNLTRLEQQAQAAAKQGAQVLICPEMFLSGYNIGAQAVGELAQAQDGPAATRIAAIAQASGIAI
LYGYPERAGDGQIYNAVQLIDSQGTRLCNYRKTHLFSELDKSMFVAGDDHYPVVELNGWRLGLLICYDVEFPENTRRLAL
AGAELILVPTANMLPYDFVCDVTVRARAFENHCYVVYANYCGSEGAIRYCGLSSICAPDGSRPLLAGQDEALLVGTLDKS
LLAQARTANDYFVDRRPALYTSLT

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=254, Percent_Identity=29.5275590551181, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI5031947, Length=267, Percent_Identity=30.3370786516854, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI297632348, Length=278, Percent_Identity=30.5755395683453, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI297632350, Length=278, Percent_Identity=30.5755395683453, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786412, Length=222, Percent_Identity=29.7297297297297, Blast_Score=81, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17556280, Length=262, Percent_Identity=29.3893129770992, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17533173, Length=269, Percent_Identity=27.1375464684015, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355835, Length=275, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358471, Length=227, Percent_Identity=27.3127753303965, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17933642, Length=259, Percent_Identity=28.957528957529, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28667; Mature: 28667

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVALYQCPPLPLDVSGNLTRLEQQAQAAAKQGAQVLICPEMFLSGYNIGAQAVGELAQA
CEEEEEECCCCCEECCCCHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCHHHHHHHHHC
QDGPAATRIAAIAQASGIAILYGYPERAGDGQIYNAVQLIDSQGTRLCNYRKTHLFSELD
CCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHEEEEEEECCCCCEECCHHHHHHHHHHC
KSMFVAGDDHYPVVELNGWRLGLLICYDVEFPENTRRLALAGAELILVPTANMLPYDFVC
CCEEEECCCCCCEEEECCEEEEEEEEEECCCCCCCCEEEEECCEEEEEECCCCCCEEEEE
DVTVRARAFENHCYVVYANYCGSEGAIRYCGLSSICAPDGSRPLLAGQDEALLVGTLDKS
EEEEEEEEECCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCEECCCCCEEEEEECCHH
LLAQARTANDYFVDRRPALYTSLT
HHHHHCCCCCEEECCCCCEEECCC
>Mature Secondary Structure
MRVALYQCPPLPLDVSGNLTRLEQQAQAAAKQGAQVLICPEMFLSGYNIGAQAVGELAQA
CEEEEEECCCCCEECCCCHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCHHHHHHHHHC
QDGPAATRIAAIAQASGIAILYGYPERAGDGQIYNAVQLIDSQGTRLCNYRKTHLFSELD
CCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHEEEEEEECCCCCEECCHHHHHHHHHHC
KSMFVAGDDHYPVVELNGWRLGLLICYDVEFPENTRRLALAGAELILVPTANMLPYDFVC
CCEEEECCCCCCEEEECCEEEEEEEEEECCCCCCCCEEEEECCEEEEEECCCCCCEEEEE
DVTVRARAFENHCYVVYANYCGSEGAIRYCGLSSICAPDGSRPLLAGQDEALLVGTLDKS
EEEEEEEEECCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCEECCCCCEEEEEECCHH
LLAQARTANDYFVDRRPALYTSLT
HHHHHCCCCCEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8526497 [H]