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The map label for this gene is xerD [H]

Identifier: 66047873

GI number: 66047873

Start: 5509622

End: 5510575

Strand: Direct

Name: xerD [H]

Synonym: Psyr_4646

Alternate gene names: 66047873

Gene position: 5509622-5510575 (Clockwise)

Preceding gene: 66047870

Following gene: 66047877

Centisome position: 90.42

GC content: 59.75

Gene sequence:

>954_bases
GTGACAAAAGTAGTCTCCGACGACCACCGCAGGCTAACGGCGGTCGAATTTCAGCAGCTGGCCAGAGTCCCGTCAGCGGT
CGAGTGGTTTGCCAACTTGGACAACCCGCGCACACGCCGTGCTTATCAAAATGATCTGACGGATTTCTCTTCCTTTATAG
TGCTCGCCAGCGCCGATGATTTTCGCCAGGTCACCCGGTCGCACGTATTGGCCTGGCGCGCCGATCTGGAACAACGCGGC
CTAGCCGGGGCCACCATCCGGCGCAAACTGGCCGCGCTGGCCAGCCTCTTCGATCACCTTCTGGAAAACAATGCCGTCGT
CGGGGGCAACCCGGTGCACGGGGTCAAAAGACCCAGGATAGAAAGCAACGAAGGCAAGACCCCCGCGCTGGGCGATCACC
AGGCCAAGGCCCTGCTCGATGCACCGGATGAAAGCACGCTGAAGGGACTGCGTGATCGGGCCATGCTGGCCGTGCTGCTC
TACCATGGCCTGCGCCGCGAAGAAGCCGCGCAGTTGCAGGTCAGCGACATCCAGGAAAGGCGGGGTATCCAGCACTTGAA
AATCCACGGTAAAGGCGGGAAGGTGCGGTATTTGCCACTGCACCCCGTCGCGGCCGGGCGCATCCATATGTATCTGGAAC
GTTCGGGGCATCATCTGGTAGACAAGAAGGTCCCGCTATTTATATCGCTACGAGGCAAATCGACCGGTGCCGGCGTTTCG
GCCAACGGGATCTATACCGTGGTCGGTGCCTACGCGAAGAAGGCAGGGATTAAGGTTGACGGCTTGGGCGTTCATGGCCT
CAGAGCAACCGCAGCCACCAACGCCCTGGAGCACGAAGCAGACATCGCAAAGGTCCAGGCATGGCTGGGTCATGCCAACA
TCAGCACGACCAAGATCTATGATCGGCGCGAGAACCGGCCGGAGGATTCACCAACCTTCAAAGTGAAATACTGA

Upstream 100 bases:

>100_bases
TCAGGATCGTGTACGCTGCTGGGCATTGGCGTATTTTTTGTGACCGAAATGACGATTCTTGTTCGTCGATGATCCAAAAG
GTGGGTTACACATACAGGAA

Downstream 100 bases:

>100_bases
AACACTGCCTGTGTAATTAGCAGATTTAATTGGCGTGCTTGACCGATACCAGCTTCACGTGCCTGTATTTCTTGCGTGCA
ATCTTCATCGCATCGATTTC

Product: Phage integrase:Phage integrase, N-terminal SAM-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTKVVSDDHRRLTAVEFQQLARVPSAVEWFANLDNPRTRRAYQNDLTDFSSFIVLASADDFRQVTRSHVLAWRADLEQRG
LAGATIRRKLAALASLFDHLLENNAVVGGNPVHGVKRPRIESNEGKTPALGDHQAKALLDAPDESTLKGLRDRAMLAVLL
YHGLRREEAAQLQVSDIQERRGIQHLKIHGKGGKVRYLPLHPVAAGRIHMYLERSGHHLVDKKVPLFISLRGKSTGAGVS
ANGIYTVVGAYAKKAGIKVDGLGVHGLRATAATNALEHEADIAKVQAWLGHANISTTKIYDRRENRPEDSPTFKVKY

Sequences:

>Translated_317_residues
MTKVVSDDHRRLTAVEFQQLARVPSAVEWFANLDNPRTRRAYQNDLTDFSSFIVLASADDFRQVTRSHVLAWRADLEQRG
LAGATIRRKLAALASLFDHLLENNAVVGGNPVHGVKRPRIESNEGKTPALGDHQAKALLDAPDESTLKGLRDRAMLAVLL
YHGLRREEAAQLQVSDIQERRGIQHLKIHGKGGKVRYLPLHPVAAGRIHMYLERSGHHLVDKKVPLFISLRGKSTGAGVS
ANGIYTVVGAYAKKAGIKVDGLGVHGLRATAATNALEHEADIAKVQAWLGHANISTTKIYDRRENRPEDSPTFKVKY
>Mature_316_residues
TKVVSDDHRRLTAVEFQQLARVPSAVEWFANLDNPRTRRAYQNDLTDFSSFIVLASADDFRQVTRSHVLAWRADLEQRGL
AGATIRRKLAALASLFDHLLENNAVVGGNPVHGVKRPRIESNEGKTPALGDHQAKALLDAPDESTLKGLRDRAMLAVLLY
HGLRREEAAQLQVSDIQERRGIQHLKIHGKGGKVRYLPLHPVAAGRIHMYLERSGHHLVDKKVPLFISLRGKSTGAGVSA
NGIYTVVGAYAKKAGIKVDGLGVHGLRATAATNALEHEADIAKVQAWLGHANISTTKIYDRRENRPEDSPTFKVKY

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=30.6122448979592, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790244, Length=266, Percent_Identity=30.8270676691729, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35009; Mature: 34878

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVVSDDHRRLTAVEFQQLARVPSAVEWFANLDNPRTRRAYQNDLTDFSSFIVLASADD
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEECCHH
FRQVTRSHVLAWRADLEQRGLAGATIRRKLAALASLFDHLLENNAVVGGNPVHGVKRPRI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCC
ESNEGKTPALGDHQAKALLDAPDESTLKGLRDRAMLAVLLYHGLRREEAAQLQVSDIQER
CCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RGIQHLKIHGKGGKVRYLPLHPVAAGRIHMYLERSGHHLVDKKVPLFISLRGKSTGAGVS
CCCEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCCEEECCCCCEEEEEECCCCCCCCC
ANGIYTVVGAYAKKAGIKVDGLGVHGLRATAATNALEHEADIAKVQAWLGHANISTTKIY
CCCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DRRENRPEDSPTFKVKY
HHHCCCCCCCCEEEEEC
>Mature Secondary Structure 
TKVVSDDHRRLTAVEFQQLARVPSAVEWFANLDNPRTRRAYQNDLTDFSSFIVLASADD
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEECCHH
FRQVTRSHVLAWRADLEQRGLAGATIRRKLAALASLFDHLLENNAVVGGNPVHGVKRPRI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCC
ESNEGKTPALGDHQAKALLDAPDESTLKGLRDRAMLAVLLYHGLRREEAAQLQVSDIQER
CCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RGIQHLKIHGKGGKVRYLPLHPVAAGRIHMYLERSGHHLVDKKVPLFISLRGKSTGAGVS
CCCEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCCEEECCCCCEEEEEECCCCCCCCC
ANGIYTVVGAYAKKAGIKVDGLGVHGLRATAATNALEHEADIAKVQAWLGHANISTTKIY
CCCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DRRENRPEDSPTFKVKY
HHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]