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The map label for this gene is cobJ [H]

Identifier: 66047641

GI number: 66047641

Start: 5277564

End: 5279267

Strand: Reverse

Name: cobJ [H]

Synonym: Psyr_4414

Alternate gene names: 66047641

Gene position: 5279267-5277564 (Counterclockwise)

Preceding gene: 66047642

Following gene: 66047640

Centisome position: 86.63

GC content: 64.91

Gene sequence:

>1704_bases
ATGACCTCCATGACTCCGGCCATCGTCATTCTCGGCAATGGCAGCCTTGCTACCGCGCGGCGCATTCAACAGCTGTTTCC
CGATGCGCTGATTCATGGCCTGGCCGAGCGCGTGCAGGGGGCCGACCGCACTTACAGCGACTTCGGCGCGACGCTGCGCC
AGTTGTATCAACAGAACACGCCGATCATCGCCCTTTGCGCAGCCGGTATCGTTATCCGCACCCTGGCCGCCGTGCTGCTG
GAGAAGGGCGCCGAACCGCCGGTGCTCGCCGTGGCCGAAGACGGCAGCGCGGTGGTGCCGCTGCTTGGCGGTCTGGGCGG
GGTGAATGTCCTGGCGCGCAGCATCGCCAGCGGGCTTGGCGTTGCGCCGGCGATCACCACCAGCGGCGAGCTGCGTTTCG
GCACCTGCCTGCTCAACCCGCCAAGCGGCTATGCACTGGGCGATCTGGAGCTGGGCAAGCGTTTCGTTTCCGACCTGCTG
TCCGGCGAACCCGTGCGCATCGAGGGTGAAGCCCCCTGGCTGGCTCAGGCGCAACTGCCCGAAGATCCACAGGCGGCGCT
GGCCATTCATGTCGGCAGTGCCCTGCGCGATCCTTCGCCCCATGAATTGCTGATCTACCCACGTAACGTGCTGGTGGCGG
TGACTGAGCTCACCGACGAACTGGCTGAGCACGTGCGCTCGGCCCTGCGTGAGGCTCGTATCGCCGGGCAGTCTCTGGCG
TGCCTGTTGGCTGCCGAGGAGCAGATGGCCAATCCGCACCTGCACAAGGCTGCCGCCGAGCTGGACGTTGCGGTGCGATT
CGTCAGCGCCGCTGCGGCCGGCGAGATGGCCATGAAGGCTGTGCCGCAGCTGTTGCCACCGCTCTGCGTCGATGCCCACA
CCGCGATTGCCGTCGCGGCGCAACCTCTGGAGGTGCAGAGCATCGGCCGCGGGCGTGGCCGCGTTGCAGTCATTGGTCTG
GGTCCTGGCGCAGCAGACCTGATGGTGCCTGCGGTCAAGGCCGAACTGGCACGTGCCAATGATGTGCTGGGCTATGAAAC
CTACGTGCGCATGGCGGGGCCGTTTCGCGCTGATCAGGTACTGCACTGCACTGACAATCGTGAAGAAATGCAGCGTGCCC
GACATGCCTTCGAACTGGCTGCTCAAGGCCGCTCGGTGGTCGTGGTGTCGTCCGGTGATCCAGGGGTTTTCGCCATGGCT
TCAGCGGTGCTTGAAGCGTTGCATGCGTCGGATAATCCTCACTGGCATGCGGTCGAGCTGGAAATTCTGCCCGGTGTCTC
GGCCTCTCTGGCCACCGCCGCCCAGGCCGGTGCGCCGTTGGGGCATGATTTCTGTGTGCTGTCGCTGTCCGACAACCTCA
AGCCCTGGGACATCATCGAAAAGCGTCTGGACCTTGCCTGCCAGGCCGATCTGGCGCTGGCGTTCTACAACCCGATATCC
CGCTCCCGGCCCTGGCAACTGGGGCGTGCGCTGGAGATTGTCCGCCAGCATCGCATCCCTGAAACCCCCGTGACGCTGGG
GCGCGATATCGGCCGTCCCGGGCAGACATTGAGGGTTATCACGCTGGGCGAATTGACCCCGGAACAGGTGGACATGCGCA
CCATGGTGTTGATCGGCTCTTCCCTGACGTGCACCTTTCCTCGCCACGAAGGCGGCAACTGGGTCTATACGCCGCGTTGG
TACGGCAACAAGCCTACAGCGTGA

Upstream 100 bases:

>100_bases
CGATGAGCAACCAGAAAATCGTCCCGCTGGATCAGGTCGACCCGATGTCTTCGCCGTATTTTTCGCTGATTATCGTCCCG
GGCGACAGGTGGCAAGGCTG

Downstream 100 bases:

>100_bases
CCGCGCCCGCGTGTCATACCTGCAGCTCTCTATCGCGGGAAAGTGCTGAAGTGTCGATGTCACTTCAAGCCTGTGGGCCT
GTGTATCGGCTCACAGGCCT

Product: precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MTSMTPAIVILGNGSLATARRIQQLFPDALIHGLAERVQGADRTYSDFGATLRQLYQQNTPIIALCAAGIVIRTLAAVLL
EKGAEPPVLAVAEDGSAVVPLLGGLGGVNVLARSIASGLGVAPAITTSGELRFGTCLLNPPSGYALGDLELGKRFVSDLL
SGEPVRIEGEAPWLAQAQLPEDPQAALAIHVGSALRDPSPHELLIYPRNVLVAVTELTDELAEHVRSALREARIAGQSLA
CLLAAEEQMANPHLHKAAAELDVAVRFVSAAAAGEMAMKAVPQLLPPLCVDAHTAIAVAAQPLEVQSIGRGRGRVAVIGL
GPGAADLMVPAVKAELARANDVLGYETYVRMAGPFRADQVLHCTDNREEMQRARHAFELAAQGRSVVVVSSGDPGVFAMA
SAVLEALHASDNPHWHAVELEILPGVSASLATAAQAGAPLGHDFCVLSLSDNLKPWDIIEKRLDLACQADLALAFYNPIS
RSRPWQLGRALEIVRQHRIPETPVTLGRDIGRPGQTLRVITLGELTPEQVDMRTMVLIGSSLTCTFPRHEGGNWVYTPRW
YGNKPTA

Sequences:

>Translated_567_residues
MTSMTPAIVILGNGSLATARRIQQLFPDALIHGLAERVQGADRTYSDFGATLRQLYQQNTPIIALCAAGIVIRTLAAVLL
EKGAEPPVLAVAEDGSAVVPLLGGLGGVNVLARSIASGLGVAPAITTSGELRFGTCLLNPPSGYALGDLELGKRFVSDLL
SGEPVRIEGEAPWLAQAQLPEDPQAALAIHVGSALRDPSPHELLIYPRNVLVAVTELTDELAEHVRSALREARIAGQSLA
CLLAAEEQMANPHLHKAAAELDVAVRFVSAAAAGEMAMKAVPQLLPPLCVDAHTAIAVAAQPLEVQSIGRGRGRVAVIGL
GPGAADLMVPAVKAELARANDVLGYETYVRMAGPFRADQVLHCTDNREEMQRARHAFELAAQGRSVVVVSSGDPGVFAMA
SAVLEALHASDNPHWHAVELEILPGVSASLATAAQAGAPLGHDFCVLSLSDNLKPWDIIEKRLDLACQADLALAFYNPIS
RSRPWQLGRALEIVRQHRIPETPVTLGRDIGRPGQTLRVITLGELTPEQVDMRTMVLIGSSLTCTFPRHEGGNWVYTPRW
YGNKPTA
>Mature_566_residues
TSMTPAIVILGNGSLATARRIQQLFPDALIHGLAERVQGADRTYSDFGATLRQLYQQNTPIIALCAAGIVIRTLAAVLLE
KGAEPPVLAVAEDGSAVVPLLGGLGGVNVLARSIASGLGVAPAITTSGELRFGTCLLNPPSGYALGDLELGKRFVSDLLS
GEPVRIEGEAPWLAQAQLPEDPQAALAIHVGSALRDPSPHELLIYPRNVLVAVTELTDELAEHVRSALREARIAGQSLAC
LLAAEEQMANPHLHKAAAELDVAVRFVSAAAAGEMAMKAVPQLLPPLCVDAHTAIAVAAQPLEVQSIGRGRGRVAVIGLG
PGAADLMVPAVKAELARANDVLGYETYVRMAGPFRADQVLHCTDNREEMQRARHAFELAAQGRSVVVVSSGDPGVFAMAS
AVLEALHASDNPHWHAVELEILPGVSASLATAAQAGAPLGHDFCVLSLSDNLKPWDIIEKRLDLACQADLALAFYNPISR
SRPWQLGRALEIVRQHRIPETPVTLGRDIGRPGQTLRVITLGELTPEQVDMRTMVLIGSSLTCTFPRHEGGNWVYTPRWY
GNKPTA

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 60153; Mature: 60022

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSMTPAIVILGNGSLATARRIQQLFPDALIHGLAERVQGADRTYSDFGATLRQLYQQNT
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
PIIALCAAGIVIRTLAAVLLEKGAEPPVLAVAEDGSAVVPLLGGLGGVNVLARSIASGLG
CEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEHHHHCCCCHHHHHHHHHHHCCC
VAPAITTSGELRFGTCLLNPPSGYALGDLELGKRFVSDLLSGEPVRIEGEAPWLAQAQLP
CCCEEECCCCEEEEEEEECCCCCCEECHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCC
EDPQAALAIHVGSALRDPSPHELLIYPRNVLVAVTELTDELAEHVRSALREARIAGQSLA
CCCCCEEEEEECHHCCCCCCCEEEEECCHHEEEHHHHHHHHHHHHHHHHHHHHHCCCHHH
CLLAAEEQMANPHLHKAAAELDVAVRFVSAAAAGEMAMKAVPQLLPPLCVDAHTAIAVAA
HHEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHEEEEC
QPLEVQSIGRGRGRVAVIGLGPGAADLMVPAVKAELARANDVLGYETYVRMAGPFRADQV
CCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCCCCE
LHCTDNREEMQRARHAFELAAQGRSVVVVSSGDPGVFAMASAVLEALHASDNPHWHAVEL
EEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
EILPGVSASLATAAQAGAPLGHDFCVLSLSDNLKPWDIIEKRLDLACQADLALAFYNPIS
EEECCCCHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCC
RSRPWQLGRALEIVRQHRIPETPVTLGRDIGRPGQTLRVITLGELTPEQVDMRTMVLIGS
CCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEEECCCCHHHHCCEEEEEECC
SLTCTFPRHEGGNWVYTPRWYGNKPTA
CEEEECCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
TSMTPAIVILGNGSLATARRIQQLFPDALIHGLAERVQGADRTYSDFGATLRQLYQQNT
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
PIIALCAAGIVIRTLAAVLLEKGAEPPVLAVAEDGSAVVPLLGGLGGVNVLARSIASGLG
CEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEHHHHCCCCHHHHHHHHHHHCCC
VAPAITTSGELRFGTCLLNPPSGYALGDLELGKRFVSDLLSGEPVRIEGEAPWLAQAQLP
CCCEEECCCCEEEEEEEECCCCCCEECHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCC
EDPQAALAIHVGSALRDPSPHELLIYPRNVLVAVTELTDELAEHVRSALREARIAGQSLA
CCCCCEEEEEECHHCCCCCCCEEEEECCHHEEEHHHHHHHHHHHHHHHHHHHHHCCCHHH
CLLAAEEQMANPHLHKAAAELDVAVRFVSAAAAGEMAMKAVPQLLPPLCVDAHTAIAVAA
HHEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHEEEEC
QPLEVQSIGRGRGRVAVIGLGPGAADLMVPAVKAELARANDVLGYETYVRMAGPFRADQV
CCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCCCCE
LHCTDNREEMQRARHAFELAAQGRSVVVVSSGDPGVFAMASAVLEALHASDNPHWHAVEL
EEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
EILPGVSASLATAAQAGAPLGHDFCVLSLSDNLKPWDIIEKRLDLACQADLALAFYNPIS
EEECCCCHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCC
RSRPWQLGRALEIVRQHRIPETPVTLGRDIGRPGQTLRVITLGELTPEQVDMRTMVLIGS
CCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEEECCCCHHHHCCEEEEEECC
SLTCTFPRHEGGNWVYTPRWYGNKPTA
CEEEECCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]