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The map label for this gene is dipZ [H]

Identifier: 66047625

GI number: 66047625

Start: 5259326

End: 5261146

Strand: Direct

Name: dipZ [H]

Synonym: Psyr_4398

Alternate gene names: 66047625

Gene position: 5259326-5261146 (Clockwise)

Preceding gene: 66047624

Following gene: 66047626

Centisome position: 86.31

GC content: 62.99

Gene sequence:

>1821_bases
ATGCGCGGACTTTCGATCTTCGAGACTGCCATGCGCCGTTTGTTATGCCTGCTGCTATTGATCCTGGCCCTGCCCGCCTC
CGGCGCCGGTCTGCTGGACAGCCGTCCCTCATCCACCCTGGGCGGTGGCTCGCTGGATAACAGCAAGGACTTCCTGCCTG
TGCGTCAGGCCTTTCAGTTGAGCCTGATCGAGACGACGCCGGAGTCGATCAAACTGAGGCTGGTCGCTACCGACGGCTAC
TACCTGTATCGCCACCGCTTCCAGTTCCGCACCGAGCCTGCCGACATCGGCCTTGGCCAAGCGCAACTGCCCAAGGGCGA
GCAGAAACACGACGAGTACTTTGGCGATGTCGAGGTCTATCACGGCATTCTCGATATCGACCTGCCACGCAAACCCGGCG
AACAGCGCCCCTTTACCCTCGCCGTCACGTACCAGGGCTGCGCCGACAAGGGCTTGTGCTATCCACCTGAAACCGAGCGC
TTGAGCATTGGTGATGTGGCCGCCAGCCCGGCCGAGCAAGCCTCTGCCACCCCACCCGCCGCCACAGCAGCCTGGAGCTG
GAAAGAACTGGCGCTGTTTTTTCTCGCCGGCGTAGGCCTGACCTTTACCCCGTGCGTACTGCCGATGCTGCCGATTCTGT
CCGGCGTGGTACTGCGCGGTCAGGTAGGCGGATTGCGCGGGCTGAGCCTGTCTCTCGCTTACGTACTGCCGATGGCGGCG
TGCTTTGCCCTGCTGGGCGCGCTGATGGGCGTGTTCGGTGCAGGCCTTAACCTGCAGGCGCGCTTGCAATCGGCCTGGGT
ACTGGTGCCGTTCTCGGCATTCTTCGTGATCTTCGCCATTGCCATGTTCGGCGCTTTCGAACTGCGCCTGCCGCAGTCCA
TCAGCTCTCGCCTGGACCGTATCGCCGGCAAGACCCAGGGCGGTTCCTTGTGGGGGGCAGCGGTGCTGGGCGTGGTCTCC
AGCCTGTTGGTGTCACCTTGCGTATCGGCGCCTCTGGCCGGTGCGCTGTTGTACATCAGCGCCAGCGGCGATGCGCTCGG
CGGCGCTCTGAAACTGTTTGCGCTGGGGCTGGGCATGGGCGCGCCGCTGTTGCTGATCGCAACCGGTGGTGCCACATGGC
TGCCGAAAAGCGGCCCTTGGCTGGTGACGGTCAAAAATGCCATCGGTGTGCTGCTGCTGGGACTGGCAATCGGCCTGCTG
AGCCGCGTGCTGCCAGGGCAGGTCACGCTATTGCTGGTGGGTCTGCTGTCGGCCGGTGTCGCGCTGTTTCTCGGTGCGCT
GGAATTCAACATCAAAACCACACGGCAGAAACTCGCCCAACTGTTGGGGCTGGCGCTGCTGGTCTATGCGCTGGCGTGCT
GGTACGGCGCGCTGTCCGGGCAGACCGACCCCATGCGCCCGCTGGGTCGCGAATACGCCCCGGCAAATAACGGGGCAGCA
GCTTCGGTCGCGTCACAGTGGCAGACGATCACCACCTCCGCCGAACTGGACCGTGTGATGCAGGAAGCCCGGCGCGAAAG
CAAACCGCTGGTGCTGGACTGGTATGCCGACTGGTGCATCAGTTGCAAGGTCATCGAACACGAAGTCCTGCCTGACCCGG
GTGTGGTCGCCCGTTTGTCGGGTTACAAACAGGTGCGTTTCGACATGACCGACAGCAACGCAGAGCAACGCGCCCTGCTC
GACCGGTACAAGCTGTTTGGCCCGCCAGCGCTGCTTTTCTTCGATAAAAACGGCGAAGAACGGCAAACTGTGCGGGTTAT
CGGCGAAATCGACGCAGCAGGCCTGATTGAGCGTCTGAACAGCGCCAATGACCAAAACTGA

Upstream 100 bases:

>100_bases
AGCTTTTCCTCGGGCAAGAAATAATTCCGAACCGATTGTGGGCCTGCTGACACCCACTCTTACAACCTGCGCTCGGCAGG
CCGCCGGGCACTCCGTTATC

Downstream 100 bases:

>100_bases
CACCTGAGTCACAAACTTTGCGCGAATATCGCTCATTGTGCTGGCTACTGTTGTTAACTGGACAGTCCATTGCCCTTCCG
GCATAGTCGCCGGGCGTAAA

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase 1; Disulfide reductase 1 [H]

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MRGLSIFETAMRRLLCLLLLILALPASGAGLLDSRPSSTLGGGSLDNSKDFLPVRQAFQLSLIETTPESIKLRLVATDGY
YLYRHRFQFRTEPADIGLGQAQLPKGEQKHDEYFGDVEVYHGILDIDLPRKPGEQRPFTLAVTYQGCADKGLCYPPETER
LSIGDVAASPAEQASATPPAATAAWSWKELALFFLAGVGLTFTPCVLPMLPILSGVVLRGQVGGLRGLSLSLAYVLPMAA
CFALLGALMGVFGAGLNLQARLQSAWVLVPFSAFFVIFAIAMFGAFELRLPQSISSRLDRIAGKTQGGSLWGAAVLGVVS
SLLVSPCVSAPLAGALLYISASGDALGGALKLFALGLGMGAPLLLIATGGATWLPKSGPWLVTVKNAIGVLLLGLAIGLL
SRVLPGQVTLLLVGLLSAGVALFLGALEFNIKTTRQKLAQLLGLALLVYALACWYGALSGQTDPMRPLGREYAPANNGAA
ASVASQWQTITTSAELDRVMQEARRESKPLVLDWYADWCISCKVIEHEVLPDPGVVARLSGYKQVRFDMTDSNAEQRALL
DRYKLFGPPALLFFDKNGEERQTVRVIGEIDAAGLIERLNSANDQN

Sequences:

>Translated_606_residues
MRGLSIFETAMRRLLCLLLLILALPASGAGLLDSRPSSTLGGGSLDNSKDFLPVRQAFQLSLIETTPESIKLRLVATDGY
YLYRHRFQFRTEPADIGLGQAQLPKGEQKHDEYFGDVEVYHGILDIDLPRKPGEQRPFTLAVTYQGCADKGLCYPPETER
LSIGDVAASPAEQASATPPAATAAWSWKELALFFLAGVGLTFTPCVLPMLPILSGVVLRGQVGGLRGLSLSLAYVLPMAA
CFALLGALMGVFGAGLNLQARLQSAWVLVPFSAFFVIFAIAMFGAFELRLPQSISSRLDRIAGKTQGGSLWGAAVLGVVS
SLLVSPCVSAPLAGALLYISASGDALGGALKLFALGLGMGAPLLLIATGGATWLPKSGPWLVTVKNAIGVLLLGLAIGLL
SRVLPGQVTLLLVGLLSAGVALFLGALEFNIKTTRQKLAQLLGLALLVYALACWYGALSGQTDPMRPLGREYAPANNGAA
ASVASQWQTITTSAELDRVMQEARRESKPLVLDWYADWCISCKVIEHEVLPDPGVVARLSGYKQVRFDMTDSNAEQRALL
DRYKLFGPPALLFFDKNGEERQTVRVIGEIDAAGLIERLNSANDQN
>Mature_606_residues
MRGLSIFETAMRRLLCLLLLILALPASGAGLLDSRPSSTLGGGSLDNSKDFLPVRQAFQLSLIETTPESIKLRLVATDGY
YLYRHRFQFRTEPADIGLGQAQLPKGEQKHDEYFGDVEVYHGILDIDLPRKPGEQRPFTLAVTYQGCADKGLCYPPETER
LSIGDVAASPAEQASATPPAATAAWSWKELALFFLAGVGLTFTPCVLPMLPILSGVVLRGQVGGLRGLSLSLAYVLPMAA
CFALLGALMGVFGAGLNLQARLQSAWVLVPFSAFFVIFAIAMFGAFELRLPQSISSRLDRIAGKTQGGSLWGAAVLGVVS
SLLVSPCVSAPLAGALLYISASGDALGGALKLFALGLGMGAPLLLIATGGATWLPKSGPWLVTVKNAIGVLLLGLAIGLL
SRVLPGQVTLLLVGLLSAGVALFLGALEFNIKTTRQKLAQLLGLALLVYALACWYGALSGQTDPMRPLGREYAPANNGAA
ASVASQWQTITTSAELDRVMQEARRESKPLVLDWYADWCISCKVIEHEVLPDPGVVARLSGYKQVRFDMTDSNAEQRALL
DRYKLFGPPALLFFDKNGEERQTVRVIGEIDAAGLIERLNSANDQN

Specific function: Involved in the formation of correct disulfide bonds in some periplasmic proteins and in the assembly of the periplasmic C-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=594, Percent_Identity=36.1952861952862, Blast_Score=318, Evalue=5e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 64686; Mature: 64686

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLSIFETAMRRLLCLLLLILALPASGAGLLDSRPSSTLGGGSLDNSKDFLPVRQAFQL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SLIETTPESIKLRLVATDGYYLYRHRFQFRTEPADIGLGQAQLPKGEQKHDEYFGDVEVY
HHEECCCCCEEEEEEEECCEEEEEEEEHEECCCCCCCCCCCCCCCCCCHHHHHCCCHHHH
HGILDIDLPRKPGEQRPFTLAVTYQGCADKGLCYPPETERLSIGDVAASPAEQASATPPA
CCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCHHHCCCCCCC
ATAAWSWKELALFFLAGVGLTFTPCVLPMLPILSGVVLRGQVGGLRGLSLSLAYVLPMAA
CHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHH
CFALLGALMGVFGAGLNLQARLQSAWVLVPFSAFFVIFAIAMFGAFELRLPQSISSRLDR
HHHHHHHHHHHHCCCCCEEEEHHHCEEEEHHHHHHHHHHHHHHCHHHEECCHHHHHHHHH
IAGKTQGGSLWGAAVLGVVSSLLVSPCVSAPLAGALLYISASGDALGGALKLFALGLGMG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
APLLLIATGGATWLPKSGPWLVTVKNAIGVLLLGLAIGLLSRVLPGQVTLLLVGLLSAGV
CCEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALFLGALEFNIKTTRQKLAQLLGLALLVYALACWYGALSGQTDPMRPLGREYAPANNGAA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
ASVASQWQTITTSAELDRVMQEARRESKPLVLDWYADWCISCKVIEHEVLPDPGVVARLS
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCHHHEEEEEEHHCCCCCCCEEECC
GYKQVRFDMTDSNAEQRALLDRYKLFGPPALLFFDKNGEERQTVRVIGEIDAAGLIERLN
CCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHH
SANDQN
CCCCCC
>Mature Secondary Structure
MRGLSIFETAMRRLLCLLLLILALPASGAGLLDSRPSSTLGGGSLDNSKDFLPVRQAFQL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SLIETTPESIKLRLVATDGYYLYRHRFQFRTEPADIGLGQAQLPKGEQKHDEYFGDVEVY
HHEECCCCCEEEEEEEECCEEEEEEEEHEECCCCCCCCCCCCCCCCCCHHHHHCCCHHHH
HGILDIDLPRKPGEQRPFTLAVTYQGCADKGLCYPPETERLSIGDVAASPAEQASATPPA
CCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCHHHCCCCCCC
ATAAWSWKELALFFLAGVGLTFTPCVLPMLPILSGVVLRGQVGGLRGLSLSLAYVLPMAA
CHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHH
CFALLGALMGVFGAGLNLQARLQSAWVLVPFSAFFVIFAIAMFGAFELRLPQSISSRLDR
HHHHHHHHHHHHCCCCCEEEEHHHCEEEEHHHHHHHHHHHHHHCHHHEECCHHHHHHHHH
IAGKTQGGSLWGAAVLGVVSSLLVSPCVSAPLAGALLYISASGDALGGALKLFALGLGMG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
APLLLIATGGATWLPKSGPWLVTVKNAIGVLLLGLAIGLLSRVLPGQVTLLLVGLLSAGV
CCEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALFLGALEFNIKTTRQKLAQLLGLALLVYALACWYGALSGQTDPMRPLGREYAPANNGAA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
ASVASQWQTITTSAELDRVMQEARRESKPLVLDWYADWCISCKVIEHEVLPDPGVVARLS
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCHHHEEEEEEHHCCCCCCCEEECC
GYKQVRFDMTDSNAEQRALLDRYKLFGPPALLFFDKNGEERQTVRVIGEIDAAGLIERLN
CCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHH
SANDQN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353916; 10984043 [H]