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The map label for this gene is aes [C]

Identifier: 66047610

GI number: 66047610

Start: 5240104

End: 5241006

Strand: Direct

Name: aes [C]

Synonym: Psyr_4383

Alternate gene names: 66047610

Gene position: 5240104-5241006 (Clockwise)

Preceding gene: 66047609

Following gene: 66047612

Centisome position: 85.99

GC content: 62.9

Gene sequence:

>903_bases
ATGATCCGAGTGATTTTCCTGACACTGATGACCGGTGCCGTACTGGCAGCGCTGTCCGGTTGCTCGCCTTTGAAGCTGCT
CAATACGTTGAACCCGAGCGGCCCTGTCGATCATGTCTACAACCTGGCGTACGGGCCGGATCCACGTAATACGCTGGATG
TCTACACGCCCAAGGCCAAACCGGCCAAGGCACCGGTCGTGGTGTTTTTCTACGGCGGCAGCTGGAACAGCGGTTCGAAG
GCTGATTACGCGTTCGTCGGCGAAGCGCTGGCCGCACGAGGCATGGTGGTGATTATCGCCGACTACAGGCTGTATCCACA
GGTACGTTACCCCAGCTTTCTGGAAGACTCGGCCAAGGCGCTGGCCTGGGCGCACAAGCATGCAAACACCTACGGGGGCG
ACCCGAGCCGCCTGTACGTGATGGGCCACAGCGCCGGAGCCTACAACGCCGCAATGCTCGCGCTCGACCCGCGCTGGCTG
GCGCGCGAAGGCTTGTCGCCCTCCATCCTCAGCGGCTGGATCGGGCTGGCAGGGCCTTATGACTTCCTGCCCATCGAGAA
CCCGGACGTGAAGCCAGTGTTCTTCTTCCCCAATTCCCCGCTGGATTCGCAACCCATCAACCACGTCACGTCCAGCGCGC
CACCGGCACTGCTGATGGCCTCGCACACCGACTCGCTGGTCAACCCCAAGCGCAACACCGGCGGCCTGGCCAGGGCGTTG
CGTGAAGCTGGCGTGCCGGTGCGCGACCTGTATTTCTCACGCACCAATCACGGCACGCTGGTCGGCGCATTCGCCAGATT
GCTGAGCGGTCTGGCCCCTGTGGTCGACGAGGTGGACATGTTCGTCAGGCACACGCCGCAAACGGCATCCGAAAAGAACG
CGACCGGGCCAAAGGCTCAGTGA

Upstream 100 bases:

>100_bases
ATCCGCGCAGCAGTGAATGACGTAGCAGCAACTGTGCGGCACTGGGACGAAGCGTGACGGTCTCAGGCATATCCGACTTA
CCTTCCAGAGCCCCTCCGCT

Downstream 100 bases:

>100_bases
ACGAACCAGCCGTCCCTGCGTGTCAGCCGCCAGGCAATGGTCCCCAGGCTCAGGCCGCGCAGCAGGGTAAAAGCCAGGAA
CGTCAGCCATAAGGCGTGGT

Product: esterase/lipase/thioesterase family protein

Products: alcohol; a carboxylate [C]

Alternate protein names: Alpha/Beta Hydrolase Domain-Containing Protein; Lipase; Alpha/Beta Hydrolase Fold-3 Domain Protein; Esterase/Lipase; Esterase/Lipase/Thioesterase Family Protein; Lipase/Esterase; Carboxylesterase Family Protein; Esterase/Lipase-Like Protein; Esterase/Lipase/Thioesterase; Carboxylesterase; Alpha/Beta Hydrolase; N-Acetylanthranilate Amidase; Alpha/Beta Hydrolase Fold-3 Domain-Containing Protein; Aylformamidase; Hydrolase; Arylformamidase; Lipase Active Site; Esterase LipO; Para-Nitrobenzyl Esterase; Alpha/Beta Hydrolase Fold Domain Protein; Membrane-Bound Esterase LipM; Alpha/Beta Hydrolase Fold; Alpha/Beta Hydrolase Fold Family Protein; Carboxylesterase Type B; Dienelactone Hydrolase; Alpha/Beta Hydrolase Family Protein; Conserved Domain Protein; Peptidase; Esterase/Lipase/Thiestherase Protein; Esterase LipC; Alpha/Beta Hydrolase Protein; Esterase LipM; Hydrolase Alpha/Beta Domain Protein

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MIRVIFLTLMTGAVLAALSGCSPLKLLNTLNPSGPVDHVYNLAYGPDPRNTLDVYTPKAKPAKAPVVVFFYGGSWNSGSK
ADYAFVGEALAARGMVVIIADYRLYPQVRYPSFLEDSAKALAWAHKHANTYGGDPSRLYVMGHSAGAYNAAMLALDPRWL
AREGLSPSILSGWIGLAGPYDFLPIENPDVKPVFFFPNSPLDSQPINHVTSSAPPALLMASHTDSLVNPKRNTGGLARAL
REAGVPVRDLYFSRTNHGTLVGAFARLLSGLAPVVDEVDMFVRHTPQTASEKNATGPKAQ

Sequences:

>Translated_300_residues
MIRVIFLTLMTGAVLAALSGCSPLKLLNTLNPSGPVDHVYNLAYGPDPRNTLDVYTPKAKPAKAPVVVFFYGGSWNSGSK
ADYAFVGEALAARGMVVIIADYRLYPQVRYPSFLEDSAKALAWAHKHANTYGGDPSRLYVMGHSAGAYNAAMLALDPRWL
AREGLSPSILSGWIGLAGPYDFLPIENPDVKPVFFFPNSPLDSQPINHVTSSAPPALLMASHTDSLVNPKRNTGGLARAL
REAGVPVRDLYFSRTNHGTLVGAFARLLSGLAPVVDEVDMFVRHTPQTASEKNATGPKAQ
>Mature_300_residues
MIRVIFLTLMTGAVLAALSGCSPLKLLNTLNPSGPVDHVYNLAYGPDPRNTLDVYTPKAKPAKAPVVVFFYGGSWNSGSK
ADYAFVGEALAARGMVVIIADYRLYPQVRYPSFLEDSAKALAWAHKHANTYGGDPSRLYVMGHSAGAYNAAMLALDPRWL
AREGLSPSILSGWIGLAGPYDFLPIENPDVKPVFFFPNSPLDSQPINHVTSSAPPALLMASHTDSLVNPKRNTGGLARAL
REAGVPVRDLYFSRTNHGTLVGAFARLLSGLAPVVDEVDMFVRHTPQTASEKNATGPKAQ

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI224465228, Length=169, Percent_Identity=30.1775147928994, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI192807282, Length=169, Percent_Identity=30.1775147928994, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17557304, Length=155, Percent_Identity=30.9677419354839, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17557282, Length=124, Percent_Identity=33.8709677419355, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17558864, Length=155, Percent_Identity=30.9677419354839, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.- [C]

Molecular weight: Translated: 32233; Mature: 32233

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVIFLTLMTGAVLAALSGCSPLKLLNTLNPSGPVDHVYNLAYGPDPRNTLDVYTPKAK
CEEEEEHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHEECCCCCCCCCCEEEECCCCC
PAKAPVVVFFYGGSWNSGSKADYAFVGEALAARGMVVIIADYRLYPQVRYPSFLEDSAKA
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCEEEEEECCEECCCCCCCHHHHHHHHH
LAWAHKHANTYGGDPSRLYVMGHSAGAYNAAMLALDPRWLAREGLSPSILSGWIGLAGPY
HHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEEECCHHHHHCCCCHHHHHHHHHCCCCC
DFLPIENPDVKPVFFFPNSPLDSQPINHVTSSAPPALLMASHTDSLVNPKRNTGGLARAL
CCCCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCCEEEEECCCCHHCCCCCCCCHHHHHH
REAGVPVRDLYFSRTNHGTLVGAFARLLSGLAPVVDEVDMFVRHTPQTASEKNATGPKAQ
HHCCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIRVIFLTLMTGAVLAALSGCSPLKLLNTLNPSGPVDHVYNLAYGPDPRNTLDVYTPKAK
CEEEEEHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHEECCCCCCCCCCEEEECCCCC
PAKAPVVVFFYGGSWNSGSKADYAFVGEALAARGMVVIIADYRLYPQVRYPSFLEDSAKA
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCEEEEEECCEECCCCCCCHHHHHHHHH
LAWAHKHANTYGGDPSRLYVMGHSAGAYNAAMLALDPRWLAREGLSPSILSGWIGLAGPY
HHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEEECCHHHHHCCCCHHHHHHHHHCCCCC
DFLPIENPDVKPVFFFPNSPLDSQPINHVTSSAPPALLMASHTDSLVNPKRNTGGLARAL
CCCCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCCEEEEECCCCHHCCCCCCCCHHHHHH
REAGVPVRDLYFSRTNHGTLVGAFARLLSGLAPVVDEVDMFVRHTPQTASEKNATGPKAQ
HHCCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA