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The map label for this gene is yhdH [H]

Identifier: 66047429

GI number: 66047429

Start: 4997122

End: 4998558

Strand: Reverse

Name: yhdH [H]

Synonym: Psyr_4202

Alternate gene names: 66047429

Gene position: 4998558-4997122 (Counterclockwise)

Preceding gene: 66047432

Following gene: 66047428

Centisome position: 82.03

GC content: 58.32

Gene sequence:

>1437_bases
ATGCGCGATCTTTTTTGGCTGGGCGTTTCGATAATGTCGACGGACAAGGTTTCGGTCCACGGTAGCTGGGCAAGCCGCTG
GGTGTTCATCCTGGCTGCCACCGGCTCTGCTGTGGGGCTGGGCAGTATCTGGAAATTTCCGTACATGGTCGGTGCCTACG
GCGGCGGTGCATTTGTACTGGTTTTTCTGGCGTGCATCGCGCTGATCGGTATTCCGGTCATGATCGCCGAGACGCTGATT
GGTCGTCGTTCCCGGCTCAGTCCTGCGAATGCGCTCAAGACGCTGGCGCAGGAAGCGGGGCATTCGCCGCGCTGGTCCTG
GGGCGCGTTTGCCGGGATGATCACGGCGCTGCTGATTCTCTCCTTTTATAGTGTGGTGGGCGGCTGGTCGCTGGATTACA
TCATCGACATGGGGCGCGGCGACTTTCAGGGTGTGTCGCCCGATCAGGTCGGTGCGTATTTCGGTGCGGTGATTGCCGAC
CCATGGCGTCTGATTCTGTGGCACACCATTTTCATGCTGCTGTCGGCGGTGGTGATCGGCAAGGGTGTCGAGGCGGGGCT
GGAGAAAAGCCTGCGCATCATGATGCCGATGCTGTTCCTGCTGATGCTGGCGCTGTTGGGCTACAGCCTGACCACGGGGC
ATTTCATGGAAGGCGTGCATTTCATGTTCGACTTCAATCCCGAGAAGGTGCTGGATGGCTTGCTGCCCGCGATGGGCCAT
GCGTTCTTTTCCCTGAGCGTCGGTGTGGGCTCGATCATGGTCTACGGCGCGTACATGACCAAAGGCGCGTCGATCAGCAG
CACGGTTGTCGGCATCGCAATGCTCGATACCTTCGTTTCGCTGTTGGCTGGCCTTGCGCTGTTCCCCATCGTGTTCGCAG
CAGGCCTTAACCCCAGCGAGGGGCCGGGCCTGATGTTCGTCACGTTGCCGTATGCATTCGGCAACGTCGCGTTCGGCCAG
TTGATGGGCATCGTGTTCTTCGTATTGGTGGCCGTTGCAGCCTGGAGTTCGGCAATTTCGTTACTTGAGCCGATGGTCGC
CTATCTGGTCGAGCGCACCCGTATTCGTCGTGCCTGGGTGACGTTCTGGCTGGCCTTTACCTGCTGGTTTGTCGGGCTGG
GCACGGTGTTCTCGTTCAATATCTGGCAAAAAGCCAAGTTTTTCGTGAACGATGGAGGCGCATTCCACCTCTATCATTGG
GGCGCATCGACTGGCCTGGACTTCTTCGGAGTCATTGATTTCTTCACTTCGCGGATCATGTTGCCGCTGGGTGGGTTGTG
TTTTGTAGTATTCGCTGGTTGGGTGATGAGCCGTGAGACGGTGCGCGACGAATTGTCGATTCGCAGTCCGCTGCTCTTCA
ACCTGACGTACTTTTTGATGCGCTACGTGGCGCCGCTCGGCATTCTTGTGGTGTTTGCCGCTCAGCTCTGGAAATGA

Upstream 100 bases:

>100_bases
TGTTTCTTGAGCTTAGCCATAGGGGGCGCATTATAGGCAGTTGCATCAATGTCGGCTACGGGAAAGCGCGTGCTTGAGCA
CAAAGGTTGAATCCCGGACA

Downstream 100 bases:

>100_bases
CGCTCACATGACTACGCATATACAACGCTCTGCTTTACTGCCGTACCCGGCCGGGTTCCTTTATGACCTGGTCAATGATG
TGGCTCGTTATCCCGAGTTT

Product: Sodium:neurotransmitter symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MRDLFWLGVSIMSTDKVSVHGSWASRWVFILAATGSAVGLGSIWKFPYMVGAYGGGAFVLVFLACIALIGIPVMIAETLI
GRRSRLSPANALKTLAQEAGHSPRWSWGAFAGMITALLILSFYSVVGGWSLDYIIDMGRGDFQGVSPDQVGAYFGAVIAD
PWRLILWHTIFMLLSAVVIGKGVEAGLEKSLRIMMPMLFLLMLALLGYSLTTGHFMEGVHFMFDFNPEKVLDGLLPAMGH
AFFSLSVGVGSIMVYGAYMTKGASISSTVVGIAMLDTFVSLLAGLALFPIVFAAGLNPSEGPGLMFVTLPYAFGNVAFGQ
LMGIVFFVLVAVAAWSSAISLLEPMVAYLVERTRIRRAWVTFWLAFTCWFVGLGTVFSFNIWQKAKFFVNDGGAFHLYHW
GASTGLDFFGVIDFFTSRIMLPLGGLCFVVFAGWVMSRETVRDELSIRSPLLFNLTYFLMRYVAPLGILVVFAAQLWK

Sequences:

>Translated_478_residues
MRDLFWLGVSIMSTDKVSVHGSWASRWVFILAATGSAVGLGSIWKFPYMVGAYGGGAFVLVFLACIALIGIPVMIAETLI
GRRSRLSPANALKTLAQEAGHSPRWSWGAFAGMITALLILSFYSVVGGWSLDYIIDMGRGDFQGVSPDQVGAYFGAVIAD
PWRLILWHTIFMLLSAVVIGKGVEAGLEKSLRIMMPMLFLLMLALLGYSLTTGHFMEGVHFMFDFNPEKVLDGLLPAMGH
AFFSLSVGVGSIMVYGAYMTKGASISSTVVGIAMLDTFVSLLAGLALFPIVFAAGLNPSEGPGLMFVTLPYAFGNVAFGQ
LMGIVFFVLVAVAAWSSAISLLEPMVAYLVERTRIRRAWVTFWLAFTCWFVGLGTVFSFNIWQKAKFFVNDGGAFHLYHW
GASTGLDFFGVIDFFTSRIMLPLGGLCFVVFAGWVMSRETVRDELSIRSPLLFNLTYFLMRYVAPLGILVVFAAQLWK
>Mature_478_residues
MRDLFWLGVSIMSTDKVSVHGSWASRWVFILAATGSAVGLGSIWKFPYMVGAYGGGAFVLVFLACIALIGIPVMIAETLI
GRRSRLSPANALKTLAQEAGHSPRWSWGAFAGMITALLILSFYSVVGGWSLDYIIDMGRGDFQGVSPDQVGAYFGAVIAD
PWRLILWHTIFMLLSAVVIGKGVEAGLEKSLRIMMPMLFLLMLALLGYSLTTGHFMEGVHFMFDFNPEKVLDGLLPAMGH
AFFSLSVGVGSIMVYGAYMTKGASISSTVVGIAMLDTFVSLLAGLALFPIVFAAGLNPSEGPGLMFVTLPYAFGNVAFGQ
LMGIVFFVLVAVAAWSSAISLLEPMVAYLVERTRIRRAWVTFWLAFTCWFVGLGTVFSFNIWQKAKFFVNDGGAFHLYHW
GASTGLDFFGVIDFFTSRIMLPLGGLCFVVFAGWVMSRETVRDELSIRSPLLFNLTYFLMRYVAPLGILVVFAAQLWK

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=451, Percent_Identity=23.9467849223947, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI171184408, Length=452, Percent_Identity=22.5663716814159, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI171184406, Length=452, Percent_Identity=22.5663716814159, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI171184404, Length=452, Percent_Identity=22.5663716814159, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI188528618, Length=414, Percent_Identity=21.7391304347826, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI194018524, Length=322, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI33354281, Length=306, Percent_Identity=25.4901960784314, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI58219014, Length=302, Percent_Identity=24.8344370860927, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI51468073, Length=315, Percent_Identity=22.2222222222222, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI11181770, Length=306, Percent_Identity=23.202614379085, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI12408638, Length=280, Percent_Identity=23.5714285714286, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI289191351, Length=408, Percent_Identity=21.078431372549, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4557046, Length=408, Percent_Identity=21.078431372549, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI289191377, Length=408, Percent_Identity=21.078431372549, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI134304856, Length=355, Percent_Identity=23.6619718309859, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI92859670, Length=120, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21361693, Length=112, Percent_Identity=34.8214285714286, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25146584, Length=408, Percent_Identity=19.8529411764706, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554804, Length=384, Percent_Identity=23.1770833333333, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17136952, Length=397, Percent_Identity=21.6624685138539, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19921936, Length=446, Percent_Identity=23.7668161434978, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281364394, Length=397, Percent_Identity=21.6624685138539, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28574704, Length=397, Percent_Identity=21.6624685138539, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17136950, Length=397, Percent_Identity=21.6624685138539, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28574702, Length=397, Percent_Identity=21.6624685138539, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24655079, Length=322, Percent_Identity=23.9130434782609, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639514, Length=420, Percent_Identity=21.6666666666667, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221329674, Length=420, Percent_Identity=21.6666666666667, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582567, Length=433, Percent_Identity=23.5565819861432, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281365034, Length=456, Percent_Identity=21.4912280701754, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639516, Length=303, Percent_Identity=22.4422442244224, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 52263; Mature: 52263

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3 ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLFWLGVSIMSTDKVSVHGSWASRWVFILAATGSAVGLGSIWKFPYMVGAYGGGAFVL
CCCEEEECCEEEECCCEEECCCHHHCEEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHH
VFLACIALIGIPVMIAETLIGRRSRLSPANALKTLAQEAGHSPRWSWGAFAGMITALLIL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
SFYSVVGGWSLDYIIDMGRGDFQGVSPDQVGAYFGAVIADPWRLILWHTIFMLLSAVVIG
HHHHHHCCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KGVEAGLEKSLRIMMPMLFLLMLALLGYSLTTGHFMEGVHFMFDFNPEKVLDGLLPAMGH
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHHH
AFFSLSVGVGSIMVYGAYMTKGASISSTVVGIAMLDTFVSLLAGLALFPIVFAAGLNPSE
HHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GPGLMFVTLPYAFGNVAFGQLMGIVFFVLVAVAAWSSAISLLEPMVAYLVERTRIRRAWV
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFWLAFTCWFVGLGTVFSFNIWQKAKFFVNDGGAFHLYHWGASTGLDFFGVIDFFTSRIM
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHH
LPLGGLCFVVFAGWVMSRETVRDELSIRSPLLFNLTYFLMRYVAPLGILVVFAAQLWK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRDLFWLGVSIMSTDKVSVHGSWASRWVFILAATGSAVGLGSIWKFPYMVGAYGGGAFVL
CCCEEEECCEEEECCCEEECCCHHHCEEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHH
VFLACIALIGIPVMIAETLIGRRSRLSPANALKTLAQEAGHSPRWSWGAFAGMITALLIL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
SFYSVVGGWSLDYIIDMGRGDFQGVSPDQVGAYFGAVIADPWRLILWHTIFMLLSAVVIG
HHHHHHCCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KGVEAGLEKSLRIMMPMLFLLMLALLGYSLTTGHFMEGVHFMFDFNPEKVLDGLLPAMGH
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHHH
AFFSLSVGVGSIMVYGAYMTKGASISSTVVGIAMLDTFVSLLAGLALFPIVFAAGLNPSE
HHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GPGLMFVTLPYAFGNVAFGQLMGIVFFVLVAVAAWSSAISLLEPMVAYLVERTRIRRAWV
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFWLAFTCWFVGLGTVFSFNIWQKAKFFVNDGGAFHLYHWGASTGLDFFGVIDFFTSRIM
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHH
LPLGGLCFVVFAGWVMSRETVRDELSIRSPLLFNLTYFLMRYVAPLGILVVFAAQLWK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]