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The map label for this gene is murA

Identifier: 66047362

GI number: 66047362

Start: 4926055

End: 4927320

Strand: Reverse

Name: murA

Synonym: Psyr_4135

Alternate gene names: 66047362

Gene position: 4927320-4926055 (Counterclockwise)

Preceding gene: 66047363

Following gene: 66047361

Centisome position: 80.86

GC content: 60.9

Gene sequence:

>1266_bases
ATGGATAAACTGATTATTACCGGCGGCGTTCGTCTTGATGGCGAAATTCGCATTTCCGGGGCAAAGAACTCTGCCCTGCC
GATCCTTGCCGCCACGTTGCTGGCGGACGGACCCGTCACCGTTCAGAACCTGCCGCACCTGCACGACATCACGACCATGA
TCGAGCTGTTCGGTCGCATGGGCATCGAGCCTGTGATCGACGAAAAGCTCAGTGTCGAGATCGACCCGCGCACCATCAAG
ACCCTGGTCGCCCCGTACGAGCTGGTGAAAACCATGCGCGCGTCGATTCTGGTGCTGGGCCCGATGGTCGCTCGTTTCGG
CGAGGCTGAAGTCGCTCTGCCGGGTGGCTGTGCCATCGGTTCGCGCCCGGTAGACCTGCACATCCGCGGTCTTGAGGCCA
TGGGCGCGATCATCGACGTCGAAGGTGGCTACATCAAGGCCAAGGCACCTGAGGGTGGCTTGCGCGGTGCCAACTTCTTC
TTCGATACCGTGAGCGTGACCGGTACCGAAAACATCATGATGGCTGCCAGCCTCGCCAACGGTCGCAGCGTGCTGCAGAA
CGCCGCGCGCGAGCCAGAGGTTGTCGATCTGGCCAACTTCCTGATCGCAATGGGTGCCAAGATTCACGGCGCAGGTACCG
ACACCATCACCATCGATGGCGTCAAGCGTCTGGGCCCGGCCACTTACAAGGTCATGCCTGACCGTATCGAGACCGGCACC
TACCTGGTGGCCGCTGCCGTTACCGGCGGTCGCGTCAAGGTCAAGGACACCGATCCGACCATCCTCGAAGCTGTGCTGCT
CAAGCTTCAGGAAGCGGGTGCAGAAGTCACGACCGGTGAAGACTGGATCGAGCTGAACATGCACGGCAAGCGTCCGAAGG
CGGTCAATGTGCGTACCGCGCCTTACCCGGCGTTCCCGACCGACATGCAGGCGCAGTTCATCTCGCTCAACGCGATTGCC
GAAGGCACGGGGGCGGTCATCGAGACCATCTTCGAAAACCGCTTCATGCACGTGTATGAAATGCACCGCATGGGCGCTCA
GATTCAGGTTGAAGGCAATACCGCTATTGTTACCGGCACCGAAGTGCTCAAGGGCGCGCCAGTCATGGCGACCGACCTGC
GTGCATCGGCCAGTCTGGTGATCTCGGCGCTGGTTGCCCAGGGTGACACGCTGATCGACCGCATCTACCACATAGACCGT
GGTTACGAGTGCATCGAAGAGAAGCTGCAAATGCTGGGTGCCAAGATCCGCCGCGTTCCGGGCTAG

Upstream 100 bases:

>100_bases
CCCTGGATTGCCGATGGCAGCATCCACGCGGTGACCATGAAATTTTTCAGCCGCGCTGCATGGGCCGAGCGTTCCTGAGC
CAATTGGTGTCGAGACTCTA

Downstream 100 bases:

>100_bases
CAGCACGCGGCCCTGATGCCGCTGGCATCGGGGCCGCCTGTTCTGTCGCGGGTGTGATTTCTGATTCGTTTCACTTCAGG
TCAACAGGCCTGAGGGTTGT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MDKLIITGGVRLDGEIRISGAKNSALPILAATLLADGPVTVQNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIK
TLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAIIDVEGGYIKAKAPEGGLRGANFF
FDTVSVTGTENIMMAASLANGRSVLQNAAREPEVVDLANFLIAMGAKIHGAGTDTITIDGVKRLGPATYKVMPDRIETGT
YLVAAAVTGGRVKVKDTDPTILEAVLLKLQEAGAEVTTGEDWIELNMHGKRPKAVNVRTAPYPAFPTDMQAQFISLNAIA
EGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGTEVLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDR
GYECIEEKLQMLGAKIRRVPG

Sequences:

>Translated_421_residues
MDKLIITGGVRLDGEIRISGAKNSALPILAATLLADGPVTVQNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIK
TLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAIIDVEGGYIKAKAPEGGLRGANFF
FDTVSVTGTENIMMAASLANGRSVLQNAAREPEVVDLANFLIAMGAKIHGAGTDTITIDGVKRLGPATYKVMPDRIETGT
YLVAAAVTGGRVKVKDTDPTILEAVLLKLQEAGAEVTTGEDWIELNMHGKRPKAVNVRTAPYPAFPTDMQAQFISLNAIA
EGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGTEVLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDR
GYECIEEKLQMLGAKIRRVPG
>Mature_421_residues
MDKLIITGGVRLDGEIRISGAKNSALPILAATLLADGPVTVQNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIK
TLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAIIDVEGGYIKAKAPEGGLRGANFF
FDTVSVTGTENIMMAASLANGRSVLQNAAREPEVVDLANFLIAMGAKIHGAGTDTITIDGVKRLGPATYKVMPDRIETGT
YLVAAAVTGGRVKVKDTDPTILEAVLLKLQEAGAEVTTGEDWIELNMHGKRPKAVNVRTAPYPAFPTDMQAQFISLNAIA
EGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGTEVLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDR
GYECIEEKLQMLGAKIRRVPG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=60.5700712589074, Blast_Score=525, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_PSE14 (Q48EC7)

Other databases:

- EMBL:   CP000058
- RefSeq:   YP_276261.1
- ProteinModelPortal:   Q48EC7
- SMR:   Q48EC7
- STRING:   Q48EC7
- GeneID:   3556370
- GenomeReviews:   CP000058_GR
- KEGG:   psp:PSPPH_4139
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q48EC7
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44971; Mature: 44971

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLIITGGVRLDGEIRISGAKNSALPILAATLLADGPVTVQNLPHLHDITTMIELFGRM
CCCEEEECCEEECCEEEEECCCCCCHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHC
GIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIG
CCCHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHEHHHHHHCCCCEEECCCCCCCC
SRPVDLHIRGLEAMGAIIDVEGGYIKAKAPEGGLRGANFFFDTVSVTGTENIMMAASLAN
CCCEEEEEECHHHCCEEEECCCCEEEEECCCCCCCCCCEEEEEEEECCCCCEEEEEECCC
GRSVLQNAAREPEVVDLANFLIAMGAKIHGAGTDTITIDGVKRLGPATYKVMPDRIETGT
CHHHHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEECCHHHCCCCEEEEECCCCCCCC
YLVAAAVTGGRVKVKDTDPTILEAVLLKLQEAGAEVTTGEDWIELNMHGKRPKAVNVRTA
EEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCEEEEECC
PYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGT
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCCEEEECCCEEEEECH
EVLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVP
HHHCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
G
C
>Mature Secondary Structure
MDKLIITGGVRLDGEIRISGAKNSALPILAATLLADGPVTVQNLPHLHDITTMIELFGRM
CCCEEEECCEEECCEEEEECCCCCCHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHC
GIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIG
CCCHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHEHHHHHHCCCCEEECCCCCCCC
SRPVDLHIRGLEAMGAIIDVEGGYIKAKAPEGGLRGANFFFDTVSVTGTENIMMAASLAN
CCCEEEEEECHHHCCEEEECCCCEEEEECCCCCCCCCCEEEEEEEECCCCCEEEEEECCC
GRSVLQNAAREPEVVDLANFLIAMGAKIHGAGTDTITIDGVKRLGPATYKVMPDRIETGT
CHHHHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEECCHHHCCCCEEEEECCCCCCCC
YLVAAAVTGGRVKVKDTDPTILEAVLLKLQEAGAEVTTGEDWIELNMHGKRPKAVNVRTA
EEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCEEEEECC
PYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGT
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCCEEEECCCEEEEECH
EVLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVP
HHHCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA