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The map label for this gene is sbcB [H]

Identifier: 66047247

GI number: 66047247

Start: 4787147

End: 4788577

Strand: Reverse

Name: sbcB [H]

Synonym: Psyr_4020

Alternate gene names: 66047247

Gene position: 4788577-4787147 (Counterclockwise)

Preceding gene: 66047254

Following gene: 66047245

Centisome position: 78.58

GC content: 57.93

Gene sequence:

>1431_bases
GTGACCTCCAGCATCTTCTGGTACGACTACGAAACCACCGGTATCAACCCGCGCAATGACCGTGCGCTGCAGATGGCCGG
AATTCGCACGGATACCGAGCTCAATGAAATCGCGCCGCCGGTCAATCTGCACTGCCAGCTCAGCGATGACATCCTGCCTC
ATCCTGCCGCCTGCATGATTACCGGAATCACTCCCGCCACGCTGGCAGAAAAAGGCTTGTGCGAGGCCGATTTCATGACG
CGCGTACATGCCGAGCTGTCTGCGCCGGGTACCTGTGGCGCGGGTTACAACACCTTGCGTTTCGATGACGAAGTCACGCG
CTACAGTTTTTATCGCAACTTCTTCGACCCCTATGCACGCGAATGGCAGGGGGGCAACAGTCGCTGGGATCTGATCGATG
TTGTGCGGGCCGCCTATGCATTGCGCCCCGATGGCATTGTCTGGCCGGAGCAGGACGGTCGGGTCACGCTGAAACTGGAG
CGGCTGACGGCTGCCAACGGTATTGATCATGGCCAGGCGCACGATGCGTTATCCGATGTCCGTGCAACGATTGCTCTGGC
ACGTTTGATTCGTGAAAAGCAGCCGAAGCTTTATGACTATCTGTTCGCCTTGCGCAGTAAGCAGAAAGTCCAGGAACAGG
TTCGCCTGATGCAGCCTCTGGTGCATATTTCGGGACGCTTTTCTGCGGCGCGCAATTACCTGGGCGTGGTGCTGCCGTTG
GCCTGGCACCCGCATAATCGCAACGCGCTGATCGTGTGTGATCTGCACCTGGATCATGCACCGTTGTTGCACGAGGACGC
TGAAATACTCAAGCGCCGTTTATATACGCGGCACGATGCGCTGAGCGACGGCGAACTGCCCGTGCCGCTCAAACTGTTGC
ATATAAACCGTTGCCCGGTGATCGCGCCGCTGGGGGTGCTGCGCAGCGAAGATCAGCAGCGGCTGCAACTGGACATGGCC
GGCTATCAGGCACGCGCAACGCAATTGAGTGAAAACCGCGAAGTTTGGCACGGTAAACTGGCTGCCATTTACGGCAAGGA
CGATTTCGCCGCAAGTGAAGATCCCGAACAGCAGTTATATGACGGTTTTATCGGGGACCGTGATCGTCGACTGTGTGAGC
AAGTTCGACAGGCCGAGCCAGAACAACTGGCGCGTGATGCGTGGCCGTTTGATGATGCCCGATTGCCTGAATTGTTATTC
AGGTATCGCGCTCGTAACTTCCCTGACACCTTGAGTGGCGAAGAGCAAACACGCTGGCGGGATTTCTGTCAGCAGCGCTT
GCGCAACCCGGAATGGGGCGCCCCCAACACCCTGCATGACTTTACGGCCGCATGGGTAGAATGCTCCCTTAGTGCCGGGC
CAGAGCAGCTGGAGGTGTTACGGCAGTGGCAGGATTACGCACACAGGCTGAGTAACCGTCTGGGCGTATAA

Upstream 100 bases:

>100_bases
GCTGTAAGAAAACATTTCCCGGTGCGCCGGATACGACCCGATTAGCCAATGACACCTGTCACGCCCTACACTTCGCGGGT
CTTTTGTTCAGGATCAGCCC

Downstream 100 bases:

>100_bases
AAAATACCGGGCAATAAAAAACGCCAGCAGGCTGGCGTTTTTTCAATCGCAATGAACCGCGACCTGGTGAAGCTTAGCCC
AGCAAAGTGGCCCAGCTTTC

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTSSIFWYDYETTGINPRNDRALQMAGIRTDTELNEIAPPVNLHCQLSDDILPHPAACMITGITPATLAEKGLCEADFMT
RVHAELSAPGTCGAGYNTLRFDDEVTRYSFYRNFFDPYAREWQGGNSRWDLIDVVRAAYALRPDGIVWPEQDGRVTLKLE
RLTAANGIDHGQAHDALSDVRATIALARLIREKQPKLYDYLFALRSKQKVQEQVRLMQPLVHISGRFSAARNYLGVVLPL
AWHPHNRNALIVCDLHLDHAPLLHEDAEILKRRLYTRHDALSDGELPVPLKLLHINRCPVIAPLGVLRSEDQQRLQLDMA
GYQARATQLSENREVWHGKLAAIYGKDDFAASEDPEQQLYDGFIGDRDRRLCEQVRQAEPEQLARDAWPFDDARLPELLF
RYRARNFPDTLSGEEQTRWRDFCQQRLRNPEWGAPNTLHDFTAAWVECSLSAGPEQLEVLRQWQDYAHRLSNRLGV

Sequences:

>Translated_476_residues
MTSSIFWYDYETTGINPRNDRALQMAGIRTDTELNEIAPPVNLHCQLSDDILPHPAACMITGITPATLAEKGLCEADFMT
RVHAELSAPGTCGAGYNTLRFDDEVTRYSFYRNFFDPYAREWQGGNSRWDLIDVVRAAYALRPDGIVWPEQDGRVTLKLE
RLTAANGIDHGQAHDALSDVRATIALARLIREKQPKLYDYLFALRSKQKVQEQVRLMQPLVHISGRFSAARNYLGVVLPL
AWHPHNRNALIVCDLHLDHAPLLHEDAEILKRRLYTRHDALSDGELPVPLKLLHINRCPVIAPLGVLRSEDQQRLQLDMA
GYQARATQLSENREVWHGKLAAIYGKDDFAASEDPEQQLYDGFIGDRDRRLCEQVRQAEPEQLARDAWPFDDARLPELLF
RYRARNFPDTLSGEEQTRWRDFCQQRLRNPEWGAPNTLHDFTAAWVECSLSAGPEQLEVLRQWQDYAHRLSNRLGV
>Mature_475_residues
TSSIFWYDYETTGINPRNDRALQMAGIRTDTELNEIAPPVNLHCQLSDDILPHPAACMITGITPATLAEKGLCEADFMTR
VHAELSAPGTCGAGYNTLRFDDEVTRYSFYRNFFDPYAREWQGGNSRWDLIDVVRAAYALRPDGIVWPEQDGRVTLKLER
LTAANGIDHGQAHDALSDVRATIALARLIREKQPKLYDYLFALRSKQKVQEQVRLMQPLVHISGRFSAARNYLGVVLPLA
WHPHNRNALIVCDLHLDHAPLLHEDAEILKRRLYTRHDALSDGELPVPLKLLHINRCPVIAPLGVLRSEDQQRLQLDMAG
YQARATQLSENREVWHGKLAAIYGKDDFAASEDPEQQLYDGFIGDRDRRLCEQVRQAEPEQLARDAWPFDDARLPELLFR
YRARNFPDTLSGEEQTRWRDFCQQRLRNPEWGAPNTLHDFTAAWVECSLSAGPEQLEVLRQWQDYAHRLSNRLGV

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=420, Percent_Identity=49.5238095238095, Blast_Score=401, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54497; Mature: 54366

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSIFWYDYETTGINPRNDRALQMAGIRTDTELNEIAPPVNLHCQLSDDILPHPAACMI
CCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCHHHCCCCCEEEEEECCCCCCCCCCEEE
TGITPATLAEKGLCEADFMTRVHAELSAPGTCGAGYNTLRFDDEVTRYSFYRNFFDPYAR
ECCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHH
EWQGGNSRWDLIDVVRAAYALRPDGIVWPEQDGRVTLKLERLTAANGIDHGQAHDALSDV
HCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEHHCCCCCCCHHHHHHHHH
RATIALARLIREKQPKLYDYLFALRSKQKVQEQVRLMQPLVHISGRFSAARNYLGVVLPL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEEE
AWHPHNRNALIVCDLHLDHAPLLHEDAEILKRRLYTRHDALSDGELPVPLKLLHINRCPV
EECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCC
IAPLGVLRSEDQQRLQLDMAGYQARATQLSENREVWHGKLAAIYGKDDFAASEDPEQQLY
HHCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCCCCCCHHHHHH
DGFIGDRDRRLCEQVRQAEPEQLARDAWPFDDARLPELLFRYRARNFPDTLSGEEQTRWR
HCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
DFCQQRLRNPEWGAPNTLHDFTAAWVECSLSAGPEQLEVLRQWQDYAHRLSNRLGV
HHHHHHCCCCCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSSIFWYDYETTGINPRNDRALQMAGIRTDTELNEIAPPVNLHCQLSDDILPHPAACMI
CCCEEEEEEEECCCCCCCCCEEEEECCCCCCCHHHCCCCCEEEEEECCCCCCCCCCEEE
TGITPATLAEKGLCEADFMTRVHAELSAPGTCGAGYNTLRFDDEVTRYSFYRNFFDPYAR
ECCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHH
EWQGGNSRWDLIDVVRAAYALRPDGIVWPEQDGRVTLKLERLTAANGIDHGQAHDALSDV
HCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEHHCCCCCCCHHHHHHHHH
RATIALARLIREKQPKLYDYLFALRSKQKVQEQVRLMQPLVHISGRFSAARNYLGVVLPL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEEE
AWHPHNRNALIVCDLHLDHAPLLHEDAEILKRRLYTRHDALSDGELPVPLKLLHINRCPV
EECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCC
IAPLGVLRSEDQQRLQLDMAGYQARATQLSENREVWHGKLAAIYGKDDFAASEDPEQQLY
HHCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCCCCCCHHHHHH
DGFIGDRDRRLCEQVRQAEPEQLARDAWPFDDARLPELLFRYRARNFPDTLSGEEQTRWR
HCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
DFCQQRLRNPEWGAPNTLHDFTAAWVECSLSAGPEQLEVLRQWQDYAHRLSNRLGV
HHHHHHCCCCCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]