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The map label for this gene is argF [H]

Identifier: 66047128

GI number: 66047128

Start: 4642209

End: 4643129

Strand: Direct

Name: argF [H]

Synonym: Psyr_3901

Alternate gene names: 66047128

Gene position: 4642209-4643129 (Clockwise)

Preceding gene: 66047124

Following gene: 66047129

Centisome position: 76.18

GC content: 58.85

Gene sequence:

>921_bases
ATGAACGCCAGGCACTTTCTCTCGATGATGGATTACACCCCGGATGAACTCTTGGGCTTGATCCGTCGTGGCGTAGAGCT
TAAAGACCTGCGAAATCGCGGTGTACTTTTTGAACCGCTGAAGAACCGGGTCTTGGGGATGATTTTCGAGAAATCCTCGA
CACGTACCCGTCTTTCTTTTGAAGCAGGGATGATTCAGCTCGGTGGCCAAGCCATCTTTTTGTCGCATCGGGACACCCAG
CTGGGCCGTGGCGAGCCGATTGCCGACAGTGCAAAAGTGATGTCGCGCATGCTGGATGCGGTCATGATCCGTACTTATGC
GCACAGCAATCTGACCGAATTCGCCGCCAATTCACGCGTGCCGGTTATCAACGGCCTGTCCGATGACCTGCACCCGTGCC
AGTTGCTCGCCGACATGCAGACCTTCCTGGAGCATCGCGGCTCGATCAAGGGCAAGACCGTTGCCTGGATCGGCGATGGC
AACAACATGTGCAACAGCTATATAGAAGCGGCGATTCAATTCGACTTCCAGTTGCGTGTGGCCTGCCCTGCCGGCTACGA
GCCAAACGCCGAGTTCCTGGCACTGGCTGGCGAGCGGGTCACCGTGGTCCGCGATCCGAAAGCCGCAGTTGCCGGCGCCC
ATCTGGTCAGCACCGATGTGTGGACCTCCATGGGTCAGGAAGAGGAAACCGCCCGGCGCAAGAAGTTGTTCGCGCCGTTT
CAGGTCACGCGCGCCCTGCTCGACCTAGCCGACAAGGACGTGCTGTTCATGCACTGCCTGCCTGCCCATCGCGGCGAAGA
AATCAGTGTCGACCTGCTGGATGATTCGCGCTCGGTCGCCTGGGATCAGGCAGAAAATCGCCTGCACGCGCAGAAAGCAC
TGCTGGAGTTTCTCGTCGCGCCGTCCTGCAAGCCCGCATGA

Upstream 100 bases:

>100_bases
ATTCGTCGCCCCGTGCGGCTTCCGCCGCAGGTCTAGCCCGTTTTATCGATAAAAACCGGCTTTGATAACCTGCGGTCTGT
TGCAGAAAAGGTAGTTAATC

Downstream 100 bases:

>100_bases
ACCCGTTGCTGCTGAATCTGCGCAACCTCGCTTGCGGCTATCAGAACCAGCGCGTGGTGCAGGATCTGAACCTGCACCTC
AACGCGGGCGATATCGGCTG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase 1; SOCT [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNARHFLSMMDYTPDELLGLIRRGVELKDLRNRGVLFEPLKNRVLGMIFEKSSTRTRLSFEAGMIQLGGQAIFLSHRDTQ
LGRGEPIADSAKVMSRMLDAVMIRTYAHSNLTEFAANSRVPVINGLSDDLHPCQLLADMQTFLEHRGSIKGKTVAWIGDG
NNMCNSYIEAAIQFDFQLRVACPAGYEPNAEFLALAGERVTVVRDPKAAVAGAHLVSTDVWTSMGQEEETARRKKLFAPF
QVTRALLDLADKDVLFMHCLPAHRGEEISVDLLDDSRSVAWDQAENRLHAQKALLEFLVAPSCKPA

Sequences:

>Translated_306_residues
MNARHFLSMMDYTPDELLGLIRRGVELKDLRNRGVLFEPLKNRVLGMIFEKSSTRTRLSFEAGMIQLGGQAIFLSHRDTQ
LGRGEPIADSAKVMSRMLDAVMIRTYAHSNLTEFAANSRVPVINGLSDDLHPCQLLADMQTFLEHRGSIKGKTVAWIGDG
NNMCNSYIEAAIQFDFQLRVACPAGYEPNAEFLALAGERVTVVRDPKAAVAGAHLVSTDVWTSMGQEEETARRKKLFAPF
QVTRALLDLADKDVLFMHCLPAHRGEEISVDLLDDSRSVAWDQAENRLHAQKALLEFLVAPSCKPA
>Mature_306_residues
MNARHFLSMMDYTPDELLGLIRRGVELKDLRNRGVLFEPLKNRVLGMIFEKSSTRTRLSFEAGMIQLGGQAIFLSHRDTQ
LGRGEPIADSAKVMSRMLDAVMIRTYAHSNLTEFAANSRVPVINGLSDDLHPCQLLADMQTFLEHRGSIKGKTVAWIGDG
NNMCNSYIEAAIQFDFQLRVACPAGYEPNAEFLALAGERVTVVRDPKAAVAGAHLVSTDVWTSMGQEEETARRKKLFAPF
QVTRALLDLADKDVLFMHCLPAHRGEEISVDLLDDSRSVAWDQAENRLHAQKALLEFLVAPSCKPA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=295, Percent_Identity=41.0169491525424, Blast_Score=234, Evalue=8e-62,
Organism=Homo sapiens, GI18105007, Length=301, Percent_Identity=30.2325581395349, Blast_Score=109, Evalue=4e-24,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=36, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=36.3076923076923, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI2367364, Length=313, Percent_Identity=29.7124600638978, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994908, Length=316, Percent_Identity=25.6329113924051, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204318, Length=309, Percent_Identity=27.1844660194175, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322373, Length=318, Percent_Identity=32.3899371069182, Blast_Score=183, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6322331, Length=316, Percent_Identity=26.5822784810127, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642586, Length=310, Percent_Identity=28.0645161290323, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 34056; Mature: 34056

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARHFLSMMDYTPDELLGLIRRGVELKDLRNRGVLFEPLKNRVLGMIFEKSSTRTRLSF
CCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHEEECCCCCEEEEE
EAGMIQLGGQAIFLSHRDTQLGRGEPIADSAKVMSRMLDAVMIRTYAHSNLTEFAANSRV
ECCEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
PVINGLSDDLHPCQLLADMQTFLEHRGSIKGKTVAWIGDGNNMCNSYIEAAIQFDFQLRV
CEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHEEEEEEEE
ACPAGYEPNAEFLALAGERVTVVRDPKAAVAGAHLVSTDVWTSMGQEEETARRKKLFAPF
ECCCCCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHH
QVTRALLDLADKDVLFMHCLPAHRGEEISVDLLDDSRSVAWDQAENRLHAQKALLEFLVA
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
PSCKPA
CCCCCC
>Mature Secondary Structure
MNARHFLSMMDYTPDELLGLIRRGVELKDLRNRGVLFEPLKNRVLGMIFEKSSTRTRLSF
CCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHEEECCCCCEEEEE
EAGMIQLGGQAIFLSHRDTQLGRGEPIADSAKVMSRMLDAVMIRTYAHSNLTEFAANSRV
ECCEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
PVINGLSDDLHPCQLLADMQTFLEHRGSIKGKTVAWIGDGNNMCNSYIEAAIQFDFQLRV
CEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHEEEEEEEE
ACPAGYEPNAEFLALAGERVTVVRDPKAAVAGAHLVSTDVWTSMGQEEETARRKKLFAPF
ECCCCCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHH
QVTRALLDLADKDVLFMHCLPAHRGEEISVDLLDDSRSVAWDQAENRLHAQKALLEFLVA
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
PSCKPA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1522066 [H]