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The map label for this gene is yabF [C]

Identifier: 66047025

GI number: 66047025

Start: 4514362

End: 4515162

Strand: Direct

Name: yabF [C]

Synonym: Psyr_3797

Alternate gene names: 66047025

Gene position: 4514362-4515162 (Clockwise)

Preceding gene: 66047023

Following gene: 66047026

Centisome position: 74.08

GC content: 60.3

Gene sequence:

>801_bases
ATGAACGTACTTATTGTCTACGCCCACCCCGAACCGCGCTCGCTGAACGGGTCGTTGAAAGACTTCGCCGTCGATCATCT
GCAGAACAACGGCCATCAGGTGCAGGTGTCCGACCTTTACCAGATGGGCTGGAAGCCGATCATCGACGCCAACGATGCAC
CCGGTCTCGAGAGCAGCAGCCGCTTTGACCCTGCCCTTGAGTCGCAACGCGTATTTGCCGCCGGTATTCAGCCGCCGGAC
ATCGAGGCCGAACAGGCCAGATTGCTCTGGGCAGACGCCGTCATATTTCAGTTTCCGCTCTGGTGGTTTTCGATGCCCGC
GATCATGAAAGGCTGGATAGAGCGGGTGTACGCCTGTGGTTTCGCCTACGGCGTGGGCGAGCACAGCGACCAGCACTGGG
GTGATCGCTACGGTGAAGGAACGCTGGCAGGCAAGCGCGCCATGCTGACGGTGACCATGGGCGGCTGGGATTCCCATTAC
AGCGAGCGTGGCGTAAACGGGGCGCTGAACGACGTGCTTTTTCCTATCCAGCACGGCATCCTGTTCTATCCAGGTTTCGA
TGTGCTCGCGCCCTTCCCCGTGTACCGGGCAGGCAAGGTGGACAGCGCAACCTTTGCGCGGATTTGCGCCGACTACGGCA
ACCGCCTGGATACCCTGTTCACCCTTGAGCCCTTGCCATTTCGCAGACAGAACGACGGTGACTACGAGATCCCGGCACTG
ACCTTGCGTCCTGAGCTTGCAGCGGGTCGGCAGGGACTGGGCATTCACCTTCGTGATGAGGATGGGCCTGCGGATCTTTA
G

Upstream 100 bases:

>100_bases
GGTATTGTTCATGCAAATACCCAGTGTTTGGGAGATTGATTTCCAGCATACCCGAGCGAGTCTGTAGCGTTGCCTCATTA
CCGACAAACCGGAGACTCTC

Downstream 100 bases:

>100_bases
GACAGAGTGTCAGAGGATTGATGAGCAGCGCTCAGCAGCGCATGTACCCCAGACCACACAGAAAAAAGCGGCATACCCGG
TATGCTGCTGTCGGAGCATT

Product: NAD(P)H dehydrogenase (quinone)

Products: NAD(P); reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MNVLIVYAHPEPRSLNGSLKDFAVDHLQNNGHQVQVSDLYQMGWKPIIDANDAPGLESSSRFDPALESQRVFAAGIQPPD
IEAEQARLLWADAVIFQFPLWWFSMPAIMKGWIERVYACGFAYGVGEHSDQHWGDRYGEGTLAGKRAMLTVTMGGWDSHY
SERGVNGALNDVLFPIQHGILFYPGFDVLAPFPVYRAGKVDSATFARICADYGNRLDTLFTLEPLPFRRQNDGDYEIPAL
TLRPELAAGRQGLGIHLRDEDGPADL

Sequences:

>Translated_266_residues
MNVLIVYAHPEPRSLNGSLKDFAVDHLQNNGHQVQVSDLYQMGWKPIIDANDAPGLESSSRFDPALESQRVFAAGIQPPD
IEAEQARLLWADAVIFQFPLWWFSMPAIMKGWIERVYACGFAYGVGEHSDQHWGDRYGEGTLAGKRAMLTVTMGGWDSHY
SERGVNGALNDVLFPIQHGILFYPGFDVLAPFPVYRAGKVDSATFARICADYGNRLDTLFTLEPLPFRRQNDGDYEIPAL
TLRPELAAGRQGLGIHLRDEDGPADL
>Mature_266_residues
MNVLIVYAHPEPRSLNGSLKDFAVDHLQNNGHQVQVSDLYQMGWKPIIDANDAPGLESSSRFDPALESQRVFAAGIQPPD
IEAEQARLLWADAVIFQFPLWWFSMPAIMKGWIERVYACGFAYGVGEHSDQHWGDRYGEGTLAGKRAMLTVTMGGWDSHY
SERGVNGALNDVLFPIQHGILFYPGFDVLAPFPVYRAGKVDSATFARICADYGNRLDTLFTLEPLPFRRQNDGDYEIPAL
TLRPELAAGRQGLGIHLRDEDGPADL

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=226, Percent_Identity=42.0353982300885, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI4505415, Length=225, Percent_Identity=40.8888888888889, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI70995396, Length=225, Percent_Identity=34.2222222222222, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI70995422, Length=225, Percent_Identity=32.4444444444444, Blast_Score=91, Evalue=9e-19,
Organism=Escherichia coli, GI1786231, Length=137, Percent_Identity=32.8467153284672, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787129, Length=124, Percent_Identity=29.8387096774194, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 29637; Mature: 29637

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLIVYAHPEPRSLNGSLKDFAVDHLQNNGHQVQVSDLYQMGWKPIIDANDAPGLESSS
CCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCEEEECCCCCCCCCCCC
RFDPALESQRVFAAGIQPPDIEAEQARLLWADAVIFQFPLWWFSMPAIMKGWIERVYACG
CCCCCHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAYGVGEHSDQHWGDRYGEGTLAGKRAMLTVTMGGWDSHYSERGVNGALNDVLFPIQHGI
HHHCCCCCCCCCCHHHCCCCCCCCCEEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHCCE
LFYPGFDVLAPFPVYRAGKVDSATFARICADYGNRLDTLFTLEPLPFRRQNDGDYEIPAL
EEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEECCEE
TLRPELAAGRQGLGIHLRDEDGPADL
EECCHHHCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MNVLIVYAHPEPRSLNGSLKDFAVDHLQNNGHQVQVSDLYQMGWKPIIDANDAPGLESSS
CCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCEEEECCCCCCCCCCCC
RFDPALESQRVFAAGIQPPDIEAEQARLLWADAVIFQFPLWWFSMPAIMKGWIERVYACG
CCCCCHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAYGVGEHSDQHWGDRYGEGTLAGKRAMLTVTMGGWDSHYSERGVNGALNDVLFPIQHGI
HHHCCCCCCCCCCHHHCCCCCCCCCEEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHCCE
LFYPGFDVLAPFPVYRAGKVDSATFARICADYGNRLDTLFTLEPLPFRRQNDGDYEIPAL
EEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEECCEE
TLRPELAAGRQGLGIHLRDEDGPADL
EECCHHHCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H2; acceptor [C]

Specific reaction: NAD(P)H2 + acceptor = NAD(P) + reduced acceptor [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]