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The map label for this gene is cysM [H]

Identifier: 66046926

GI number: 66046926

Start: 4384397

End: 4385338

Strand: Reverse

Name: cysM [H]

Synonym: Psyr_3697

Alternate gene names: 66046926

Gene position: 4385338-4384397 (Counterclockwise)

Preceding gene: 66046930

Following gene: 66046925

Centisome position: 71.97

GC content: 61.57

Gene sequence:

>942_bases
ATGATAGGCACCCCCCGCAGTCTGGATTGCGAAGACGCCATGACCCTGCAGTATCAAACCATTGCCGATTGCGTCGGCAA
CACCCCGCTGGTGCGTCTGCAACGCATGGCGGGTAATACCAGCAATACCCTCCTGTTGAAACTCGAAGGTAACAACCCCG
CTGGCTCGGTAAAAGACCGCCCGGCCTTGTCGATGATCACCCGCGCCGAGTTGCGCGGCCAGATCCATCCGGGTGACACG
CTGATCGAAGCCACCTCCGGCAATACCGGAATCGCGCTGGCCATGGCTGCGGCGATCAAGGGCTACCGGATGATTCTGAT
CATGCCGGACAACTCCAGTGCCGAACGCAAGGCCGCGATGACCGCCTATGGCGCCGAGCTGATTTCGGTCAGCAAGGATG
ACGGCATGGAAGGTGCCCGTGATCTGGCCGAGCGCATGCAGGCCGAAGGCCGTGGCAAGGTGCTCGATCAGTTTGCCAAT
GGCGACAACCCCGAGGCGCATTACACGTCCACCGGTCCGGAAATCTGGCGGCAGACGGGCGGTACCGTGACCCATTTCGT
CAGTTCGATGGGCACCACCGGCACCATCATGGGCACCTCGCGCTACCTCAAGGAGCAGAATCCCGACGTGCAGATCGTCG
GTCTGCAACCGATGGAGGGCGCTTCGATCCCCGGTATTCGCCGCTGGCCGCAGGAATACCTGCCGAAAATCTATCAGTCG
GACCGTGTCGACCGCATCATCGACATGGGCCAGAGCGAAGCCGAAGACACCATGCGCCGCCTCGCTCGCGAAGAAGGCAT
CTTCTGTGGCGTGTCGTCCGGTGGCTCGGTCGCCGGGGCGTTGCGTATTTCCCGGGAAGTCGAAAACGCCGTGATTGTGG
CGATCATCTGTGACCGAGGCGACCGTTACCTGTCGACCGGCGTCTATGATTCGCCCAACTGA

Upstream 100 bases:

>100_bases
TCTCTATGCAGGGCGGGGTGGCAGCGGAAAAATCGGTGGTTATTCTTTTTGGGAATAAGCAGCGCACTTTGCGTGATATG
GGCTTTGGCCGTTTGCCGTT

Downstream 100 bases:

>100_bases
TGGCCAAGCATGAAAGAGGTTTGCGCTTTCAGCCTGCGGGCGGCGTTAAAACCGTACAGATTCCTGCTGGCAAAAAGCAG
CGGCTGACCATTGAGCGGCT

Product: cysteine synthase B

Products: NA

Alternate protein names: CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MIGTPRSLDCEDAMTLQYQTIADCVGNTPLVRLQRMAGNTSNTLLLKLEGNNPAGSVKDRPALSMITRAELRGQIHPGDT
LIEATSGNTGIALAMAAAIKGYRMILIMPDNSSAERKAAMTAYGAELISVSKDDGMEGARDLAERMQAEGRGKVLDQFAN
GDNPEAHYTSTGPEIWRQTGGTVTHFVSSMGTTGTIMGTSRYLKEQNPDVQIVGLQPMEGASIPGIRRWPQEYLPKIYQS
DRVDRIIDMGQSEAEDTMRRLAREEGIFCGVSSGGSVAGALRISREVENAVIVAIICDRGDRYLSTGVYDSPN

Sequences:

>Translated_313_residues
MIGTPRSLDCEDAMTLQYQTIADCVGNTPLVRLQRMAGNTSNTLLLKLEGNNPAGSVKDRPALSMITRAELRGQIHPGDT
LIEATSGNTGIALAMAAAIKGYRMILIMPDNSSAERKAAMTAYGAELISVSKDDGMEGARDLAERMQAEGRGKVLDQFAN
GDNPEAHYTSTGPEIWRQTGGTVTHFVSSMGTTGTIMGTSRYLKEQNPDVQIVGLQPMEGASIPGIRRWPQEYLPKIYQS
DRVDRIIDMGQSEAEDTMRRLAREEGIFCGVSSGGSVAGALRISREVENAVIVAIICDRGDRYLSTGVYDSPN
>Mature_313_residues
MIGTPRSLDCEDAMTLQYQTIADCVGNTPLVRLQRMAGNTSNTLLLKLEGNNPAGSVKDRPALSMITRAELRGQIHPGDT
LIEATSGNTGIALAMAAAIKGYRMILIMPDNSSAERKAAMTAYGAELISVSKDDGMEGARDLAERMQAEGRGKVLDQFAN
GDNPEAHYTSTGPEIWRQTGGTVTHFVSSMGTTGTIMGTSRYLKEQNPDVQIVGLQPMEGASIPGIRRWPQEYLPKIYQS
DRVDRIIDMGQSEAEDTMRRLAREEGIFCGVSSGGSVAGALRISREVENAVIVAIICDRGDRYLSTGVYDSPN

Specific function: Two Cysteine Synthase Enzymes Are Found. Both Catalyze The Same Reaction. Cysteine Synthase B Can Also Use Thiosulfate In Place Of Sulfide To Give Cysteine Thiosulfonate As A Product. [C]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=306, Percent_Identity=36.9281045751634, Blast_Score=181, Evalue=5e-46,
Organism=Homo sapiens, GI295821200, Length=306, Percent_Identity=36.9281045751634, Blast_Score=181, Evalue=5e-46,
Organism=Homo sapiens, GI4557415, Length=306, Percent_Identity=36.9281045751634, Blast_Score=181, Evalue=5e-46,
Organism=Escherichia coli, GI2367138, Length=290, Percent_Identity=70, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1788754, Length=315, Percent_Identity=40.3174603174603, Blast_Score=191, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17535051, Length=305, Percent_Identity=40, Blast_Score=217, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI17562970, Length=305, Percent_Identity=40, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI115535073, Length=299, Percent_Identity=42.1404682274247, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI32566674, Length=300, Percent_Identity=40.3333333333333, Blast_Score=207, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17561720, Length=304, Percent_Identity=39.8026315789474, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI25147552, Length=317, Percent_Identity=34.0694006309148, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI32566672, Length=212, Percent_Identity=36.3207547169811, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17534315, Length=320, Percent_Identity=33.125, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321594, Length=320, Percent_Identity=37.8125, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6321449, Length=326, Percent_Identity=30.9815950920245, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24643623, Length=313, Percent_Identity=37.3801916932907, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI20129101, Length=313, Percent_Identity=37.3801916932907, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005858
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 33793; Mature: 33793

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00901 CYS_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGTPRSLDCEDAMTLQYQTIADCVGNTPLVRLQRMAGNTSNTLLLKLEGNNPAGSVKDR
CCCCCCCCCCCCHHEEHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC
PALSMITRAELRGQIHPGDTLIEATSGNTGIALAMAAAIKGYRMILIMPDNSSAERKAAM
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHH
TAYGAELISVSKDDGMEGARDLAERMQAEGRGKVLDQFANGDNPEAHYTSTGPEIWRQTG
HHHCHHHEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHCC
GTVTHFVSSMGTTGTIMGTSRYLKEQNPDVQIVGLQPMEGASIPGIRRWPQEYLPKIYQS
CHHHHHHHHCCCCEEEECCHHHHHCCCCCEEEEECCCCCCCCCCCHHCCHHHHHHHHHHC
DRVDRIIDMGQSEAEDTMRRLAREEGIFCGVSSGGSVAGALRISREVENAVIVAIICDRG
CHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHCCCEEEEEEEECCC
DRYLSTGVYDSPN
CCEEECCCCCCCC
>Mature Secondary Structure
MIGTPRSLDCEDAMTLQYQTIADCVGNTPLVRLQRMAGNTSNTLLLKLEGNNPAGSVKDR
CCCCCCCCCCCCHHEEHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC
PALSMITRAELRGQIHPGDTLIEATSGNTGIALAMAAAIKGYRMILIMPDNSSAERKAAM
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHH
TAYGAELISVSKDDGMEGARDLAERMQAEGRGKVLDQFANGDNPEAHYTSTGPEIWRQTG
HHHCHHHEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHCC
GTVTHFVSSMGTTGTIMGTSRYLKEQNPDVQIVGLQPMEGASIPGIRRWPQEYLPKIYQS
CHHHHHHHHCCCCEEEECCHHHHHCCCCCEEEEECCCCCCCCCCCHHCCHHHHHHHHHHC
DRVDRIIDMGQSEAEDTMRRLAREEGIFCGVSSGGSVAGALRISREVENAVIVAIICDRG
CHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHCCCEEEEEEEECCC
DRYLSTGVYDSPN
CCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]