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The map label for this gene is mtnA [H]

Identifier: 66046877

GI number: 66046877

Start: 4333619

End: 4334716

Strand: Reverse

Name: mtnA [H]

Synonym: Psyr_3648

Alternate gene names: 66046877

Gene position: 4334716-4333619 (Counterclockwise)

Preceding gene: 66046883

Following gene: 66046876

Centisome position: 71.13

GC content: 63.84

Gene sequence:

>1098_bases
ATGTTCAAGATGGAGTTGGCGATGCGCGATCGACTGTTGGCTGCGGAGAAAGTTAAGGCCATCGATTGGCGGGACGACGC
TCTGTACCTGCTGGACCAGCGGGTACTGCCGTTCGAGGAAGTCTGGCACCGCTATACCACCGCCGAGGGAGTCGCCGAAG
CGATTCGCACGATGGTCGTGCGCGGGGCGCCGGCTATCGGCATCAGTGCCGCTTATGGTGCTGTGCTGGCCGCACGTGCG
CGTATCGCGCAGGGTGCAGACTGGTATCCGGCGCTGGAAGAGGACATGCAGTTGCTGGCCGATTCGCGCCCGACTGCAGT
GAACCTGTTCTGGGCGCTGAACCGGATGCGTGATCGGCTGATGCGCGTCAAGGATGGCGATGACCCGCTGGCAGCCCTCG
AGGCCGAAGCCGTGGCGATTCACCTGAGCGACCGCGAGGCCAATCTGACCATGGCGCAGCTGGGCGCCGACCTGATCCGC
AAGCACCAGGGCAATCTGCAGACGGTGCTCACCCACTGCAATACCGGGGCACTGGCCACGGGCGGCTTCGGCACGGCGCT
GGGGGTGATTCGCGCGGCGCATCTGGAAGGCATGATCGAGCGGGTCTACGCCGATGAAACACGGCCCTGGCTGCAGGGCT
CGCGGCTGACCGCCTGGGAGCTGGCCAACGAGGGCATTCCGGTGACCCTGAACGCAGATTCCGCCGCGGCGCACCTGATG
CGTACCAAGGGCATCACCTGGGTCATCGTCGGTGCCGACCGCATCACCGCCAACGGTGATGTGGCGAACAAGATCGGTAC
CTATCAGCTCGCCGTTGCCGCCATGCACCACGGGGTGCGCTTCATGGTGGTCGCGCCGAGTTCGACCATCGACATGGAAA
TGGCCAGTGGCGACGACATCGTCATCGAAGAGCGTGACGGTCGCGAACTGCTTGAAGTGGGCGGTCAACGAGTCGGCGCC
GAGGTCGAGGCTTTCAACCCGGTGTTCGATGTGACGCCGGCTGACCTGATCGACGCCATCGTGACTGAAAAGGGCATTGT
CGAGCGTCCCGATACCGCGCGCATGGCTCAATTGATGAGCCGTAAACACCTTCACTGA

Upstream 100 bases:

>100_bases
TGAGAAGGTTTCCATCGTTTATTACGTTGATGACGAAGTATACCCGAGCGTCTTCGCAGGCGGCTCGCTATAATCAGCGG
CTTTTGATGCTGGGTTTCGG

Downstream 100 bases:

>100_bases
GGCTGACAGGCCCGACCCTTCGCCGTTGTGCAATGCGGCTGGACGGGCCTGTAAGCGTTTCTCAGGCGTGTTATGCGTCT
GCGGCTCGCTTTCAGCGCCT

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MFKMELAMRDRLLAAEKVKAIDWRDDALYLLDQRVLPFEEVWHRYTTAEGVAEAIRTMVVRGAPAIGISAAYGAVLAARA
RIAQGADWYPALEEDMQLLADSRPTAVNLFWALNRMRDRLMRVKDGDDPLAALEAEAVAIHLSDREANLTMAQLGADLIR
KHQGNLQTVLTHCNTGALATGGFGTALGVIRAAHLEGMIERVYADETRPWLQGSRLTAWELANEGIPVTLNADSAAAHLM
RTKGITWVIVGADRITANGDVANKIGTYQLAVAAMHHGVRFMVVAPSSTIDMEMASGDDIVIEERDGRELLEVGGQRVGA
EVEAFNPVFDVTPADLIDAIVTEKGIVERPDTARMAQLMSRKHLH

Sequences:

>Translated_365_residues
MFKMELAMRDRLLAAEKVKAIDWRDDALYLLDQRVLPFEEVWHRYTTAEGVAEAIRTMVVRGAPAIGISAAYGAVLAARA
RIAQGADWYPALEEDMQLLADSRPTAVNLFWALNRMRDRLMRVKDGDDPLAALEAEAVAIHLSDREANLTMAQLGADLIR
KHQGNLQTVLTHCNTGALATGGFGTALGVIRAAHLEGMIERVYADETRPWLQGSRLTAWELANEGIPVTLNADSAAAHLM
RTKGITWVIVGADRITANGDVANKIGTYQLAVAAMHHGVRFMVVAPSSTIDMEMASGDDIVIEERDGRELLEVGGQRVGA
EVEAFNPVFDVTPADLIDAIVTEKGIVERPDTARMAQLMSRKHLH
>Mature_365_residues
MFKMELAMRDRLLAAEKVKAIDWRDDALYLLDQRVLPFEEVWHRYTTAEGVAEAIRTMVVRGAPAIGISAAYGAVLAARA
RIAQGADWYPALEEDMQLLADSRPTAVNLFWALNRMRDRLMRVKDGDDPLAALEAEAVAIHLSDREANLTMAQLGADLIR
KHQGNLQTVLTHCNTGALATGGFGTALGVIRAAHLEGMIERVYADETRPWLQGSRLTAWELANEGIPVTLNADSAAAHLM
RTKGITWVIVGADRITANGDVANKIGTYQLAVAAMHHGVRFMVVAPSSTIDMEMASGDDIVIEERDGRELLEVGGQRVGA
EVEAFNPVFDVTPADLIDAIVTEKGIVERPDTARMAQLMSRKHLH

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=351, Percent_Identity=42.4501424501425, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI23943880, Length=345, Percent_Identity=37.9710144927536, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI78000156, Length=167, Percent_Identity=31.7365269461078, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI187607323, Length=167, Percent_Identity=31.7365269461078, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI78000158, Length=167, Percent_Identity=31.7365269461078, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17557462, Length=342, Percent_Identity=37.719298245614, Blast_Score=208, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6325375, Length=383, Percent_Identity=35.509138381201, Blast_Score=198, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21357667, Length=355, Percent_Identity=39.7183098591549, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24651647, Length=355, Percent_Identity=39.7183098591549, Blast_Score=227, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 39938; Mature: 39938

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKMELAMRDRLLAAEKVKAIDWRDDALYLLDQRVLPFEEVWHRYTTAEGVAEAIRTMVV
CEEEHHHHHHHHHHHHHHHEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGAPAIGISAAYGAVLAARARIAQGADWYPALEEDMQLLADSRPTAVNLFWALNRMRDRL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
MRVKDGDDPLAALEAEAVAIHLSDREANLTMAQLGADLIRKHQGNLQTVLTHCNTGALAT
HHCCCCCCCHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEC
GGFGTALGVIRAAHLEGMIERVYADETRPWLQGSRLTAWELANEGIPVTLNADSAAAHLM
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCHHHHHHH
RTKGITWVIVGADRITANGDVANKIGTYQLAVAAMHHGVRFMVVAPSSTIDMEMASGDDI
HHCCCEEEEEECCEEECCCCHHHHCCHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCEE
VIEERDGRELLEVGGQRVGAEVEAFNPVFDVTPADLIDAIVTEKGIVERPDTARMAQLMS
EEECCCCHHHHHHCCHHCCCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RKHLH
HCCCC
>Mature Secondary Structure
MFKMELAMRDRLLAAEKVKAIDWRDDALYLLDQRVLPFEEVWHRYTTAEGVAEAIRTMVV
CEEEHHHHHHHHHHHHHHHEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGAPAIGISAAYGAVLAARARIAQGADWYPALEEDMQLLADSRPTAVNLFWALNRMRDRL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
MRVKDGDDPLAALEAEAVAIHLSDREANLTMAQLGADLIRKHQGNLQTVLTHCNTGALAT
HHCCCCCCCHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEC
GGFGTALGVIRAAHLEGMIERVYADETRPWLQGSRLTAWELANEGIPVTLNADSAAAHLM
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCHHHHHHH
RTKGITWVIVGADRITANGDVANKIGTYQLAVAAMHHGVRFMVVAPSSTIDMEMASGDDI
HHCCCEEEEEECCEEECCCCHHHHCCHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCEE
VIEERDGRELLEVGGQRVGAEVEAFNPVFDVTPADLIDAIVTEKGIVERPDTARMAQLMS
EEECCCCHHHHHHCCHHCCCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RKHLH
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA