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The map label for this gene is serC [H]

Identifier: 66046875

GI number: 66046875

Start: 4329247

End: 4330332

Strand: Reverse

Name: serC [H]

Synonym: Psyr_3646

Alternate gene names: 66046875

Gene position: 4330332-4329247 (Counterclockwise)

Preceding gene: 66046876

Following gene: 66046874

Centisome position: 71.06

GC content: 59.76

Gene sequence:

>1086_bases
ATGAGCAAGCGAGCCTTTAACTTCTGCGCAGGTCCTGCTGCGCTTCCTGAAGCTGTTCTGCTGCGTGCCCAGGCGGAACT
CCTCGACTGGCACGGCAAAGGCCTTTCCGTCATGGAAATGAGCCACCGCAGTGATGAGTTCGTCTCCATTGCCACCAAGG
CCGAGCAGGATCTGCGTGACCTGCTGTCCATTCCTTCGAATTACAAGGTGTTGTTCCTGCAAGGCGGTGCCAGCCAGCAG
TTCGCCCAGATTGCGCTGAACCTGCTGCCTGAAAATGGCAAGGCCGATTACATCGACACCGGCATCTGGTCGCAGAAGGC
TATCGACGAGGCGTCGCGCTACGGCGCAATCAACGTCGCGGCCAGCGCCAAGGCCTACGATTACTTTGCCATTCCCGGCC
AGAACGAGTGGAAGCTGTCCAAGGACGCGGCTTACGTCCACTACGCGCCGAACGAAACCATTGGCGGCCTGGAATTCAAC
TGGATTCCGGAAACCGGCGACGTGCCCCTGGTGGCCGACATGTCTTCGGACATCCTCTCGCGTCCGCTGGATATCTCGCG
TTTCGGCATGATTTACGCCGGCGCCCAGAAGAACATCGGCCCCAGCGGCATCGTGGTGGTGATCATTCGCGAAGACCTGC
TGGGCCGCGCTCGCTCGCTGTGCCCGACCATGCTCGACTACAAGGTCGCGGCCGACAATGGTTCGATGTACAACACGCCG
CCGACCCTGGCCTGGTACCTGTCCGGGCTGGTCTTCGAATGGCTGAAAGAGCAGGGCGGTGTCGAAGCGATCGGCAAGCG
CAACGAAATCAAGCAGCGCACGCTGTATGACTTCATCGACGCCAGCGAGCTGTACAGCAACCCGATCAACAAGCCTGATC
GTTCGTGGATGAACGTCCCGTTCCGTCTGGCTGACGATCGTCTCGACAAGCCGTTCCTGGCCGGTGCCGATGCAAACGGC
CTGCTCAACCTCAAGGGCCATCGTTCGGTAGGCGGCATGCGTGCATCCATCTACAACGCGATCGATATCAACGCCATCAA
CGCGCTGGTGGCCTACATGAAAGACTTCGAGAAGGAGCACGGCTGA

Upstream 100 bases:

>100_bases
ATTCCCGCAAGGAGCTGCCAGTCGCTGCGGCGTCTGTCTGCTCGTGGCAAGCAACCAGAAACAAGCGCGTACAGACCCAA
CGTATTTGACGAGAGTGGAT

Downstream 100 bases:

>100_bases
TGTCCGAGCAAGAACTCAAGGCGCTTCGCGTCCGTATCGACAGCCTCGATGAGAAGGTTCTGGAACTGATCAGCGAGCGT
GCCCGCTGTGCCCAAGAAGT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSKRAFNFCAGPAALPEAVLLRAQAELLDWHGKGLSVMEMSHRSDEFVSIATKAEQDLRDLLSIPSNYKVLFLQGGASQQ
FAQIALNLLPENGKADYIDTGIWSQKAIDEASRYGAINVAASAKAYDYFAIPGQNEWKLSKDAAYVHYAPNETIGGLEFN
WIPETGDVPLVADMSSDILSRPLDISRFGMIYAGAQKNIGPSGIVVVIIREDLLGRARSLCPTMLDYKVAADNGSMYNTP
PTLAWYLSGLVFEWLKEQGGVEAIGKRNEIKQRTLYDFIDASELYSNPINKPDRSWMNVPFRLADDRLDKPFLAGADANG
LLNLKGHRSVGGMRASIYNAIDINAINALVAYMKDFEKEHG

Sequences:

>Translated_361_residues
MSKRAFNFCAGPAALPEAVLLRAQAELLDWHGKGLSVMEMSHRSDEFVSIATKAEQDLRDLLSIPSNYKVLFLQGGASQQ
FAQIALNLLPENGKADYIDTGIWSQKAIDEASRYGAINVAASAKAYDYFAIPGQNEWKLSKDAAYVHYAPNETIGGLEFN
WIPETGDVPLVADMSSDILSRPLDISRFGMIYAGAQKNIGPSGIVVVIIREDLLGRARSLCPTMLDYKVAADNGSMYNTP
PTLAWYLSGLVFEWLKEQGGVEAIGKRNEIKQRTLYDFIDASELYSNPINKPDRSWMNVPFRLADDRLDKPFLAGADANG
LLNLKGHRSVGGMRASIYNAIDINAINALVAYMKDFEKEHG
>Mature_360_residues
SKRAFNFCAGPAALPEAVLLRAQAELLDWHGKGLSVMEMSHRSDEFVSIATKAEQDLRDLLSIPSNYKVLFLQGGASQQF
AQIALNLLPENGKADYIDTGIWSQKAIDEASRYGAINVAASAKAYDYFAIPGQNEWKLSKDAAYVHYAPNETIGGLEFNW
IPETGDVPLVADMSSDILSRPLDISRFGMIYAGAQKNIGPSGIVVVIIREDLLGRARSLCPTMLDYKVAADNGSMYNTPP
TLAWYLSGLVFEWLKEQGGVEAIGKRNEIKQRTLYDFIDASELYSNPINKPDRSWMNVPFRLADDRLDKPFLAGADANGL
LNLKGHRSVGGMRASIYNAIDINAINALVAYMKDFEKEHG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=365, Percent_Identity=49.8630136986301, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI10863955, Length=360, Percent_Identity=44.4444444444444, Blast_Score=317, Evalue=2e-86,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=56.145251396648, Blast_Score=411, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17506897, Length=364, Percent_Identity=44.7802197802198, Blast_Score=327, Evalue=6e-90,
Organism=Saccharomyces cerevisiae, GI6324758, Length=381, Percent_Identity=39.1076115485564, Blast_Score=254, Evalue=2e-68,
Organism=Drosophila melanogaster, GI21356589, Length=361, Percent_Identity=49.584487534626, Blast_Score=366, Evalue=1e-101,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39807; Mature: 39675

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRAFNFCAGPAALPEAVLLRAQAELLDWHGKGLSVMEMSHRSDEFVSIATKAEQDLRD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHEEHHHHHHHHHHH
LLSIPSNYKVLFLQGGASQQFAQIALNLLPENGKADYIDTGIWSQKAIDEASRYGAINVA
HHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHCCEEEEE
ASAKAYDYFAIPGQNEWKLSKDAAYVHYAPNETIGGLEFNWIPETGDVPLVADMSSDILS
ECCCCEEEEECCCCCCCEECCCCEEEEECCCCCCCCEEEEEECCCCCCCEEECCCHHHHH
RPLDISRFGMIYAGAQKNIGPSGIVVVIIREDLLGRARSLCPTMLDYKVAADNGSMYNTP
CCCCHHHCCEEEECCCCCCCCCCEEEEEECCHHHHHHHHHCHHHHCEEEECCCCCCCCCC
PTLAWYLSGLVFEWLKEQGGVEAIGKRNEIKQRTLYDFIDASELYSNPINKPDRSWMNVP
CHHHHHHHHHHHHHHHHCCCEEHHCCHHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHCCC
FRLADDRLDKPFLAGADANGLLNLKGHRSVGGMRASIYNAIDINAINALVAYMKDFEKEH
EEECCCCCCCCEEECCCCCCEEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCC
G
C
>Mature Secondary Structure 
SKRAFNFCAGPAALPEAVLLRAQAELLDWHGKGLSVMEMSHRSDEFVSIATKAEQDLRD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHEEHHHHHHHHHHH
LLSIPSNYKVLFLQGGASQQFAQIALNLLPENGKADYIDTGIWSQKAIDEASRYGAINVA
HHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHCCEEEEE
ASAKAYDYFAIPGQNEWKLSKDAAYVHYAPNETIGGLEFNWIPETGDVPLVADMSSDILS
ECCCCEEEEECCCCCCCEECCCCEEEEECCCCCCCCEEEEEECCCCCCCEEECCCHHHHH
RPLDISRFGMIYAGAQKNIGPSGIVVVIIREDLLGRARSLCPTMLDYKVAADNGSMYNTP
CCCCHHHCCEEEECCCCCCCCCCEEEEEECCHHHHHHHHHCHHHHCEEEECCCCCCCCCC
PTLAWYLSGLVFEWLKEQGGVEAIGKRNEIKQRTLYDFIDASELYSNPINKPDRSWMNVP
CHHHHHHHHHHHHHHHHCCCEEHHCCHHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHCCC
FRLADDRLDKPFLAGADANGLLNLKGHRSVGGMRASIYNAIDINAINALVAYMKDFEKEH
EEECCCCCCCCEEECCCCCCEEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]