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The map label for this gene is capD [H]

Identifier: 66046865

GI number: 66046865

Start: 4316968

End: 4318962

Strand: Reverse

Name: capD [H]

Synonym: Psyr_3636

Alternate gene names: 66046865

Gene position: 4318962-4316968 (Counterclockwise)

Preceding gene: 66046866

Following gene: 66046864

Centisome position: 70.88

GC content: 56.69

Gene sequence:

>1995_bases
ATGAGCAGGTTGCGGGCCAGGTTACTGGCTCTACCACGCCGCAAAAAACGAATAATTCAGGTTGCTGCCGACGTTATTCT
GGTCTGGCTGGCTCTGTGGATGGCGTTTGTCGTACGACTGGGTATCGATGAGCTGATCAATCCTCTCGAGAAGCACACCT
GGCTGTTCATCAGTGCGCCTGTTGCGGCTATCCCGCTGTTCATCCGGTTCGGCATGTACCGCGCAGTGATGCGCTATTTC
GGCAATGATGCGCTGATTGCCATCATCAAGGCCGTCACGATGTCGTCGTTGATCCTTGGTTGTATGGTTTACGTTTACAG
TAATCACCAGCAATTGGTCCCGCGCTCGGTGATCTTCAATTACTGGTGGCTGAGCATGGTCATGATTGGCGGTCTGCGAC
TGGCCATGCGGCAGTACTTTCTCGGCGACTGGTTCGCTGCAGCGCAGCACGTGCCCTTCGCCAAGAGCGACAACGGTTTG
CAGAAGGTCGCCATTTACGGCGCTGGTGCTGCGGGAAACCAGTTGGTCGCTGCATTGCGCATGGGGCGTCTGATGCATCC
GGTGGCGTTCATCGATGATGATGAGTCGATTTCCAACCGGGTCATTTCCGGCCTTCAGGTCTACAAACCGCGAAACATCC
AGCGAATGATAGATTCCACGGGGGCTCAGGAAATCCTGTTGGCAATCCCGTCATCGTCGCGTGGGCGACGTCGGGAAATC
CTCGGTTTTCTGGAAGGCTTTCCGCTGCACGTACGAAGCGTTCCGGGTTTCATGGACCTGGCCGCTGGCAGGGTCAAGGT
CGACGACCTTCAGGAAGTCGACATCGCAGACCTTCTGGGGCGTGATGCAGTCCCGGCCCGCGATAACCTGCTTGAGCACT
GCATCAAGGGCAAAACGGTGCTGGTGACCGGCGCAGGCGGCTCGATCGGTTCTGAACTGTGCCGACAGATACTGCTGCTG
AAACCTACCCAGTTACTGTTGCTGGACCATAGCGAGTTCAATCTCTACAGCATTCTCTCCGAGCTTGAACAGCGCTCGGC
TCGCGAGTCACTCTCGGTTAAATTGCTGCCCATACTCGGTTCGGTGCGCAACCACCCCAAACTGCTGTCGATCATGAAAA
CCTGGAAAGTCGACACGGTCTATCACGCTGCGGCCTACAAGCATGTGCCGATGGTCGAGCACAATATTGCCGAAGGCGTC
ATCAACAATGTCGTGGGTACGCTCAATACCGCCCAGGCGGCGTTGCAGGCAGGGGTGTCCAACTTTGTCCTGATCTCCAC
AGACAAGGCGGTCCGCCCGACCAATGTGATGGGCAGCACCAAACGCCTCGCCGAATTGATATTGCAGGCACTGAGCCGCG
AAACCGCGCCAGTGATCTTCGGTGACAAGGCCAATGTCTATCAGGTCAACAAGACCCGCTTTACCATGGTTCGCTTCGGC
AACGTGCTGGGCTCGTCCGGTTCGGTGATTCCGCTGTTCCACAAGCAGATCCAGTCAGGCGGGCCGCTGACGGTGACGCA
TCCCAAGATCACCCGCTATTTCATGACCATCCCCGAAGCCGCTCAGTTGGTCATTCAGGCGGGCTCCATGGGGCATGGCG
GCGACGTTTTCGTTCTCGATATGGGTGAGCCGGTCAAGATTGTCGAACTGGCCGAGAAGATGATCCACCTGTCCGGTCTG
GCCATTCGCTCGGAGAAAAACCCGCACGGTGATATCTCCATCGAGTTCACCGGGCTGCGTCCTGGCGAAAAACTCTATGA
AGAGCTGTTGATCGGCGACAACGTGGTTGCCACCGAGCACCCGATGATCATGAGTGCAAACGAAGATTGCCTGCCGTGGG
ATGTATTGAAAGGCCGCCTGACAAAACTGCTGGATGCGGTCGACCGCGACGATTACACCAGCGTGCGTCAGTTGCTGCGC
GAAACGGTAAACGGTTATACGCCAGAGGGTGAAATCGTTGACTGGATGTATCAGGAACGCAGCGGCGAAACGTGA

Upstream 100 bases:

>100_bases
ACGAAGTGTTTTTCTGGTTGTCTCAGACACGTAGCTGTTTCACTGATGCCGATTTCAGGTCATGTTGCAACCGGTAGCAT
AACGGAGCATAAAAAAATTG

Downstream 100 bases:

>100_bases
TTTCATCCGTGCTGTCGGGGTGCCGGGCAGAGGCGGAAATACGTTGAACGATCCGGCAACAGGCAGCAACGCTCAACTGC
TTTTCCAAGGGGGGACGCTG

Product: polysaccharide biosynthesis protein CapD

Products: UDPglucoseal [C]

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MSRLRARLLALPRRKKRIIQVAADVILVWLALWMAFVVRLGIDELINPLEKHTWLFISAPVAAIPLFIRFGMYRAVMRYF
GNDALIAIIKAVTMSSLILGCMVYVYSNHQQLVPRSVIFNYWWLSMVMIGGLRLAMRQYFLGDWFAAAQHVPFAKSDNGL
QKVAIYGAGAAGNQLVAALRMGRLMHPVAFIDDDESISNRVISGLQVYKPRNIQRMIDSTGAQEILLAIPSSSRGRRREI
LGFLEGFPLHVRSVPGFMDLAAGRVKVDDLQEVDIADLLGRDAVPARDNLLEHCIKGKTVLVTGAGGSIGSELCRQILLL
KPTQLLLLDHSEFNLYSILSELEQRSARESLSVKLLPILGSVRNHPKLLSIMKTWKVDTVYHAAAYKHVPMVEHNIAEGV
INNVVGTLNTAQAALQAGVSNFVLISTDKAVRPTNVMGSTKRLAELILQALSRETAPVIFGDKANVYQVNKTRFTMVRFG
NVLGSSGSVIPLFHKQIQSGGPLTVTHPKITRYFMTIPEAAQLVIQAGSMGHGGDVFVLDMGEPVKIVELAEKMIHLSGL
AIRSEKNPHGDISIEFTGLRPGEKLYEELLIGDNVVATEHPMIMSANEDCLPWDVLKGRLTKLLDAVDRDDYTSVRQLLR
ETVNGYTPEGEIVDWMYQERSGET

Sequences:

>Translated_664_residues
MSRLRARLLALPRRKKRIIQVAADVILVWLALWMAFVVRLGIDELINPLEKHTWLFISAPVAAIPLFIRFGMYRAVMRYF
GNDALIAIIKAVTMSSLILGCMVYVYSNHQQLVPRSVIFNYWWLSMVMIGGLRLAMRQYFLGDWFAAAQHVPFAKSDNGL
QKVAIYGAGAAGNQLVAALRMGRLMHPVAFIDDDESISNRVISGLQVYKPRNIQRMIDSTGAQEILLAIPSSSRGRRREI
LGFLEGFPLHVRSVPGFMDLAAGRVKVDDLQEVDIADLLGRDAVPARDNLLEHCIKGKTVLVTGAGGSIGSELCRQILLL
KPTQLLLLDHSEFNLYSILSELEQRSARESLSVKLLPILGSVRNHPKLLSIMKTWKVDTVYHAAAYKHVPMVEHNIAEGV
INNVVGTLNTAQAALQAGVSNFVLISTDKAVRPTNVMGSTKRLAELILQALSRETAPVIFGDKANVYQVNKTRFTMVRFG
NVLGSSGSVIPLFHKQIQSGGPLTVTHPKITRYFMTIPEAAQLVIQAGSMGHGGDVFVLDMGEPVKIVELAEKMIHLSGL
AIRSEKNPHGDISIEFTGLRPGEKLYEELLIGDNVVATEHPMIMSANEDCLPWDVLKGRLTKLLDAVDRDDYTSVRQLLR
ETVNGYTPEGEIVDWMYQERSGET
>Mature_663_residues
SRLRARLLALPRRKKRIIQVAADVILVWLALWMAFVVRLGIDELINPLEKHTWLFISAPVAAIPLFIRFGMYRAVMRYFG
NDALIAIIKAVTMSSLILGCMVYVYSNHQQLVPRSVIFNYWWLSMVMIGGLRLAMRQYFLGDWFAAAQHVPFAKSDNGLQ
KVAIYGAGAAGNQLVAALRMGRLMHPVAFIDDDESISNRVISGLQVYKPRNIQRMIDSTGAQEILLAIPSSSRGRRREIL
GFLEGFPLHVRSVPGFMDLAAGRVKVDDLQEVDIADLLGRDAVPARDNLLEHCIKGKTVLVTGAGGSIGSELCRQILLLK
PTQLLLLDHSEFNLYSILSELEQRSARESLSVKLLPILGSVRNHPKLLSIMKTWKVDTVYHAAAYKHVPMVEHNIAEGVI
NNVVGTLNTAQAALQAGVSNFVLISTDKAVRPTNVMGSTKRLAELILQALSRETAPVIFGDKANVYQVNKTRFTMVRFGN
VLGSSGSVIPLFHKQIQSGGPLTVTHPKITRYFMTIPEAAQLVIQAGSMGHGGDVFVLDMGEPVKIVELAEKMIHLSGLA
IRSEKNPHGDISIEFTGLRPGEKLYEELLIGDNVVATEHPMIMSANEDCLPWDVLKGRLTKLLDAVDRDDYTSVRQLLRE
TVNGYTPEGEIVDWMYQERSGET

Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 73661; Mature: 73530

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLRARLLALPRRKKRIIQVAADVILVWLALWMAFVVRLGIDELINPLEKHTWLFISAP
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCEEEEEECC
VAAIPLFIRFGMYRAVMRYFGNDALIAIIKAVTMSSLILGCMVYVYSNHQQLVPRSVIFN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHH
YWWLSMVMIGGLRLAMRQYFLGDWFAAAQHVPFAKSDNGLQKVAIYGAGAAGNQLVAALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHH
MGRLMHPVAFIDDDESISNRVISGLQVYKPRNIQRMIDSTGAQEILLAIPSSSRGRRREI
HHHHHCCEEEECCCHHHHHHHHHCHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHH
LGFLEGFPLHVRSVPGFMDLAAGRVKVDDLQEVDIADLLGRDAVPARDNLLEHCIKGKTV
HHHHCCCCEEEECCCCHHHHCCCCEEECCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCEE
LVTGAGGSIGSELCRQILLLKPTQLLLLDHSEFNLYSILSELEQRSARESLSVKLLPILG
EEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEHHHH
SVRNHPKLLSIMKTWKVDTVYHAAAYKHVPMVEHNIAEGVINNVVGTLNTAQAALQAGVS
CCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NFVLISTDKAVRPTNVMGSTKRLAELILQALSRETAPVIFGDKANVYQVNKTRFTMVRFG
CEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCEEEHEEHH
NVLGSSGSVIPLFHKQIQSGGPLTVTHPKITRYFMTIPEAAQLVIQAGSMGHGGDVFVLD
HHHCCCCCEEHHHHHHHCCCCCEEEECHHHHHHHEECCHHHHHHHHCCCCCCCCCEEEEE
MGEPVKIVELAEKMIHLSGLAIRSEKNPHGDISIEFTGLRPGEKLYEELLIGDNVVATEH
CCCCHHHHHHHHHHHHHHCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEECCC
PMIMSANEDCLPWDVLKGRLTKLLDAVDRDDYTSVRQLLRETVNGYTPEGEIVDWMYQER
CEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
SGET
CCCC
>Mature Secondary Structure 
SRLRARLLALPRRKKRIIQVAADVILVWLALWMAFVVRLGIDELINPLEKHTWLFISAP
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCEEEEEECC
VAAIPLFIRFGMYRAVMRYFGNDALIAIIKAVTMSSLILGCMVYVYSNHQQLVPRSVIFN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHH
YWWLSMVMIGGLRLAMRQYFLGDWFAAAQHVPFAKSDNGLQKVAIYGAGAAGNQLVAALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHH
MGRLMHPVAFIDDDESISNRVISGLQVYKPRNIQRMIDSTGAQEILLAIPSSSRGRRREI
HHHHHCCEEEECCCHHHHHHHHHCHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHH
LGFLEGFPLHVRSVPGFMDLAAGRVKVDDLQEVDIADLLGRDAVPARDNLLEHCIKGKTV
HHHHCCCCEEEECCCCHHHHCCCCEEECCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCEE
LVTGAGGSIGSELCRQILLLKPTQLLLLDHSEFNLYSILSELEQRSARESLSVKLLPILG
EEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEHHHH
SVRNHPKLLSIMKTWKVDTVYHAAAYKHVPMVEHNIAEGVINNVVGTLNTAQAALQAGVS
CCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NFVLISTDKAVRPTNVMGSTKRLAELILQALSRETAPVIFGDKANVYQVNKTRFTMVRFG
CEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCEEEHEEHH
NVLGSSGSVIPLFHKQIQSGGPLTVTHPKITRYFMTIPEAAQLVIQAGSMGHGGDVFVLD
HHHCCCCCEEHHHHHHHCCCCCEEEECHHHHHHHEECCHHHHHHHHCCCCCCCCCEEEEE
MGEPVKIVELAEKMIHLSGLAIRSEKNPHGDISIEFTGLRPGEKLYEELLIGDNVVATEH
CCCCHHHHHHHHHHHHHHCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEECCC
PMIMSANEDCLPWDVLKGRLTKLLDAVDRDDYTSVRQLLRETVNGYTPEGEIVDWMYQER
CEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
SGET
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961465 [H]