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The map label for this gene is qseC [H]

Identifier: 66046820

GI number: 66046820

Start: 4272113

End: 4273462

Strand: Direct

Name: qseC [H]

Synonym: Psyr_3591

Alternate gene names: 66046820

Gene position: 4272113-4273462 (Clockwise)

Preceding gene: 66046819

Following gene: 66046822

Centisome position: 70.11

GC content: 64.15

Gene sequence:

>1350_bases
GTGCGTTCATTGTTCTGGCGAATCCTGGCCAGCTTCTGGCTGGCCATCGCTCTGGTAGGCGGCCTGTCGGTGCTCATGGG
GCATATGCTCAATCAGGATGCGTGGATCCTCAGTCGTCATCCGGTGCTCAACTCGTTGCCCGAACAGTGGACGCAACGCT
TCGAGGACAAGGGCGCGGATAACGCTCAGGAATTTCTTCAGGACATCAAACGACGCAATCGTATCGACACGCAAGTGCTC
AGCGACAGCGGCGAGCCGATGGTGCGCGGCACCTTCCCGCCCCGCGCCGCAGCCCTGGAAGCGCGGCAGCGGGAAGACGA
CGATCAGGGGCGCAAACTGCCCTGGCGCCGCCTGGCCACCGAGTACAGCAGCCCGAAGACCGGCGAAACCTACCTGTTTA
TCTACCGCGTTCCGCACCCGGAGCTCGACGAGTGGCACCGTCAGAGTCTGATGTGGCCGTTGAGCGCGCTGGGCATTGCC
CTGGTGGTGCTGACCCTGTTCAGCCTGTTCGTGACGCTGTCGATTACCCGACCGCTGAGCCGCCTGCGCGGCGCAGTGTA
CGACCTGGGGCAAACCAGCTATCAACAGCACAGCCTCGGACAGCTGGCCAACCGCCGTGACGAATTCGGCGTGCTGGCCA
AGGACTTCAACCGCATGGGTGCGCGCCTGCAAAGCCTGATTGGCAGCCAGCGCCAGTTGCTGCGCGATGTGTCTCATGAA
CTGCGCTCACCGCTGGCCCGGTTGCGCATCGCTCTGGCGCTGGCGGAACGCGCGGAGCCTGCCGAGCGTGAAAAGCTCTG
GCCACGGCTGGGTCGTGAATGTGACCGGCTGGAGGCGTTGATCAGCGAGATTCTGGCCCTCGCACGCCTCGACGCCGAGC
TTCGTGGCCCTGAGCCCGTCGACATCGAAGCCCTGCTGCAGCGCCTGAAGAGTGACACACAGCTGGACGGTGTCGACCAG
AATATTCGCGTCGAGGTGCAGGACAACCTGCAGTTCAAAGGCTGGCCGGACATGATCGAACGTGCGCTGGACAACCTGCT
GCGCAACGCGCTGCGCTTCAACCCGAGCGGCCAGAGCATCGATCTGCAGGCAACGCTGGTGGGCGATCACATCCGTCTGA
GCGTTCGCGATCATGGCCCGGGGGTTGCCGACGAACACCTGACACAACTGGGCGAGCCGTTTTACCGCGCCCCCGGCCAG
ACCACGCCGGGTCACGGTCTGGGGCTGGCGATCGCCAAACGCGCAGCGGAACGACATGGCGGCACTCTGATGTTGGGCAA
TCACCCGGACGGCGGGTTTATCGCCACGCTGGATCTGCCCAGAGAGCCGCTCGGTTCATCGTCGGTCTGA

Upstream 100 bases:

>100_bases
CAAAAACGCTGTAACCATCAGGCCTCGCGGCCCGGTGAGTTGAACACAACCCGGCATGCGCGCGCATGCCGGGCTTTTTT
ACTGAGACCGAGGAAATCCC

Downstream 100 bases:

>100_bases
TCAGCCCTGCCACTCGCTGACAAACCCGCCCGTATCGACTTTTGGTGCTTCGCGCGGCGGGTTCAGCGGGGTGCCCAGAT
ACAGAAAGCCGAGCACTTCT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MRSLFWRILASFWLAIALVGGLSVLMGHMLNQDAWILSRHPVLNSLPEQWTQRFEDKGADNAQEFLQDIKRRNRIDTQVL
SDSGEPMVRGTFPPRAAALEARQREDDDQGRKLPWRRLATEYSSPKTGETYLFIYRVPHPELDEWHRQSLMWPLSALGIA
LVVLTLFSLFVTLSITRPLSRLRGAVYDLGQTSYQQHSLGQLANRRDEFGVLAKDFNRMGARLQSLIGSQRQLLRDVSHE
LRSPLARLRIALALAERAEPAEREKLWPRLGRECDRLEALISEILALARLDAELRGPEPVDIEALLQRLKSDTQLDGVDQ
NIRVEVQDNLQFKGWPDMIERALDNLLRNALRFNPSGQSIDLQATLVGDHIRLSVRDHGPGVADEHLTQLGEPFYRAPGQ
TTPGHGLGLAIAKRAAERHGGTLMLGNHPDGGFIATLDLPREPLGSSSV

Sequences:

>Translated_449_residues
MRSLFWRILASFWLAIALVGGLSVLMGHMLNQDAWILSRHPVLNSLPEQWTQRFEDKGADNAQEFLQDIKRRNRIDTQVL
SDSGEPMVRGTFPPRAAALEARQREDDDQGRKLPWRRLATEYSSPKTGETYLFIYRVPHPELDEWHRQSLMWPLSALGIA
LVVLTLFSLFVTLSITRPLSRLRGAVYDLGQTSYQQHSLGQLANRRDEFGVLAKDFNRMGARLQSLIGSQRQLLRDVSHE
LRSPLARLRIALALAERAEPAEREKLWPRLGRECDRLEALISEILALARLDAELRGPEPVDIEALLQRLKSDTQLDGVDQ
NIRVEVQDNLQFKGWPDMIERALDNLLRNALRFNPSGQSIDLQATLVGDHIRLSVRDHGPGVADEHLTQLGEPFYRAPGQ
TTPGHGLGLAIAKRAAERHGGTLMLGNHPDGGFIATLDLPREPLGSSSV
>Mature_449_residues
MRSLFWRILASFWLAIALVGGLSVLMGHMLNQDAWILSRHPVLNSLPEQWTQRFEDKGADNAQEFLQDIKRRNRIDTQVL
SDSGEPMVRGTFPPRAAALEARQREDDDQGRKLPWRRLATEYSSPKTGETYLFIYRVPHPELDEWHRQSLMWPLSALGIA
LVVLTLFSLFVTLSITRPLSRLRGAVYDLGQTSYQQHSLGQLANRRDEFGVLAKDFNRMGARLQSLIGSQRQLLRDVSHE
LRSPLARLRIALALAERAEPAEREKLWPRLGRECDRLEALISEILALARLDAELRGPEPVDIEALLQRLKSDTQLDGVDQ
NIRVEVQDNLQFKGWPDMIERALDNLLRNALRFNPSGQSIDLQATLVGDHIRLSVRDHGPGVADEHLTQLGEPFYRAPGQ
TTPGHGLGLAIAKRAAERHGGTLMLGNHPDGGFIATLDLPREPLGSSSV

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=233, Percent_Identity=36.0515021459227, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787894, Length=327, Percent_Identity=32.7217125382263, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790346, Length=305, Percent_Identity=30.8196721311475, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1786600, Length=249, Percent_Identity=31.3253012048193, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=32.0987654320988, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786783, Length=239, Percent_Identity=30.9623430962343, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790861, Length=308, Percent_Identity=30.1948051948052, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789808, Length=306, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=31.4553990610329, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790551, Length=286, Percent_Identity=27.6223776223776, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=28.4444444444444, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=28.1512605042017, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=325, Percent_Identity=23.6923076923077, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=294, Percent_Identity=25.8503401360544, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=232, Percent_Identity=27.1551724137931, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=273, Percent_Identity=27.8388278388278, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081816, Length=280, Percent_Identity=27.1428571428571, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787374, Length=233, Percent_Identity=26.1802575107296, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=25.974025974026, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=219, Percent_Identity=24.2009132420091, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50562; Mature: 50562

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLFWRILASFWLAIALVGGLSVLMGHMLNQDAWILSRHPVLNSLPEQWTQRFEDKGAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCC
NAQEFLQDIKRRNRIDTQVLSDSGEPMVRGTFPPRAAALEARQREDDDQGRKLPWRRLAT
CHHHHHHHHHHCCCHHHHHHCCCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
EYSSPKTGETYLFIYRVPHPELDEWHRQSLMWPLSALGIALVVLTLFSLFVTLSITRPLS
HCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLRGAVYDLGQTSYQQHSLGQLANRRDEFGVLAKDFNRMGARLQSLIGSQRQLLRDVSHE
HHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRSPLARLRIALALAERAEPAEREKLWPRLGRECDRLEALISEILALARLDAELRGPEPV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DIEALLQRLKSDTQLDGVDQNIRVEVQDNLQFKGWPDMIERALDNLLRNALRFNPSGQSI
CHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
DLQATLVGDHIRLSVRDHGPGVADEHLTQLGEPFYRAPGQTTPGHGLGLAIAKRAAERHG
EEEEEEECCEEEEEEECCCCCCCHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHCC
GTLMLGNHPDGGFIATLDLPREPLGSSSV
CEEEECCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRSLFWRILASFWLAIALVGGLSVLMGHMLNQDAWILSRHPVLNSLPEQWTQRFEDKGAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCC
NAQEFLQDIKRRNRIDTQVLSDSGEPMVRGTFPPRAAALEARQREDDDQGRKLPWRRLAT
CHHHHHHHHHHCCCHHHHHHCCCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
EYSSPKTGETYLFIYRVPHPELDEWHRQSLMWPLSALGIALVVLTLFSLFVTLSITRPLS
HCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLRGAVYDLGQTSYQQHSLGQLANRRDEFGVLAKDFNRMGARLQSLIGSQRQLLRDVSHE
HHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRSPLARLRIALALAERAEPAEREKLWPRLGRECDRLEALISEILALARLDAELRGPEPV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DIEALLQRLKSDTQLDGVDQNIRVEVQDNLQFKGWPDMIERALDNLLRNALRFNPSGQSI
CHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
DLQATLVGDHIRLSVRDHGPGVADEHLTQLGEPFYRAPGQTTPGHGLGLAIAKRAAERHG
EEEEEEECCEEEEEEECCCCCCCHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHCC
GTLMLGNHPDGGFIATLDLPREPLGSSSV
CEEEECCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]