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The map label for this gene is argD [H]

Identifier: 66046794

GI number: 66046794

Start: 4246480

End: 4247697

Strand: Reverse

Name: argD [H]

Synonym: Psyr_3565

Alternate gene names: 66046794

Gene position: 4247697-4246480 (Counterclockwise)

Preceding gene: 66046795

Following gene: 66046793

Centisome position: 69.71

GC content: 61.9

Gene sequence:

>1218_bases
ATGTCCGTTGAGCATGCTGCGGTGCAACGCGCCGATTTCGACCAGGTAATGGTCCCCAATTACGCCCCGGCCGGGTTCAT
CCCTGTGCGCGGTGCGGGCTCCCGGGTCTGGGATCAGGCGGGGCGCGAACTGGTGGATTTCTCGGGCGGGATCGCCGTCA
ACGTATTGGGCCACTGCCACCCGGCGCTGGTCGGTGCCTTGACCGAGCAGGCCAATAACCTCTGGCATGTGTCCAACGTC
TTCACCAACGAGCCGACCCTGCGCCTGGCGAAAAAACTGGTGGATGCGACGTTCGCCGAGCGCGTGTTCTTCTGTAACTC
CGGTGCGGAAGCCAACGAAGCCGCCTTCAAGCTGGCACGTCGTGTGGCGCATGACCAGTACGGCCCGGAAAAGTACGAAA
TCATCGCGGCGCTGAACAGTTTTCATGGCCGTACCCTGTTCACCGTCAGCGTCGGTGGGCAGCCGAAGTACTCCGATGGT
TTCGGGCCGAAGATCACCGGCATCAGCCATGTGCCGTACAACGACCTCGACGCACTGAAGGCCGCTGTGACCGACAAGAC
CTGTGCCGTGGTGCTGGAGCCGATCCAGGGCGAGGGCGGTGTTCTGCCGGGTCAGCTGGAATACCTGCAAGGTGCGCGCA
AACTGTGTGACGAGCACAACGCCCTGCTGGTGTTCGATGAAGTGCAGAGCGGCATGGGCCGTAGCGGTCATCTGTTCGCC
TACATGCATTACGGCGTGACCCCGGACATCCTTTCCAGCGCCAAGAGCATCGGCGGAGGTTTCCCGCTGGCGGCGATGTT
GACCACTGAAAAGCTCGCCAGGCACTTTGCGGTCGGCGTTCACGGCACCACCTATGGCGGCAACCCGCTGGCGTGTGCGG
TCGGTGAGGCGGTGATCGACGTGATCAATACGCCTGAAGTGCTGGCTGGCGTACAGCGCAAGCATCAGCAGTTCAAGACC
CGTCTGCAAAGCATTGGCCAGCAATACGGCGTGTTCAGCGAAGTGCGCGGTCTGGGTCTGCTGATCGGTTGCGTGTTGTC
CGATGCCTGGAAGGGCAAGGCCAAGGACATCTTCAATGCGGCCGAGGCTCAGGACCTGATGATCCTGCAGGCCGGCCCTG
ACGTGATTCGTTTCGCGCCGAGCCTGGTGATTGAAGACGCGGACATCGAAGAGGGCCTGAACCGCTTTGAACGCGCCATC
GCCCAACTGACATCCTGA

Upstream 100 bases:

>100_bases
ACAAGTTGTCGCCTGGCGGCAAGGCCGAACACAATTCAGTCCTTACAATCTTTCCATCGCTCGCCAGTTTCAGGCAGGCG
TTCCTCATCAGGAGACTCCG

Downstream 100 bases:

>100_bases
CTCGCTTGCAGCCTTGCGGCGTCCGCCTGATGGCGGGCGCCGCACCTGTTTCCTGCGCCATGCGGCCTGACGCCGTGTGG
TGCTTTACTAGCGCCGGTCG

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT 1 [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSVEHAAVQRADFDQVMVPNYAPAGFIPVRGAGSRVWDQAGRELVDFSGGIAVNVLGHCHPALVGALTEQANNLWHVSNV
FTNEPTLRLAKKLVDATFAERVFFCNSGAEANEAAFKLARRVAHDQYGPEKYEIIAALNSFHGRTLFTVSVGGQPKYSDG
FGPKITGISHVPYNDLDALKAAVTDKTCAVVLEPIQGEGGVLPGQLEYLQGARKLCDEHNALLVFDEVQSGMGRSGHLFA
YMHYGVTPDILSSAKSIGGGFPLAAMLTTEKLARHFAVGVHGTTYGGNPLACAVGEAVIDVINTPEVLAGVQRKHQQFKT
RLQSIGQQYGVFSEVRGLGLLIGCVLSDAWKGKAKDIFNAAEAQDLMILQAGPDVIRFAPSLVIEDADIEEGLNRFERAI
AQLTS

Sequences:

>Translated_405_residues
MSVEHAAVQRADFDQVMVPNYAPAGFIPVRGAGSRVWDQAGRELVDFSGGIAVNVLGHCHPALVGALTEQANNLWHVSNV
FTNEPTLRLAKKLVDATFAERVFFCNSGAEANEAAFKLARRVAHDQYGPEKYEIIAALNSFHGRTLFTVSVGGQPKYSDG
FGPKITGISHVPYNDLDALKAAVTDKTCAVVLEPIQGEGGVLPGQLEYLQGARKLCDEHNALLVFDEVQSGMGRSGHLFA
YMHYGVTPDILSSAKSIGGGFPLAAMLTTEKLARHFAVGVHGTTYGGNPLACAVGEAVIDVINTPEVLAGVQRKHQQFKT
RLQSIGQQYGVFSEVRGLGLLIGCVLSDAWKGKAKDIFNAAEAQDLMILQAGPDVIRFAPSLVIEDADIEEGLNRFERAI
AQLTS
>Mature_404_residues
SVEHAAVQRADFDQVMVPNYAPAGFIPVRGAGSRVWDQAGRELVDFSGGIAVNVLGHCHPALVGALTEQANNLWHVSNVF
TNEPTLRLAKKLVDATFAERVFFCNSGAEANEAAFKLARRVAHDQYGPEKYEIIAALNSFHGRTLFTVSVGGQPKYSDGF
GPKITGISHVPYNDLDALKAAVTDKTCAVVLEPIQGEGGVLPGQLEYLQGARKLCDEHNALLVFDEVQSGMGRSGHLFAY
MHYGVTPDILSSAKSIGGGFPLAAMLTTEKLARHFAVGVHGTTYGGNPLACAVGEAVIDVINTPEVLAGVQRKHQQFKTR
LQSIGQQYGVFSEVRGLGLLIGCVLSDAWKGKAKDIFNAAEAQDLMILQAGPDVIRFAPSLVIEDADIEEGLNRFERAIA
QLTS

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=385, Percent_Identity=34.5454545454545, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=35.7859531772575, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=29.1764705882353, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI37574042, Length=414, Percent_Identity=26.3285024154589, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=26.6149870801034, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI226442705, Length=414, Percent_Identity=25.1207729468599, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI24119277, Length=399, Percent_Identity=27.5689223057644, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1789759, Length=403, Percent_Identity=65.7568238213399, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=60.3015075376884, Blast_Score=516, Evalue=1e-147,
Organism=Escherichia coli, GI1789016, Length=393, Percent_Identity=36.3867684478371, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI145693181, Length=393, Percent_Identity=34.8600508905852, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=34.6835443037975, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786991, Length=296, Percent_Identity=32.7702702702703, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786349, Length=339, Percent_Identity=29.2035398230088, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=36.0526315789474, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=452, Percent_Identity=29.2035398230088, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=263, Percent_Identity=36.8821292775665, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=435, Percent_Identity=24.8275862068966, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=36.875, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=437, Percent_Identity=22.6544622425629, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=393, Percent_Identity=39.9491094147583, Blast_Score=284, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6323470, Length=405, Percent_Identity=33.3333333333333, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6324386, Length=326, Percent_Identity=27.9141104294479, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357415, Length=392, Percent_Identity=34.1836734693878, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI161085790, Length=423, Percent_Identity=30.7328605200946, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28574759, Length=425, Percent_Identity=30.5882352941176, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356575, Length=417, Percent_Identity=28.537170263789, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI281366494, Length=435, Percent_Identity=22.2988505747126, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24667139, Length=435, Percent_Identity=22.2988505747126, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24667143, Length=435, Percent_Identity=22.2988505747126, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43458; Mature: 43327

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEHAAVQRADFDQVMVPNYAPAGFIPVRGAGSRVWDQAGRELVDFSGGIAVNVLGHCH
CCCCHHHHHHCCCCCEECCCCCCCCCEEECCCCCHHHHHHCHHHHHCCCCEEEEEHHHHH
PALVGALTEQANNLWHVSNVFTNEPTLRLAKKLVDATFAERVFFCNSGAEANEAAFKLAR
HHHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
RVAHDQYGPEKYEIIAALNSFHGRTLFTVSVGGQPKYSDGFGPKITGISHVPYNDLDALK
HHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AAVTDKTCAVVLEPIQGEGGVLPGQLEYLQGARKLCDEHNALLVFDEVQSGMGRSGHLFA
HHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEE
YMHYGVTPDILSSAKSIGGGFPLAAMLTTEKLARHFAVGVHGTTYGGNPLACAVGEAVID
EEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
VINTPEVLAGVQRKHQQFKTRLQSIGQQYGVFSEVRGLGLLIGCVLSDAWKGKAKDIFNA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AEAQDLMILQAGPDVIRFAPSLVIEDADIEEGLNRFERAIAQLTS
HCCCCEEEEECCCHHHHHCCHHEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVEHAAVQRADFDQVMVPNYAPAGFIPVRGAGSRVWDQAGRELVDFSGGIAVNVLGHCH
CCCHHHHHHCCCCCEECCCCCCCCCEEECCCCCHHHHHHCHHHHHCCCCEEEEEHHHHH
PALVGALTEQANNLWHVSNVFTNEPTLRLAKKLVDATFAERVFFCNSGAEANEAAFKLAR
HHHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
RVAHDQYGPEKYEIIAALNSFHGRTLFTVSVGGQPKYSDGFGPKITGISHVPYNDLDALK
HHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AAVTDKTCAVVLEPIQGEGGVLPGQLEYLQGARKLCDEHNALLVFDEVQSGMGRSGHLFA
HHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEE
YMHYGVTPDILSSAKSIGGGFPLAAMLTTEKLARHFAVGVHGTTYGGNPLACAVGEAVID
EEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
VINTPEVLAGVQRKHQQFKTRLQSIGQQYGVFSEVRGLGLLIGCVLSDAWKGKAKDIFNA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AEAQDLMILQAGPDVIRFAPSLVIEDADIEEGLNRFERAIAQLTS
HCCCCEEEEECCCHHHHHCCHHEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]