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The map label for this gene is ltaE [H]

Identifier: 66046786

GI number: 66046786

Start: 4237871

End: 4238875

Strand: Reverse

Name: ltaE [H]

Synonym: Psyr_3557

Alternate gene names: 66046786

Gene position: 4238875-4237871 (Counterclockwise)

Preceding gene: 66046788

Following gene: 66046785

Centisome position: 69.56

GC content: 64.18

Gene sequence:

>1005_bases
GTGACTGTCATCGATCTGCGCAGCGACACAGTGACTCTGCCCACGGCCGGCATGCTCGATGCCATGGCACGTGCGCCCGT
TGGCGATGATGTCTACGGCGAGGACCCTACCGTCAATCTGCTCGAAGCGACGCTTGCCGGACGCCTCGGGTTCGATGCCG
CGCTGTTCGTGCCGTCGGGCACCATGAGCAATCTGCTGGCACTGATGGCGCACTGTGAGCGTGGCGATGAGTACATCGTC
GGTCAGCAGGCCCACACCTATAAGTACGAGGGTGGTGGTGCGGCAGTGCTGGGCTCCATTCAGCCGCAGCCGCTGGAGGT
GCAGGCCGACGGCTCTCTGGACCTGCAGCAGGTGCTCGACGCCATCAAACCCGATGACTTTCACTTCGCCCGCACGCGCC
TGCTGGCCCTGGAAAACACCATGCAGGGCAAGGTGCTGCCCTTGGACTACCTGGCTGCCGCGCGTACCCTGACCCTGGAA
AAGGGGCTCGCCCTGCATCTGGACGGCGCGAGGCTGTACAACGCCGCGGTCAGGCTGGGTGTCGATGTCCATGAGATCAC
CCGGCACTTCGATTCGGTTTCGGTCTGCCTTTCCAAGGGGCTGGGCGCGCCGATCGGCTCGGTGCTGTGCGGTTCGCAGC
CGTTGATCGCCAAGGCCCGCCGCTTGCGCAAGATGCTTGGCGGTGGCATGCGTCAGGCTGGAGGGCTGGCTGCGGCAGGG
CTCTATGCGCTGGATCATCAGGTCGAGCGGTTGGCAGATGATCATGCCAACGCGGCGTTTCTGGCTGAAGGCCTGAGCGG
GCTCGGCTACCCTGTCGAGCCGGTACAGACCAATATGGTCTATGTGCAGATCGGCGAACGCGCGGCATCGCTCAAAGCGT
TCTGCGCCGAGCGGGGCATCGTACTCACGGCCGCGTCGCGGCTACGCATGGTGACCCACCTGAACGTGTCGCGCGCTCAG
GTCGAACAGGTCATCGCCGCATTCGCAGCCTTTGAACATTCATGA

Upstream 100 bases:

>100_bases
GCGGCGGCGCTTGATTATCATGTACTGCAGCCTCAGTAATGCCTTGTTGCAAGCCAAAGGTTGCATGCATTATCGATCTT
CAACTTCAGGGAGCTTTTTC

Downstream 100 bases:

>100_bases
CATGCCGATAATCCAGTTACTTGTTTCTATCGCACAAACACACTGTACCGAGGGCGCAACGCCTATATAATGCGGCCCTT
TGCCGTCGCTACGTCATTTG

Product: threonine aldolase

Products: NA

Alternate protein names: Low-specificity L-TA [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTVIDLRSDTVTLPTAGMLDAMARAPVGDDVYGEDPTVNLLEATLAGRLGFDAALFVPSGTMSNLLALMAHCERGDEYIV
GQQAHTYKYEGGGAAVLGSIQPQPLEVQADGSLDLQQVLDAIKPDDFHFARTRLLALENTMQGKVLPLDYLAAARTLTLE
KGLALHLDGARLYNAAVRLGVDVHEITRHFDSVSVCLSKGLGAPIGSVLCGSQPLIAKARRLRKMLGGGMRQAGGLAAAG
LYALDHQVERLADDHANAAFLAEGLSGLGYPVEPVQTNMVYVQIGERAASLKAFCAERGIVLTAASRLRMVTHLNVSRAQ
VEQVIAAFAAFEHS

Sequences:

>Translated_334_residues
MTVIDLRSDTVTLPTAGMLDAMARAPVGDDVYGEDPTVNLLEATLAGRLGFDAALFVPSGTMSNLLALMAHCERGDEYIV
GQQAHTYKYEGGGAAVLGSIQPQPLEVQADGSLDLQQVLDAIKPDDFHFARTRLLALENTMQGKVLPLDYLAAARTLTLE
KGLALHLDGARLYNAAVRLGVDVHEITRHFDSVSVCLSKGLGAPIGSVLCGSQPLIAKARRLRKMLGGGMRQAGGLAAAG
LYALDHQVERLADDHANAAFLAEGLSGLGYPVEPVQTNMVYVQIGERAASLKAFCAERGIVLTAASRLRMVTHLNVSRAQ
VEQVIAAFAAFEHS
>Mature_333_residues
TVIDLRSDTVTLPTAGMLDAMARAPVGDDVYGEDPTVNLLEATLAGRLGFDAALFVPSGTMSNLLALMAHCERGDEYIVG
QQAHTYKYEGGGAAVLGSIQPQPLEVQADGSLDLQQVLDAIKPDDFHFARTRLLALENTMQGKVLPLDYLAAARTLTLEK
GLALHLDGARLYNAAVRLGVDVHEITRHFDSVSVCLSKGLGAPIGSVLCGSQPLIAKARRLRKMLGGGMRQAGGLAAAGL
YALDHQVERLADDHANAAFLAEGLSGLGYPVEPVQTNMVYVQIGERAASLKAFCAERGIVLTAASRLRMVTHLNVSRAQV
EQVIAAFAAFEHS

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. L-threo-phenylserine and L- erythro-phenylserine are also good substrates [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=330, Percent_Identity=56.969696969697, Blast_Score=380, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI193206522, Length=345, Percent_Identity=43.768115942029, Blast_Score=253, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI193206524, Length=345, Percent_Identity=43.768115942029, Blast_Score=253, Evalue=9e-68,
Organism=Caenorhabditis elegans, GI193206520, Length=345, Percent_Identity=43.768115942029, Blast_Score=253, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6320789, Length=340, Percent_Identity=39.1176470588235, Blast_Score=204, Evalue=2e-53,
Organism=Drosophila melanogaster, GI21355439, Length=316, Percent_Identity=49.0506329113924, Blast_Score=267, Evalue=9e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 35485; Mature: 35354

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVIDLRSDTVTLPTAGMLDAMARAPVGDDVYGEDPTVNLLEATLAGRLGFDAALFVPSG
CEEEEECCCEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCC
TMSNLLALMAHCERGDEYIVGQQAHTYKYEGGGAAVLGSIQPQPLEVQADGSLDLQQVLD
CHHHHHHHHHHHCCCCCEEECCCCEEEEECCCCEEEEECCCCCCEEEECCCCCCHHHHHH
AIKPDDFHFARTRLLALENTMQGKVLPLDYLAAARTLTLEKGLALHLDGARLYNAAVRLG
HHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEECCCCEEEECCHHHHHHHHHHC
VDVHEITRHFDSVSVCLSKGLGAPIGSVLCGSQPLIAKARRLRKMLGGGMRQAGGLAAAG
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCHHHHH
LYALDHQVERLADDHANAAFLAEGLSGLGYPVEPVQTNMVYVQIGERAASLKAFCAERGI
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCE
VLTAASRLRMVTHLNVSRAQVEQVIAAFAAFEHS
EEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVIDLRSDTVTLPTAGMLDAMARAPVGDDVYGEDPTVNLLEATLAGRLGFDAALFVPSG
EEEEECCCEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCC
TMSNLLALMAHCERGDEYIVGQQAHTYKYEGGGAAVLGSIQPQPLEVQADGSLDLQQVLD
CHHHHHHHHHHHCCCCCEEECCCCEEEEECCCCEEEEECCCCCCEEEECCCCCCHHHHHH
AIKPDDFHFARTRLLALENTMQGKVLPLDYLAAARTLTLEKGLALHLDGARLYNAAVRLG
HHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEECCCCEEEECCHHHHHHHHHHC
VDVHEITRHFDSVSVCLSKGLGAPIGSVLCGSQPLIAKARRLRKMLGGGMRQAGGLAAAG
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCHHHHH
LYALDHQVERLADDHANAAFLAEGLSGLGYPVEPVQTNMVYVQIGERAASLKAFCAERGI
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCE
VLTAASRLRMVTHLNVSRAQVEQVIAAFAAFEHS
EEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]