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The map label for this gene is zraS [C]

Identifier: 66046761

GI number: 66046761

Start: 4209228

End: 4211303

Strand: Direct

Name: zraS [C]

Synonym: Psyr_3532

Alternate gene names: 66046761

Gene position: 4209228-4211303 (Clockwise)

Preceding gene: 66046760

Following gene: 66046762

Centisome position: 69.08

GC content: 61.08

Gene sequence:

>2076_bases
ATGAGCAATGATGTTTTTGGCGGCAGGCCATTCGCCCCCCAGCCACCCGTTCCCTCGGCGCAGGAAGCAGCCGAGCGGCT
GCAACTTGCCTTGGAGTCAGGGGCGGTTGTCGGTACCTGGGTGTGGGACATCATTGCCGATCAGTTGACCGGCGATGAGC
GTTTTGCCCGGACCTTCGGCTTGTGCCCGAAGCTGTGCGCCAAAGGTTTGCCACTGGAACTGGTGATTGCCTCCATTCAT
CCTGACGATTCGGCCAGAGTCGACAAGTCAATCGAGGAAGCGCTGCAGAGTAGCGAAACCTATCGATGCGAATACCGGGT
TCTCCATGAAGACGGTATTTATCGCTGGATCGAAGCCAGCGGAAGAATCGAACGCGACAGTCGTGGCAAACCCATTCGCA
GTCCGGGTGTATTGCTTGATATAGACGGCCGTCGCACTGCCGAAGACGAGCGCGACCGCCTCAACGAGTTGCTGAGAATA
TTCACAGCTGCCGTTCCCGGCGTTGTCTACGCCAAGGATCTCGAAGGTCGAATGCTGGTCGCCAATCGTGGCACCGCTGA
CCTGATCGGCAAGCCGCCCGAGTTTTTCATTGGCAAGACGGACCTGGAATTTCTGGATGATCAGGAACAGGCGCGGACGC
TCATGGAAACCGACCGCCGGATCATGCAGAGCAATGTCAGCGAACAGATTGAAGAACAGGTCAACCTGGCTGACGGCTCT
GCAGCGATATGGCTCTCGACCAAAGCGCCGCTGCTCGATGCCAGCGGCGACGTGATCGGTCTGATCGGCTCCTCTATCGA
TGTAACCGCCAGAAAAAAAGCCGAAGAAGCGGTCAGAGAACTCAACCAGACACTCGAACAGCGCATCGAACAAGCGGTTT
TCGAACGCGAGCAGATCGAAGACGCCCTGCGTCACTCGCAGAAGATGGATGCCGTCGGACAACTGACGGGGGGCATCGCC
CATGATTTCAACAACTTGCTGGCCGGCATTTCCGGCAGCCTGGAACTGATCACCAAACGCCTGGCCCAGGGCCGCGTCGG
TGACGTCGACCGTTACGTGTCGGTCGCCCAGGGCGCAGTACGCCGCGCCGCATCGCTGACCCACCGCCTGCTGGCGTTCT
CAAGACGCCAGACACTGTCGCCAAGAGTCACCGACGTGAACGGGTTGATTCATGACATGGAAGAGTTGATCGCGCGCACG
GTCGGCCCGGAGATAGACATCAAGGTCGTCGCCCATGATGACCTGTGGCCCGCGCTGATCGATCATGCCCAGCTGGAAAG
CTCGCTGCTTAACCTGTGCCTGAACGCCCGTGACGCAATGCCCAACGGCGGGCGCATTATCATCGAGACCGCCAATGCGT
CCCTCGAAGAGTGCACCGACCCGGATCACGGCATTCCTGCCGGCGAGCACCTGAGCATCCGCGTGACCGACACGGGCATC
GGCATGAGTCCGGACATCGCCGCCAAAGCCTTTGAACCGTTCTTCACCACCAAGGCCATCGGTGCCGGCACCGGTCTCGG
GCTGTCGATGGTGTATGGCTTTGTGCGCCAGTCCGGCGGGCAGATTCGCGTCGAGTCGGTCGAAGGCCAGGGCACCAGCG
TAGTCATGCACCTGCCCCGCCACACCGCTGAAAGCGCTCCGCGCCCCGTTGCGCCGGAAGTCATCGAAGAGCCGCCGCAT
CACACCGGCGAAACCGTTCTGGTCGTAGACGACGAACCCTCGGTGAGGATGCTCGTCGCCGAAGTCATCAGCGGTCTGGG
CTACAACTGCCTGGAAGCGGCAGACGCACAATCGGGCTTGCAGATCCTGCAGTCGGACACACGCATCGACCTGCTGATCA
GTGACATAGGCTTGCCAGGCGGCATGAACGGCCGGGAAATGGCCGATGCGGCCGGTGACTGTCGACCAGGCTTGCCGACC
CTGTTCATCACCGGTTACGCCAAGACATCCGTGCTGGACGATTGCCACCTGCGGCCTTGCACGCAAGTGCTGACCAAGCC
GTTCGGGCTGGACGCGCTGGCCGGGCGGGTGACAGGTCTGATCGGCGCTGACGCGGTCGCCCGCGGGTATTCGTGA

Upstream 100 bases:

>100_bases
CTGAAGCACAAAATAGAATAAATTTTGTACAACTTTCAGGCCGCTGCGCTGCCCTATGACTGAGTCTTTGTGAACCAGGC
GTTCAAGTGGGTCGATAGTG

Downstream 100 bases:

>100_bases
GGTGAACCCGACCACGCCTGATGGTCGGTATTTCGTGGTCAAGGGGCAACTCTGGCGGTGCTCCAATCCCTCCTTGAGCG
ACGACGTCCGCCAGCACCTT

Product: PAS

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MSNDVFGGRPFAPQPPVPSAQEAAERLQLALESGAVVGTWVWDIIADQLTGDERFARTFGLCPKLCAKGLPLELVIASIH
PDDSARVDKSIEEALQSSETYRCEYRVLHEDGIYRWIEASGRIERDSRGKPIRSPGVLLDIDGRRTAEDERDRLNELLRI
FTAAVPGVVYAKDLEGRMLVANRGTADLIGKPPEFFIGKTDLEFLDDQEQARTLMETDRRIMQSNVSEQIEEQVNLADGS
AAIWLSTKAPLLDASGDVIGLIGSSIDVTARKKAEEAVRELNQTLEQRIEQAVFEREQIEDALRHSQKMDAVGQLTGGIA
HDFNNLLAGISGSLELITKRLAQGRVGDVDRYVSVAQGAVRRAASLTHRLLAFSRRQTLSPRVTDVNGLIHDMEELIART
VGPEIDIKVVAHDDLWPALIDHAQLESSLLNLCLNARDAMPNGGRIIIETANASLEECTDPDHGIPAGEHLSIRVTDTGI
GMSPDIAAKAFEPFFTTKAIGAGTGLGLSMVYGFVRQSGGQIRVESVEGQGTSVVMHLPRHTAESAPRPVAPEVIEEPPH
HTGETVLVVDDEPSVRMLVAEVISGLGYNCLEAADAQSGLQILQSDTRIDLLISDIGLPGGMNGREMADAAGDCRPGLPT
LFITGYAKTSVLDDCHLRPCTQVLTKPFGLDALAGRVTGLIGADAVARGYS

Sequences:

>Translated_691_residues
MSNDVFGGRPFAPQPPVPSAQEAAERLQLALESGAVVGTWVWDIIADQLTGDERFARTFGLCPKLCAKGLPLELVIASIH
PDDSARVDKSIEEALQSSETYRCEYRVLHEDGIYRWIEASGRIERDSRGKPIRSPGVLLDIDGRRTAEDERDRLNELLRI
FTAAVPGVVYAKDLEGRMLVANRGTADLIGKPPEFFIGKTDLEFLDDQEQARTLMETDRRIMQSNVSEQIEEQVNLADGS
AAIWLSTKAPLLDASGDVIGLIGSSIDVTARKKAEEAVRELNQTLEQRIEQAVFEREQIEDALRHSQKMDAVGQLTGGIA
HDFNNLLAGISGSLELITKRLAQGRVGDVDRYVSVAQGAVRRAASLTHRLLAFSRRQTLSPRVTDVNGLIHDMEELIART
VGPEIDIKVVAHDDLWPALIDHAQLESSLLNLCLNARDAMPNGGRIIIETANASLEECTDPDHGIPAGEHLSIRVTDTGI
GMSPDIAAKAFEPFFTTKAIGAGTGLGLSMVYGFVRQSGGQIRVESVEGQGTSVVMHLPRHTAESAPRPVAPEVIEEPPH
HTGETVLVVDDEPSVRMLVAEVISGLGYNCLEAADAQSGLQILQSDTRIDLLISDIGLPGGMNGREMADAAGDCRPGLPT
LFITGYAKTSVLDDCHLRPCTQVLTKPFGLDALAGRVTGLIGADAVARGYS
>Mature_690_residues
SNDVFGGRPFAPQPPVPSAQEAAERLQLALESGAVVGTWVWDIIADQLTGDERFARTFGLCPKLCAKGLPLELVIASIHP
DDSARVDKSIEEALQSSETYRCEYRVLHEDGIYRWIEASGRIERDSRGKPIRSPGVLLDIDGRRTAEDERDRLNELLRIF
TAAVPGVVYAKDLEGRMLVANRGTADLIGKPPEFFIGKTDLEFLDDQEQARTLMETDRRIMQSNVSEQIEEQVNLADGSA
AIWLSTKAPLLDASGDVIGLIGSSIDVTARKKAEEAVRELNQTLEQRIEQAVFEREQIEDALRHSQKMDAVGQLTGGIAH
DFNNLLAGISGSLELITKRLAQGRVGDVDRYVSVAQGAVRRAASLTHRLLAFSRRQTLSPRVTDVNGLIHDMEELIARTV
GPEIDIKVVAHDDLWPALIDHAQLESSLLNLCLNARDAMPNGGRIIIETANASLEECTDPDHGIPAGEHLSIRVTDTGIG
MSPDIAAKAFEPFFTTKAIGAGTGLGLSMVYGFVRQSGGQIRVESVEGQGTSVVMHLPRHTAESAPRPVAPEVIEEPPHH
TGETVLVVDDEPSVRMLVAEVISGLGYNCLEAADAQSGLQILQSDTRIDLLISDIGLPGGMNGREMADAAGDCRPGLPTL
FITGYAKTSVLDDCHLRPCTQVLTKPFGLDALAGRVTGLIGADAVARGYS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=31.8897637795276, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1788549, Length=393, Percent_Identity=24.6819338422392, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI48994928, Length=567, Percent_Identity=22.3985890652557, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=250, Percent_Identity=30.4, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=294, Percent_Identity=25.5102040816327, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=280, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081816, Length=202, Percent_Identity=25.7425742574257, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74750; Mature: 74618

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDVFGGRPFAPQPPVPSAQEAAERLQLALESGAVVGTWVWDIIADQLTGDERFARTFG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCHHHHHHHHC
LCPKLCAKGLPLELVIASIHPDDSARVDKSIEEALQSSETYRCEYRVLHEDGIYRWIEAS
CCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEECCC
GRIERDSRGKPIRSPGVLLDIDGRRTAEDERDRLNELLRIFTAAVPGVVYAKDLEGRMLV
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEE
ANRGTADLIGKPPEFFIGKTDLEFLDDQEQARTLMETDRRIMQSNVSEQIEEQVNLADGS
ECCCCHHHCCCCCHHEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AAIWLSTKAPLLDASGDVIGLIGSSIDVTARKKAEEAVRELNQTLEQRIEQAVFEREQIE
EEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALRHSQKMDAVGQLTGGIAHDFNNLLAGISGSLELITKRLAQGRVGDVDRYVSVAQGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RRAASLTHRLLAFSRRQTLSPRVTDVNGLIHDMEELIARTVGPEIDIKVVAHDDLWPALI
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
DHAQLESSLLNLCLNARDAMPNGGRIIIETANASLEECTDPDHGIPAGEHLSIRVTDTGI
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHCCCCCCCCCCCCEEEEEEEECCC
GMSPDIAAKAFEPFFTTKAIGAGTGLGLSMVYGFVRQSGGQIRVESVEGQGTSVVMHLPR
CCCCCHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCC
HTAESAPRPVAPEVIEEPPHHTGETVLVVDDEPSVRMLVAEVISGLGYNCLEAADAQSGL
HHHHCCCCCCCCHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHCHHHHH
QILQSDTRIDLLISDIGLPGGMNGREMADAAGDCRPGLPTLFITGYAKTSVLDDCHLRPC
HHHHCCCCEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCEEEEECCHHHHHHCCCCCCHH
TQVLTKPFGLDALAGRVTGLIGADAVARGYS
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNDVFGGRPFAPQPPVPSAQEAAERLQLALESGAVVGTWVWDIIADQLTGDERFARTFG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCHHHHHHHHC
LCPKLCAKGLPLELVIASIHPDDSARVDKSIEEALQSSETYRCEYRVLHEDGIYRWIEAS
CCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEECCC
GRIERDSRGKPIRSPGVLLDIDGRRTAEDERDRLNELLRIFTAAVPGVVYAKDLEGRMLV
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEE
ANRGTADLIGKPPEFFIGKTDLEFLDDQEQARTLMETDRRIMQSNVSEQIEEQVNLADGS
ECCCCHHHCCCCCHHEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AAIWLSTKAPLLDASGDVIGLIGSSIDVTARKKAEEAVRELNQTLEQRIEQAVFEREQIE
EEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DALRHSQKMDAVGQLTGGIAHDFNNLLAGISGSLELITKRLAQGRVGDVDRYVSVAQGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RRAASLTHRLLAFSRRQTLSPRVTDVNGLIHDMEELIARTVGPEIDIKVVAHDDLWPALI
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
DHAQLESSLLNLCLNARDAMPNGGRIIIETANASLEECTDPDHGIPAGEHLSIRVTDTGI
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHCCCCCCCCCCCCEEEEEEEECCC
GMSPDIAAKAFEPFFTTKAIGAGTGLGLSMVYGFVRQSGGQIRVESVEGQGTSVVMHLPR
CCCCCHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCC
HTAESAPRPVAPEVIEEPPHHTGETVLVVDDEPSVRMLVAEVISGLGYNCLEAADAQSGL
HHHHCCCCCCCCHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHCHHHHH
QILQSDTRIDLLISDIGLPGGMNGREMADAAGDCRPGLPTLFITGYAKTSVLDDCHLRPC
HHHHCCCCEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCEEEEECCHHHHHHCCCCCCHH
TQVLTKPFGLDALAGRVTGLIGADAVARGYS
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA